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  • 2010

    New loci associated with kidney function and chronic kidney disease

    Köttgen, A., Pattaro, C., Böger, C. A., Fuchsberger, C., Olden, M., Glazer, N. L., Parsa, A., Gao, X., Yang, Q., Smith, A. V., O'Connell, J. R., Li, M., Schmidt, H., Tanaka, T., Isaacs, A., Ketkar, S., Hwang, S-J., Johnson, A. D., Dehghan, A., Teumer, A. & 112 others, Paré, G., Atkinson, E. J., Zeller, T., Lohman, K., Cornelis, M. C., Probst-Hensch, N. M., Kronenberg, F., Tönjes, A., Hayward, C., Aspelund, T., Eiriksdottir, G., Launer, L. J., Harris, T. B., Rampersaud, E., Mitchell, B. D., Arking, D. E., Boerwinkle, E., Struchalin, M., Cavalieri, M., Singleton, A., Giallauria, F., Metter, J., de Boer, I. H., Haritunians, T., Lumley, T., Siscovick, D., Psaty, B. M., Zillikens, M. C., Oostra, B. A., Feitosa, M., Province, M., de Andrade, M., Turner, S. T., Schillert, A., Ziegler, A., Wild, P. S., Schnabel, R. B., Wilde, S., Munzel, T. F., Leak, T. S., Illig, T., Klopp, N., Meisinger, C., Wichmann, H-E., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F. B., Johansson, A., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Schreiber, S., Aulchenko, Y. S., Felix, J. F., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Völzke, H., Kroemer, H. K., Nauck, M., Völker, U., Polasek, O., Vitart, V., Badola, S., Parker, A. N., Ridker, P. M., Kardia, S. L. R., Blankenberg, S., Liu, Y., Curhan, G. C., Franke, A., Rochat, T., Paulweber, B., Prokopenko, I., Wang, W., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Shlipak, M. G., van Duijn, C. M., Borecki, I., Krämer, B. K., Rudan, I., Gyllensten, U., Wilson, J. F., Witteman, J. C., Pramstaller, P. P., Rettig, R., Hastie, N., Chasman, D. I., Kao, W. H., Heid, I. M. & Fox, C. S., 2010, In: Nature Genetics. 42, 5, p. 376-384 9 p.

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  • Sequencing and analysis of an Irish human genome

    Tong, P., Prendergast, J., Lohan, A. J., Farrington, S. M., Cronin, S., Friel, N., Bradley, D. G., Hardiman, O., Evans, A., Wilson, J. F. & Loftus, B., 2010, In: Genome Biology. 11, 9, p. - 14 p., R91.

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  • Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

    Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Freathy, R. M., Mook-Kanamori, D. O., Sovio, U., Prokopenko, I., Timpson, N. J., Berry, D. J., Warrington, N. M., Widen, E., Hottenga, J. J., Kaakinen, M., Lange, L. A., Bradfield, J. P., Kerkhof, M., Marsh, J. A., Mägi, R., Chen, C-M., Lyon, H. N., Kirin, M., Adair, L. S. & 31 others, Aulchenko, Y. S., Bennett, A. J., Borja, J. B., Bouatia-Naji, N., Charoen, P., Coin, L. J. M., Cousminer, D. L., de Geus, E. J. C., Deloukas, P., Elliott, P., Evans, D. M., Froguel, P., Glaser, B., Groves, C. J., Hartikainen, A-L., Hassanali, N., Hirschhorn, J. N., Hofman, A., Holly, J. M. P., Hyppönen, E., Kanoni, S., Knight, B. A., Laitinen, J., Lindgren, C. M., McArdle, W. L., O'Reilly, P. F., Pennell, C. E., Postma, D. S., Pouta, A., Ramasamy, A. & Wilson, J. F., 2010, In: Nature Genetics. 42, 5, p. 430-435 6 p.

