Research output per year
Research output per year
Personal profile
Biography
Chengcan Yao received his PhD in Biomedical Science from Kyoto University at 2010. He then did his post-doc with Professor Shuh Narumiya at Kyoto University as a JSPS (Japan Society for the Promotion of Science) Research Fellow for Overseas Researchers. From 2013, Chengcan established his independent research at the MRC Centre for Inflammation Research (CIR) in the University of Edinburgh as a Chancellor's Fellowship.
Qualifications
BSc, MSc, PhD
Websites
Current Research Interests
Bioactive lipids in inflammation and immunity
Collaborative Activity
Prof Shuh Narumiya (Kyoto Univ), Prof Richard Breyer (Vanderbilt Univ), Rick Maizels (Glasgow Univ) and many groups within the University of Edinburgh
Research students
PhD student
Teaching
Honour student mini projects, C1&H3A Wikis
Office Hours
9am-5pm, Mon-Fri
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
Crittenden, S., Goepp, M., Pollock, J., Robb, C., Smyth, D. J., Zhou, Y., Andrews, R., Tyrrell, V., Gkikas, K., Adima, A., O'Connor, R. A., Davies, L., Li, X.-F., Yao, H. X., Ho, G.-T., Zheng, X., Mair, A., Vermeren, S., Qian, B.-Z. & Mole, D. J. & 12 others, , 12 Feb 2021, In: Science Advances.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
T cell–intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell–driven inflammation
Lee, J., Aoki, T., Thumkeo, D., Siriwach, R., Yao, C. & Narumiya, S., 1 Feb 2019, In: Journal of Allergy and Clinical Immunology. 143, 2, p. 631-643Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Facilitation of IL-22 production from innate lymphoid cells by prostaglandin E2 prevents experimental lung neutrophilic inflammation
Felton, J. M., Duffin, R., Robb, C. T., Crittenden, S., Anderton, S. M., Howie, S. E. M., Whyte, M. K. B., Rossi, A. G. & Yao, C., 24 Mar 2018, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Letter › peer-review
Open AccessFile -
Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis
Robb, C. T., McSorley, H. J., Lee, J., Aoki, T., Yu, C., Crittenden, S., Astier, A., Felton, J. M., Parkinson, N., Ayele, A., Breyer, R. M., Anderton, S. M., Narumiya, S., Rossi, A. G., Howie, S., Guttman-Yassky, E., Weller, R. B. & Yao, C., 3 Jun 2017, In: Journal of Allergy and Clinical Immunology. 141, 1, p. 152-162Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis
Duffin, R., O'Connor, R. A., Crittenden, S., Forster, T., Yu, C., Zheng, X., Smyth, D., Robb, C. T., Rossi, F., Skouras, C., Tang, S., Richards, J., Pellicoro, A., Weller, R. B., Breyer, R. M., Mole, D. J., Iredale, J. P., Anderton, S. M., Narumiya, S. & Maizels, R. M. & 4 others, , 18 Mar 2016, In: Science. 351, 6279, p. 1333-1338 6 p.Research output: Contribution to journal › Article › peer-review
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Defining a specific IL-22-mediated pathway in regulating eczema
Weller, R. (Principal Investigator) & Yao, C. (Co-investigator)
1/02/19 → 31/08/25
Project: Research
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Exploring physiological impacts for bioactive lipids on mucosal immune functions during ageing
Yao, C. (Principal Investigator), Zhou, Y. (Co-Investigator (External)) & Rossi, A. (Co-investigator)
1/10/20 → 30/09/24
Project: Research
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Single cell definition of the mechanistic role of kynurenine monooxygenase at the innate immune interface in acute pancreatitis.
Mole, D. (Principal Investigator), Ramachandran, P. (Co-investigator) & Yao, C. (Co-investigator)
7/08/19 → 6/08/22
Project: Research
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Single cell definition of the mechanistic role of kynurenine monooxygenase at the innate immune interface in acute pancreatitis.
Mole, D. (Principal Investigator), Ramachandran, P. (Co-investigator) & Yao, C. (Co-investigator)
7/08/19 → 6/08/22
Project: Research
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Defining a specific IL-22-mediated pathway in regulating eczema
Yao, C. (Principal Investigator) & Weller, R. (Co-investigator)
UK central government bodies/local authorities, health and hospital authorities
1/02/19 → 16/07/23
Project: Research
Press/Media
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New genetic clues to Crohn's disease unravelled in Edinburgh hotspot
15/03/21
1 item of Media coverage
Press/Media: Research
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Dr Chengcan Yao shows how the gut keeps deadly infections at bay
17/03/16
14 items of Media coverage
Press/Media: Research