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  • 2017

    Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

    Xue, Y., Mezzavilla, M., Haber, M., McCarthy, S., Chen, Y., Narasimhan, V., Gilly, A., Ayub, Q., Colonna, V., Southam, L., Finan, C., Massaia, A., Chheda, H., Palta, P., Ritchie, G., Asimit, J., Dedoussis, G., Gasparini, P., Palotie, A., Ripatti, S., & 6 othersSoranzo, N., Daniela, T., Wilson, J., Durbin, R., Tyler-Smith, C. & Zeggini, E., 23 Jun 2017, (E-pub ahead of print) In: Nature Communications.

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  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., Karlsson, R., & 196 othersKolcic, I., Loh, P., Lunetta, K. L., Mangino, M., Marco, B., Mcmahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Bandinelli, S., Beckmann, M. W., Benitez, J., Bergmann, S., Bochud, M., Boerwinkle, E., Bojesen, S. E., Bolla, M. K., Brand, J. S., Brauch, H., Brenner, H., Broer, L., Brüning, T., Buring, J. E., Campbell, H., Catamo, E., Chanock, S., Chenevix-trench, G., Corre, T., Couch, F. J., Cousminer, D. L., Cox, A., Crisponi, L., Czene, K., Davey Smith, G., De Geus, E. J. C. N., De Mutsert, R., De Vivo, I., Dennis, J., Devilee, P., Dos-santos-silva, I., Dunning, A. M., Eriksson, J. G., Fasching, P. A., Fernández-rhodes, L., Ferrucci, L., Flesch-janys, D., Franke, L., Gabrielson, M., Gandin, I., Giles, G. G., Grallert, H., Gudbjartsson, D. F., Guénel, P., Hall, P., Hallberg, E., Hamann, U., Harris, T. B., Hartman, C. A., Heiss, G., Hooning, M. J., Hopper, J. L., Hu, F., Hunter, D. J., Ikram, M. A., Im, H. K., Järvelin, M., Joshi, P. K., Karasik, D., Kellis, M., Kutalik, Z., Lachance, G., Lambrechts, D., Langenberg, C., Launer, L. J., Laven, J. S. E., Lenarduzzi, S., Li, J., Lind, P. A., Lindstrom, S., Liu, Y., Luan, J., Mägi, R., Mannermaa, A., Mbarek, H., Mccarthy, M. I., Meisinger, C., Meitinger, T., Menni, C., Metspalu, A., Michailidou, K., Milani, L., Milne, R. L., Montgomery, G. W., Mulligan, A. M., Nalls, M. A., Navarro, P., Nevanlinna, H., Nyholt, D. R., Oldehinkel, A. J., O'mara, T. A., Padmanabhan, S., Palotie, A., Pedersen, N., Peters, A., Peto, J., Pharoah, P. D. P., Pouta, A., Radice, P., Rahman, I., Ring, S. M., Robino, A., Rosendaal, F. R., Rudan, I., Rueedi, R., Ruggiero, D., Sala, C. F., Schmidt, M. K., Scott, R. A., Shah, M., Sorice, R., Southey, M. C., Sovio, U., Stampfer, M., Steri, M., Strauch, K., Tanaka, T., Tikkanen, E., Timpson, N. J., Traglia, M., Truong, T., Tyrer, J. P., Uitterlinden, A. G., Edwards, D. R. V., Vitart, V., Völker, U., Vollenweider, P., Wang, Q., Widen, E., Van Dijk, K. W., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Zhao, J. H., Zoledziewska, M., Zygmunt, M., Alizadeh, B. Z., Boomsma, D. I., Ciullo, M., Cucca, F., Esko, T., Franceschini, N., Gieger, C., Gudnason, V., Hayward, C., Kraft, P., Lawlor, D. A., Magnusson, P. K. E., Martin, N. G., Mook-kanamori, D. O., Nohr, E. A., Polasek, O., Porteous, D., Price, A. L., Ridker, P. M., Snieder, H., Spector, T. D., Stöckl, D., Toniolo, D., Ulivi, S., Visser, J. A., Völzke, H., Wareham, N. J., Wilson, J. F., Spurdle, A. B., Thorsteindottir, U., Pollard, K. S., Easton, D. F., Tung, J. Y., Chang-claude, J., Hinds, D., Murray, A., Murabito, J. M., Stefansson, K., Ong, K. K. & Perry, J. R. B., Jun 2017, In: Nature Genetics. 49, p. 834-841 7 p.