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  • 2011

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

    Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M. & 533 others, van Bockxmeer, F. M., Waltham, M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Assimes, T. L., McPherson, R., Folkersen, L., Franco-Cereceda, A., Palmen, J., Smith, A. J., Sylvius, N., Wild, J. B., Refstrup, M., Edkins, S., Gwilliam, R., Hunt, S. E., Potter, S., Lindholt, J. S., Frikke-Schmidt, R., Tybjærg-Hansen, A., Hughes, A. E., Golledge, J., Norman, P. E., van Rij, A., Powell, J. T., Eriksson, P., Stefansson, K., Thompson, J. R., Humphries, S. E., Sayers, R. D., Deloukas, P., Samani, N. J., Schunkert, H., König, I. R., Kathiresan, S., Reilly, M. P., Assimes, T. L., Holm, H., Preuss, M., Stewart, A. F. R., Barbalic, M., Gieger, C., Absher, D., Aherrahrou, Z., Allayee, H., Altshuler, D., Anand, S. S., Andersen, K., Anderson, J. L., Ardissino, D., Ball, S. G., Balmforth, A. J., Barnes, T. A., Becker, D. M., Becker, L. C., Berger, K., Bis, J. C., Matthijs Boekholdt, S., Boerwinkle, E., Braund, P. S., Brown, M. J., Susan Burnett, M., Buysschaert, I., Carlquist, J. F., Chen, L., Cichon, S., Codd, V., Davies, R. W., Dedoussis, G., Dehghan, A., Demissie, S., Devaney, J. M., Diemert, P., Do, R., Doering, A., Eifert, S., El Mokhtari, N. E., Ellis, S. G., Elosua, R., Engert, J. C., Epstein, S. E., de Faire, U., Fischer, M., Folsom, A. R., Freyer, J., Gigante, B., Girelli, D., Gretarsdottir, S., Gudnason, V., Gulcher, J. R., Halperin, E., Hammond, N., Hazen, S. L., Hofman, A., Horne, B. D., Illig, T., Iribarren, C., Jones, G. T., Wouter Jukema, J., Kaiser, M. A., Kaplan, L. M., Kastelein, J. J. P., Khaw, K. T., Knowles, J. W., Kolovou, G., Kong, A., Laaksonen, R., Lambrechts, D., Leander, K., Lettre, G., Li, M., Lieb, W., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meisinger, C., Meitinger, T., Melander, O., Angelica Merlini, P., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Münzel, T., Musunuru, K., Nahrstaedt, J., Nelson, C. P., Nöthen, M. M., Olivieri, O., Patel, R. S., Patterson, C. C., Peters, A., Peyvandi, F., Qu, L., Quyyumi, A. A., Rader, D. J., Rallidis, L. S., Rice, C., Rosendaal, F. R., Rubin, D., Salomaa, V., Lourdes Sampietro, M., Sandhu, M. S., Schadt, E., Schäfer, A., Schillert, A., Schreiber, S., Schrezenmeir, J., Schwartz, S. M., Siscovick, D. S., Sivananthan, M., Sivapalaratnam, S., Smith, A., Smith, T. B., Snoep, J. D., Soranzo, N., Spertus, J. A., Stark, K., Stirrups, K., Stoll, M., Wilson Tang, W. H., Tennstedt, S., Thorgeirsson, G., Thorleifsson, G., Tomaszewski, M., Uitterlinden, A. G., van Rij, A. M., Voight, B. F., Wareham, N. J., Wells, G. A., Wichmann, H. E., Wild, P. S., Willenborg, C., Witteman, J. C. M., Wright, B. J., Ye, S., Zeller, T., Ziegler, A., Cambien, F., Goodall, A. H., Adrienne Cupples, L., Quertermous, T., März, W., Hengstenberg, C., Blankenberg, S., Ouwehand, W. H., Hall, A. S., Deloukas, P., Thompson, J. R., Stefansson, K., Roberts, R., Thorsteinsdottir, U., O'Donnell, C. J., McPherson, R., Erdmann, J., Samani, N. J., Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Hua Zhao, J., Heath, S. C., Eyheramendy, S., Papadakis, K., Voight, B. F., Scott, L. J., Zhang, F., Farrall, M., Tanaka, T., Wallace, C., Chambers, J. C., Khaw, K. T., Nilsson, P., van der Harst, P., Polidoro, S., Grobbee, D. E., Onland-Moret, N. C., Bots, M. L., Wain, L. V., Elliott, K. S., Teumer, A., Luan, J., Lucas, G., Kuusisto, J., Burton, P. R., Hadley, D., McArdle, W. L., Brown, M., Dominiczak, A., Newhouse, S. J., Samani, N. J., Webster, J., Zeggini, E., Beckmann, J. S., Bergmann, S., Lim, N., Song, K., Vollenweider, P., Waeber, G., Waterworth, D. M., Yuan, X., Groop, L., Orho-Melander, M., Allione, A., Di Gregorio, A., Guarrera, S., Panico, S., Ricceri, F., Romanazzi, V., Sacerdote, C., Vineis, P., Barroso, I., Sandhu, M. S., Luben, R. N., Crawford, G. J., Jousilahti, P., Perola, M., Boehnke, M., Bonnycastle, L. L., Collins, F. S., Jackson, A. U., Mohlke, K. L., Stringham, H. M., Valle, T. T., Willer, C. J., Bergman, R. N., Morken, M. A., Döring, A., Gieger, C., Illig, T., Meitinger, T., Org, E., Pfeufer, A., Wichmann, H. E., Kathiresan, S., Marrugat, J., O'Donnell, C. J., Schwartz, S. M., Siscovick, D. S., Subirana, I., Freimer, N. B., Hartikainen, A. L., McCarthy, M. I., O'Reilly, P. F., Peltonen, L., Pouta, A., de Jong, P. E., Snieder, H., van Gilst, W. H., Clarke, R., Goel, A., Hamsten, A., Peden, J. F., Seedorf, U., Syvänen, A. C., Tognoni, G., Lakatta, E. G., Sanna, S., Scheet, P., Schlessinger, D., Scuteri, A., Dörr, M., Ernst, F., Felix, S. B., Homuth, G., Lorbeer, R., Reffelmann, T., Rettig, R., Völker, U., Galan, P., Gut, I. G., Hercberg, S., Mark Lathrop, G., Zelenika, D., Deloukas, P., Soranzo, N., Williams, F. M., Zhai, G., Salomaa, V., Laakso, M., Elosua, R., Forouhi, N. G., Völzke, H., Uiterwaal, C. S., van der Schouw, Y. T., Numans, M. E., Matullo, G., Navis, G., Berglund, G., Bingham, S. A., Kooner, J. S., Connell, J. M., Bandinelli, S., Ferrucci, L., Watkins, H., Spector, T. D., Tuomilehto, J., Altshuler, D., Strachan, D. P., Laan, M., Meneton, P., Wareham, N. J., Uda, M., Jarvelin, M. R., Mooser, V., Melander, O., Loos, R. J. F., Elliott, P., Abecasis, G. R., Caulfield, M., Munroe, P. B., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., William Rayner, N., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Bragi Walters, G., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., Blair, R. D., Hill, A. A., Gerry Hill, B., Lewis, D. R., McNoe, L. A., Merriman, T. R., Naik, D. K., Vicky Phillips, L., Thomson, I. A., Topless, R., Vasudevan, T. M. & Yu, G., 11 Nov 2011, In: American Journal of Human Genetics. 89, 5, p. 619-627 9 p.

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  • Abundant Pleiotropy in Human Complex Diseases and Traits

    Sivakumaran, S., Agakov, F., Theodoratou, E., Prendergast, J. G., Zgaga, L., Manolio, T., Rudan, I., McKeigue, P., Wilson, J. F. & Campbell, H., Nov 2011, In: American Journal of Human Genetics. 89, 5, p. 607-618 12 p.

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  • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

    International Lung Cancer Consortium, Soler Artigas, M., Loth, D. W., Wain, L. V., Gharib, S. A., Obeidat, M., Tang, W., Zhai, G., Zhao, J. H., Smith, A. V., Huffman, J. E., Albrecht, E., Jackson, C. M., Evans, D. M., Cadby, G., Fornage, M., Manichaikul, A., Lopez, L. M., Johnson, T., Aldrich, M. C. & 31 others, Aspelund, T., Barroso, I., Campbell, H., Cassano, P. A., Couper, D. J., Eiriksdottir, G., Franceschini, N., Garcia, M., Gieger, C., Gislason, G. K., Grkovic, I., Hammond, C. J., Hancock, D. B., Harris, T. B., Ramasamy, A., Heckbert, S. R., Deary, I. J., Harris, S. E., Henderson, J., Hunter, M. L., Kerr, S. M., Morris, A., Porteous, D. J., Starr, J. M., Rudan, I., Vitart, V., Wild, S. H., Wright, A. F., Zgaga, L., Wilson, J. F. & Hayward, C., Nov 2011, In: Nature Genetics. 43, 11, p. 1082-90 9 p.

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  • Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    AortaGen Consortium, CardioGram, KidneyGen Consortium, CKDGen Consortium, CHARGE Consortium Heart Failure, EchoGen Consortium, Cardiogenics Consortium, LifeLines Cohort Study, Wain, L. V., Verwoert, G. C., O'Reilly, P. F., Shi, G., Johnson, T., Johnson, A. D., Bochud, M., Rice, K. M., Henneman, P., Smith, A. V., Ehret, G. B., Amin, N., Larson, M. G., Mooser, V., Hadley, D., Doerr, M., Bis, J. C., Aspelund, T., Esko, T. & 31 others, Janssens, A. C. J. W., Zhao, J. H., Heath, S., Laan, M., Fu, J., Pistis, G., Luan, J., Arora, P., Lucas, G., Pirastu, N., Pichler, I., Jackson, A. U., Webster, R. J., Zhang, F., Peden, J. F., Schmidt, H., Tanaka, T., Campbell, H., Igl, W., Milaneschi, Y., Hottenga, J-J., Vitart, V., Lopez, L. M., Navarro, P., Wild, S. H., Davies, G., Starr, J., Rudan, I., Hayward, C., Deary, I. J. & Wilson, J. F., Oct 2011, In: Nature Genetics. 43, 10, p. 1005-11 7 p.

