David Gally

2016

Short term evolution of Shiga toxin producing Escherichia coli O157:H7 between two food-borne outbreaks

Cowley, L. A., Dallman, T. J., Fitzgerald, S., Irvine, N., Rooney, P. J., Mcateer, S. P., Day, M., Perry, N. T., Bono, J., Jenkins, C. & Gally, D. L., 9 Aug 2016, (E-pub ahead of print) In: Microbial Genomics.

Research output: Contribution to journal › Article › peer-review

Open Access

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Phylogenomic approaches to determine the zoonotic potential of Shiga toxin-producing Escherichia coli (STEC) isolated from Zambian dairy cattle

Mainda, G., Lupolova, N., Sikakwa, L., Bessell, P. R., Muma, J. B., Hoyle, D. V., McAteer, S. P., Gibbs, K., Williams, N. J., Sheppard, S. K., La Ragione, R. M., Cordoni, G., Argyle, S. A., Wagner, S., Chase-Topping, M. E., Dallman, T. J., Stevens, M. P., Bronsvoort, M. & Gally, D. L., 25 May 2016, (E-pub ahead of print) In: Scientific Reports. 6, 26589.

Research output: Contribution to journal › Article › peer-review

Open Access

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Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

De Majumdar, S., Yu, J., Fookes, M., Mcateer, S. P., Llobet, E., Spence, S. F. S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., 11 May 2016, In: PLoS Pathogens. 12, 5, e1005649.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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Type III Secretion-Dependent Sensitivity of Escherichia coli O157 to Specific Ketolides

Fernandez-brando, R., Yamaguchi, N., Tahoun, A., Mcateer, S. P., Gillespie, T., Wang, D., Argyle, S. A., Palermo, M. S. & Gally, D. L., Jan 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 459–470

Research output: Contribution to journal › Article › peer-review

Open Access

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2015

Immunogenic compositions containing Escherichia coli H7 flagella and methods of use thereof

Gally, D., McNeilly, T. N., Emslie Smith, D. G., Low, J., Kumar, A. & Naylor, S. W., 24 Nov 2015, Patent No. US 9193770 B2, Priority date 17 Oct 2007

Research output: Patent

Molecular characterisation and phylogenetics of Shiga toxin producing Escherichia coli (STEC) isolated from Zambian dairy cattle.

Mainda, G., Lupolova, N., Muma, J., Bronsvoort, M., Stevens, M. & Gally, D., Oct 2015.

Research output: Contribution to conference › Paper

Erratum: Prevalence and patterns of antimicrobial resistance among Escherichia coli isolated from Zambian dairy cattle across different production systems (Scientific Reports (2015) 5 (12439) DOI: 10.1038/srep12439)

Mainda, G., Bessell, P. R., Muma, J. B., McAteer, S. P., Chase-Topping, M. E., Gibbons, J., Stevens, M. P., Gally, D. L. & Bronsvoort, M., 21 Sept 2015, In: Scientific Reports. 5, 14162.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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Applying phylogenomics to understand the emergence of Shiga Toxin producing Escherichia coli O157:H7 strains causing severe human disease in the United Kingdom.

Holmes, A., Jenkins, C., Hanson, M., Woolhouse, M., Wain, J., Allison, L., Chase-topping, M., Gally, D., Gunn, G., Ellis, R., Grant, K., Petrovska, L., Perry, N., Byrne, L., Ashton, P. & Dallman, T., 14 Sept 2015, In: Microbial Genomics.

Research output: Contribution to journal › Article › peer-review

Open Access

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Cellular immunity to Enterohaemorrhagic Escherichia coli O157 in cattle and implications for vaccine development

McNeilly, T. N., Corbishley, A., Connelley, T. & Gally, D., Sept 2015.

Research output: Contribution to conference › Poster › peer-review

Prevalence and patterns of antimicrobial resistance among Escherichia coli isolated from Zambian dairy cattle across different production systems

Mainda, G., Bessell, P., Muma, J., McAteer, S., Chase-Topping, M., Gibbons, J., Stevens, M., Gally, D. & Bronsvoort, M., 27 Jul 2015, In: Scientific Reports. 5, 12439.

Research output: Contribution to journal › Article › peer-review

Open Access

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Cellular immune responses in cattle colonised with Escherichia coli O157:H7

Corbishley, A., Gally, D. & McNeilly, T. N., 10 Jul 2015, p. 34. 1 p.

