Personal profile
Biography
My main area of research is linking neuroimaging techniques with underlying biology in a bottom-up approach in order to better understand debilitating neuropsychiatric disorders. My research focuses on how causal risk factors, such as genetic or environmental, contribute to disease in terms of impact on brain structure and function and on developmental trajectory.
External positions
Forum Chair PR UK
30 Sept 2001 → …
Chief Scientist Generation Scotland
31 Jan 2001 → …
Research Themes and Networks
- Edinburgh Mental Health Network
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
A genetic study of immunity in depression and interactions with childhood maltreatment
Herrera-Rivero, M., McCartney, D. L., Whalley, H. C., Berger, K., McIntosh, A. M. & Baune, B. T., 19 Mar 2026, (E-pub ahead of print) In: Translational Psychiatry. 16, 1Research output: Contribution to journal › Article › peer-review
Open AccessFile -
GS-BrainText: A multi-site brain imaging report dataset from Generation Scotland for clinical natural language processing development and validation
Alex, B., Grover, C., Casey, A., Tobin, R., Whalley, H. & Whiteley, W. N., 19 Mar 2026, (Accepted/In press) GS-BrainText: A Multi-Site Brain Imaging Report Dataset from Generation Scotland for Clinical Natural Language Processing Development and Validation. ACL AnthologyResearch output: Chapter in Book/Report/Conference proceeding › Conference contribution
-
Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 367 988 people using natural language processing
Iveson, M. H., Mukherjee, M., Davidson, E. M., Zhang, H., Sherlock, L., Ball, E. L., Mair, G., Hosking, A., Whalley, H., Poon, M. T. C., Wardlaw, J. M., Kent, D., Tobin, R., Grover, C., Alex, B. & Whiteley, W., 13 Mar 2026, In: Journal of Neurology, Neurosurgery & Psychiatry. p. jnnp-2025-337689Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Childhood Maltreatment and Deviations from Normative Brain Structure: A Mega-Analysis of 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD Working Groups
Wang, H. R., Liu, Z.-Q., Pozzi, E., Hussain, A., Sigar, P., Abdallah, C., Alexander, N., Baker, J., Bauer, J., Blackford, J. U., Cisler, J., Connolly, C. G., Cotton, A., Daniels, J., Dannlowski, U., Densmore, M., deRoon-Cassini, T., Dima, D., Du Plessis, S. & Etkin, A. & 89 others, , 4 Mar 2026, (E-pub ahead of print) In: Biological Psychiatry.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
dGAMLSS: An exact, distributed algorithm to fit Generalized Additive Models for Location, Scale, and Shape for privacy-preserving population reference charts
Hu, F., Tong, J., Gardner, M., Lifespan Brain Chart Consortium, Chen, A. A., Bethlehem, R. A. I., Seidlitz, J., Li, H., Alexander-Bloch, A., Chen, Y. & Shinohara, R. T., 14 Jan 2026, In: Bioinformatics. 42, 1, btaf625.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
-
Keynote talk
Whalley, H. (Assessor)
4 Dec 2025Activity: Academic talk or presentation types › Oral presentation
-
Plenary talk @ Scotlands Health Research and Innovation Conference
Whalley, H. (Assessor)
31 Oct 2023Activity: Academic talk or presentation types › Oral presentation
-
Annual Distinguished Christmas Lecture
Whalley, H. (Assessor)
8 Dec 2022Activity: Academic talk or presentation types › Invited talk
-
Beautiful Brains Public Lecture
Whalley, H. (Advisor)
24 Nov 2022Activity: Participating in or organising an event types › Public Engagement – Public lecture/debate/seminar
-
Depression Detectives
Beange, I. (Organiser), McIntosh, A. (Speaker), Whalley, H. (Speaker), Chan, S. (Speaker), MacSweeney, N. (Speaker), Barbu, M. C. (Speaker), Romaniuk, L. (Speaker), Ecks, S. (Speaker), Adams, M. (Speaker), Huggins, C. (Speaker), Kwong, A. (Speaker), Smith, D. (Speaker), Goodall, K. (Speaker), Happer, R. (Speaker) & Iveson, M. (Speaker)
2021 → …Activity: Participating in or organising an event types › Public Engagement – Public lecture/debate/seminar
Prizes
-
-
CMVM College team award (to Generation Scotland)
Whalley, H. (Recipient), 4 Apr 2025
Prize: Prize (including medals and awards)
-
Good Research Practice Award
Beange, I. (Recipient), McIntosh, A. (Recipient), Adams, M. (Recipient), Whalley, H. (Recipient), Kirkham, E. (Recipient), Iveson, M. (Recipient), Kwong, A. (Recipient), Lewins, M. (Recipient), Chan, S. (Recipient), MacSweeney, N. (Recipient), Barbu, M. (Recipient), Romaniuk, L. (Recipient), Ecks, S. (Recipient), Higgins, C. (Recipient), Smith, D. (Recipient), Campbell, M. A. (Recipient), Goodall, K. (Recipient), Christie, H. (Recipient), Happer, R. (Recipient) & Boynton, P. M. (Recipient), Dec 2022
Prize: Prize (including medals and awards)
-
