Personal profile
Biography
Carole Torsney graduated with a 1st class Honours degree in Neuroscience from the University of Glasgow before completing a Wellcome Trust Neuroscience 4 yr PhD with Prof Maria Fitzgerald, University College London. She then undertook postdoctoral research with Prof Amy MacDermott, Columbia University, USA. In 2006, she successfully obtained a Caledonian Research Fellowship to undertake research within the Centre for Integrative Physiology, University of Edinburgh which was then furthered by a University of Edinburgh Senior Academic Fellowship. She currently continues her research interests within the Centre for Integrative Physiology, as a Lecturer in Biomedical Sciences.
Qualifications
1997, University of Glasgow, BSc Hons Neuroscience (1st class)
2002, University College London (UCL), PhD
Research Interests
Our main research focus is investigation of the altered sensory processing or ‘plasticity’ that occurs in chronic pain conditions with the aim of identifying novel therapies.
My research in a nutshell
Pain is an essential warning system that promotes survival. However, following injury, some individuals develop chronic ongoing pain that can be evoked by everyday activities and can even occur spontaneously, which greatly reduces quality of life. Unfortunately, treatment options for these conditions are frequently ineffective or are limited by adverse side effects. We strive to improve our understanding of the mechanisms underlying this altered neural communication within the pain pathways, in conjunction with clinical colleagues through the University of Edinburgh Translational Pain Research Programme, with the aim of improving management of these debilitating conditions:
http://www.ed.ac.uk/integrative-physiology/staff-profiles/research-groups/carole-torsney
Teaching
Carole Torsney is the Course Organiser for Medical Biology 1 (300+ students) and Course Organiser of an Honours Elective (Sensory Physiology and Dysfunction) and teaches on both of these courses. She also organises and contributes to a themed week of teaching for the ‘MSc by Research Integrative Neuroscience’. In addition she is a member of the Physiology Honours Exam Board. Her teaching spans all undergraduate years and also postgraduate:
Undergraduate
Year 1: Medical Biology 1
Year 2: Biomedical Sciences 2
Year 3: Biomedical Sciences 3, Neuroscience 3
Year 4: Sensory Physiology and Dysfunction
Postgraduate (MSc): MSc by Research Integrative Neuroscience
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Collaborations and top research areas from the last five years
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Postsurgical tactile-evoked pain: a role for brain-derived neurotrophic factor-tropomyosin receptor kinase B–dependent novel tactile corpuscles
Wilson, K., Sze, Y., Regan, A., Zhu, C., Mazur, K., Velichkova, A. N. & Torsney, C., Oct 2024, In: Pain Reports. 9, 5, e1169.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Childhood reading ability and pain in childhood through to midlife
Bridges, E. C., Torsney, C., Bates, T. C. & Luciano, M., Aug 2024, In: The Journal of Pain. 25, 8, 16 p., 104518.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
LGI3/2-ADAM23 interactions cluster Kv1 channels in myelinated axons to fine-tune axonal properties
Kozar-Gillan, N., Velichkova, A., Kanatouris, G., Eshed-Eisenbach, Y., Steel, G., Jaegle, M., Aunin, E., Peles, E., Torsney, C. & Meijer, D. N., 24 Feb 2023, In: Journal of Cell Biology. 222, 4, 21 p., e202211031.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
LGI3/2-ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period
Kozar, N., Velichkova, A., Kanatouris, G., Eshed-Eisenbach, Y., Steel, G., Jaegle, M., Aunin, E., Peles, E., Torsney, C. & Meijer, D., 24 Feb 2023, In: Journal of Cell Biology. 222, 4, 21 p., e202211031.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Post-operative pain facilitates rat C-fibre activity-dependent slowing and induces thermal hypersensitivity in a sex-dependent manner
Velichkova, A., Colman, S. E. & Torsney, C., 1 Apr 2022, In: British Journal of Anaesthesia. 128, 4, p. 718-733Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Optimizing translation of a novel skin target for post-surgical pain
Torsney, C. (Principal Investigator)
British Journal Of Anaesthesia
1/10/25 → 7/12/26
Project: Research
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Carnegie Trust
Torsney, C. (Principal Investigator), Fleetwood-Walker, S. (Co-investigator) & Shipston, M. (Co-investigator)
Other Competitive Uk Charity Sources
1/06/06 → …
Project: Research
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Post-surgical tactile pain – investigating the origin of novel tactile innervation
Torsney, C. (Principal Investigator)
3/06/24 → 14/07/24
Project: Research
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Investigating how cancer alters behavior via regulating the internal sensory system
Torsney, C. (Principal Investigator)
The Carnegie Trust for the Universities of Scotland
15/05/24 → 6/08/24
Project: Research
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Preliminary assessment of the utility of melatonin for diabetic neuropathic pain
Torsney, C. (Principal Investigator)
1/01/21 → 1/05/21
Project: Research