Daniel Smith

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Daniel Smith

PROF

 https://orcid.org/0000-0002-2267-1951

Accepting PhD Students

Personal profile

Biography

Professor Smith is Chair of Psychiatry and Head of the Division of Psychiatry within the Centre for Clinical Brain Sciences. He also works as an Honorary Consualtant Psychiatrist in NHS Lothian and is Convenor for Undergraduate Psychiatry witin Edinburgh Medical School.

He trained in medicine at the University of Edinburgh (BSc, 1994 and MB ChB, 1996) and completed a clinical research training fellowship in Edinburgh (MD, 2006) alongside an International Masters in Affective Neuroscience in Maastricht (MSc, 2006). After clinical training Prfoessor Smith held a postdoctoral fellowship from the National Institute of Health Research (NIHR) at Cardiff University (2006-2012). He moved to the University of Glasgow as Reader in Psychiatry in 2012 and was promoted to a personal chair in 2014. He joined the University of Edinburgh in April 2021.

Professor Smith's work has been recognised by a number of awards and fellowships, including the American Psychiatric Institute ‘Young Minds in Psychiatry’ International Award for Bipolar Disorder (2007), the Association of European Psychiatrists Research Prize (2007), an NIHR Postdoctoral Fellowship (2008-2011), an Independent Investigator Award from the Brain and Behaviour Research Foundation (2014), the British Medical Journal Innovation Team Award (2014), and a Lister Institute Prize Fellowship (2016).

Qualifications

BSc, MB ChB, MSc, MD, FRCPsych.

Websites

 

 

Current Research Interests

Professor Smith's research interests are in four main areas:

  • The genetic epidemiology of mood disorders (particularly bipolar disorder)
  • Data science and mental health informatics research
  • Understanding comorbidity between mental and physical health disorders
  • Sleep and circadian health as they relate to mood disorders

His group has been at the forefront of mental health research using data from the UK Biobank cohort and he is part of several global research collaborations, including the Psychiatric Genomics Consortium, the Consortium for Lithium Genomics and the Chronobiology Task Force of the International Society for Bipolar Disorder. 

Media

Mental Health Research Using UK Biobank Data

Schools-based Mental Health Research

Professor Daniel Smith on BBC World News - Bipolar Disorder

Sleep, Circadian Rhythms and Mental Health

BBC Scotland River City: Discussion on Bipolar Disorder Storyline

 

Keywords

  • RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
  • QH426 Genetics
  • R Medicine (General)
  • RA0421 Public health. Hygiene. Preventive Medicine

Research Themes and Networks

  • Edinburgh Mental Health Network

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Collaborations and top research areas from the last five years

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  • A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic and magnetic resonance spectroscopy findings

    Campbell, I. H., Needham, N., Grossi, H., Kamenska, I., Luz, S., Sheehan, S., Thompson, G., Thrippleton, M. J., Gibbs, M. C., Leitao, J., Moses, T., Burgess, K., Rigby, B. P., Simpson, S. A., McIntosh, E., Brown, R., Meadowcroft, B., Creasy, F., Mitchell-Grigorjeva, M. & Norrie, J. & 6 others, McLellan, A., Fisher, C., Zieliński, T., Gaggioni, G., Campbell, H. & Smith, D. J., 25 Feb 2025, In: BJPsych Open. 11, 2, 8 p., e34.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Depression and physical multimorbidity: A cohort study of physical health condition accrual in UK Biobank

    Fleetwood, K. J., Guthrie, B., Jackson, C. A., Kelly, P. A. T., Mercer, S. W., Morales, D. R., Norrie, J. D., Smith, D. J., Sudlow, C. & Prigge, R., 13 Feb 2025, In: PLoS Medicine. 22, 2, e1004532.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Co-production in sleep research: A scoping review of current practices and future directions

    Gale, E. L., Manrai, R., Caddick, L., Murray, A. L., Whalley, H., Smith, D. & Gardani, M., 9 Feb 2025, (E-pub ahead of print) In: Journal of sleep research. p. 1-19 19 p., e14476.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 6 Feb 2025, In: Cell. 188, 3, p. 640-652.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Genomics yields biological and phenotypic insights into bipolar disorder

