Research output per year
Research output per year
Personal profile
Keywords
- TP Chemical technology
- QH301 Biology
- QD Chemistry
- RM Therapeutics. Pharmacology
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Dive into the research topics where Douglas Houston is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 41 Article
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A 5-FU precursor designed to evade anabolic and catabolic drug pathways and activated by Pd chemistry in vitro and in vivo
Adam, C., Bray, T., Perez-Lopez, A., Tan, E. H., Rubio Ruiz, B., Baillache, D., Houston, D. R., Salji, M. J., Leung, H. Y. & Unciti-Broceta, A., 3 Jan 2022, (E-pub ahead of print) In: Journal of Medicinal Chemistry.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Modelling of Hepatitis E virus RNA-dependent RNA polymerase genotype 3 from a chronic patient and in silico interaction analysis by molecular docking with Ribavirin
Cancela, F., Rendon Marin, S., Quintero-Gil, C., Houston, D. R., Gumbis, G., Panzera, Y., Arbiza, J., Mirazo, S. & Pérez, R., 3 Dec 2021, (E-pub ahead of print) In: Journal of Biomolecular Structure and Dynamics.Research output: Contribution to journal › Article › peer-review
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Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme
Harding, C. J., Sutherland, E., Hanna, J. G., Houston, D. R. & Czekster, C. M., 15 Jan 2021, (E-pub ahead of print) In: RSC Chemical Biology. 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
PRL3-DDX21 transcriptional control of endolysosomal genes restricts melanocyte stem cell differentiation
Johansson, J., Marie, K. L., Lu, Y., Brombin, A., Santoriello, C., Zeng, Z., Zich, J., Gautier, P., von Kriegsheim, A., Brunsdon, H., Wheeler, A. P., Dreger, M., Houston, D. R., Dooley, C. M., Sims, A. H., Busch-Nentwich, E. M., Zon, L. I., Illingworth, R. & Patton, E. E., 10 Aug 2020, In: Developmental Cell. 54, 3, p. 317-332.E9 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Recognition dynamics of cancer mutations on the ERp57-Tapasin interface
Padariya, M., Kalathiya, U., Houston, D. R. & Alfaro, J. A., 20 Mar 2020, In: Cancers. 12, 3, 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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The utility of consensus approaches in virtual drug discovery
Douglas Houston (Invited speaker)
28 Nov 2019Activity: Academic talk or presentation types › Invited talk
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Modelling approaches for rational solvent selection in drug development
Douglas Houston (Examiner)
19 Dec 2019Activity: Examination types › External Examiner or Assessor
Datasets
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Lamin A conformation modelling
Spanos, C. (Creator), Cardenal Peralta, C. (Creator), Schirmer, E. (Creator), Makarov, A. (Creator), Solovyova, A. S. (Creator), Houston, D. (Creator), Rappsilber, J. (Creator) & Zou, J. (Creator), Edinburgh DataShare, 1 Nov 2019
DOI: 10.7488/ds/2556
Dataset
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Mix and Match: Mono-substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity
McWhinnie, F. (Creator), Sepp, K. (Creator), Kunath, T. (Creator), Houston, D. (Creator), Hupp, T. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 22 Dec 2017
DOI: 10.7488/ds/2276
Dataset
Press / Media
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Edinburgh University launches new online masters in next generation drug discovery
Malcolm Walkinshaw, Douglas Houston & Paul Taylor
11/07/12
1 item of Media coverage
Press/Media: Research