Medical Research Council Data Pathfinder (Co-I)
Sibley, H. (Recipient), 1 Apr 2018
Prize: Other distinctions
-
Medical Research Scotland 4 year funded PhD Studentship (Co-I)
Sibley, H. (Recipient), 1 Apr 2018
Prize: Other distinctions
-
A phase II RCT of Oral Cannabinoid versus placebo in the treatment of chemotherapy induced peripheral neuropathic pain (ACTION)
Whalley, H. (Principal Investigator), Fallon, M. (Co-investigator), Hall, P. (Co-investigator) & Weir, C. (Co-investigator)
National Institute for Health Research
1/10/24 → 31/03/27
Project: Research
-
Hub For Metabolic Psychiatry
Smith, D. (Principal Investigator), McIntosh, A. (Co-investigator), Whalley, H. (Co-investigator), Lawrie, S. (Co-investigator) & Campbell, I. (Principal Investigator)
1/04/24 → 31/03/29
Project: Research
-
Understanding The Causal Mechanisms Of Antidepressant Exposure And Response
Lewis, C. M. (Principal Investigator), Whalley, H. (Co-investigator), McIntosh, A. (Co-investigator), Iveson, M. (Researcher), Beange, I. (Researcher), Somerville, M. (Researcher), Falis, M. (Researcher), Douglas, C. (Researcher), Calnan, M. (Researcher), Edmondson-Stait, A. (Researcher) & Smith, H. (Researcher)
1/08/23 → 31/07/28
Project: Research
-
Preterm birth, Neurodevelopment and Cognition in Children: Causal Evidence and Mechanisms
Boardman, J. (Principal Investigator), Cox, S. (Co-investigator), Marioni, R. (Co-investigator), Reynolds, R. (Co-investigator), Richardson, H. (Co-investigator), Tsanas, T. (Co-investigator) & Whalley, H. (Co-investigator)
1/11/22 → 31/10/27
Project: Research
-
Integrated gene and brain mapping of language and reading abilities
Luciano, M. (Principal Investigator), Marioni, R. (Co-investigator) & Whalley, H. (Co-investigator)
Biotechnology and Biological Sciences Research Council
1/02/20 → 27/01/27
Project: Research
Datasets
-
STratifying Resilience and Depression Longitudinally (STRADL): A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments
Adams, M. (Creator), McIntosh, A. (Owner), Hawkins, E. (Data Manager), Habota, T. (Creator), Steele, J. D. (Creator), Whalley, H. (Creator), Porteous, D. (Project Leader), Deary, I. (Project Leader), Murray, A. (Creator) & Campbell, A. (Data Manager), Edinburgh DataVault, 2019
DOI: 10.7488/8f68f1ae-0329-4b73-b189-c7288ea844d7
Dataset
-
ENIGMA HALFpipe task-based functional MRI STRADL Project
Whalley, H. (Owner) & Tatham, R. (Creator), Edinburgh DataVault, 21 May 2025
DOI: 10.7488/4fb44cb6-68ef-4ee2-b6ec-45320d390548
Dataset
-
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Howard, D. (Creator), Adams, M. (Creator), Clarke, T.-K. (Creator), Hafferty, J. (Creator), Gibson, J. (Creator), Shirali, M. (Creator), Coleman, J. (Creator), Ward, J. (Creator), Wigmore, E. (Creator), Alloza, C. (Creator), Barbu, M. (Creator), Xu, E. (Creator), Sibley, H. (Creator), Marioni, R. (Creator), Porteous, D. (Creator), Davies, G. (Creator), Deary, I. (Creator), Hemani, G. (Creator), Tian, C. (Creator), Hinds, D. (Creator), Team, 2. R. (Creator), Consortium, M. D. D. W. G. O. T. P. G. (Creator), Trzaskowshi, M. (Creator), Byrne, E. (Creator), Ripke, S. (Creator), Smith, D. (Creator), Sullivan, P. (Creator), Wray, N. (Creator), Breen, G. (Creator), Shen, X. (Creator), Lewis, C. (Creator) & McIntosh, A. (Creator), Edinburgh DataShare, 30 Jan 2019
DOI: 10.7488/ds/2458
Dataset
-
Scottish Family Mental Health (SFMH) Study Dataset
Cooper, A. (Creator), Blackwood, D. (Creator), Lawrie, S. (Creator), McIntosh, A. (Creator), Romaniuk, L. (Creator), Semple, S. (Creator), Duff, B. (Creator) & Whalley, H. (Creator), Edinburgh DataVault, 10 Oct 2023
DOI: 10.7488/7f08e5f1-b300-4a32-bd18-ef511f82c390
Dataset
-
Generation Scotland Age x Sex Epigenome Wide Association Study Summary Statistics
Boutin, T. (Creator), Morris, S. (Creator), Campbell, A. (Creator), Murray, A. (Creator), Whalley, H. (Creator), Hayward, C. (Creator), Evans, K. (Creator), Chandra, T. (Creator), Deary, I. (Creator), McIntosh, A. (Creator), Yang, J. (Creator), Visscher, P. (Creator), McRae, A. (Creator), Marioni, R. (Creator), Porteous, D. (Creator), McCartney, D. (Creator), Zhang, F. (Creator), Hillary, R. (Creator), Zhang, Q. (Creator), Stevenson, A. (Creator), Walker, R. (Creator) & Bermingham, M. (Creator), Edinburgh DataShare, 31 Jan 2020
DOI: 10.7488/ds/2709
Dataset
Press/Media
-
-
-
Med Res Scot Academy live lesson 2024
15/03/24
1 Media contribution
Press/Media: Public Engagement Activities
-
Annual Distinguished Christmas Lecture
8/12/22
1 Media contribution
Press/Media: Public Engagement Activities
-
Research indicates the brain does not fully mature until you are at least 25
28/02/20
1 Media contribution
Press/Media: Press Release