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  • Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults

    Huffman, J. E., Knezevic, A., Vitart, V., Kattla, J., Adamczyk, B., Novokmet, M., Igl, W., Pucic, M., Zgaga, L., Johannson, Å., Redzic, I., Gornik, O., Zemunik, T., Polasek, O., Kolcic, I., Pehlic, M., Koeleman, C. A. M., Campbell, S., Wild, S. H., Hastie, N. D. & 9 others, Campbell, H., Gyllensten, U., Wuhrer, M., Wilson, J. F., Hayward, C., Rudan, I., Rudd, P. M., Wright, A. F. & Lauc, G., 9 Sep 2011, In: Human Molecular Genetics. 20, 24, p. 5000-11 12 p.

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  • Characterisation of Genome-Wide Association Epistasis Signals for Serum Uric Acid in Human Population Isolates

    Wei, W., Hemani, G., Hicks, A. A., Vitart, V., Cabrera-Cardenas, C., Navarro, P., Huffman, J., Hayward, C., Knott, S. A., Rudan, I., Pramstaller, P. P., Wild, S. H., Wilson, J. F., Campbell, H., Dunlop, M. G., Hastie, N., Wright, A. F. & Haley, C. S., 19 Aug 2011, In: PLoS ONE. 6, 8, e23836.

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  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

    Kilpeläinen, T. O., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., Styrkarsdottir, U., Zhou, Y., Smith, A. V., Zhao, J-H., Amin, N., Vedantam, S., Shin, S-Y., Haritunians, T., Fu, M., Feitosa, M. F. & 97 others, Kumari, M., Halldorsson, B. V., Tikkanen, E., Mangino, M., Hayward, C., Song, C., Arnold, A. M., Aulchenko, Y. S., Oostra, B. A., Campbell, H., Cupples, L. A., Davis, K. E., Döring, A., Eiriksdottir, G., Estrada, K., Fernández-Real, J. M., Garcia, M., Gieger, C., Glazer, N. L., Guiducci, C., Hofman, A., Humphries, S. E., Isomaa, B., Jacobs, L. C., Jula, A., Karasik, D., Karlsson, M. K., Khaw, K-T., Kim, L. J., Kivimäki, M., Klopp, N., Kühnel, B., Kuusisto, J., Liu, Y., Ljunggren, O., Lorentzon, M., Luben, R. N., McKnight, B., Mellström, D., Mitchell, B. D., Mooser, V., Moreno, J. M., Männistö, S., O'Connell, J. R., Pascoe, L., Peltonen, L., Peral, B., Perola, M., Psaty, B. M., Salomaa, V., Savage, D. B., Semple, R. K., Skaric-Juric, T., Sigurdsson, G., Song, K. S., Spector, T. D., Syvänen, A-C., Talmud, P. J., Thorleifsson, G., Thorsteinsdottir, U., Uitterlinden, A. G., van Duijn, C. M., Vidal-Puig, A., Wild, S. H., Wright, A. F., Clegg, D. J., Schadt, E., Wilson, J. F., Rudan, I., Ripatti, S., Borecki, I. B., Shuldiner, A. R., Ingelsson, E., Jansson, J-O., Kaplan, R. C., Gudnason, V., Harris, T. B., Groop, L., Kiel, D. P., Rivadeneira, F., Walker, M., Barroso, I., Vollenweider, P., Waeber, G., Chambers, J. C., Kooner, J. S., Soranzo, N., Hirschhorn, J. N., Stefansson, K., Wichmann, H-E., Ohlsson, C., O'Rahilly, S., Wareham, N. J., Speliotes, E. K., Fox, C. S., Laakso, M. & Loos, R. J. F., Aug 2011, In: Nature Genetics. 43, 8, p. 753-760 8 p.

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  • The case for launch of an international DNA-based birth cohort study

    Rudan, I., Chopra, M., Aulchenko, Y., Baqui, A. H., Bhutta, Z. A., Edmond, K., Horta, B. L., Klugman, K. P., Lanata, C. F., Madhi, S. A., Nair, H., Qureshi, Z., Rubens, C., Theodoratou, E., Victora, C. G., Wang, W., Weber, M. W., Wilson, J. F., Zgaga, L. & Campbell, H., Jun 2011, In: Journal of Global Health. 1, 1, p. 39-45 7 p.

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  • Does inbreeding affect N-glycosylation of human plasma proteins?

    Polasek, O., Leutenegger, A-L., Gornik, O., Zgaga, L., Kolcic, I., McQuillan, R., Wilson, J. F., Hayward, C., Wright, A., Lauc, G., Campbell, H. & Rudan, I., May 2011, In: Molecular genetics and genomics. 285, 5, p. 427-432 6 p.

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  • Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults

    Smith, N. L., Huffman, J. E., Strachan, D. P., Huang, J., Dehghan, A., Trompet, S., Lopez, L. M., Shin, S-Y., Baumert, J., Vitart, V., Bis, J. C., Wild, S. H., Rumley, A., Yang, Q., Uitterlinden, A. G., Stott, D. J., Davies, G., Carter, A. M., Thorand, B., Polašek, O. & 46 others, McKnight, B., Campbell, H., Rudnicka, A. R., Chen, M-H., Buckley, B. M., Harris, S. E., Peters, A., Pulanic, D., Lumley, T., de Craen, A. J. M., Liewald, D. C., Gieger, C., Campbell, S., Ford, I., Gow, A. J., Luciano, M., Porteous, D. J., Guo, X., Sattar, N., Tenesa, A., Cushman, M., Slagboom, P. E., Visscher, P. M., Spector, T. D., Illig, T., Rudan, I., Bovill, E. G., Wright, A. F., McArdle, W. L., Tofler, G., Hofman, A., Westendorp, R. G. J., Starr, J. M., Grant, P. J., Karakas, M., Hastie, N. D., Psaty, B. M., Wilson, J. F., Lowe, G. D. O., O'Donnell, C. J., Witteman, J. C. M., Jukema, J. W., Deary, I. J., Soranzo, N., Koenig, W. & Hayward, C., Apr 2011, In: Circulation. 123, 17, p. 1864-1872 9 p.

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  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (vol 42, pg 579, 2010)

    GIANT Consortium, MAGIC Investigators, Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C. & 31 others, Hofmann, O. M., Dupuis, J., Qi, L., Segre, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostroem, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Morris, A., Rudan, I., Campbell, H. & Wilson, J. F., Apr 2011, In: Nature Genetics. 43, 4, p. 388-388 1 p.

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  • Erratum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 138 others, Dupuis, J., Qi, L., Segŕ, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrám, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., J́rgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proeńa, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsa̧, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M. & McCarthy, M. I., 29 Mar 2011, In: Nature Genetics. 43, 4

    Research output: Contribution to journalArticlepeer-review

  • A combined long-range phasing and long haplotype imputation method to impute phase for SNP genotypes

    Hickey, J., Kinghorn, B. P., Tier, B., Wilson, J. F., Dunstan, N. & van der Werf, J. H. J., Mar 2011, In: Genetics Selection Evolution. 43, 13 p., 12.

