Fiona Semple – Research output — University of Edinburgh Research Explorer

7 Article
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2021
Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome
Deciphering Developmental Disorders Study, 1 Oct 2021, In: Genome Research.
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2020
Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose
Laurent, D., Semple, F., Starkey Lewis, P. J., Rose, E., Black, H. A., Coe, J., Forbes, S. J., Arends, M. J., Dear, J. W. & Aitman, T. J., 6 Apr 2020, In: Journal Title BMC Medical Genomics. 13, 60 (2020).
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2017
Human β-defensin 3 increases the TLR9-dependent response to bacterial DNA
Mcglasson, S. L., Semple, F., Macpherson, H., Gray, M., Davidson, D. J. & Dorin, J. R., 7 Apr 2017, In: European Journal of Immunology. 47, 4
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2015
Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid
Semple, F., MacPherson, H., Webb, S., Kilanowski, F., Lettice, L., McGlasson, S. L., Wheeler, A. P., Chen, V., Millhauser, G. L., Melrose, L., Davidson, D. J. & Dorin, J. R., 8 Dec 2015, In: PLoS Genetics. 11, 12, e1005673.
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2013
Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
Zhou, Y., Webb, S., Lettice, L., Tardif, S., Kilanowski, F., Tyrrell, C., MacPherson, H., Semple, F., Tennant, P., Baker, T., Hart, A., Devenney, P. S., Perry, P., Davey, T., Barran, P., Barratt, C. L. R. & Dorin, J., Oct 2013, In: PLoS Genetics. 9, 10, e1003826.
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2012
β-Defensins: multifunctional modulators of infection, inflammation and more?
Semple, F. & Dorin, J. R., 2012, In: Journal of Innate Immunity. 4, 4, p. 337-48 12 p.
Research output: Contribution to journal › Article › peer-review
2011
Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF
Semple, F., MacPherson, H., Webb, S., Cox, S. L., Mallin, L. J., Tyrrell, C., Grimes, G. R., Semple, C. A., Nix, M. A., Millhauser, G. L. & Dorin, J. R., 2011, In: European Journal of Immunology. 41, 11, p. 3291-300 10 p.
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