Research output per year
Research output per year
Personal profile
Education/Academic qualification
Doctor of Philosophy (PhD), A patch-clamp study of glutamate receptor channels and glutamate uptake in rat cerebellar neurones and glia, University of London
Award Date: 1 Jan 1992
Bachelor of Science, University of Glasgow
Award Date: 1 Jan 1988
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Dive into the research topics where David Wyllie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Better statistical reporting does not lead to statistical rigour: lessons from two decades of pseudoreplication in mouse-model studies of neurological disorders
Eleftheriou, C., Giachetti, S., Hickson, R., Kamnioti-Dumont, L., Templaar, R., Aaltonen, A., Tsoukala, E., Kim, N., Fryer-Petridis, L., Henley, C., Erdem, C., Wilson, E., Maio, B., Ye, J., Pierce, J. C., Mazur, K., Landa-Navarro, L., Petrović, N. G., Bendova, S. & Woods, H. & 17 others, , 26 May 2025, In: Molecular Autism. 16, 10 p., 30.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Absence of GluN2A in hippocampal CA1 neurons leads to altered dendritic structure and reduced frequency of miniature excitatory synaptic events
Yasmin, F., Marwick, K. F. M., Hunter, D. W., Nawaz, S., Marshall, G. F., Booker, S. A., Hardingham, G. E., Kind, P. C. & Wyllie, D. J. A., 26 Mar 2025, (E-pub ahead of print) In: Brain Communications. 7, 2, p. fcaf124Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
O'Keeffe, M., Booker, S. A., Walsh, D., Li, M., Henley, C., Simões De Oliveira, L., Liu, M., Wang, X., Banqueri Lopez, M., Ridley, K., Dissanayake, K., Martinez Gonzalez, C., Craigie, K. J., Vasoya, D., Leah, T., He, X., Hume, D. A., Duguid, I., Nolan, M. F. & Qiu, J. & 7 others, , 6 Jan 2025, In: Nature Neuroscience. p. 1-12Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Key roles of C2/GAP domains in SYNGAP1-related pathophysiology
Katsanevaki, D., Till, S. M., Buller-Peralta, I., Nawaz, M. S., Louros, S. R., Kapgal, V., Tiwari, S., Walsh, D., Anstey, N. J., Petrović, N. G., Cormack, A., Salazar-Sanchez, V., Harris, A., Farnworth-Rowson, W., Sutherland, A., Watson, T. C., Dimitrov, S., Jackson, A. D., Arkell, D. & Biswal, S. & 13 others, , 24 Sept 2024, In: Cell Reports. 43, 9, 114733.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder
Simões de Oliveira, L., O’Leary, H. E., Nawaz, S., Loureiro, R., Davenport, E. C., Baxter, P., Louros, S. R., Dando, O., Perkins, E., Peltier, J., Trost, M., Osterweil, E. K., Hardingham, G. E., Cousin, M. A., Chattarji, S., Booker, S. A., Benke, T. A., Wyllie, D. J. A. & Kind, P. C., 14 Jun 2024, In: Molecular Autism. 15, 1, 28.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Investigating NMDA Receptor Contributions to Postsynaptic Potentials, Synaptic Integration and Hippocampal Network Dynamics
Wyllie, D. (Principal Investigator)
1/06/25 → 31/05/27
Project: Research
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R-type calcium channel modulators in rodent models of Fragile X Syndrome
Wyllie, D. (Principal Investigator) & Kind, P. (Co-investigator)
UK industry, commerce and public corporations
9/08/21 → 18/10/21
Project: Research
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GluN2A haploinsufficiency: a novel pre-clinical model of epilepsy
Wyllie, D. (Principal Investigator), Hardingham, G. (Co-investigator), Kind, P. (Co-investigator) & Marwick, K. (Co-investigator)
13/03/17 → 30/09/19
Project: Research
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The role of the GluN2A NMDAR subunit in determining synaptic function and plasticity
Wyllie, D. (Principal Investigator), Hardingham, G. (Co-investigator), Kind, P. (Co-investigator) & Wood, E. (Co-investigator)
1/10/16 → 31/07/19
Project: Research
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MICA: Correction of behavioural, circuit and cellular deficits in rat models of ID/ASD
Kind, P. (Principal Investigator), Wood, E. (Co-investigator) & Wyllie, D. (Co-investigator)
1/09/16 → 28/02/21
Project: Research