Gwo-Tzer Ho

Honorary Consultant Gastroenterologist, FRCP PhD, DR., FRCP PhD, Honorary Consultant Gastroenterologist

Accepting PhD Students

If you made any changes in Pure these will be visible here soon.

Personal profile



My research is focused on 2 main questions:

1. What are the molecular factors that drive and maintain the abnormal mucosal inflammation in Crohn’s disease (CD) and Ulcerative Colitis (UC)?

2. How do we translate this understanding into new and better medical treatments for CD and UC?



My overarching research aim is to translate new knowledge of immune and inflammatory mucosal mechanisms into new therapeutic approaches in IBD. I work very closely with dedicated IBD clinicians, biologists, immunologists and drug development teams with a strong focus on direct studies on human IBD along with in vivo experimental work. Major mechanistic themes are:


1. Gut derived mucosal damage-associated molecular patterns (DAMPs)

2. Mitochondrial dysfunction and ROS-signalling

3. Metabolic programing of the mucosal immune response





Fellow of Royal College of Physicians (Edinburgh)

Medical Research Council (MRC) Clinician Scientist Award

Faculty IBD F1000 section member and Editorial Board IBD Monitor

Doctor of Philosophy (PhD) University of Edinburgh: Clinical and genetic determinants of severe ulcerative colitis

British Society of Gastroenterology CORE Research Prize

European Gastreonterology Rising Star Award

American Gastroenterology Association (3 distinction awards)

European Crohn's and Colitis Organisation Young Investigators Award

Member of Royal College of Physicians Edinburgh

MBChB University of Glasgow



  • R Medicine (General)
  • QH301 Biology


Dive into the research topics where Gwo-Tzer Ho is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or