    Research output: Contribution to journalArticlepeer-review

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  • Meta-Analysis of Genome-Wide Association Studies in > 80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

    Dehghan, A., Dupuis, J., Barbalic, M., Bis, J. C., Eiriksdottir, G., Lu, C., Pellikka, N., Wallaschofski, H., Kettunen, J., Henneman, P., Baumert, J., Strachan, D. P., Fuchsberger, C., Vitart, V., Wilson, J. F., Pare, G., Naitza, S., Rudock, M. E., Surakka, I., de Geus, E. J. C. & 94 others, Alizadeh, B. Z., Guralnik, J., Shuldiner, A., Tanaka, T., Zee, R. Y. L., Schnabel, R. B., Nambi, V., Kavousi, M., Ripatti, S., Nauck, M., Smith, N. L., Smith, A. V., Sundvall, J., Scheet, P., Liu, Y., Ruokonen, A., Rose, L. M., Larson, M. G., Hoogeveen, R. C., Freimer, N. B., Teumer, A., Tracy, R. P., Launer, L. J., Buring, J. E., Yamamoto, J. F., Folsom, A. R., Sijbrands, E. J. G., Pankow, J., Elliott, P., Keaney, J. F., Sun, W., Sarin, A-P., Fontes, J. D., Badola, S., Astor, B. C., Hofman, A., Pouta, A., Werdan, K., Greiser, K. H., Kuss, O., Schwabedissen, H. E. M. Z., Thiery, J., Jamshidi, Y., Nolte, I. M., Soranzo, N., Spector, T. D., Voelzke, H., Parker, A. N., Aspelund, T., Bates, D., Young, L., Tsui, K., Siscovick, D. S., Guo, X., Rotter, J. I., Uda, M., Schlessinger, D., Rudan, I., Hicks, A. A., Penninx, B. W., Thorand, B., Gieger, C., Coresh, J., Willemsen, G., Harris, T. B., Uitterlinden, A. G., Jaervelin, M-R., Rice, K., Radke, D., Salomaa, V., van Dijk, K. W., Boerwinkle, E., Vasan, R. S., Ferrucci, L., Gibson, Q. D., Bandinelli, S., Snieder, H., Boomsma, D. I., Xiao, X., Campbell, H., Hayward, C., Pramstaller, P. P., van Duijn, C. M., Peltonen, L., Psaty, B. M., Gudnason, V., Ridker, P. M., Homuth, G., Koenig, W., Ballantyne, C. M., Witteman, J. C. M., Benjamin, E. J., Perola, M. & Chasman, D. I., 22 Feb 2011, In: Circulation. 123, 7, p. 731-U151 91 p.

    Research output: Contribution to journalArticlepeer-review

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  • A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

    SpiroMeta Consortium, Obeidat, M., Wain, L. V., Shrine, N., Kalsheker, N., Soler Artigas, M., Repapi, E., Burton, P. R., Johnson, T., Ramasamy, A., Zhao, J. H., Zhai, G., Huffman, J. E., Vitart, V., Albrecht, E., Igl, W., Hartikainen, A-L., Pouta, A., Cadby, G., Hui, J. & 31 others, Palmer, L. J., Hadley, D., McArdle, W. L., Rudnicka, A. R., Barroso, I., Loos, R. J. F., Wareham, N. J., Mangino, M., Soranzo, N., Spector, T. D., Gläser, S., Homuth, G., Völzke, H., Deloukas, P., Granell, R., Henderson, J., Grkovic, I., Jankovic, S., Zgaga, L., Polašek, O., Rudan, I., Wright, A. F., Campbell, H., Wild, S. H., Wilson, J. F., Heinrich, J., Imboden, M., Probst-Hensch, N. M., Gyllensten, U., Johansson, Å. & Hayward, C., 2011, In: PLoS ONE. 6, 5, p. e19382

    Research output: Contribution to journalArticlepeer-review

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  • A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

    ENGAGE Consortium, Surakka, I., Isaacs, A., Karssen, L. C., Laurila, P-P. P., Middelberg, R. P. S., Tikkanen, E., Ried, J. S., Lamina, C., Mangino, M., Igl, W., Hottenga, J-J., Lagou, V., van der Harst, P., Mateo Leach, I., Esko, T., Kutalik, Z., Wainwright, N. W., Struchalin, M. V., Sarin, A-P. & 31 others, Kangas, A. J., Viikari, J. S., Perola, M., Rantanen, T., Petersen, A-K., Soininen, P., Johansson, A., Soranzo, N., Heath, A. C., Papamarkou, T., Prokopenko, I., Tönjes, A., Kronenberg, F., Döring, A., Rivadeneira, F., Montgomery, G. W., Whitfield, J. B., Kähönen, M., Lehtimäki, T., Freimer, N. B., Willemsen, G., de Geus, E. J. C., Palotie, A., Sandhu, M. S., Waterworth, D. M., Metspalu, A., Stumvoll, M., Uitterlinden, A. G., Wilson, J. F., Rudan, I. & Campbell, H., 2011, In: PLoS Genetics. 7, 10, p. e1002333

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  • Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

    International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Fox, E. R., Young, J. H., Li, Y., Dreisbach, A. W., Keating, B. J., Musani, S. K., Liu, K., Morrison, A. C., Ganesh, S., Kutlar, A., Ramachandran, V. S., Polak, J. F., Fabsitz, R. R., Dries, D. L., Farlow, D. N., Redline, S., Adeyemo, A., Hirschorn, J. N., Sun, Y. V. & 31 others, Wyatt, S. B., Penman, A. D., Palmas, W., Rotter, J. I., Townsend, R. R., Doumatey, A. P., Tayo, B. O., Mosley, T. H., Lyon, H. N., Kang, S. J., Rotimi, C. N., Cooper, R. S., Franceschini, N., Curb, J. D., Martin, L. W., Eaton, C. B., Kardia, S. L. R., Taylor, H. A., Caulfield, M. J., Ehret, G. B., Johnson, T., Chakravarti, A., Zhu, X., Levy, D., Wild, S. H., Rudan, I., Vitart, V., Campbell, H., Hayward, C., Wright, A. F. & Wilson, J. F., 2011, In: Human Molecular Genetics. 20, 11, p. 2273-84 12 p.

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  • Copy number variation across European populations

    Chen, W., Hayward, C., Wright, A. F., Hicks, A. A., Vitart, V., Knott, S., Wild, S. H., Pramstaller, P. P., Wilson, J. F., Rudan, I. & Porteous, D. J., 2011, In: PLoS ONE. 6, 8, p. e23087

    Research output: Contribution to journalArticlepeer-review

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  • Genetic architecture of circulating lipid levels

    ENGAGE CONSORTIUM, Demirkan, A., Amin, N., Isaacs, A., Jarvelin, M-R., Whitfield, J. B., Wichmann, H-E., Kyvik, K. O. H. M., Rudan, I., Gieger, C., Hicks, A. A., Johansson, Å., Hottenga, J-J., Smith, J. J., Wild, S. H., Pedersen, N. L., Willemsen, G., Mangino, M., Hayward, C., Uitterlinden, A. G. & 27 others, Hofman, A., Witteman, J., Montgomery, G. W., Pietiläinen, K. H., Rantanen, T., Kaprio, J., Döring, A., Pramstaller, P. P., Gyllensten, U., de Geus, E. J. C., Penninx, B. W., Wilson, J. F., Rivadeneria, F., Magnusson, P. K. E., Boomsma, D. I., Spector, T., Campbell, H., Hoehne, B., Martin, N. G., Oostra, B. A., McCarthy, M., Peltonen-Palotie, L., Aulchenko, Y., Visscher, P. M., Ripatti, S., Janssens, A. C. J. W. & van Duijn, C. M., 2011, In: European Journal of Human Genetics. 19, 7, p. 813-9 7 p.