    O’connell, K. S., Koromina, M., Van der veen, T., Boltz, T., David, F. S., Yang, J. M. K., Lin, K.-H., Wang, X., Coleman, J. R. I., Mitchell, B. L., Mcgrouther, C. C., Rangan, A. V., Lind, P. A., Koch, E., Harder, A., Parker, N., Bendl, J., Adorjan, K., Agerbo, E. & Albani, D. & 290 others, Alemany, S., Alliey-Rodriguez, N., Als, T. D., Andlauer, T. F. M., Antoniou, A., Ask, H., Bass, N., Bauer, M., Beins, E. C., Bigdeli, T. B., Pedersen, C. B., Boks, M. P., Børte, S., Bosch, R., Brum, M., Brumpton, B. M., Brunkhorst-Kanaan, N., Budde, M., Bybjerg-Grauholm, J., Byerley, W., Cabana-Domínguez, J., Cairns, M. J., Carpiniello, B., Casas, M., Cervantes, P., Chatzinakos, C., Chen, H.-C., Clarence, T., Clarke, T.-K., Claus, I., Coombes, B., Corfield, E. C., Cruceanu, C., Cuellar-Barboza, A., Czerski, P. M., Dafnas, K., Dale, A. M., Dalkner, N., Degenhardt, F., Depaulo, J. R., Djurovic, S., Drange, O. K., Escott-Price, V., Fanous, A. H., Fellendorf, F. T., Ferrier, I. N., Forty, L., Frank, J., Frei, O., Freimer, N. B., Fullard, J. F., Garnham, J., Gizer, I. R., Gordon, S. D., Gordon-Smith, K., Greenwood, T. A., Grove, J., Guzman-Parra, J., Ha, T. H., Hahn, T., Haraldsson, M., Hautzinger, M., Havdahl, A., Heilbronner, U., Hellgren, D., Herms, S., Hickie, I. B., Hoffmann, P., Holmans, P. A., Huang, M.-C., Ikeda, M., Jamain, S., Johnson, J. S., Jonsson, L., Kalman, J. L., Kamatani, Y., Kennedy, J. L., Kim, E., Kim, J., Kittel-Schneider, S., Knowles, J. A., Kogevinas, M., Kranz, T. M., Krebs, K., Kushner, S. A., Lavebratt, C., Lawrence, J., Leber, M., Lee, H.-J., Liao, C., Lucae, S., Lundberg, M., Macintyre, D. J., Maier, W., Maihofer, A. X., Malaspina, D., Manchia, M., Maratou, E., Martinsson, L., Mattheisen, M., Mcgregor, N. W., Mcinnis, M. G., Mckay, J. D., Medeiros, H., Meyer-Lindenberg, A., Millischer, V., Morris, D. W., Moutsatsou, P., Mühleisen, T. W., O’donovan, C., Olsen, C. M., Panagiotaropoulou, G., Papiol, S., Pardiñas, A. F., Park, H. Y., Perry, A., Pfennig, A., Pisanu, C., Potash, J. B., Quested, D., Regeer, E. J., Rice, J. P., Rivera, M., Schulte, E. C., Senner, F., Shadrin, A., Shilling, P. D., Sigurdsson, E., Sindermann, L., Sirignano, L., Siskind, D., Slaney, C., Sloofman, L. G., Smeland, O. B., Smith, D. J., Sobell, J. L., Soler artigas, M., Stein, D. J., Stein, F., Su, M.-H., Sung, H., Świątkowska, B., Terao, C., Tesfaye, M., Tesli, M., Thorgeirsson, T. E., Thorp, J. G., Toma, C., Tondo, L., Tooney, P. A., Tsai, S.-J., Tsermpini, E. E., Vawter, M. P., Vedder, H., Vreeker, A., Walters, J. T. R., Winsvold, B. S., Witt, S. H., Won, H.-H., Ye, R., Zandi, P. P., Young, A. H., Zillich, L., 23andMe Research Team, Estonian Biobank Research Team, Genoplan Research Team, HUNT All-In Psychiatry, PGC-FG Single cell working group, Genomic Psychiatry Cohort (GPC) Investigators, Cooperative Studies Program (CSP) #572, Million Veteran Program (MVP), Adolfsson, R., Alda, M., Alfredsson, L., Backlund, L., Baune, B. T., Bellivier, F., Bengesser, S., Berrettini, W. H., Biernacka, J. M., Boehnke, M., Børglum, A. D., Breen, G., Carr, V. J., Catts, S., Cichon, S., Corvin, A., Craddock, N., Dannlowski, U., Dikeos, D., Etain, B., Ferentinos, P., Frye, M., Fullerton, J. M., Gawlik, M., Gershon, E. S., Goes, F. S., Green, M. J., Grigoroiu-Serbanescu, M., Hauser, J., Henskens, F. A., Hjerling-Leffler, J., Hougaard, D. M., Hveem, K., Iwata, N., Jones, I., Jones, L. A., Kahn, R. S., Kelsoe, J. R., Kircher, T., Kirov, G., Kuo, P.-H., Landén, M., Leboyer, M., Li, Q. S., Lissowska, J., Lochner, C., Loughland, C., Luykx, J. J., Martin, N. G., Mathews, C. A., Mayoral, F., Mcelroy, S. L., Mcintosh, A. M., Mcmahon, F. J., Medland, S. E., Melle, I., Mitchell, P. B., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Myers, R. M., Myung, W., Neale, B. M., Nievergelt, C. M., Nordentoft, M., Nöthen, M. M., Nurnberger, J. I., O’donovan, M. C., Oedegaard, K. J., Olsson, T., Owen, M. J., Paciga, S. A., Pantelis, C., Pato, C. N., Pato, M. T., Patrinos, G. P., Pawlak, J. M., Ramos-Quiroga, J. A., Reif, A., Reininghaus, E. Z., Ribasés, M., Rietschel, M., Ripke, S., Rouleau, G. A., Roussos, P., Saito, T., Schall, U., Schalling, M., Schofield, P. R., Schulze, T. G., Scott, L. J., Scott, R. J., Serretti, A., Smoller, J. W., Squassina, A., Stahl, E. A., Stefansson, H., Stefansson, K., Stordal, E., Streit, F., Sullivan, P. F., Turecki, G., Vaaler, A. E., Vieta, E., Vincent, J. B., Waldman, I. D., Weickert, C. S., Weickert, T. W., Werge, T., Whiteman, D. C., Zwart, J.-A., Edenberg, H. J., Mcquillin, A., Forstner, A. J., Mullins, N., Di florio, A., Ophoff, R. A., Andreassen, O. A. & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 22 Jan 2025, In: Nature.

    Research output: Contribution to journal › Article › peer-review

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  • 1 Public Engagement – Public lecture/debate/seminar
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