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Dive into the research topics where Iain McNae is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces
Li, C., Urem, M., Kotsogianni, I., Lau, J., Du, C., Elsayed, S. S., Martin, N. I., McNae, I. W., Voskamp, P., Mayer, C., Rigali, S., Pannu, N., Abrahams, J. P., von Borzyskowski, L. S. & van Wezel, G. P., 25 Nov 2025, In: PLoS Biology. 23, 11, 27 p., e3003514.Research output: Contribution to journal › Article › peer-review
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pyRBDome: a comprehensive computational platform for enhancing RNA-binding proteome data
Chu, L.-C., Christopoulou, N., McCaughan, H., Winterbourne, S., Cazzola, D., Wang, S., Litvin, U., Brunon, S., Harker, P. J., McNae, I. & Granneman, S., Oct 2024, In: Life Science Alliance. 7, 10, 22 p., e202402787.Research output: Contribution to journal › Article › peer-review
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Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice
McNae, I. W., Kinkead, J., Malik, D., Yen, L.-H., Walker, M. K., Swain, C., Webster, S. P., Gray, N., Fernandes, P. M., Myburgh, E., Blackburn, E. A., Ritchie, R., Austin, C., Wear, M. A., Highton, A. J., Keats, A. J., Vong, A., Dornan, J., Mottram, J. C. & Michels, P. A. M. & 2 others, , 16 Feb 2021, In: Nature Communications. 12, 1, 10 p., 1052.Research output: Contribution to journal › Article › peer-review
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Biochemical and transcript level differences between the three human phosphofructokinases show 3 optimisation of each isoform for specific metabolic niches
Fernandes, P., Kinkead, J., McNae, I., Michels, P. & Walkinshaw, M. D., 27 Nov 2020, In: Biochemical Journal. 47, 22, p. 4425–4441 17 p.Research output: Contribution to journal › Article › peer-review
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Kinetic and structural studies of Trypanosoma and Leishmania phosphofructokinases show evolutionary divergence and identify AMP as a switch regulating glycolysis versus gluconeogenesis
Fernandes, P., Kinkead, J., McNae, I., Vásquez-Valdivieso, M. G., Wear, M., Michels, P. & Walkinshaw, M., 15 Dec 2019, (E-pub ahead of print) In: The FEBS Journal.Research output: Contribution to journal › Article › peer-review
Open AccessFile