Research output per year
Research output per year
Personal profile
Education/Academic qualification
Neuroscience, Doctor of Philosophy (PhD), Modelling Alzheimer's Disease in Organotypic Slices, University of Cambridge
Oct 2013 → Oct 2016
Award Date: 14 Dec 2016
Natural Sciences, Bachelor of Arts, Natural Sciences- Part II Neuroscience-1st Class, University of Cambridge
Oct 2010 → Jun 2013
Award Date: 20 Jun 2013
External positions
Postdoctoral Researcher, University of Cambridge
Oct 2016 → Aug 2019
Fingerprint
Dive into the research topics where Claire Durrant is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease
Colom Cadena, M., Toombs, J., Simzer, E., Holt, K., McGeachan, R., Tulloch, J., Jackson, R. J., Catterson, J. H., Spires-Jones, M. P., Rose, J., Waybright, L., O Caggiano, A., King, D., Gobbo, F., Davies, C., Hooley, M., Dunnett, S., Tempelaar, R., Meftah, S. & Tzioras, M. & 7 others, , 6 Feb 2024, In: Acta Neuropathologica. 147, p. 1-22Research output: Contribution to journal › Article › peer-review
Open AccessFile -
p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003
Taylor, L. W., Simzer, E. M., Pimblett, C., Lacey-Solymar, O. T. T., McGeachan, R. I., Meftah, S., Rose, J. L., Spires-Jones, M. P., Holt, K., Catterson, J. H., Koch, H., Liaquat, I., Clarke, J. H., Skidmore, J., Smith, C., Booker, S. A., Brennan, P. M., Spires-Jones, T. L. & Durrant, C. S., 4 Jan 2024, In: Acta Neuropathologica. 147, 1, p. 7Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue
Miller, L., Mukadam, A., Durrant, C., Vaysburd, M., Katsinelos, T., Tuck, B., Sanford, S., Sheppard, O., Knox, C., Cheng, S., James, L., Coleman, M. & McEwan, W., 12 Mar 2021, In: Acta Neuropathologica Communications. 9, 41, 16 p., 41.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics
Kent, S., Spires-Jones, T. & Durrant, C., 29 Jul 2020, (E-pub ahead of print) In: Acta Neuropathologica.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Preparation of organotypic hippocampal slice cultures for the study of CNS disease and damage
Durrant, C., 11 Jun 2020, (E-pub ahead of print) Axon Degeneration. Babetto, E. (ed.). Springer, p. 133-144 11 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Prizes
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1st place team at Dementia Research Meets Motorsport Innovation Accelerator
Durrant, C. (Recipient), 6 Jul 2021
Prize: Prize (including medals and awards)
File -
Race Against Dementia Fellowship
Durrant, C. (Recipient), 1 Sept 2019
Prize: Fellowships awarded competitively
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SULSA ECR Prize 2020 (Understanding & Treating Disease)
Durrant, C. (Recipient), 16 Sept 2020
Prize: Prize (including medals and awards)
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Identifying adeno-associated viruses to successfully and specifically target human glia
Diaz-Castro, B. (Principal Investigator), Durrant, C. (Co-investigator), Hasel, P. (Co-investigator), Thangaraj Selvaraj, B. (Co-investigator) & Williams, A. (Co-investigator)
UK Dementia Research Institute Ltd
6/01/25 → 5/12/26
Project: Research
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Targeting Synaptic ingestion by astrocytes in Alzheimer’s disease
Spires-Jones, T. (Principal Investigator) & Durrant, C. (Co-investigator)
UK Dementia Research Institute Ltd
1/05/24 → 30/04/26
Project: Research
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Understanding and preventing synaptic spread of tau
Spires-Jones, T. (Principal Investigator), Diaz-Castro, B. (Co-investigator) & Durrant, C. (Co-investigator)
1/03/24 → 31/08/27
Project: Research
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Mechanisms of tau pathology progression in primary tauopathy
Durrant, C. (Principal Investigator) & Spires-Jones, T. (Co-investigator)
1/07/22 → 30/09/26
Project: Research
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Mechanisms of tau pathology progression in primary tauopathy
Durrant, C. (Principal Investigator) & Spires-Jones, T. (Co-investigator)
1/07/22 → 30/06/25
Project: Research
Datasets
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p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003
Durrant, C. (Creator), Taylor, L. (Creator) & Spires-Jones, T. (Creator), Edinburgh DataShare, 8 Feb 2024
DOI: 10.7488/ds/7680, https://doi.org/10.1007/s00401-023-02667-w
Dataset
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Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures
Tulloch, J. (Creator), Rose, J. (Creator), Gobbo, F. (Creator), Chang, Y. Y. (Creator), McLay, L. (Creator), King, D. (Creator), Liaquat, I. (Creator), Spires-Jones, T. (Creator), Booker, S. (Creator), Brennan, P. (Creator), Durrant, C. (Creator), Elliott, J. (Creator), Mcgeachan, R. (Creator), Meftah, S. (Creator), Taylor, L. (Creator), Catterson, J. (Creator), Negro, D. (Creator), Bonthron, C. (Creator) & Holt, K. (Creator), Edinburgh DataShare, 7 Apr 2025
DOI: 10.7488/ds/7890
Dataset
Press/Media
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Sophie visits dementia research lab founded by F1 champion Sir Jackie Stewart
1/04/25
1 Media contribution
Press/Media: Research
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Alzheimer's cure hope as man, 70, could be 'resistant' to killer disease
18/02/25
1 Media contribution
Press/Media: Research
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'Doctors think I'm resistant to Alzheimer's in my 70s - findings could change world'
18/02/25
1 Media contribution
Press/Media: Research
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Dementia doctor reveals the four huge things you could be doing to stave off Alzheimer's
7/07/21
1 item of Media coverage
Press/Media: Expert Comment
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Dr Claire Durrant: Locked-out of the lab: time to think?
29/07/20
1 Media contribution
Press/Media: Research