Personal profile
Research Interests
Mammalian gene regulation and disease genetics.
Biography
James completed his PhD in bioinformatics and statistical genetics in 2007 from the University of Edinburgh, and following positions at the European Bioinformatics Institute and University College Dublin returned to Edinburgh to work first at the MRC Human genetics unit before joining the Roslin in 2013. James’s group is focused on understanding mammalian gene regulation, genome evolution and human and animal disease genetics.
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Widespread signatures of recent selection linked to nucleosome positioning in the human lineage
Prendergast, J. G. D. & Semple, C. A. M., 2011, In: Genome Research. 21, 11, p. 1777-87 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
Tenesa, A., Farrington, S. M., Prendergast, J., Porteous, M. E., Walker, M., Haq, N., Barnetson, R., Theodoratou, E., Cetnarskyj, R., Cartwright, N., Semple, C., Clark, A. J., Reid, F., Smith, L., Kavoussanakis, K., Koessler, T., Pharoah, P. D., Buch, S., Schafmayer, C. & Tepel, J. & 37 others, , May 2008, In: Nature Genetics. 40, 5, p. 631-7 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
The Colorectal Tumour Gene Identification (CORGI) Consortium, The Swedish Low-Risk Colorectal Cancer Study Group, The COIN Collaborative Group & Tomlinson, I., Jul 2012, In: Nature Genetics. 44, 7, p. 770-776 7 p.Research output: Contribution to journal › Article › peer-review
-
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
CORGI Consortium, Tomlinson, I. P. M., Webb, E., Carvajal-Carmona, L., Broderick, P., Howarth, K., Pittman, A. M., Spain, S., Lubbe, S., Walther, A., Sullivan, K., Jaeger, E., Fielding, S., Rowan, A., Vijayakrishnan, J., Domingo, E., Chandler, I., Kemp, Z., Qureshi, M. & Farrington, S. M. & 31 others, , May 2008, In: Nature Genetics. 40, 5, p. 623-630 8 p.Research output: Contribution to journal › Article › peer-review
-
Sequencing and analysis of an Irish human genome
Tong, P., Prendergast, J., Lohan, A. J., Farrington, S. M., Cronin, S., Friel, N., Bradley, D. G., Hardiman, O., Evans, A., Wilson, J. F. & Loftus, B., 2010, In: Genome Biology. 11, 9, p. - 14 p., R91.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 1 Participation in workshop, seminar, course
-
Genus: Bos! Short-talks on Roslin & SRUC
Whitelaw, B. (Speaker), Coffey, M. (Speaker), Mwacharo, J. (Speaker), Gorjanc, G. (Speaker), Roehe, R. (Speaker), Watson, M. (Speaker), Warr, A. (Speaker), Prendergast, J. (Speaker), Clark, E. (Speaker), Wilson, A. (Speaker), Pocrnic, I. (Chair) & Janes, M. (Contributor)
16 Mar 2022Activity: Participating in or organising an event types › Participation in workshop, seminar, course
-
Understanding the molecular basis for comparable Theileria annulata and Theileria parva pathogenesis
Hassan, M. (Principal Investigator), Connelley, T. (Co-investigator), Morrison, L. (Co-investigator) & Prendergast, J. (Co-investigator)
Biotechnology and Biological Sciences Research Council
1/03/26 → 28/02/29
Project: Research
-
AI-Guided Genome Editing: Developing tissue-specific regulatory elements for livestock trait improvement
Prendergast, J. (Principal Investigator) & Hassan, M. (Co-investigator)
1/09/25 → 31/08/27
Project: Research
-
Generating livestock cell lines with landing pads for efficient transgene expression
Grey, F. (Principal Investigator), Bean, T. (Co-investigator), Burdon, T. (Co-investigator), Lillico, S. (Co-investigator), McGrew, M. (Co-investigator), Prendergast, J. (Co-investigator), Rainger, J. (Co-investigator) & Tait-Burkard, C. (Co-investigator)
Biotechnology and Biological Sciences Research Council
1/09/25 → 31/08/27
Project: Research
-
Engineering biology for healthier pork
Donadeu, X. (Principal Investigator) & Prendergast, J. (Co-investigator)
1/09/25 → 31/12/26
Project: Research
-
IDG2023/28 - PP2025 - Exploring biological limits of inbreeding: the case of Chillingham wild cattle
Pocrnic, I. (Principal Investigator), Prendergast, J. (Co-investigator) & Rochus, C. (Co-investigator)
Biotechnology and Biological Sciences Research Council
1/06/25 → 31/03/26
Project: Research
Datasets
-
Profiling the Immune Epigenome across Global Cattle Breeds
Powell, J. (Creator), Morrison, L. (Supervisor), Prendergast, J. (Supervisor), Simpson, C. (Data Manager) & Connelley, T. (Supervisor), Edinburgh DataVault, 2021
DOI: 10.7488/36997bd6-42cc-4e03-881b-17f56d36d129
Dataset
-
PacBio HiFi raw data of a Boran bull
Wragg, D. (Creator) & Prendergast, J. (Creator), Edinburgh DataVault, 2021
DOI: 10.7488/502653f6-122e-400d-b4b5-c8594a70f1df
Dataset
-
-
Whole genome sequencing data for worldwide cattle and Bos species
Talenti, A. (Creator) & Prendergast, J. (Creator), Edinburgh DataVault, 10 Jul 2020
Dataset
-
Boran BovineHD SNP data
Prendergast, J. (Creator), Edinburgh DataShare, 28 Jan 2022
DOI: 10.7488/ds/2985
Dataset