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  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret, G. B., Munroe, P. B., Rice, K. M., Bochud, M., Johnson, A. D., Chasman, D. I., Smith, A. V., Tobin, M. D., Verwoert, G. C., Hwang, S-J., Pihur, V., Vollenweider, P., O'Reilly, P. F., Amin, N., Bragg-Gresham, J. L., Teumer, A., Glazer, N. L., Launer, L., Zhao, J. H. & 31 others, Aulchenko, Y., Heath, S., Sõber, S., Parsa, A., Luan, J., Arora, P., Dehghan, A., Zhang, F., Lucas, G., Hicks, A. A., Jackson, A. U., Peden, J. F., Tanaka, T., Wild, S. H., Rudan, I., Igl, W., Milaneschi, Y., Parker, A. N., Fava, C., Chambers, J. C., Fox, E. R., Kumari, M., Go, M. J., van der Harst, P., Kao, W. H. L., Sjögren, M., Vitart, V., Campbell, H., Hayward, C., Wright, A. F. & Wilson, J. F., 2011, In: Nature. 478, 7367, p. 103-109 7 p.

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  • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    DIAGRAM Consortium, GIANT Consortium, Morris, A., Rudan, I., Campbell, H. & Wilson, J., 2011, In: Diabetes . 60, 10, p. 2624-34 11 p.

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  • Glycomics meets lipidomics--associations of N-glycans with classical lipids, glycerophospholipids, and sphingolipids in three European populations

    Igl, W., Polasek, O., Gornik, O., Knezevic, A., Pucic, M., Novokmet, M., Huffman, J., Gnewuch, C., Liebisch, G., Rudd, P. M., Campbell, H., Wilson, J. F., Rudan, I., Gyllensten, U., Schmitz, G. & Lauc, G., 2011, In: Molecular BioSystems. 7, 6, p. 1852-1862 11 p.

    Research output: Contribution to journalArticlepeer-review

  • High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations

    Pucić, M., Knezević, A., Vidic, J., Adamczyk, B., Novokmet, M., Polasek, O., Gornik, O., Supraha-Goreta, S., Wormald, M. R., Redzić, I., Campbell, H., Wright, A., Hastie, N. D., Wilson, J. F., Rudan, I., Wuhrer, M., Rudd, P. M., Josić, D. & Lauc, G., 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.010090

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  • Identity-by-descent-based phasing and imputation in founder populations using graphical models

    Palin, K., Campbell, H., Wright, A. F., Wilson, J. F. & Durbin, R., 2011, In: Genetic Epidemiology. 35, 8, p. 853-60 8 p.

    Research output: Contribution to journalArticlepeer-review

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  • Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

    CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., Markus, H. S., Schmidt, R., Huffman, J. E., Lehtimäki, T., Baumert, J., Münzel, T., Heckbert, S. R., Dehghan, A., North, K., Oostra, B. & 31 others, Bevan, S., Stoegerer, E-M., Hayward, C., Raitakari, O., Meisinger, C., Schillert, A., Sanna, S., Völzke, H., Cheng, Y-C., Thorsson, B., Fox, C. S., Rice, K., Rivadeneira, F., Nambi, V., Halperin, E., Petrovic, K. E., Peltonen, L., Wichmann, H. E., Schnabel, R. B., Dörr, M., Parsa, A., Aspelund, T., Demissie, S., Kathiresan, S., Reilly, M. P., Taylor, K., Uitterlinden, A., Couper, D. J., Sitzer, M., Kähönen, M. & Wilson, J. F., 2011, In: Nature Genetics. 43, 10, p. 940-7 8 p.

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  • Runs of homozygosity do not influence survival to old age

    Kuningas, M., McQuillan, R., Wilson, J. F., Hofman, A., van Duijn, C. M., Uitterlinden, A. G. & Tiemeier, H., 2011, In: PLoS ONE. 6, 7, p. e22580

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  • Variants in STAT5B associate with serum TC and LDL-C levels

    Kornfeld, J-W., Isaacs, A., Vitart, V., Pospisilik, J. A., Meitinger, T., Gyllensten, U., Wilson, J. F., Rudan, I., Campbell, H., Penninger, J. M., Sexl, V., Moriggl, R., van Duijn, C., Pramstaller, P. P. & Hicks, A. A., 2011, In: Journal of Clinical Endocrinology & Metabolism. 96, 9, p. E1496-501

    Research output: Contribution to journalArticlepeer-review

  • 2012

    Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

    CARDIoGRAM Consortium, Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A. & 31 others, Liu, C-T., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M. F., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Tönjes, A., Dehghan, A., Lambert, J-C., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Zgaga, L., Wild, S. H., Wright, A. F., Campbell, H., Hastie, N., Vitart, V., Colhoun, H., Rudan, I., Wilson, J. F. & Hayward, C., 15 Dec 2012, In: Human Molecular Genetics. 21, 24, p. 5329-5343 15 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide meta-analysis of common variant differences between men and women

    Wellcome Trust Case Control Consortium, Boraska, V., Jerončić, A., Colonna, V., Southam, L., Nyholt, D. R., Rayner, N. W., Perry, J. R. B., Toniolo, D., Albrecht, E., Ang, W., Bandinelli, S., Barbalic, M., Barroso, I., Beckmann, J. S., Biffar, R., Boomsma, D., Campbell, H., Corre, T., Erdmann, J. & 31 others, Esko, T., Fischer, K., Franceschini, N., Frayling, T. M., Girotto, G., Gonzalez, J. R., Harris, T. B., Heath, A. C., Heid, I. M., Hoffmann, W., Hofman, A., Horikoshi, M., Zhao, J. H., Jackson, A. U., Hottenga, J-J., Jula, A., Kähönen, M., Khaw, K-T., Kiemeney, L. A., Klopp, N., Kutalik, Z., Lagou, V., Launer, L. J., Lehtimäki, T., Lemire, M., Pirastu, N., Wright, A. F., Zgaga, L., Hayward, C., Wilson, J. F. & Rudan, I., Nov 2012, In: Human Molecular Genetics. 21, 21, p. 4805-15 11 p.

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  • Localising Loci underlying Complex Trait Variation Using Regional Genomic Relationship Mapping

    Nagamine, Y., Pong-Wong, R., Navarro, P., Vitart, V., Hayward, C., Rudan, I., Campbell, H., Wilson, J., Wild, S., Hicks, A. A., Pramstaller, P. P., Hastie, N., Wright, A. F. & Haley, C. S., Oct 2012, In: PLoS ONE. 7, 10, 12 p., e46501.