Research output: Contribution to conference › Abstract

Optimizing the Protection of Cattle against Escherichia coli O157: H7 Colonization through Immunization with Different Combinations of H7 Flagellin, Tir, Intimin-531 or EspA

McNeilly, T. N., Mitchell, M. C., Corbishley, A., Nath, M., Simmonds, H., McAteer, S. P., Mahajan, A., Low, J. C., Smith, D. G. E., Huntley, J. F. & Gally, D. L., 28 May 2015, In: PLoS ONE. 10, 5, 19 p., 0128391.

Research output: Contribution to journal › Article › peer-review

Open Access

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Analysis of whole genome sequencing for the Escherichia coli O157:H7 typing phages

Cowley, L. A., Beckett, S. J., Chase-Topping, M., Perry, N., Dallman, T. J., Gally, D. L. & Jenkins, C., 8 Apr 2015, In: BMC Genomics. 16, 271.

Research output: Contribution to journal › Article › peer-review

Open Access

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Functional analysis of bovine TLR5 and association with IgA responses of cattle following systemic immunisation with H7 flagella

Tahoun, A., Jensen, K., Corripio-Miyar, Y., McAteer, S. P., Corbishley, A., Mahajan, A., Brown, H., Frew, D., Aumeunier, A., Smith, D. G. E., McNeilly, T. N., Glass, E. J. & Gally, D. L., 19 Feb 2015, In: Veterinary Research. 46, 1, 9.

Research output: Contribution to journal › Article › peer-review

Open Access

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Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

De Majumdar, S., Yu, J., Fookes, M., Mcateer, S. P., Llobet, E., Finn, S., Spence, S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T., 29 Jan 2015, In: PLoS Pathogens. 11, 1, p. e1004627 22 p., 1004627.

Research output: Contribution to journal › Article › peer-review

Open Access

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Bacterial Flagella: Twist and Stick, or Dodge across the Kingdoms

Rossez, Y., Wolfson, E. B., Holmes, A., Gally, D. L. & Holden, N. J., 15 Jan 2015, In: PLoS Pathogens. 11, 1, p. e1004483

Research output: Contribution to journal › Article › peer-review

Open Access

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2014

Strain dependent cellular immune responses in cattle following Escherichia coli O157:H7 colonisation

Corbishley, A., Ahmad, N. I., Hughes, K., Hutchings, M. R., McAteer, S. P., Connelley, T. K., Brown, H., Gally, D. L. & McNeilly, T. N., 29 Sept 2014, In: Infection and Immunity. 82, 12, p. 5117-5131

Research output: Contribution to journal › Article › peer-review

Identification of bacteriophage-encoded anti-sRNAs in pathogenic escherichia coli

Tree, J. J., Granneman, S., McAteer, S. P., Tollervey, D. & Gally, D. L., 17 Jul 2014, In: Molecular Cell. 55, 2, p. 199-213 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7

Beckham, K. S. H., Connolly, J. P. R., Ritchie, J. M., Wang, D., Gawthorne, J. A., Tahoun, A., Gally, D. L., Burgess, K., Burchmore, R. J., Smith, B. O., Beatson, S. A., Byron, O., Wolfe, A. J., Douce, G. R. & Roe, A. J., 21 May 2014, In: Molecular Microbiology. 93, 1, p. 199-211 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Multidrug-resistant Escherichia coli from canine urinary tract infections tend to have commensal phylotypes, lower prevalence of virulence determinants and ampC-replicons

Wagner, S., Gally, D. L. & Argyle, S. A., 14 Mar 2014, In: Veterinary Microbiology. 169, 3-4, p. 171-178

Research output: Contribution to journal › Article › peer-review

Open Access

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Identification and characterization of a peculiar vtx2-converting phage frequently present in verocytotoxin-producing Escherichia coli O157 isolated from human infections

Tozzoli, R., Grande, L., Michelacci, V., Fioravanti, R., Gally, D., Xu, X., Ragione, R. L., Anjum, M., Wu, G., Caprioli, A. & Morabito, S., 1 Jan 2014, In: Infection and Immunity. 82, 7, p. 3023-3032 10 p.

Research output: Contribution to journal › Article › peer-review

Detection of resistance and virulence-associated genes in E. coli isolated from Zambian dairy cattle

Mainda, G., Stevens, M., Bronsvoort, M. & Gally, D., 2014.