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  • Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-costa, N. L., Den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., & 262 othersHayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L., Huppertz, C., Willemsen, G., Peyrot, W. J., Wu, Y., Kristiansson, K., Demirkan, A., Fornage, M., Hassinen, M., Bielak, L. F., Cadby, G., Tanaka, T., Mägi, R., Van Der Most, P. J., Jackson, A. U., Bragg-gresham, J. L., Vitart, V., Marten, J., Navarro, P., Bellis, C., Pasko, D., Johansson, Å., Snitker, S., Cheng, Y., Eriksson, J., Lim, U., Aadahl, M., Adair, L. S., Amin, N., Balkau, B., Auvinen, J., Beilby, J., Bergman, R. N., Bergmann, S., Bertoni, A. G., Blangero, J., Bonnefond, A., Bonnycastle, L. L., Borja, J. B., Brage, S., Busonero, F., Buyske, S., Campbell, H., Chines, P. S., Collins, F. S., Corre, T., Smith, G. D., Delgado, G. E., Dueker, N., Dörr, M., Ebeling, T., Eiriksdottir, G., Esko, T., Faul, J. D., Fu, M., Færch, K., Gieger, C., Gläser, S., Gong, J., Gordon-larsen, P., Grallert, H., Grammer, T. B., Grarup, N., Van Grootheest, G., Harald, K., Hastie, N. D., Havulinna, A. S., Hernandez, D., Hindorff, L., Hocking, L. J., Holmens, O. L., Holzapfel, C., Hottenga, J. J., Huang, J., Huang, T., Hui, J., Huth, C., Hutri-kähönen, N., James, A. L., Jansson, J., Jhun, M. A., Juonala, M., Kinnunen, L., Koistinen, H. A., Kolcic, I., Komulainen, P., Kuusisto, J., Kvaløy, K., Kähönen, M., Lakka, T. A., Launer, L. J., Lehne, B., Lindgren, C. M., Lorentzon, M., Luben, R., Marre, M., Milaneschi, Y., Monda, K. L., Montgomery, G. W., De Moor, M. H. M., Mulas, A., Müller-nurasyid, M., Musk, A. W., Männikkö, R., Männistö, S., Narisu, N., Nauck, M., Nettleton, J. A., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Paternoster, L., Perez, J., Perola, M., Peters, A., Peters, U., Peyser, P. A., Prokopenko, I., Puolijoki, H., Raitakari, O. T., Rankinen, T., Rasmussen-torvik, L. J., Rawal, R., Ridker, P. M., Rose, L. M., Rudan, I., Sarti, C., Sarzynski, M. A., Savonen, K., Scott, W. R., Sanna, S., Shuldiner, A. R., Sidney, S., Silbernagel, G., Smith, B. H., Smith, J. A., Snieder, H., Stančáková, A., Sternfeld, B., Swift, A. J., Tammelin, T., Tan, S., Thorand, B., Thuillier, D., Vandenput, L., Vestergaard, H., Van Vliet-ostaptchouk, J. V., Vohl, M., Völker, U., Waeber, G., Walker, M., Wild, S., Wong, A., Wright, A. F., Zillikens, M. C., Zubair, N., Haiman, C. A., Lemarchand, L., Gyllensten, U., Ohlsson, C., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pérusse, L., Wilson, J. F., Hayward, C., Polasek, O., Cucca, F., Hveem, K., Hartman, C. A., Tönjes, A., Bandinelli, S., Palmer, L. J., Kardia, S. L. R., Rauramaa, R., Sørensen, T. I. A., Tuomilehto, J., Salomaa, V., Penninx, B. W. J. H., De Geus, E. J. C., Boomsma, D. I., Lehtimäki, T., Mangino, M., Laakso, M., Bouchard, C., Martin, N. G., Kuh, D., Liu, Y., Linneberg, A., März, W., Strauch, K., Kivimäki, M., Harris, T. B., Gudnason, V., Völzke, H., Qi, L., Järvelin, M., Chambers, J. C., Kooner, J. S., Froguel, P., Kooperberg, C., Vollenweider, P., Hallmans, G., Hansen, T., Pedersen, O., Metspalu, A., Wareham, N. J., Langenberg, C., Weir, D. R., Porteous, D. J., Boerwinkle, E., Chasman, D. I., Abecasis, G. R., Barroso, I., Mccarthy, M. I., Frayling, T. M., O’connell, J. R., Van Duijn, C. M., Boehnke, M., Heid, I. M., Mohlke, K. L., Strachan, D. P., Fox, C. S., Liu, C., Hirschhorn, J. N., Klein, R. J., Johnson, A. D., Borecki, I. B., Franks, P. W., North, K. E., Cupples, L. A., Loos, R. J. F., Kilpeläinen, T. O. & Edwards, T. L. (ed.), 27 Apr 2017, In: PLoS Genetics. 13, 4, p. e1006528 26 p.