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  • Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene

    EUROSPAN Consortium, Johansson, A., Marroni, F., Hayward, C., Franklin, C. S., Kirichenko, A. V., Jonasson, I., Hicks, A. A., Vitart, V., Isaacs, A., Axenovich, T., Campbell, S., Floyd, J., Hastie, N., Knott, S., Lauc, G., Pichler, I., Rotim, K., Wild, S. H., Zorkoltseva, I. V. & 10 others, Wilson, J. F., Rudan, I., Campbell, H., Pattaro, C., Pramstaller, P., Oostra, B. A., Wright, A. F., van Duijn, C. M., Aulchenko, Y. S. & Gyllensten, U., 6 Sep 2012, In: Obesity. 18, 4, p. 803-8 6 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association uncovers shared genetic effects among personality traits and mood states

    Luciano, M., Huffman, J. E., Arias-Vásquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G., Zgaga, L., Janzing, J., Ke, X., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J-J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N. D., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 1 Sep 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

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  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    DIAbet Genetics Replication, Asian Genetic Epidemiology, Genetic Invest ANthropometric, Meta-Anal Glucose Insulin-Related, S Asian Type 2 Diabet SAT2D, Wellcome Trust Case Control, Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segre, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H. M., Dina, C., Esko, T., Fraser, R. M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C. & 31 others, Luan, J., Lindgren, C. M., Mueller-Nurasyid, M., Pechlivanis, S., Rayner, N. W., Scott, L. J., Wiltshire, S., Yengo, L., Kinnunen, L., Rossin, E. J., Raychaudhuri, S., Johnson, A. D., Dimas, A. S., Loos, R. J. F., Vedantam, S., Chen, H., Florez, J. C., Fox, C., Liu, C-T., Rybin, D., Couper, D. J., Kao, W. H. L., Li, M., Cornelis, M. C., Kraft, P., Sun, Q., van Dam, R. M., Campbell, H., Price, J. F., Wilson, J. F. & Morris, A., Sep 2012, In: Nature Genetics. 44, 9, p. 981-90 10 p.

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  • Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

    Verhoeven, V. J. M., Hysi, P. G., Saw, S-M., Vitart, V., Mirshahi, A., Guggenheim, J. A., Cotch, M. F., Yamashiro, K., Baird, P. N., Mackey, D. A., Wojciechowski, R., Ikram, M. K., Hewitt, A. W., Duggal, P., Janmahasatian, S., Khor, C-C., Fan, Q., Zhou, X., Young, T. L., Tai, E-S. & 75 others, Goh, L-K., Li, Y-J., Aung, T., Vithana, E., Teo, Y-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A. F., Polasek, O., Campbell, H., Wilson, J. F., Fleck, B. W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St Pourcain, B., Lu, Y., Rahi, J. S., Cumberland, P. M., Bhattacharya, S., Simpson, C. L., Atwood, L. D., Li, X., Raffel, L. J., Murgia, F., Portas, L., Despriet, D. D. G., van Koolwijk, L. M. E., Wolfram, C., Lackner, K. J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B. E., Meitinger, T., Spector, T. D., Oostra, B. A., Smith, A. V., de Jong, P. T. V. M., Hofman, A., Amin, N., Karssen, L. C., Rivadeneira, F., Vingerling, J. R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A. G., Williams, C., Zeller, T., Castagné, R., Oexle, K., van Duijn, C. M., Iyengar, S. K., Mitchell, P., Wang, J. J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J. E., Stambolian, D., Wong, T-Y., Hammond, C. J. & Klaver, C. C. W., Sep 2012, In: Human Genetics. 131, 9, p. 1467-80 14 p.

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  • Uncovering Networks from Genome-Wide Association Studies via Circular Genomic Permutation

    Cabrera, C. P., Navarro, P., Huffman, J. E., Wright, A. F., Hayward, C., Campbell, H., Wilson, J. F., Rudan, I., Hastie, N. D., Vitart, V. & Haley, C. S., Sep 2012, In: G3: Genes | Genomes | Genetics. 2, 9, p. 1067-75 9 p.

    Research output: Contribution to journalArticlepeer-review

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  • A new prevalence study of multiple sclerosis in Orkney, Shetland and Aberdeen city

    Visser, E. M., Wilde, K., Wilson, J. F., Yong, K. K. & Counsell, C. E., Jul 2012, In: Journal of Neurology, Neurosurgery & Psychiatry. 83, 7, p. 719-724 6 p.

    Research output: Contribution to journalArticlepeer-review

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

    MUTHER Consortium, DIAGRAM Consortium, Manning, A. K., Hivert, M-F., Scott, R. A., Grimsby, J. L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C-T., Bielak, L. F., Prokopenko, I., Amin, N., Barnes, D., Cadby, G., Hottenga, J-J., Ingelsson, E., Jackson, A. U., Johnson, T., Kanoni, S., Ladenvall, C. & 31 others, Lagou, V., Lahti, J., Lecoeur, C., Liu, Y., Martinez-Larrad, M. T., Montasser, M. E., Navarro, P., Perry, J. R. B., Rasmussen-Torvik, L. J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R. J., Tanaka, T., van Duijn, C. M., An, P., de Andrade, M., Andrews, J. S., Aspelund, T., Atalay, M., Aulchenko, Y., Balkau, B., Bandinelli, S., Campbell, H., Hayward, C., Rudan, I., Vitart, V., Wild, S. H., Wilson, J. F., Wright, A. F. & Zgaga, L., Jun 2012, In: Nature Genetics. 44, 6, p. 659-U81 13 p.

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  • Genetic adaptation of fatty-acid metabolism: A human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

    Ameur, A., Enroth, S., Johansson, A., Zaboli, G., Igl, W., Johansson, A. C. V., Rivas, M. A., Daly, M. J., Schmitz, G., Hicks, A. A., Meitinger, T., Feuk, L., van Duijn, C., Oostra, B., Pramstaller, P. P., Rudan, I., Wright, A. F., Wilson, J. F., Campbell, H. & Gyllensten, U., 4 May 2012, In: American Journal of Human Genetics. 90, 5, p. 809-820 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Common variants at 6q22 and 17q21 are associated with intracranial volume

    Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genomic Ep, Ikram, M. A., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R. & 31 others, Rivadeneira, F., Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G. & Wilson, J. F., May 2012, In: Nature Genetics. 44, 5, p. 539-+ 7 p.

