Personal profile
Research Interests
Brain connectivity
Network theory
Matrix and tensor decomposition
Nonlinear analysis
Machine learning for physiological data
Alzheimer's disease and dementia
Epilepsy
Intensive care unit data
My research in a nutshell
My research group creates and applies data science techniques to extract information from biomedical signals and clinical time series.
Our main aim is to reveal the subtle changes that major diseases (e.g., Alzheimer's and epilepsy) cause in the brain activity.
In collaboration with researchers at Edinburgh, across the UK and overseas, we are currently working in the processing and analysis of biomedical signals, particularly human brain activity. By developing and applying signal processing methods, we aim at increasing our understanding of how several brain conditions progress. Of particular interest is the evaluation of brain functional connectivity in both neurodevelopmental and neurodegenerative diseases to understand how they affect the way in which different brain regions interact with each other. We are also interested in the interplay between structure and function in the brain and in the application of pattern recognition techniques to highly-dimensional clinical datasets to support decision making.
If you want to know more, check out my "Research in a nutshell" video: Biosignal processing
Current Research Interests
Brain connectivity
Network theory
Matrix and tensor decomposition
Nonlinear analysis
Machine learning for physiological data
Alzheimer's disease and dementia
Epilepsy
Intensive care unit data
Websites
Education/Academic qualification
Doctor of Philosophy (PhD), Applications of Blind Source Separation to the Magnetoencephalogram Background Activity in Alzheimer's Disease, University of Valladolid
Award Date: 1 Jan 2010
Master of Engineering, University of Valladolid
Award Date: 1 Jan 2005
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Collaborations and top research areas from the last five years
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Graph-Based Multivariate Multiscale Dispersion Entropy: Efficient Implementation and Applications to Real-World Network Data
Fabila-Carrasco, J. S., Lei, M.-S. M., Tan, C. & Escudero, J., 28 Apr 2026, (E-pub ahead of print) In: IEEE Transactions on Signal and Information Processing Over Networks. 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The exposome of brain aging across 34 countries
Legaz, A., Moguilner, S., Barttfeld, P., Cuadros Castro, J., Galván Rial, D. S., Migeot, J., Farina, F. R., Gonzalez-Gomez, R., Salazar-Londoño, S., de Souza Azzi, T., Alcauter, S., Amoruso, L., Anghinah, R., Bakr, M., Behrens, M. I., Bruno, M. A., Cardona, J. F., Chen, C., Colliot, O. & Custodio, N. & 123 others, , 3 Apr 2026, (E-pub ahead of print) In: Nature Medicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Absence seizures and sleep-wake abnormalities in a rat model of GRIN2B neurodevelopmental disorder
Hristova, K., Fasol, M., McLaughlin, N., Nawaz, M. S., Taskiran, M., Buller-Peralta, I., Harris, A., Sutherland, A., Bassi, A., Ocampo-Garces, A., Escudero, J., Kind, P. C. & Gonzalez-Sulser, A., 1 Dec 2025, In: Epilepsia. 66, 12, p. 4996-5013Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Creative experiences and brain clocks
Coronel-Oliveros, C., Migeot, J., Lehue, F., Amoruso, L., Kowalczyk-Grębska, N., Jakubowska, N., Mandke, K. N., Seabra, J. P., Orio, P., Campbell, D., Gonzalez-Gomez, R., Prado, P., Cuadros, J., Tagliazucchi, E., Cruzat, J., Legaz, A., Medel, V., Hernandez, H., Fittipaldi, S. & Altschuler, F. & 30 others, , Dec 2025, In: Nature Communications. 16, 1, p. 8336 8336.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
CLaI: Collaborative Learning and Inference for low-resolution physiological signals – Validation in clinical event detection and prediction
Haule, H., Piper, I., Jones, P., Lo, T.-Y. M. & Escudero, J., Nov 2025, In: IEEE Transactions on Biomedical Engineering. 72, 11, p. 3186-3195 10 p., 10974669.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
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Permutation Entropy for Graph Signals: Theoretical Framework and Application to Neuroimaging Data
Escudero, J. (Invited speaker)
16 Jul 2025Activity: Academic talk or presentation types › Invited talk
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47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Escudero, J. (Organiser), Shetty, J. (Organiser) & Chybowski, B. (Invited speaker)
16 Jul 2025Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Epilepsy Research Institute UK Conference
Escudero, J. (Invited speaker)
21 May 2025Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Una Europa Epilepsy Data Challenge
Escudero Rodriguez, J. (Invited speaker)
24 Apr 2025Activity: Academic talk or presentation types › Invited talk
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IEEE Transactions on Biomedical Engineering (Journal)
Escudero, J. (Associate editor)
Feb 2025 → …Activity: Publication peer-review and editorial work types › Editorial activity
Prizes
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3rd place Award in the EMBC17 international student paper competition
Kinney-lang, E. (Recipient), Spyrou, L. (Recipient), Ebied, A. (Recipient), Chin, R. (Recipient) & Escudero, J. (Recipient), Jul 2017