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  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A., & 297 othersRenström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Der Most, P. J., Van Vliet-ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., De Borst, G. J., De Craen, A. J. M., De Geus, E. J. C., Dedoussis, G., Delgado, G. E., Den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-kähönen, N., Ingelsson, E., James, A. L., Jansson, J., Jarvelin, M., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-vidal, P., Martin, N. G., Mckenzie, C. A., Mcknight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., Mccarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., Van Der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., Van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p.

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  • A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals

    Wilson, J., 23 Mar 2017, In: BMC Evolutionary Biology.

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  • Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

    Nagy, R., Boutin, T. S., Marten, J., Huffman, J. E., Kerr, S. M., Campbell, A., Evenden, L., Gibson, J., Amador, C., Howard, D. M., Navarro, P., Morris, A., Deary, I. J., Hocking, L. J., Padmanabhan, S., Smith, B. H., Joshi, P., Wilson, J. F., Hastie, N. D., Wright, A. F., & 5 othersMcIntosh, A. M., Porteous, D. J., Haley, C. S., Vitart, V. & Hayward, C., 7 Mar 2017, In: Genome Medicine. 9, 14 p., 23.

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  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Int Consortium Blood Pressure ICBP, CHD Exome Consortium, ExomeBP Consortium, T2D-GENES Consortium, GoT2D Genes Consortium, CHARGE BP Exome Consortium, iGEN-BP Consortium, UK Biobank CardioMetab Consortium, BIOS Consortium, Lifelines Cohort Study, Understanding Soc Sci Grp, Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., & 41 othersCook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J., Snieder, H., Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Magi, R., Hayward, C., Joshi, P. K., Lopez, L. M., Marten, J., Harris, S. E., Campbell, A., Campbell, H., Davies, G., Gow, A. J., Liewald, D. C. M., Morris, A. D., Pattie, A., Rudan, I., Wright, A. F., Starr, J. M., Hayward, C., Vitart, V., Deary, I. J. & Wilson, J. F., Mar 2017, In: Nature Genetics. 49, 3, p. 403-415 13 p.

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  • Estrogens regulate glycosylation of immunoglobulin G in women and men

    Ercan, A., Kohrt, W., Cui, J., Deane, K., Pezer, M., Yu, M., Hausmann, J., Campbell, H., Kaiser, U., Rudd, P. M., Lauc, G., Wilson, J., Finkelstein, J. & Nigrovic, P., 23 Feb 2017, In: JCI Insight.

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  • Genetic variation within the Y chromosome is not associated with histological characteristics of the atherosclerotic carotid artery or aneurysmal wall

    Haitjema, S., Van Setten, J., Eales, J., Van Der Laan, S. W., Gandin, I., De Vries, J. P. M., De Borst, G. J., Pasterkamp, G., Asselbergs, F. W., Charchar, F. J., Wilson, J. F., De Jager, S. C. A., Tomaszewski, M. & Den Ruijter, H. M., 20 Feb 2017, (E-pub ahead of print) In: Atherosclerosis.

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  • Genomic insights into the population structure and history of the Irish Travellers.

