Christopher Haslett

Search results

• Active

  Clinical Validation of Optical Molecular Alveoscopy for the Immediate Bed-Side Diagnosis of Pneumonia in the Intensive Care Unit

  Dhaliwal, K. (Principal Investigator), Akram, A. (Co-investigator), Craven, T. (Co-investigator), Haslett, C. (Co-investigator), Parker, R. (Co-investigator), Walsh, T. (Co-investigator) & Williams, C. (Co-investigator)

  UK-based charities

  1/07/20 → 1/07/26

  Project: Research

  • Keratitis 100%
  • Point of Care Systems 100%
  • Ex Vivo 42%
  • Health Care Cost 14%
  • Invasive Diagnostics 14%
• Finished

  EPSRC IRC Proteus - Multiplexed 'Touch and Tell' Optical Molecular Sensing and Imaging - Lifetime and Beyond

  Bradley, M. (Principal Investigator), Bradley, M. (Principal Investigator), Dhaliwal, K. (Co-investigator), Dhaliwal, K. (Co-investigator), Haslett, C. (Co-investigator), Henderson, R. (Co-investigator), Walsh, T. (Co-investigator) & Walsh, T. (Co-investigator)

  Engineering and Physical Sciences Research Council

  1/01/19 → 1/06/23

  Project: Research

  • Fluorescence Lifetime 100%
  • Biological Tissue 36%
  • Imaging Systems 33%
  • Spectroscopy 28%
  • Complementary Metal-Oxide-Semiconductor 27%

• Interventional Biophotonics ¿¿¿ A UK Healthcare Technology Accelerator Facility

  Dhaliwal, K. (Principal Investigator), Bradley, M. (Co-investigator), Bruce, A. (Co-investigator), Garden, J. (Co-investigator), Haslett, C. (Co-investigator), Henderson, R. (Co-investigator), Mair, J. (Co-investigator), Moore, A. (Co-investigator), Newby, D. (Co-investigator), Tait, J. (Co-investigator) & Walsh, T. (Co-investigator)

  MRC

  1/03/18 → 29/02/20

  Project: Research

• Proteus Participation in CARB-X

  Walsh, T. (Principal Investigator), Dhaliwal, K. (Co-investigator) & Haslett, C. (Co-investigator)

  Non-EU other

  1/04/17 → 31/07/19

  Project: Research

  • Confocal Laser Scanning Microscopy 100%
  • Ex Vivo 100%
  • Lung 100%
  • Fluorescence Microscopy 100%
  • Bacterium Detection 100%

• Optimising Innate Host Defence to Combat Antimicrobial Resistance

  Dockrell, D. (Principal Investigator), Baillie, K. (Co-investigator), Bradley, M. (Co-investigator), Brown, H. (Co-investigator), Dhaliwal, K. (Co-investigator), Fitzgerald, R. (Co-investigator), Haslett, C. (Co-investigator), Hume, D. (Co-investigator), Rossi, A. (Co-investigator), Walmsley, S. (Co-investigator) & Whyte, M. (Co-investigator)

  MRC

  1/12/16 → 30/11/22

  Project: Research

  • Staphylococcus Aureus 100%
  • Macrophage 52%
  • Legionella pneumophila 34%
  • Mouse Model 34%
  • Pathogenicity 34%

• Ahsan Akram - Scottish Alliance Framework Agreement

  Haslett, C. (Principal Investigator)

  Scottish Power

  1/09/14 → 31/08/15

  Project: Research

• Ahsan Akram - Scottish Alliance Framework Agreement

  Frame, M. (Principal Investigator), Ball, K. (Co-investigator), Brunton, V. (Co-investigator) & Haslett, C. (Co-investigator)

  UK industry, commerce and public corporations

  1/09/14 → 31/07/17

  Project: Research

• Molecular Probes to Define the Pulmonary Macrophage Response in Rat and Man

  Dhaliwal, K. (Principal Investigator), Haslett, C. (Co-investigator) & Vendrell Escobar, M. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  15/12/13 → 14/06/14

  Project: Research

• Multiplexed 'Touch and Tell' Optical Molecular Sensing and Imaging

  Haslett, C. (Principal Investigator)