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  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

    Estrada, K., Styrkarsdottir, U., Evangelou, E., Hsu, Y-H., Duncan, E. L., Ntzani, E. E., Oei, L., Albagha, O. M. E., Amin, N., Kemp, J. P., Koller, D. L., Li, G., Liu, C-T., Minster, R. L., Moayyeri, A., Vandenput, L., Willner, D., Xiao, S-M., Yerges-Armstrong, L. M., Zheng, H-F. & 161 others, Alonso, N., Eriksson, J., Kammerer, C. M., Kaptoge, S. K., Leo, P. J., Thorleifsson, G., Wilson, S. G., Wilson, J. F., Aalto, V., Alen, M., Aragaki, A. K., Aspelund, T., Center, J. R., Dailiana, Z., Duggan, D. J., Garcia, M., Garcia-Giralt, N., Giroux, S., Hallmans, G., Hocking, L. J., Husted, L. B., Jameson, K. A., Khusainova, R., Kim, G. S., Kooperberg, C., Koromila, T., Kruk, M., Laaksonen, M., Lacroix, A. Z., Lee, S. H., Leung, P. C., Lewis, J. R., Masi, L., Mencej-Bedrac, S., Nguyen, T. V., Nogues, X., Patel, M. S., Prezelj, J., Rose, L. M., Scollen, S., Siggeirsdottir, K., Smith, A. V., Svensson, O., Trompet, S., Trummer, O., van Schoor, N. M., Woo, J., Zhu, K., Balcells, S., Brandi, M. L., Buckley, B. M., Cheng, S., Christiansen, C., Cooper, C., Dedoussis, G., Ford, I., Frost, M., Goltzman, D., González-Macías, J., Kähönen, M., Karlsson, M., Khusnutdinova, E., Koh, J-M., Kollia, P., Langdahl, B. L., Leslie, W. D., Lips, P., Ljunggren, Ö., Lorenc, R. S., Marc, J., Mellström, D., Obermayer-Pietsch, B., Olmos, J. M., Pettersson-Kymmer, U., Reid, D. M., Riancho, J. A., Ridker, P. M., Rousseau, F., Slagboom, P. E., Tang, N. L. S., Urreizti, R., Van Hul, W., Viikari, J., Zarrabeitia, M. T., Aulchenko, Y. S., Castano-Betancourt, M., Grundberg, E., Herrera, L., Ingvarsson, T., Johannsdottir, H., Kwan, T., Li, R., Luben, R., Medina-Gómez, C., Palsson, S. T., Reppe, S., Rotter, J. I., Sigurdsson, G., van Meurs, J. B. J., Verlaan, D., Williams, F. M. K., Wood, A., Zhou, Y., Gautvik, K. M., Pastinen, T., Raychaudhuri, S., Cauley, J. A., Chasman, D. I., Clark, G. R., Cummings, S. R., Danoy, P., Dennison, E. M., Eastell, R., Eisman, J. A., Gudnason, V., Hofman, A., Jackson, R. D., Jones, G., Jukema, J. W., Khaw, K-T., Lehtimäki, T., Liu, Y., Lorentzon, M., McCloskey, E., Mitchell, B. D., Nandakumar, K., Nicholson, G. C., Oostra, B. A., Peacock, M., Pols, H. A. P., Prince, R. L., Raitakari, O., Reid, I. R., Robbins, J., Sambrook, P. N., Sham, P. C., Shuldiner, A. R., Tylavsky, F. A., van Duijn, C. M., Wareham, N. J., Cupples, L. A., Econs, M. J., Evans, D. M., Harris, T. B., Kung, A. W. C., Psaty, B. M., Reeve, J., Spector, T. D., Streeten, E. A., Zillikens, M. C., Thorsteinsdottir, U., Ohlsson, C., Karasik, D., Richards, J. B., Brown, M. A., Stefansson, K., Uitterlinden, A. G., Ralston, S. H., Ioannidis, J. P. A., Kiel, D. P. & Rivadeneira, F., May 2012, In: Nature Genetics. 44, 5, p. 491-501 11 p.

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  • Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases

    GIANT Consortium, DIAGRAM Consortium, MAGIC, Perry, J. R. B., Voight, B. F., Yengo, L., Amin, N., Dupuis, J., Ganser, M., Grallert, H., Navarro, P., Li, M., Qi, L., Steinthorsdottir, V., Scott, R. A., Almgren, P., Arking, D. E., Aulchenko, Y., Balkau, B., Benediktsson, R., Bergman, R. N., Boerwinkle, E. & 31 others, Bonnycastle, L., Burtt, N. P., Campbell, H., Charpentier, G., Collins, F. S., Gieger, C., Green, T., Hadjadj, S., Hattersley, A. T., Herder, C., Hofman, A., Johnson, A. D., Kottgen, A., Kraft, P., Labrune, Y., Langenberg, C., Manning, A. K., Mohlke, K. L., Morris, A. P., Oostra, B., Pankow, J., Petersen, A-K., Pramstaller, P. P., Prokopenko, I., Rathmann, W., Rayner, W., Roden, M., Rudan, I., Wright, A. F., Wilson, J. F. & Morris, A., May 2012, In: PLoS Genetics. 8, 5, p. 1-14 14 p., e1002741.

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  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

    Stolk, L., Zillikens, M. C., Uitterlinden, A. G., Visser, J. A., Hofman, A., Van Duijn, C. M., Perry, J. R. B., Melzer, D., Murray, A., Chasman, D. I., Paré, G., Buring, J. E., Crisponi, L., Ridker, P. M., He, C., Mangino, M., Zhai, G., Burri, A., Soranzo, N., Spector, T. D. & 159 others, Sulem, P., Gudbjartsson, D. F., Stacey, S. N., Styrkarsdottir, U., Stefansson, K., Thorsteinsdottir, U., Barbalic, M., Boerwinkle, E., Broer, L., Van Wingerden, S., Janssens, A. C. J. W., Byrne, E. M., Martin, N. G., Medland, S. E., Nyholt, D. R., Montgomery, G. W., Ernst, F., Esko, T., Fischer, K., Haller, T., Hass, M., Salumets, A., Metspalu, A., Völzke, H., Franceschini, N., Hottenga, J-J., De Geus, E. J. C., Vink, J. M., Willemsen, G., Boomsma, D. I., Kraft, P., Chen, C., Hankinson, S. E., Hu, F. B., Hunter, D. J., McArdle, P. F., Yerges-Armstrong, L. M., Streeten, E. A., Porcu, E., Ferreli, L., Lai, S., Marongiu, M., Sanna, S., Uda, M., Shin, S-Y., Deloukas, P., Palotie, A., Stirrups, K., Smith, A. V., Aspelund, T., Eiriksdottir, G., Emilsson, V., Gudnason, V., Tryggvadottir, L., Zhuang, W. V., Lunetta, K. L., Albrecht, E., Gieger, C., Alizadeh, B. Z., Snieder, H., Stolk, R. P., Bandinelli, S., Lauc, L. B., Beckmann, J. S., Kutalik, Z., Boban, M., Kolcic, I., Polasek, O., Rudan, I., Zemunik, T., Broekmans, F. J., Fauser, B. C. J. M., Voorhuis, M., Campbell, H., Wilson, J. F., Zgaga, L., Chanock, S. J., Cornelis, M. C., Van Dam, R. M., Corre, T., Masciullo, C., Pistis, G., Sala, C., Toniolo, D., Coviello, A. D., Glazer, N., Murabito, J. M., Johnson, A. D., Karasik, D., Kiel, D. P., D'Adamo, P., Gasparini, P., Ulivi, S., Davies, G., Deary, I. J., Lopez, L. M., De Faire, U., Starr, J. M., Visscher, P. M., Dedoussis, G. V. Z., Stathopoulou, M. G., Ebrahim, S., Eriksson, J. G., Demerath, E. W., Ferrucci, L., Folsom, A. R., Garcia, M. E., Harris, T. B., Launer, L. J., Grobbee, D. E., Onland-Moret, N. C., Peeters, P. H. M., Van Der Schouw, Y. T., Van Gils, C. H., Hall, P., Ingelsson, E., Magnusson, P. K. E., Pedersen, N. L., Rehnberg, E., Hayward, C., Navarro, P., Tenesa, A., Wright, A. F., Heath, A. C., Kardia, S. L. R., Smith, J. A., Keyzer, J., Lahti, J., R Currency Signikkönen, K., Laisk, T., Laven, J. S. E., Louwers, Y. V., Lawlor, D. A., Liu, J., Klaric, I. M., McKnight, B., Arnold, A. M., Mooser, V., Newman, A. B., Widen, E., Parker, A. N., Tsui, K., Plump, A. S., Pop, V. J. M., Psaty, B. M., Rotter, J. I., Scuteri, A., Singleton, A., Wolffenbuttel, B. H. R., Sun, Y. V., Thorand, B., Van Nierop, P., Waeber, G., Wallaschofski, H., Wichmann, H. E., Wijnands-Van Gent, C. J. M., Zygmunt, M., Oostra, B. A. & Schlessinger, D., 1 Mar 2012, In: Nature Genetics. 44, 3, p. 260-268 9 p.