    Gilbert, E., Carmi, S., Ennis, S., Wilson, J. & Cavalleri, G. L., 9 Feb 2017, In: Scientific Reports.

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  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Understanding Society Scientific Group, Wain, L. V., Shrine, N., Artigas, M. S., Erzurumluoglu, A. M., Noyvert, B., Bossini-Castillo, L., Obeidat, M., Henry, A. P., Portelli, M. A., Hall, R. J., Billington, C. K., Rimington, T. L., Fenech, A. G., John, C., Blake, T., Jackson, V. E., Allen, R. J., Prins, B. P., Campbell, A., & 31 othersPorteous, D. J., Jarvelin, M-R., Wielscher, M., James, A. L., Hui, J., Wareham, N. J., Zhao, J. H., Wilson, J. F., Joshi, P. K., Stubbe, B., Rawal, R., Schulz, H., Imboden, M., Probst-Hensch, N. M., Karrasch, S., Gieger, C., Deary, I. J., Harris, S. E., Marten, J., Rudan, I., Enroth, S., Gyllensten, U., Kerr, S. M., Polasek, O., Kähönen, M., Surakka, I., Vitart, V., Hayward, C., Lehtimäki, T., Raitakari, O. T. & Morris, A. P., 6 Feb 2017, In: Nature Genetics. 49, 3, p. 416-425 9 p.

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  • New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

    Springelkamp, H., Iglesias, A. I., Mishra, A., Höhn, R., Wojciechowski, R., Khawaja, A. P., Nag, A., Wang, Y. X., Wang, J. J., Cuellar-partida, G., Gibson, J., Cooke Bailey, J. N., Vithana, E. N., Gharahkhani, P., Boutin, T., Ramdas, W. D., Zeller, T., Luben, R. N., Yonova-doing, E., Viswanathan, A. C., & 64 othersYazar, S., Cree, A. J., Haines, J. L., Koh, J. Y., Souzeau, E., Wilson, J. F., Amin, N., Müller, C., Venturini, C., Kearns, L. S., Hee Kang, J., Consortium, N., Tham, Y. C., Zhou, T., Van Leeuwen, E. M., Nickels, S., Sanfilippo, P., Liao, J., Linde, H. V. D., Zhao, W., Van Koolwijk, L. M. E., Zheng, L., Rivadeneira, F., Baskaran, M., Van Der Lee, S. J., Perera, S., De Jong, P. T. V. M., Oostra, B. A., Uitterlinden, A. G., Fan, Q., Hofman, A., Shyong Tai, E., Vingerling, J. R., Sim, X., Wolfs, R. C. W., Teo, Y. Y., Lemij, H. G., Khor, C. C., Willemsen, R., Lackner, K. J., Aung, T., Jansonius, N. M., Montgomery, G., Wild, P. S., Young, T. L., Burdon, K. P., Hysi, P. G., Pasquale, L. R., Wong, T. Y., Klaver, C. C. W., Hewitt, A. W., Jonas, J. B., Mitchell, P., Lotery, A. J., Foster, P. J., Vitart, V., Pfeiffer, N., Craig, J. E., Mackey, D. A., Hammond, C. J., Wiggs, J. L., Cheng, C., Van Duijn, C. M. & Macgregor, S., 15 Jan 2017, In: Human Molecular Genetics. p. ddw399

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  • Evidence for large-scale gene-by-smoking interaction effects on pulmonary function

    Aschard, H., Tobin, M. D., Hancock, D. B., Skurnik, D., Sood, A., James, A., Smith, A. V., Manichaikul, A., Campbell, A., Prins, B. P., Hayward, C., Loth, D. W., Porteous, D., Strachan, D. P., Zeggini, E., O'Connor, G. T., Brusselle, G. G., Boezen, H. M., Schulz, H., Deary, I. J., & 30 othersHall, I. P., Rudan, I., Kaprio, J., Wilson, J., Wilk, J. B., Huffman, J., Zhao, J. H., de Jong, K., Lyytikäinen, L-P., Wain, L. V., Jarvelin, M-R., Kahonen, M., Fornage, M., Polasek, O., Cassano, P. A., Barr, R. G., Rawal, R., Harris, S., Gharib, S. A., Enroth, S., Heckbert, S. R., Lehtimaki, T., Gyllensten, U., Jackson, V. E., Gudnason, V., Tang, W., Dupuis, J., Artigas, M. S., Joshi, A. D. & Kraft, P., 12 Jan 2017, (E-pub ahead of print) In: International Journal of Epidemiology.