Research output: Contribution to conference › Poster

Flagella interact with ionic plant lipids to mediate adherence of pathogenic Escherichia coli to fresh produce plants

Rossez, Y., Holmes, A., Wolfson, E. B., Gally, D. L., Mahajan, A., Pedersen, H. L., Willats, W. G. T., Toth, I. K. & Holden, N. J., 2014, In: Environmental Microbiology. 16, 7, p. 2181-2195

Research output: Contribution to journal › Article › peer-review

2013

Predicting the public health benefit of vaccinating cattle against Escherichia coli O157

Matthews, L., Reeve, R., Gally, D. L., Low, C., Woolhouse, M. E. J., McAteer, S. P., Locking, M. E., Chase-Topping, M. E., Haydon, D. T., Allison, L. J., Hanson, M., Gunn, G. J. & Reid, S. W. J., 1 Oct 2013, In: Proceedings of the National Academy of Sciences (PNAS). 110, 40, p. 16265-16270 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Immune responses of cattle to Escherichia coli O157:H7 colonisation

Corbishley, A., Gally, D. & McNeilly, T., Oct 2013, In: Cattle Practice. 21, 2, p. 160-160 1 p.

Research output: Contribution to journal › Editorial › peer-review

Bacteriophages as pathogens and immune modulators?

Lengeling, A., Mahajan, A. & Gally, D. L., 2013, In: mBio. 4, 6, e00868-13.

Research output: Contribution to journal › Editorial › peer-review

Open Access

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2012

A novel adjuvant system based on insoluble H7 flagellin containing microparticles induces enhanced humoral immune responses in Quil A-adjuvanted vaccines

McNeilly, T. N., Frew, D., Bartley, Y., Aumeunier, A., Lyle, C., Mahajan, A., Smith, D. G. E., Gally, D. L., Vos, J. & Moore, B. D., Sept 2012, In: Immunology . 137, Suppt. S1, p. 753-753 1 p., Abstract P1855.

Research output: Contribution to journal › Meeting abstract › peer-review

Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion

Flockhart, A. F., Tree, J. J., Xu, X., Karpiyevich, M., McAteer, S. P., Rosenblum, R., Shaw, D. J., Low, C. J., Best, A., Gannon, V., Laing, C., Murphy, K. C., Leong, J. M., Schneiders, T., La Ragione, R. & Gally, D. L., 2012, In: Molecular Microbiology. 83, 1, p. 208-223

Research output: Contribution to journal › Article › peer-review

Open Access

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Insights into mucosal innate responses to Escherichia coli O157: H7 colonization of cattle by mathematical modelling of excretion dynamics

Tildesley, M., Gally, D., McNeilly, T. N., Low, C., Mahajan, A. & Savill, N., 2012, In: Journal of the Royal Society. Interface. 9, 68, p. 518-527 10 p.

Research output: Contribution to journal › Article › peer-review

Lysogeny with Shiga Toxin 2-Encoding Bacteriophages Represses Type III Secretion in Enterohemorrhagic Escherichia coli

Xu, X., McAteer, S. P., Tree, J. J., Shaw, D. J., Wolfson, E. B. K., Beatson, S. A., Roe, A. J., Allison, L. J., Chase-Topping, M. E., Mahajan, A., Tozzoli, R., Woolhouse, M. E. J., Morabito, S. & Gally, D. L., 2012, In: PLoS Pathogens. 8, 5, e1002672.

Research output: Contribution to journal › Article › peer-review

Open Access

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Pathogenic Potential to Humans of Bovine Escherichia coli O26, Scotland

Chase-Topping, M. E., Rosser, T., Allison, L. J., Courcier, E., Evans, J., McKendrick, I. J., Pearce, M. C., Handel, I., Caprioli, A., Karch, H., Hanson, M., Pollock, K. G., Locking, M. E., Woolhouse, M. E., Matthews, L., Low, J. C. & Gally, D. L., 2012, In: Emerging Infectious Diseases. 18, 3, p. 439-448 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Salmonella transforms follicle-associated epithelial cells into M cells to promote intestinal invasion

Tahoun, A., Mahajan, S., Paxton, E., Malterer, G., Donaldson, D. S., Wang, D., Tan, A., Gillespie, T. L., O'Shea, M., Roe, A. J., Shaw, D. J., Gally, D. L., Lengeling, A., Mabbott, N. A., Haas, J. & Mahajan, A., 2012, In: Cell Host & Microbe. 12, 5, p. 645-56 12 p.

Research output: Contribution to journal › Article › peer-review

Using High Throughput Sequencing to Characterise Key Regulators of the Cold Shock Response.

McGibbon, L., Tree, J., Granneman, S., Woodall, K., Gally, D., Blakely, G., Tollervey, D. & Gallagher, M., 2012, p. 74.

