Gwo-Tzer Ho

Search results

• Active

  Fibrosis Associated Protein Inhibitor (FAPI) radiotracer-based imaging to identify fibrotic intestinal Crohn's Disease (FATE-CD)

  Kalla, R. (Principal Investigator), Ho, G.-T. (Co-investigator) & Newby, D. (Co-investigator)

  Medical Research Council

  1/12/23 → 30/11/26

  Project: Research

• Non-invasive technologies for diagnosis and monitoring of inflammatory bowel diseases

  Vendrell Escobar, M. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  UKRI (formerly RCUK)

  1/09/23 → 31/08/26

  Project: Research

• Translating a novel blood multi-protein biomarker using PEA-technology for prospective mucosal healing in UC

  Kalla, R. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  Crohn's and Colitis UK

  3/04/23 → 6/07/26

  Project: Research

• Investigating the role of Microfold (M) Cells in the gut mucosal immune response in the early stages of Crohn’s disease

  Ho, G.-T. (Principal Investigator) & Cavanagh, A. (Co-investigator)

  Pathological Society

  1/08/22 → 31/07/25

  Project: Research

• Mitochondrial Anti-oxidant therapy to Resolve Inflammation in Ulcerative Colitis (MARVEL): A randomised placebo-controlled trial on oral MitoQ in moderate to severe active UC

  Ho, G.-T. (Principal Investigator) & Norrie, J. (Co-investigator)

  Jon Moulton Foundation Trust

  1/08/19 → 28/02/26

  Project: Research

• Mitochondrial DAMPs As Mechanistic Biomarkers Of Mucosal Inflammation In Crohn's Disease (MUSIC)

  Ho, G.-T. (Principal Investigator), Norrie, J. (Co-investigator), Rossi, A. (Co-investigator) & Wilson, D. (Co-investigator)

  The Leona M. And Harry B. Helmsley

  1/03/19 → 28/02/26

  Project: Research

• Finished

  Combination therapy with BIOlogics and Partial enteral nutrition In adults with active ileocolonic Crohn’s disease. The BIOPIC Study

  Ho, G.-T. (Principal Investigator)

  University of Glasgow

  1/09/22 → 31/03/25

  Project: Research

• Characterising the role of M-cells in the ageing human gut and in inflammatory bowel disease

  Ho, G.-T. (Principal Investigator)

  Pathological Society

  1/09/21 → 31/07/22

  Project: Research

• Characterising the role of M-cells in the ageing human gut and in inflammatory bowel disease

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  1/09/21 → 31/07/22

  Project: Research

• Investigating mitochondrial dysfunction in determining the innate colonic epithelial phenotype in Ulcerative Colitis (UC): Developing a cell-based gut repair approach using human organoid technology

  Ho, G.-T. (Principal Investigator), Henderson, N. (Co-investigator) & Jones, G. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  4/08/21 → 3/08/24

  Project: Research

• Investigating mitochondrial dysfunction in determining the innate colonic epithelial phenotype in Ulcerative Colitis (UC): Developing a cell-based gut repair approach using human organoid technology

  Ho, G.-T. (Principal Investigator), Henderson, N. (Co-investigator) & Jones, G. (Co-investigator)

  Scottish Executive

  4/08/21 → 3/08/24

  Project: Research

• Decoding macrophage functional heterogeneity in the pathogenesis of Crohn's disease

  Jones, G. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  Wellcome Trust (Rcl)

  1/04/21 → 31/03/25

  Project: Research

• Decoding macrophage functional heterogeneity in the pathogenesis of Crohn's disease

  Jones, G. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  UK-based charities

  1/10/20 → 30/09/24

  Project: Research

  • Tissue Repair 100%
  • Macrophage 81%
  • Salivary Gland 73%
  • Alveolar Macrophage 73%
  • Transcription Factors 73%

• Mini-MARVEL (Mitochondrial Antioxidant therapy to Resolve Inflammation in Ulcerative Colitis): A phase 2b randomised placebo-controlled trial of oral MitoQ in mild-to-moderately active paediatric UC

  Norrie, J. (Principal Investigator), Ho, G.-T. (Co-investigator) & Wilson, D. (Co-investigator)

  Jon Moulton Foundation Trust

  1/09/20 → 31/10/24

  Project: Research

• Mini-MARVEL (Mitochondrial Antioxidant therapy to Resolve Inflammation in Ulcerative Colitis): A phase 2b randomised placebo-controlled trial of oral MitoQ in mild-to-moderately active paediatric UC

  Wilson, D. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  UK-based charities

  1/06/20 → 31/10/24

  Project: Research

• Host danger signals in determining the severity of Covid19: Blocking damage associated molecular patterns (DAMPs) as new stratified treatment approach in STOPCOVID