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  • Association of medication with the human plasma N-glycome

    Saldova, R., Huffman, J. E., Adamczyk, B., Mužinić, A., Kattla, J. J., Pučić, M., Novokmet, M., Abrahams, J. L., Hayward, C., Rudan, I., Wild, S. H., Wright, A. F., Polašek, O., Lauc, G., Campbell, H., Wilson, J. F. & Rudd, P. M., 18 Jan 2012, In: Journal Of Proteome Research. 11, 3, p. 1821-31 11 p.

    Research output: Contribution to journalArticlepeer-review

  • A genome-wide association search for type 2 diabetes genes in African Americans

    DIAGRAM Consortium, Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A. & 31 others, Rotimi, C. N., Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Navarro, P., Rudan, I., Campbell, H., Wilson, J. F., Hayward, C., Vitart, V., Wild, S. H. & Wright, A. F., 2012, In: PLoS ONE. 7, 1, p. 1-14 14 p., e29202.

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  • Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

    Murabito, J. M., White, C. C., Kavousi, M., Sun, Y. V., Feitosa, M. F., Nambi, V., Lamina, C., Schillert, A., Coassin, S., Bis, J. C., Broer, L., Crawford, D. C., Franceschini, N., Frikke-Schmidt, R., Haun, M., Holewijn, S., Huffman, J. E., Hwang, S-J., Kiechl, S., Kollerits, B. & 109 others, Montasser, M. E., Nolte, I. M., Rudock, M. E., Senft, A., Teumer, A., van der Harst, P., Vitart, V., Waite, L. L., Wood, A. R., Wassel, C. L., Absher, D. M., Allison, M. A., Amin, N., Arnold, A., Asselbergs, F. W., Aulchenko, Y., Bandinelli, S., Barbalic, M., Boban, M., Brown-Gentry, K., Couper, D. J., Criqui, M. H., Dehghan, A., den Heijer, M., Dieplinger, B., Ding, J., Dörr, M., Espinola-Klein, C., Felix, S. B., Ferrucci, L., Folsom, A. R., Fraedrich, G., Gibson, Q., Goodloe, R., Gunjaca, G., Haltmayer, M., Heiss, G., Hofman, A., Kieback, A., Kiemeney, L. A., Kolcic, I., Kullo, I. J., Kritchevsky, S. B., Lackner, K. J., Li, X., Lieb, W., Lohman, K., Meisinger, C., Melzer, D., Mohler, E. R., Mudnic, I., Mueller, T., Navis, G., Oberhollenzer, F., Olin, J. W., O'Connell, J., O'Donnell, C. J., Palmas, W., Penninx, B. W., Petersmann, A., Polasek, O., Psaty, B. M., Rantner, B., Rice, K., Rivadeneira, F., Rotter, J. I., Seldenrijk, A., Stadler, M., Summerer, M., Tanaka, T., Tybjaerg-Hansen, A., Uitterlinden, A. G., van Gilst, W. H., Vermeulen, S. H., Wild, S. H., Wild, P. S., Willeit, J., Zeller, T., Zemunik, T., Zgaga, L., Assimes, T. L., Blankenberg, S., Boerwinkle, E., Campbell, H., Cooke, J. P., de Graaf, J., Herrington, D., Kardia, S. L. R., Mitchell, B. D., Murray, A., Münzel, T., Newman, A. B., Oostra, B. A., Rudan, I., Shuldiner, A. R., Snieder, H., van Duijn, C. M., Völker, U., Wright, A. F., Wichmann, H-E., Wilson, J. F., Witteman, J. C. M., Liu, Y., Hayward, C., Borecki, I. B., Ziegler, A., North, K. E., Cupples, L. A. & Kronenberg, F., 2012, In: Circulation: Cardiovascular Genetics. 5, 1, p. 100-12 13 p.

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  • Discovery and fine mapping of serum protein loci through transethnic meta-analysis

    LifeLines Cohort Study, Franceschini, N., van Rooij, F. J. A., Prins, B. P., Feitosa, M. F., Karakas, M., Eckfeldt, J. H., Folsom, A. R., Kopp, J., Vaez, A., Andrews, J. S., Baumert, J., Boraska, V., Broer, L., Hayward, C., Ngwa, J. S., Okada, Y., Polasek, O., Westra, H-J., Wang, Y. A. & 31 others, Del Greco M, F., Glazer, N. L., Kapur, K., Kema, I. P., Lopez, L. M., Schillert, A., Smith, A. V., Winkler, C. A., Zgaga, L., Bandinelli, S., Bergmann, S., Boban, M., Bochud, M., Chen, Y. D., Davies, G., Dehghan, A., Ding, J., Doering, A., Durda, J. P., Ferrucci, L., Franco, O. H., Franke, L., Gunjaca, G., Hofman, A., Starr, J. M., Vitart, V., Campbell, H., Deary, I. J., Rudan, I., Wilson, J. F. & Wright, A. F., 2012, In: American Journal of Human Genetics. 91, 4, p. 744-53 10 p.

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  • Evidence of Inbreeding Depression on Human Height

    on behalf of the ROHgen Consortium, McQuillan, R., Eklund, N., Pirastu, N., Kuningas, M., McEvoy, B. P., Esko, T., Corre, T., Davies, G., Kaakinen, M., Lyytikäinen, L-P., Kristiansson, K., Havulinna, A. S., Gögele, M., Vitart, V., Tenesa, A., Aulchenko, Y., Hayward, C., Johansson, A., Boban, M. & 31 others, Ulivi, S., Robino, A., Boraska, V., Igl, W., Wild, S. H., Zgaga, L., Amin, N., Theodoratou, E., Polašek, O., Girotto, G., Lopez, L. M., Sala, C., Lahti, J., Laatikainen, T., Prokopenko, I., Kals, M., Viikari, J., Yang, J., Pouta, A., Estrada, K., Starr, J. M., Farrington, S. M., Campbell, H., Porteous, D., Hastie, N. D., Wright, A. F., Dunlop, M., Rudan, I., Deary, I. J., Visscher, P. M. & Wilson, J. F., 2012, In: PLoS Genetics. 8, 7, e1002655.

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