  EPSRC

  1/10/13 → 31/03/19

  Project: Research

  • Lung 100%
  • Ex Vivo 63%
  • Endomicroscopy 55%
  • Imaging Technique 46%
  • Leukocyte Activation 46%

• DEVELOPMENTAL CLINICAL STUDIES-VALIDATION OF THE UTILITY OF A NOVEL SMARTPROBE DETECTING NEUTROPHIL ACTIVATION/ELASTASE ACTIVITY IN ACUTE LUNG INJURY

  Haslett, C. (Principal Investigator), Dhaliwal, K. (Co-investigator) & Walsh, T. (Co-investigator)

  MRC

  1/08/13 → 31/07/16

  Project: Research

  • Lung 100%
  • Imaging Technique 100%
  • Leukocyte Activation 100%
  • Neutrophil 100%
  • Drug Microdose 50%

• The role of cyclin-dependent kinase-9 inhibition in promoting the resolution of chronic inflammation

  Rossi, A. (Principal Investigator) & Haslett, C. (Co-investigator)

  MRC

  1/05/13 → 30/10/19

  Project: Research

  • Neutrophil 100%
  • Inflammation 59%
  • Macrophage 44%
  • Programmed Cell Death 32%
  • Inflammation Response 32%

• A new paradigm for testing pathway tractability in lung disease

  Hirani, N. (Principal Investigator), Dhaliwal, K. (Co-investigator) & Haslett, C. (Co-investigator)

  MRC

  1/05/13 → 30/06/17

  Project: Research

  • Neutrophil 100%
  • Cytokine Production 66%
  • Autofluorescence 66%
  • Pulmonary Inflammation 66%
  • Peripheral Blood Mononuclear Cell 66%

• Molecular Optical Imaging of Key Targets in the Fibrogenic Pathway in Man

  Bradley, M. (Principal Investigator), Dhaliwal, K. (Co-investigator), Haslett, C. (Co-investigator), Hirani, N. (Co-investigator) & McGorum, B. (Co-investigator)

  MRC

  1/09/12 → 31/12/15

  Project: Research

  • Lung 100%
  • Thrombin 68%
  • Molecular Imaging 57%
  • Neutrophil 51%
  • Ex Vivo 45%

• Immediate Point of Care Molecular Diagnostics for Lung Inflammation/Infection in Critical Care

  Haslett, C. (Principal Investigator) & Bradley, M. (Co-investigator)

  UK-based charities

  1/09/11 → 30/04/16

  Project: Research

• THE AMY-LTAB TRANSGENIC MOUSE MODEL OF TERTIARY LYMPHOID PRGAN-INDUCED NON-HODGLIN'S LYMPHOMA

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/07/11 → 30/06/13

  Project: Research

• In vivo Chemistry

  Bradley, M. (Principal Investigator), Frame, M. (Co-investigator) & Haslett, C. (Co-investigator)

  EPSRC

  1/12/10 → 29/02/12

  Project: Research

• LSRll Flow Cytometer and a FACSAria II Cell Sorter for QMRI

  Anderton, S. (Principal Investigator), Ffrench-Constant, C. (Co-investigator), Gregory, C. (Co-investigator), Haslett, C. (Co-investigator) & Saunders, P. (Co-investigator)

  UK-based charities

  1/02/10 → 31/01/15

  Project: Research

  • Immunotherapy 100%
  • Peptides 50%
  • Experimental Autoimmune Encephalomyelitis 50%
  • T Cell 50%
  • Immune Tolerance 14%

• Functional Optical Imagingin Mouse and Man

  Mole, D. (Principal Investigator), Auer, M. (Co-investigator), Bradley, M. (Co-investigator), Dhaliwal, K. (Co-investigator), Harrison, E. (Co-investigator), Haslett, C. (Co-investigator), Mowat, C. (Co-investigator), Simpson, J. (Co-investigator), Walkinshaw, M. (Co-investigator) & Wigmore, S. (Co-investigator)

  MRC

  1/10/09 → 31/03/12

  Project: Research

  • Cellular Imaging 100%
  • Fluorescence Resonance Energy Transfer 100%
  • Serine Protease 100%
  • Peptoid 100%
  • Cell Labeling 100%

• Molecular Imaging in the Lung

  Haslett, C. (Principal Investigator) & Newby, D. (Co-investigator)