  Ho, G.-T. (Principal Investigator), Dorward, D. (Co-investigator), Gray, R. (Co-investigator) & Rossi, A. (Co-investigator)

  UK-based charities

  1/05/20 → 31/05/21

  Project: Research

• Investigating cathelicidin blockade as a novel therapeutic for inflamnmatory bowel diseases

  Gwyer Findlay, E. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  1/10/19 → 31/12/20

  Project: Research

• Mitochondrial Anti-oxidant therapy to Resolve Inflammation in Ulcerative Colitis (MARVEL): A randomised placebo-controlled trial on oral MitoQ in moderate to severe active UC

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  1/07/19 → 31/12/24

  Project: Research

• In vitro analysis of whole blood immune responses to different strains of Plasmodium parasite

  Williams, A. (Principal Investigator), Becker, C. (Co-investigator), Davies, J. (Co-investigator), Ho, G.-T. (Co-investigator), Kind, P. (Co-investigator) & Spence, P. (Co-investigator)

  UK-based charities

  3/06/19 → 15/07/19

  Project: Research

• Mitochondrial DAMPs As Mechanistic Biomarkers Of Mucosal Inflammation In Crohn's Disease (MUSIC)

  Rossi, A. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  Non-EU-based charities

  1/03/19 → 28/02/23

  Project: Research

• Blocking Gut Danger Signals as treatment for Inflammatory Bowel Disease

  Ho, G.-T. (Principal Investigator), Dransfield, I. (Co-investigator) & Gwyer Findlay, E. (Co-investigator)

  UK-based charities

  1/02/19 → 1/09/22

  Project: Research

• Resolving inflammation in IBD: Developing a new therapeutic approach by targeting pro-inflammatory mitochondrial formylated peptides on neutrophil FPR1-pathway

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  1/02/19 → 31/05/22

  Project: Research

• To investigate the role of gut mucosal damage-associated molecular patterns (DAMPs) in the pathogenesis of IBD

  Ho, G.-T. (Principal Investigator)

  Genentech Inc

  1/01/19 → 19/12/23

  Project: Research

• Investigating the Molecular Heterogeniety of Intestinal Macrophages in Drug Naive, Newly Diagnosed Crohn's Disease Patients

  Ho, G.-T. (Principal Investigator), Bain, C. (Co-investigator) & Jones, G. (Co-investigator)

  UK-based charities

  1/01/19 → 31/12/19

  Project: Research

• To investigate the role of gut mucosal damage-associated molecular patterns (DAMPs) in the pathogenesis of IBD

  Ho, G.-T. (Principal Investigator)

  Non-EU industry, commerce and public corporations

  1/01/19 → 19/12/23

  Project: Research

• Prognostic markers for Inflammatory bowel disease (IBD): Using DNA methylation to predict disease outcomes

  Nimmo, E. (Principal Investigator) & Ho, G.-T. (Co-investigator)

  UK-based charities

  1/09/17 → 31/08/18

  Project: Research

• Investigating the role of mitophagy in inflammatory bowel diseases.

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  27/06/16 → 7/08/16

  Project: Research

• Investigating the role of mitochondrial damage associated molecular patterns (mDAMPs) in the pathogenesis of IBD

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  1/06/16 → 31/05/17

  Project: Research

• Characterisation of mitochondrial respiratory function in primary gut tissue in mouse models of colitis and human IBD.

  Ho, G.-T. (Principal Investigator)

  UK-based charities

  23/05/16 → 17/07/16

  Project: Research

  • Enteritis 100%
  • Multidrug Resistance 100%
  • Homeostasis 100%
  • Colitis 50%
  • Inflammatory Bowel Disease 50%

• Characterisation of autophagic clearance of mitochondrial damage associated molecular patterns in inflammatory bowel disease

  Ho, G.-T. (Principal Investigator)

  4/01/16 → 31/07/16

  Project: MVM - (non-funded) undergraduate research project

  • Inflammatory Bowel Disease 100%
  • Mitochondrion 60%
  • Autophagy 40%
  • Ulcerative Colitis 40%
  • Crohn's Disease 40%

• Mitochondria damage associated molecular patterns in IBD

  Ho, G.-T. (Principal Investigator)

  1/12/14 → 1/06/16

  Project: University Awarded Project Funding

  • Inflammatory Bowel Disease 100%
  • Gut 100%
  • Ulcerative Colitis 25%
  • Biological Marker 25%
  • Crohn's Disease 25%

• Modulation of a P-glycoptotien 170 function as a therapeutic target in the ulcerative cells.

  Ho, G.-T. (Principal Investigator)

  MRC

  1/12/08 → 30/11/13

  Project: Research

  • Inflammatory Bowel Disease 100%
  • Gut 100%
  • Ulcerative Colitis 25%
  • Biological Marker 25%
  • Crohn's Disease 25%