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Guangzhao Mao

Prof., MS.

Accepting PhD Students

PhD projects

Engineering Nanosensors Using Electrocrystallisation<br/>The overall goal of the project is to create a platform technology for nanosensor scale up by understanding the nanoscale phenomena in electrodeposition. Electroanalytical and nanomaterials characterisation methods will be used to investigate the nucleation and crystal growth mechanisms of charge-transfer complexes on ultramicroelectrodes and nanoelectrode patterns. The knowledge gained will be used to achieve controlled electrodeposition of nanowire sensors on microchips. This project will contribute to UK’s global competitiveness in high-tech areas such as advanced manufacturing of wearable microelectronics and the internet-of-things sensors. <br/><br/>Drug Delivery Nanochemistry<br/>This project involves nanomaterials synthesis, characterisation, and cell assay development for drug delivery targeted to the central nervous system (CNS). In a significant departure from current drug nanocarriers being developed for CNS, this research utilises neural tracing proteins to transport drug molecules within the CNS and bypass the blood-brain barrier.

Personal profile

Biography

Professor Guangzhao Mao

Head of the School of Engineering | Chair Professor of Materials Engineering 

Professor Guangzhao Mao is a leading innovator in nanotechnology and materials engineering, shaping the future of nanomedicine and advanced sensor systems. As Head of the School of Engineering at the University of Edinburgh, she spearheads cutting-edge research that bridges engineering and medicine, unlocking groundbreaking possibilities in drug delivery and nanoscale material applications.

Her pioneering research focuses on two transformative areas:

Electrocrystallization & Nanosensors. Her research unravels the fundamental processes of nucleation and crystal growth in electrodeposition, applying these insights to develop next-generation gas sensors. Her work enhances sensor scalability, with impactful applications in medical diagnostics, environmental monitoring, and industrial automation. Her breakthroughs in integrating nanosensors into larger systems are redefining their real-world potential.

Nanotechnology & Neuroscience. Merging nanotechnology with neuroscience, Mao’s team is developing revolutionary drug delivery systems targeting the central nervous system. Her protein-drug nanoconjugates offer a novel way to bypass the blood-brain barrier (BBB), a long-standing challenge in treating neurological disorders. This innovative approach has already shown promising results in enhancing respiratory function for spinal cord injury, with significant implications for neurodegenerative disease treatments. Her latest advancements include a microfluidic cell-based assay that accelerates drug screening and preclinical evaluations.

Global Recognition & Leadership

Before joining the University of Edinburgh, Professor Mao led as Head of the School of Chemical Engineering at UNSW Sydney, where she continues as an Adjunct Professor. Her global influence is reflected in prestigious accolades, including:✔ Fulbright Senior ScholarshipVisiting Professorship at the Max Planck Institute of Colloids and InterfacesFellow of the American Institute of Chemical Engineers (AIChE)Career Award from the U.S. National Science Foundation

With an impressive track record of driving scientific innovation, Professor Mao continues to push the boundaries of chemical & materials engineering, shaping the next generation of engineering solutions with real-world impact.

Education/Academic qualification

Chemical Engineering, Doctor in Philosophy

Chemistry, Bachelor of Science

Keywords

  • RM Therapeutics. Pharmacology
  • TP Chemical technology

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