Gina Cranswick

Search results

• 2020

  Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

  De Angelis, F., Connick, P., Parker, R. A., Plantone, D., Doshi, A., John, N., Stutters, J., Macmanus, D., Prados, F., Marshall, I., Solanky, B., Samson, R. S., Barkhof, F., Ourselin, S., Braisher, M., Ross, M., Cranswick, G., Pavitt, S. H., Gnanapavan, S., Giovannoni, G. & 8 others, Wheeler-kingshott, C. A. G., Hawkins, C., Sharrack, B., Bastow, R., Weir, C. J., Stallard, N., Chandran, S. & Chataway, J., 1 May 2020, In: Efficacy and Mechanism Evaluation. 7, 3, p. 1-72

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Riluzole 100%
  • Chronic Progressive Multiple Sclerosis 92%
  • Amiloride 81%
  • Fluoxetine 78%
  • Placebos 46%

• Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial

  MS -SMART Investigators, Chataway, J., De Angelis, F., Connick, P., Parker, R. A., Plantone, D., Doshi, A., John, N., Stutters, J., Macmanus, D., Prados Carrasco, F., Barkhof, F., Ourselin, S., Braisher, M., Ross, M., Cranswick, G., Pavitt, S. H., Giovannoni, G., Gandini Wheeler-kingshott, C. A., Hawkins, C. & 5 others, Sharrack, B., Bastow, R., Weir, C. J., Stallard, N. & Chandran, S., 1 Mar 2020, In: The Lancet Neurology. 19, 3, p. 214-225

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Progressive Multiple Sclerosis 100%
  • Neuroprotective Agents 73%
  • Riluzole 53%
  • Placebos 50%
  • Randomized Controlled Trials 48%
• 2018

  Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART). a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis

  The UK Multiple Sclerosis Society Clinical Trials Network, Connick, P., De Angelis, F., Parker, R., Plantone, D., Doshi, A., John, N., Stutters, J., MacManus, D., Prados Carrasco, F., Barkhof, F., Ourselin, S., Braisher, M., Ross, M., Cranswick, G. & Weir, C., 30 Aug 2018, In: BMJ Open.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Progressive Multiple Sclerosis 100%
  • Controlled Clinical Trials 79%
  • Neuroprotective Agents 73%
  • Random Allocation 71%
  • Riluzole 53%
• 2015

  Establishing a journal club to promote professional development within a trials unit

  Strachan, F., Cranswick, G., Smith, L. & Tuck, C., 16 Nov 2015, In: Trials. 16, S2

  Research output: Contribution to journal › Article

  Open Access
• 2013

  The Effect of Graduated Compression Stockings on Long-term Outcomes After Stroke The CLOTS Trials 1 and 2: the CLOTS trials 1 and 2

  Dennis, M., Sandercock, P., Reid, J., Graham, C., Murray, G., Venables, G., Rudd, A., Bowler, G., CLOTS Trials Collaboration & Cranswick, G., Apr 2013, In: Stroke. 44, 4, p. 1075-1079 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Compression Stockings 100%
  • Venous Thromboembolism 56%
  • Thigh 56%
  • Stroke 47%
  • Venous Thrombosis 33%
• 2010

  Thigh-Length Versus Below-Knee Stockings for Deep Venous Thrombosis Prophylaxis After Stroke: A Randomized Trial

  CLOTS Trial Collaborat, Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P., Reid, J., Murray, G., Venables, G., Rudd, A. & 10 others, Bowler, G., Celani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Ting, T., Baigent, C., Bamford, J. & Slattery, J., 2 Nov 2010, In: Annals of Internal Medicine. 153, 9, p. 553-562 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Venous Thrombosis 100%
  • Thigh 84%
  • Knee 83%
  • Stroke 71%
  • Popliteal Vein 11%
• 2009

  Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial

  Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P. A. G., Reid, J., Murray, G., Venables, G., Rudd, A., Bowler, G. & 14 others, Lewis, S., Rudd, A., Celani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Reid, J., Ting, T., Baigent, C., Bamford, J., Slattery, J., CLOTS Trials Collaboration & Wardlaw, J., Jun 2009, In: The Lancet. 373, 9679, p. 1958-1965 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Compression Stockings 100%
  • Venous Thrombosis 66%
  • Thigh 56%
  • Stroke 47%
  • Randomized Controlled Trials 47%
• 2006

  FOOD: a multicentre randomised trial evaluating feeding policies in patients admitted to hospital with a recent stroke

  FOOD Trial Collaboration, Dennis, M., Lewis, S., Cranswick, G. & Forbes, J., Jan 2006, In: Health Technology Assessment. 10, 2, p. 1+ 109 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • stroke 100%
  • Enteral Nutrition 82%
  • Multicenter Studies 75%
  • Diet 59%
  • Stroke 59%

• Senior physicians' estimates of the likely effects of feeding policies on outcomes prior to the completion of the FOOD trials

  Dennis, M. S., Lewis, S. & Cranswick, G., 18 Jan 2006, In: Age and Ageing. 35, 2, p. 185-7 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Physicians 100%
  • Stroke 54%
  • Randomized Controlled Trials 53%
  • Guidelines 50%
  • Therapeutics 12%
• 2005

  Effect of timing and method of enteral tube feeding for dysphagic stroke patients (FOOD): a multicentre randomised controlled trial

  FOOD Trial Collaboration, Dennis, M. S., Lewis, S. C., Warlow, C. & Cranswick, G., 25 Feb 2005, In: The Lancet. 365, 9461, p. 764-72 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Enteral Nutrition 100%
  • Stroke 63%
  • Randomized Controlled Trials 62%
  • Malnutrition 43%

• Routine oral nutritional supplementation for stroke patients in hospital (FOOD): a multicentre randomised controlled trial

  FOOD Trial Collaboration, Dennis, M. S., Lewis, S. C., Warlow, C. & Cranswick, G., 26 Feb 2005, In: The Lancet. 365, 9461, p. 755-63 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke 100%
  • Randomized Controlled Trials 98%
  • Malnutrition 68%