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  • 2016

    KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

    Schumann, G., Liu, C., O'Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., Segura Lepe, M., Akira, S., Barbieri, C., Baumeister, S., Cauchi, S., Clarke, T-K., Enroth, S., Fischer, K., Hällfors, J., Harris, S. E., & 107 othersHieber, S., Hofer, E., Hottenga, J-J., Johansson, Å., Joshi, P. K., Kaartinen, N., Laitinen, J., Lemaitre, R., Loukola, A., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Mbarek, H., Milaneschi, Y., Moayyeri, A., Mukamal, K., Nelson, C., Nettleton, J., Partinen, E., Rawal, R., Robino, A., Rose, L., Sala, C., Satoh, T., Schmidt, R., Schraut, K., Scott, R., Smith, A. V., Starr, J. M., Teumer, A., Trompet, S., Uitterlinden, A. G., Venturini, C., Vergnaud, A-C., Verweij, N., Vitart, V., Vuckovic, D., Wedenoja, J., Yengo, L., Yu, B., Zhang, W., Zhao, J. H., Boomsma, D. I., Chambers, J., Chasman, D. I., Daniela, T., de Geus, E., Deary, I., Eriksson, J. G., Esko, T., Eulenburg, V., Franco, O. H., Froguel, P., Gieger, C., Grabe, H. J., Gudnason, V., Gyllensten, U., Harris, T. B., Hartikainen, A-L., Heath, A. C., Hocking, L., Hofman, A., Huth, C., Jarvelin, M-R., Jukema, J. W., Kaprio, J., Kooner, J. S., Kutalik, Z., Lahti, J., Langenberg, C., Lehtimäki, T., Liu, Y., Madden, P. A. F., Martin, N., Morrison, A., Penninx, B., Pirastu, N., Psaty, B., Raitakari, O., Ridker, P., Rose, R., Rotter, J. I., Samani, N. J., Schmidt, H., Spector, T. D., Stott, D., Strachan, D., Tzoulaki, I., van der Harst, P., van Duijn, C. M., Marques-Vidal, P., Vollenweider, P., Wareham, N. J., Whitfield, J. B., Wilson, J., Wolffenbuttel, B., Bakalkin, G., Evangelou, E., Liu, Y., Rice, K. M., Desrivières, S., Kliewer, S. A., Mangelsdorf, D. J., Müller, C. P., Levy, D. & Elliott, P., 13 Dec 2016, In: Proceedings of the National Academy of Sciences (PNAS).