Prize: Prize (including medals and awards)
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Elevation to Senior Member of the IEEE
Escudero Rodriguez, J. (Recipient), Oct 2019
Prize: Election to learned society
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Member of the Young Academy of Scotland
Escudero Rodriguez, J. (Recipient), Aug 2016
Prize: Election to learned society
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Nightingale Award 2018
Azami, H. (Recipient), Fernandez, A. (Recipient) & Escudero, J. (Recipient), Jun 2018
Prize: Prize (including medals and awards)
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Top paper published in 2018 by the journal BJGP Open
Escudero Rodriguez, J. (Recipient), 25 Jan 2019
Prize: Other distinctions
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An Artificial Intelligence EEG Biomarker for SYNGAP1 - SYNGAP Research Fund
Gonzalez Sulser, A. (Principal Investigator) & Escudero Rodriguez, J. (Co-investigator)
1/04/26 → 29/02/28
Project: Research
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Enabling the early and equitable diagnosis of epilepsy in infants in the community (EPIC)
Escudero Rodriguez, J. (Principal Investigator), Gonzalez Sulser, A. (Co-investigator), Lo, M. (Co-investigator), Shetty, J. (Co-investigator), Smith, L. (Co-investigator), Stanfield, A. (Co-investigator) & Tsaftaris, S. (Co-investigator)
Engineering and Physical Sciences Research Council
1/01/26 → 31/12/28
Project: Research
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CHAI - EPSRC AI Hub for Causality in Healthcare AI with Real Data
Tsaftaris, S. (Principal Investigator), Baillie, K. (Co-investigator), Beentjes, S. (Co-investigator), Crowley, E. (Co-investigator), Escudero Rodriguez, J. (Co-investigator), Gouk, H. (Co-investigator), Guthrie, B. (Co-investigator), Harrison, E. (Co-investigator), Khamseh, A. (Co-investigator), King, R. (Co-investigator), Nazarpour, K. (Co-investigator), Parsons, M. (Co-investigator), Ramamoorthy, R. (Co-investigator), Seth, S. (Co-investigator), Simpson, I. (Co-investigator) & Whiteley, W. (Co-investigator)
Engineering and Physical Sciences Research Council
1/02/24 → 31/01/29
Project: Research
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A Window in the Brain: Novel seizure detection tool development in paediatric critical care
Abdullateef, S. (Researcher), Escudero Rodriguez, J. (Co-investigator), Nenadovic, V. (Co-Investigator (External)), McLellan, A. (Collaborator) & Lo, T.-Y. M. (Principal Investigator)
1/12/20 → …
Project: Research
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Collaborative Learning and Inference for Brain Data
Escudero Rodriguez, J. (Principal Investigator)
Engineering and Physical Sciences Research Council
1/11/25 → 31/03/26
Project: Research
Datasets
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Matlab codes related to "Weighted network estimation by the use of topological graph metrics"
Escudero Rodriguez, J. (Creator) & Spyrou, L. (Creator), Edinburgh DataShare, 29 Jun 2018
DOI: 10.7488/ds/2369, https://datashare.is.ed.ac.uk/handle/10283/3110
Dataset
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Matlab codes for "Refined Composite Multivariate Generalized Multiscale Fuzzy Entropy: A Tool for Complexity Analysis of Multichannel Signals"
Azami, H. (Creator) & Escudero Rodriguez, J. (Creator), Edinburgh DataShare, 20 Jul 2016
DOI: 10.7488/ds/1432
Dataset
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Matlab codes for "Improved Multiscale Permutation Entropy for Biomedical Signal Analysis: Interpretation and Application to Electroencephalogram Recordings"
Azami, H. (Creator) & Escudero Rodriguez, J. (Creator), Edinburgh DataShare, 26 Jul 2015
DOI: 10.7488/ds/273
Dataset
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Matlab codes for "The Complex Hierarchical Topology of EEG Functional Connectivity"
Smith, K. (Creator) & Escudero Rodriguez, J. (Creator), Edinburgh DataShare, 7 Nov 2016
DOI: 10.7488/ds/1520
Dataset
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Matlab codes for "Refined Composite Multiscale Dispersion Entropy and its Application to Biomedical Signals"
Azami, H. (Creator) & Escudero Rodriguez, J. (Creator), Edinburgh DataShare, 4 Mar 2017
DOI: 10.7488/ds/1982, http://datashare.is.ed.ac.uk/handle/10283/2637
Dataset
Press/Media
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EEG Biomarkers: The Future of Monitoring Neurological Health?
17/07/25
1 Media contribution
Press/Media: Expert Comment
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Computational brain models map diversity embedded in aging and dementia
Ibanez, A., Baez, S. & Escudero Rodriguez, J.
10/10/24
1 Media contribution
Press/Media: Expert Comment
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What accelerates brain ageing? This AI ‘brain clock’ points to answers
27/08/24
1 Media contribution
Press/Media: Research
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Research reveals environmental and disease factors can speed up the brain's biological age
26/08/24
1 item of Media coverage
Press/Media: Research
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Danger to science of no-deal Brexit
Pinto da Costa, M., Allegra, A., Escudero Rodriguez, J. & Makowska, K.
13/08/19
1 Media contribution
Press/Media: Other