  UK-based charities

  1/04/09 → 31/03/10

  Project: Research

• Multimodal smart imaging of critical inflammatory processes in murine models of pulmonary fibrosis

  Haslett, C. (Principal Investigator), Bradley, M. (Co-investigator) & Simpson, J. (Co-investigator)

  MRC

  2/02/09 → 1/02/12

  Project: Research

  • Fluorescence Resonance Energy Transfer 100%
  • Cellular Imaging 100%
  • Serine Protease 100%
  • Diseases 100%
  • Inflammation 100%

• CDK inhibition therapy and potential for novel imaging biomarkers in idiopathic pulmonary fibrosisCDK inhibition therapy and potential for novel imaging biomarkers in idiopathic pulmonary fibrosis

  Haslett, C. (Principal Investigator), Hirani, N. (Co-investigator) & Rossi, A. (Co-investigator)

  MRC

  1/12/08 → 30/11/11

  Project: Research

  • Contact Dermatitis 100%

• Clinical Research Imaging Centre

  Newby, D. (Principal Investigator), Bastin, M. (Co-investigator), Critchley, H. (Co-investigator), Deary, I. (Co-investigator), Fox, K. (Co-investigator), Haslett, C. (Co-investigator), Johnstone, E. (Co-investigator), Seckl, J. (Co-investigator), Walker, B. (Co-investigator), Wardlaw, J. (Co-investigator) & Wilmut, I. (Co-investigator)

  MRC

  1/08/08 → 31/07/13

  Project: Research

  • Magnetic Resonance Imaging 100%
  • Aortic Stenosis 75%
  • Image Quality 75%
  • Positron Emission Tomography-Computed Tomography 75%
  • Coronary Angiography 68%

• The role of Mcl-1 in CDK inhibitor-mediated neutrophil apoptosis and enhanced resolution of bleomycin induced lung injury

  Rossi, A. (Principal Investigator) & Haslett, C. (Co-investigator)

  UK-based charities

  1/11/07 → 31/10/10

  Project: Research

• Regulation of pulmonary inflammation : the role of P2X7 receptors in LL-37-mediated control of granulocyte apoptosis and function

  Davidson, D. (Principal Investigator) & Haslett, C. (Co-investigator)

  1/10/07 → 30/09/11

  Project: University Awarded Project Funding

• can long term nebulised gentamicin reduce the bacterial burden, break the vicious cycle of inflammation and improve quality of life in patients with brochiectasis

  Simpson, J. (Principal Investigator), Govan, J. (Co-investigator) & Haslett, C. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  1/05/07 → 30/06/10

  Project: Research

• The role of the human cathelicidin LL-37 as an immunomodulator in infcetious lung disease. RCD Fellowship for Dr D J Davidson

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/03/06 → 28/02/10

  Project: Research

• The role of macrophaged in ischaemic acute renal failure.

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/10/05 → 30/09/08

  Project: Research

• Shert/Cruden Medical Research Scholarship Dr A MacDuff: The role of the tissue macrophage in the sensing and regulation of hypoxic/hyperoxic tissue injury

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/11/04 → 30/07/06

  Project: Research

• Edinburgh centre for inflammation research

  Savill, J. (Principal Investigator) & Haslett, C. (Co-investigator)

  MRC

  30/09/04 → 30/09/10

  Project: Research

  • Hydroxysteroid Dehydrogenase 100%
  • Glucocorticoid 92%
  • Mast Cell 50%
  • Mast Cell Degranulation 50%
  • Serositis 50%

• Internationl Prize Fellowship for Donald J Davidson: The role of host defence peptide LL-37 in modulation cell differentitation ans the inate and acquired host immune responses

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/08/04 → 30/07/06

  Project: Research

• Elafin overexpression and myocardial protection.