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., BIOS Consortium, Ahluwalia, T. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., & 235 othersAyers, K., Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Gieger, C., Gunderson, E. P., Guo, X., Hayward, C., He, C., Hofer, E., Huang, H., Joshi, P. K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R., Lind, P. A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P. F., McMahon, G., Meddens, S. F. W., Mihailov, E., Miller, M., Missmer, S. A., Monnereau, C., van der Most, P. J., Myhre, R., Nalls, M. A., Nutile, T., Kalafati, I. P., Porcu, E., Prokopenko, I., Rajan, K. B., Rich-Edwards, J., Rietveld, C. A., Robino, A., Rose, L. M., Rueedi, R., Ryan, K. A., Saba, Y., Schmidt, D., Smith, J. A., Stolk, L., Streeten, E., Tönjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J. H., Zhao, W., Zhernakova, D. V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bønnelykke, K., Boomsma, D. I., Buring, J. E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S. R., Cucca, F., Toniolo, D., Davey-Smith, G., Deary, I. J., Dedoussis, G., Deloukas, P., van Duijn, C. M., de Geus, E. J. C., Eriksson, J. G., Evans, D. A., Faul, J. D., Sala, C. F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H-J., Greiser, K. H., Groenen, P. J. F., de Haan, H. G., Haerting, J., Harris, T. B., Heath, A. C., Heikkilä, K., Hofman, A., Homuth, G., Holliday, E. G., Hopper, J., Hyppönen, E., Jacobsson, B., Jaddoe, V. W. V., Johannesson, M., Jugessur, A., Kähönen, M., Kajantie, E., Kardia, S. L. R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., La Bianca, M., Lachance, G., Iacono, W. G., Lai, S., Lehtimäki, T., Liewald, D. C., LifeLines Cohort Study, Lindgren, C. M., Liu, Y., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P. K. E., Martin, N. G., McGue, M., McQuillan, R., Medland, S. E., Meisinger, C., Mellström, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G. W., Mook-Kanamori, D., de Mutsert, R., Nohr, E. A., Ohlsson, C., Olsen, J., Ong, K. K., Paternoster, L., Pattie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L. J., Räikkönen, K., Raitakari, O., Ridker, P. M., Ring, S. M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J., Sorice, R., Spector, T. D., Starr, J. M., Stöckl, D., Strauch, K., Stumvoll, M., Swertz, M. A., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tung, J. Y., Uitterlinden, A. G., Vaccargiu, S., Viikari, J., Vitart, V., Völzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G. G., Wang, J. J., J Wareham, N., Weir, D. R., Willemsen, G., Willeit, J., Wright, A. F., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J., Cesarini, D., Koellinger, P. D., den Hoed, M., Snieder, H. & Mills, M. C., Dec 2016, In: Nature Genetics. 48, 12, p. 1462–1472 11 p.

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  • Genetic variants linked to education predict longevity

    Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J., Gale, C. R., & 13 othersDeary, I. J., Social Science Genetic Association Consortium, Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J. & Gale, C. V., 22 Nov 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 47, p. 13366-13371 6 p.

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  • Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    CHARGE Consortium, Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., & 31 othersSmith, A. V., Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Wardlaw, J. M., Deary, I. J. & Wilson, J. G., 21 Nov 2016, In: Circulation: Cardiovascular Genetics.

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  • A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Ried, J. S., Jeff M., J., Chu, A. Y., Bragg-gresham, J. L., Van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K., & 256 othersKutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Stančáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., Van Der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D’avila, F., De Geus, E. J. . C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Marie Justesen, J., Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, A., Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., Mcardle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., Van Der Most, P. J., Van Vliet-ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-armstrong, L. M., Hua Zhao, J., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, T., Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, O., Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, P. E. H., Shudiner, A. R., Smit, J. H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., Van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., Mccarthy, M. I., North, K. E., O'connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-nurasyid, M. & Loos, R. J. F., Nov 2016, In: Nature Communications. 7, p. 13357

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  • Genome-wide associations for birth weight and correlations with adult disease

    Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-tajes, J., Feenstra, B., Van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-gao, R., Ahluwalia, T. S., Kreiner, E., Rueedi, R., Lyytikäinen, L., Cousminer, D. L., Wu, Y., Thiering, E., & 32 othersWang, C. A., Have, C. T., Hottenga, J-J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Bennett, A. J., Rahmioglu, N., Nyholt, D. R., Ma, R. C. W., Tam, C. H. T., Tam, W. H., CHARGE Consortium Hematology Working Group, Ganesh, S. K., Van Rooij, F. J. A., Reynolds, R. M., Early Growth Genetics (EGG) consortium, Campbell, H., Wilson, J. F. & Walker, B. R., 13 Oct 2016, In: Nature. 538, 7624, p. 248-252 5 p.

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  • A case-control study in an Orcadian population investigating the relationship between human plasma N-glycans and metabolic syndrome.

    McLachlan, F., Timofeeva, M., Bermingham, M., Wild, S., Rudan, I., Lauc, G., Wang, W., Campbell, H., Wilson, J. & Theodoratou, E., 8 Oct 2016, (E-pub ahead of print) In: Journal of glycomics & Lipidomics.

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  • 52 Genetic Loci Influencing Myocardial Mass

    van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polasek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M., & 140 othersSmith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S-J., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, A., Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, J. V., Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, T. H., Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S-T., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H-J., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sept 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.