Research output: Contribution to conference › Poster

2011

Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds

Wang, D., Zetterstrom, C. E., Gabrielsen, M., Beckham, K. S., Tree, J. J., Macdonald, S. E., Byron, O., Mitchell, T. J., Gally, D. L., Herzyk, P., Mahajan, A., Uvell, H., Burchmore, R., Smith, B. O., Elofsson, M. & Roe, A. J., 26 Aug 2011, In: Journal of Biological Chemistry. 286, 34, p. 29922-29931 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Transcriptional regulators of the GAD acid stress island are carried by effector protein-encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7

Tree, J. J., Roe, A. J., Flockhart, A., McAteer, S. P., Xu, X., Shaw, D., Mahajan, A., Beatson, S. A., Best, A., Lotz, S., Woodward, M. J., La Ragione, R., Murphy, K. C., Leong, J. M. & Gally, D. L., Jun 2011, In: Molecular Microbiology. 80, 5, p. 1349-1365 17 p.

Research output: Contribution to journal › Article › peer-review

File

Comparative analysis of EspF variants in inhibition of Escherichia coli phagocytosis by macrophages and inhibition of E. coli translocation through human- and bovine-derived M cells

Tahoun, A., Siszler, G., Spears, K., McAteer, S., Tree, J., Paxton, E., Gillespie, T. L., Martinez-Argudo, I., Jepson, M. A., Shaw, D. J., Koegl, M., Haas, J., Gally, D. L. & Mahajan, A., 2011, In: Infection and Immunity. 79, 11, p. 4716-29 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Escherichia coli and the mucosal immune system

Mahajan, A. & Gally, D., 2011, In: Expert Review of Clinical Immunology. 7, 6, p. 743-745 3 p.

Research output: Contribution to journal › Article › peer-review

In vivo targets of the cold shock proteins CspA and CspE

McGibbon, L., Tree, J., Woodall, K., Wlotzka, W., Granneman, S., Blakely, G., Gally, D., Tollervey, D. & Gallagher, M., 2011, p. 44.

Research output: Contribution to conference › Abstract

Molecular and functional characterization of the adherent properties of H7 flagella

Wolfson, E., Xue, X., Gally, D. & Mahajan, A., 2011, p. 63.

Research output: Contribution to conference › Abstract

Prophage regulation of enterohaemorrhagic Escherichia coli colonization in ruminants

Gally, D., 2011, p. 22.

Research output: Contribution to conference › Abstract

Screening of an E. coli O157:H7 bacterial artificial chromosome library by comparative genomic hybridisation to identify genomic regions contributing to growth in bovine gastrointestinal mucus and epithelial cell colonization

Bai, J., McAteer, S. P., Paxton, E., Mahajan, A., Gally, D. & Tree, J. J., 2011, In: Frontiers in Microbiology. 2, Article 168, 9 p., 168.

Research output: Contribution to journal › Article › peer-review

Open Access

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Screening of an E. coli O157:H7 Bacterial Artificial Chromosome Library by Comparative Genomic Hybridization to Identify Genomic Regions Contributing to Growth in Bovine Gastrointestinal Mucus and Epithelial Cell Colonization

Bai, J., Mcateer, S. P., Paxton, E., Mahajan, A., Gally, D. L. & Tree, J. J., 2011, In: Frontiers in Microbiology. 2

Research output: Contribution to journal › Article › peer-review

Open Access

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2010

Associations between the presence of virulence determinants and the epidemiology and ecology of zoonotic Escherichia coli

O'Reilly, K. M., Low, J. C., Denwood, M. J., Gally, D. L., Evans, J., Gunn, G. J., Mellor, D. J., Reid, S. W. & Matthews, L., Dec 2010, In: Applied and Environmental Microbiology. 76, 24, p. 8110-6 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof

Gally, D., Mahajan, A., Low, C., McNeilly, T. M. & Smith, D. G. E., 30 Jun 2010, Patent No. EP2201029 A1

Research output: Patent

IgA and IgG antibody responses following systemic immunization of cattle with native H7 flagellin differ in epitope recognition and capacity to neutralise TLR5 signalling

McNeilly, T. N., Mitchell, M. C., Nisbet, A. J., McAteer, S., Erridge, C., Inglis, N. F., Smith, D. G., Low, J. C., Gally, D. L., Huntley, J. F. & Mahajan, A., Feb 2010, In: Vaccine. 28, 5, p. 1412-21 10 p.

Research output: Contribution to journal › Article › peer-review

Immunization of cattle with a combination of purified intimin-531, EspA and Tir significantly reduces shedding of Escherichia coli O157:H7 following oral challenge

McNeilly, T. M., Mitchell, M. M., Rosser, T., McAteer, S., Low, J. C., Smith, D. G. E., Huntley, J. F., Mahajan, A. & Gally, D. L., Feb 2010, In: Vaccine. 28, 5, p. 1422-1428 7 p.

Research output: Contribution to journal › Article › peer-review