Personal profile


Experienced health services researcher and clinical trials methodologist, co-leading the statistical work of the Edinburgh Clinical Trials Unit.  Role involves collaboration with clinical investigators to deliver high impact clinical trials and health research studies, alongside development of novel statistical clinical trials methodology to support current and future research.

Current Research Interests

  • Design and analysis of cluster-randomised trials, including stepped-wedge designs
  • Statistical methods for the evaluation of potential surrogate outcomes in clinical trials
  • Adaptive design clinical trials

Education/Academic qualification

Public Health and Health Services Research, Master of Science, Use of sequential treatment allocation methods and patient-specific outcome measures in a trial of glycaemic control in acute stroke, University of Aberdeen

1 Oct 199631 Aug 1997

Award Date: 1 Dec 1997

Statistics, Doctor of Philosophy (PhD), Informed clinical management of acute stroke: use of established statistical methods and development of an expert system, University of Glasgow

1 Oct 199330 Sept 1996

Award Date: 1 Jul 1997

Statistics, Bachelor of Science, University of Glasgow

1 Oct 198931 May 1993

Award Date: 1 Jul 1993

External positions

Member, Efficacy and Mechanisms Evaluation Committee, NIHR

Jun 2018Jun 2022

Member, Commission on Human Medicines, MHRA

Dec 2014 → …

Member, Health Services and Delivery Research Board, National Institute for Health Research

Nov 2013May 2018

Associate Editor, Clinical Trials, Society for Clinical Trials

Jul 2013 → …

Clinical Trials, Biologics and Vaccines Expert Advisory Group , MHRA

Jan 2011Dec 2020

Neurology, Pain and Psychiatry Expert Advisory Group , MHRA

Jan 2011 → …


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