Professor Chris Gregory holds the Chair of Inflammatory Cell Biology and is Deputy Director of the MRC Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh. He leads the Inflammation and Cancer Group in the Centre and has a research track record spanning more than two decades in the field of apoptosis and especially apoptotic cell clearance. 

Immune Modulation and Regulation of Inflammation, Tissue Remodelling and Regeneration

In this video Chris describes how cell birth and cell death are normally kept in balance in our tissues but, in cancer, imbalances favouring expansion of cell populations occur. His research investigates the underlying mechanisms and, in particular, how dying tumour cells can drive expansion of malignant cell populations. 

Chris Gregory: Cell death in cancer

Group Members:

• Dr Margaret Paterson (Postdoctoral Research Fellow)
• Lynsey Melville (Technician)
• Catherine Lynch (PhD student, co-supervised with Dr Colin Campbell, School of Chemistry)
• Maria Panagopoulou (PhD student)

Professor Chris Gregory has particular interests in the regulation of apoptosis in tumours, especially non-Hodgkin lymphomas, the mechanisms underlying the interaction of apoptotic tumour cells with innate immune cells including tumour-associated macrophages, the consequences of such interactions for anti-tumour immunity and the manipulation of these mechanisms for therapeutic gain. Core support for current research activities is currently provided mainly through a Specialist Programme from Leukaemia and Lymphoma Research and from the MRC.