Colin Sharp

Colin Sharp

DR

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Personal profile

Research Interests

The primary research interest of my group is in the discovery and characterisation of new and emerging viruses. Our recent work has involved the discovered of novel small DNA viruses in wild rodents, which we are currently using as models for the investigation of anellovirus pathogenesis and evolution.

There have been huge advances in the field of DNA sequencing in recent years and we aim to use these newly available technologies to identify new viral species in both humans and animals. 

Many newly discovered viral infections appear to be present in high proportions of the population while causing no apparent disease.  Ongoing projects in my lab are addressing a number of the questions raised by the presence of these infections including:

-What types of subclinical viral infections can be found in animals, including those of agricultural importance?

-At what level are these viral infections present in the population and how are they transmitted?

-What role do these infections have during unexplained illnesses, production losses, co-infections and autoimmune disease processes?

The ultimate aim of these investigations is to determine the disease burden represented by these agents and whether intervention strategies could be used to improve the overall health of the animals or human patients.  In addition, study of these viruses will provide important fundamental information on viral biology, evolution and transmission.

My research in a nutshell

Colin’s main research interest is in the discovery and characterisation of new and emerging viruses. In order to investigate this, Colin has developed new techniques, and looked at diseases associated with these viruses and their possible transmission between animals and humans.

Education/Academic qualification

Virology, Doctor of Philosophy (PhD), University of Edinburgh

20022006

(Upper second class: Honours) in Immunology, Bachelor of Science, University of Glasgow

19962000

External positions

Senior Postdoctoral Post working with Prof. Peter Simmonds, 'Serological Detection of Exposure to the Parvovirus, PARV4', 'Impact of Recently Discovered Human Polyomavirus', 'Investigation of a Viral Aetiology for Scrapie and Other TSEs', University of Edinburgh, Centre for Infectious Diseases

20062010

PhD Project, 'The Molecular Basis of Malignant Catarrhal Fever', University of Edinburgh, Division of Veterinary Biomedical Sciences

20022006

Research Trainee, 'Murine Autoimmune Oophoritis as a Model Autoimmune Disease', University of Virginia, Department of Pathology

20002002

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