  Gray, G. (Principal Investigator), Haslett, C. (Co-investigator), Sallenave, J. (Co-investigator) & Webb, D. (Co-investigator)

  UK-based charities

  1/07/03 → 30/06/04

  Project: Research

• Activation and increased longevity of Eosinophils in Hypoxic conditions

  Rossi, A. (Principal Investigator), Dransfield, I. (Co-investigator) & Haslett, C. (Co-investigator)

  UK-based charities

  1/07/02 → 30/06/05

  Project: Research

  • Glucocorticoid 100%
  • Neutrophil 100%
  • Granulocyte Macrophage Colony-Stimulating Factor 27%
  • Programmed Cell Death 27%
  • Inflammatory Cytokine 18%

• Mechanisms underlying RAF medicated integrin suppression

  Sethi, T. (Principal Investigator), Haslett, C. (Co-investigator) & Lad, Y. (Co-investigator)

  UK-based charities

  1/05/02 → 30/04/04

  Project: Research

• Fellowship - Dr Stuart McKechnie

  Harrison, D. (Principal Investigator), Haslett, C. (Co-investigator) & Salter, D. (Co-investigator)

  UK-based charities

  1/04/02 → 31/03/05

  Project: Research

• New Programme Grant to pump-prime Pulmonary Cellular & Molecular Imagining in Edinburgh

  Haslett, C. (Principal Investigator)

  Other

  1/02/02 → 30/06/13

  Project: Research

• Role of protein inhibitors in innate immunity

  Sallenave, J. (Principal Investigator) & Haslett, C. (Co-investigator)

  UK-based charities

  1/02/02 → 31/01/05

  Project: Research

• Use od Adeno-associated virus (AAV) as a gene delivery vector in murine emphyema models.

  Sallenave, J. (Principal Investigator) & Haslett, C. (Co-investigator)

  Other

  1/12/01 → 30/11/03

  Project: Research

• FELLOWSHIP DR S HART

  Haslett, C. (Principal Investigator)

  MRC

  1/10/01 → 30/09/06

  Project: Research

• Fellowship - Dr J McCafferty

  Haslett, C. (Principal Investigator) & McCafferty, J. (Co-investigator)

  UK-based charities

  1/08/01 → 31/07/03

  Project: Research

• Prize Fellowship for Marta Corsin-Jiminez

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/03/01 → 31/12/02

  Project: Research

• Lung epithelial cell protection mechanisms in sequential hypoxic/hyperoxic injury

  Haslett, C. (Principal Investigator) & Harrison, D. (Co-investigator)

  UK-based charities

  1/02/01 → 31/01/04

  Project: Research

• The sheep as a model for antiprotease gene therapy in emphysema

  Collie, D. (Principal Investigator), Haslett, C. (Co-investigator) & Sallenave, J. (Co-investigator)

  UK-based charities

  1/10/00 → 30/09/05

  Project: Research

• Clinical Training Fellowship for Dr L Murray. The role of neutrophil death factors (including Fas/Fas-ligand) in the control of

  Haslett, C. (Principal Investigator)

  MRC

  1/08/00 → 31/07/03

  Project: Research

• Genetic augmentation of small molecular weight antiproteinases as a cytoprotective strategy in inflammatory lung injury

  Haslett, C. (Principal Investigator) & Sallenave, J. (Co-investigator)

  MRC

  1/06/00 → 31/05/03

  Project: Research

• BACTERIAL INFECTION - LUNG

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/09/99 → 31/03/02

  Project: Research

• Laboratory-based test of fitness to drive

  Douglas, N. (Principal Investigator), Engleman, H. (Co-investigator) & Haslett, C. (Co-investigator)

  UK-based charities

  1/08/99 → 31/07/02

  Project: Research

• LEUKOTRIENES/GRANUL APOPTOSIS

  Haslett, C. (Principal Investigator) & Rossi, A. (Co-investigator)

  UK industry, commerce and public corporations

  1/12/98 → 30/11/00

  Project: Research

• Clostridium difficile and herd immunity: developing control strategies by inferential stochastic modelling

  Poxton, I. (Principal Investigator), Fox, K. (Co-investigator), Haslett, C. (Co-investigator), Mullins, J. (Co-investigator), Seckl, J. (Co-investigator) & Webb, D. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  1/10/98 → 30/09/01

  Project: Research

• ADV F/SHIP FOR MED & DENT GRAD

  Haslett, C. (Principal Investigator)

  UK-based charities

  1/08/98 → 31/07/01

  Project: Research

• Wellcome Cardiovascular Initiative

  Fox, K. (Principal Investigator), Haslett, C. (Co-investigator), Mullins, J. (Co-investigator), Seckl, J. (Co-investigator) & Webb, D. (Co-investigator)

  UK-based charities

  1/02/98 → 30/09/10

  Project: Research