Damian Mole – Projects — University of Edinburgh Research Explorer

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4 Active
14 Finished

18 results

Active

Kynurenine-3-monooxygenase (KMO) inhibition as a novel therapeutic strategy to enhance islet cell viability and improve outcomes of Islet Cell Transplantation
Mole, D.
MRC
1/12/21 → 30/11/24
Project: Research
Does impaired adipose tissue B cell function lead to loss of natural antibody secretion and increase susceptibility to infection in obesity?
Mole, D.
EPSRC
1/01/21 → 31/12/24
Project: Research
Defining the mechanistic role of Kynurenine-3-monooxygenase in breast cancer
Mole, D., Mackay, L., Serrels, A. & Sims, A.
UK central government bodies/local authorities, health and hospital authorities
1/08/19 → 31/07/23
Project: Research
Premature death and organ hypofunction after severe acute pancreatitis results from cellular senescence - mechanisms and new opportunities for therapy
Mole, D.
MRC
1/02/17 → 31/01/23
Project: Research
Finished
Enabling soft surgical robots with precision proprioception
Yang, Y., Giorgio-Serchi, F. & Mole, D.
1/12/21 → 31/08/22
Project: Research
Kynurenine monooxygenase (KMO) inhibition as a novel therapy for endometriosis: proof-of-concept
Mole, D. & Saunders, P.
MRC
1/02/21 → 30/06/22
Project: Research
Single cell definition of the mechanistic role of kynurenine monooxygenase at the innate immune interface in acute pancreatitis.
Mole, D., Ramachandran, P. & Yao, C.
UK-based charities
7/08/19 → 6/08/22
Project: Research
KMO-PET: A radiotracer against kynurenine-3-monooxygenase for positron emission tomography imaging in cancer and endometriosis
Mole, D., Horne, A., Saunders, P. & Serrels, A.
MRC
1/02/19 → 31/10/19
Project: Research
APPreSci Consortium - Acute Pancreatitis Precison Science - Consortium Building Award
Mole, D.
MRC
1/03/17 → 30/11/17
Project: Research
Hepatica: Quantifying liver health in surgical candidates for liver malignancies
Mole, D., Fallowfield, J., Garden, J., Kendall, T., Kendall, T., Semple, S. & Wigmore, S.
UK central government bodies/local authorities, health and hospital authorities
1/02/17 → 31/03/19
Project: Research
Diagnosis, treatment, palliation and prevention of acute inflammatory disorders
Mole, D.
UK industry, commerce and public corporations
25/11/16 → 24/11/17
Project: Research
Quantitative and anatomical definition of kynurenine metabolism in rodents during systemic inflammation.
Mole, D.
UK-based charities
1/09/16 → 31/08/17
Project: Research
eHealth Integration of Multidiciplinary Cancer Care in Scotland
Mole, D.
UK central government bodies/local authorities, health and hospital authorities
1/06/16 → 31/08/16
Project: Research
Defining the mechanistic role of kynurenine-3-monooxygenase (KMO) inhibition in the resolution of severe acute pancreatitis organ dysfunction: Fellowship for Alistair Hayes
Hayes, A., Garden, J., Iredale, J. & Mole, D.
UK-based charities
1/08/14 → 31/07/17
Project: Research
Inflammation, Metabolism and Organ Failure in Acute Pancreatitis
Mole, D.
UK industry, commerce and public corporations
1/08/13 → 30/06/14
Project: Research
THE ROLE OF KMO INHIBITORS
Webster, S. & Mole, D.
UK industry, commerce and public corporations
1/11/11 → 31/12/17
Project: Research
Functional Optical Imagingin Mouse and Man
Mole, D., Auer, M., Bradley, M., Dhaliwal, K., Harrison, E., Haslett, C., Mowat, C., Simpson, J., Walkinshaw, M. & Wigmore, S.
MRC
1/10/09 → 31/03/12
Project: Research
Preventing acute lung injury by therapeutic targeting of the kynurenine pathway of tryptophan metabolism
Mole, D.
UK-based charities
1/02/08 → 31/01/09
Project: Research