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  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    CHARGE-EchoGen Consortium, CHARGE-HF Consortium & Wellcome Trust Case Control Consortium, 12 Sept 2016, In: Nature Genetics. 48, 10, p. 1171-1184

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  • Genomic insights into the origin of farming in the ancient Near East

    Lazaridis, I., Nadel, D., Rollefson, G., Merrett, D. C., Rohland, N., Mallick, S., Fernandes, D., Novak, M., Gamarra, B., Sirak, K., Connell, S., Stewardson, K., Harney, E., Fu, Q., Gonzalez-Fortes, G., Jones, E. R., Roodenberg, S. A., Lengyel, G., Bocquentin, F., Gasparian, B., & 33 othersMonge, J. M., Gregg, M., Eshed, V., Mizrahi, A-S., Meiklejohn, C., Gerritsen, F., Bejenaru, L., Blüher, M., Campbell, A., Cavalleri, G., Comas, D., Froguel, P., Gilbert, E., Kerr, S. M., Kovacs, P., Krause, J., McGettigan, D., Merrigan, M., Merriwether, D. A., O'Reilly, S., Richards, M. B., Semino, O., Shamoon-Pour, M., Stefanescu, G., Stumvoll, M., Tönjes, A., Torroni, A., Wilson, J. F., Yengo, L., Hovhannisyan, N. A., Patterson, N., Pinhasi, R. & Reich, D., 25 Aug 2016, In: Nature. 536, 7617, p. 419–424 6 p.

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  • A reference panel of 64,976 haplotypes for genotype imputation

    Mccarthy, S., Das, S., Kretzschmar, W., Delaneau, O., Wood, A. R., Teumer, A., Kang, H. M., Fuchsberger, C., Danecek, P., Sharp, K., Luo, Y., Sidore, C., Kwong, A., Timpson, N., Koskinen, S., Vrieze, S., Scott, L. J., Zhang, H., Mahajan, A., Veldink, J., & 91 othersPeters, U., Pato, C., Van Duijn, C. M., Gillies, C. E., Gandin, I., Mezzavilla, M., Gilly, A., Cocca, M., Traglia, M., Angius, A., Barrett, J. C., Boomsma, D., Branham, K., Breen, G., Brummett, C. M., Busonero, F., Campbell, H., Chan, A., Chen, S., Chew, E., Collins, F. S., Corbin, L. J., Smith, G. D., Dedoussis, G., Dorr, M., Farmaki, A., Ferrucci, L., Forer, L., Fraser, R. M., Gabriel, S., Levy, S., Groop, L., Harrison, T., Hattersley, A., Holmen, O. L., Hveem, K., Kretzler, M., Lee, J. C., Mcgue, M., Meitinger, T., Melzer, D., Min, J. L., Mohlke, K. L., Vincent, J. B., Nauck, M., Nickerson, D., Palotie, A., Pato, M., Pirastu, N., Mcinnis, M., Richards, J. B., Sala, C., Salomaa, V., Schlessinger, D., Schoenherr, S., Slagboom, P. E., Small, K., Spector, T., Stambolian, D., Tuke, M., Tuomilehto, J., Van Den Berg, L. H., Van Rheenen, W., Volker, U., Wijmenga, C., Toniolo, D., Zeggini, E., Gasparini, P., Sampson, M. G., Wilson, J. F., Frayling, T., De Bakker, P. I. W., Swertz, M. A., Mccarroll, S., Kooperberg, C., Dekker, A., Altshuler, D., Willer, C., Iacono, W., Ripatti, S., Soranzo, N., Walter, K., Swaroop, A., Cucca, F., Anderson, C. A., Myers, R. M., Boehnke, M., Mccarthy, M. I., Durbin, R., Abecasis, G. & Marchini, J., 22 Aug 2016, (E-pub ahead of print) In: Nature Genetics. 48, 10, p. 1279-1283

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  • Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

    Jones, S. E., Tyrrell, J., Wood, A. R., Beaumont, R. N., Ruth, K. S., Tuke, M. A., Yaghootkar, H., Hu, Y., Teder-laving, M., Hayward, C., Roenneberg, T., Wilson, J. F., Del Greco, F., Hicks, A. A., Shin, C., Yun, C., Lee, S. K., Metspalu, A., Byrne, E. M., Gehrman, P. R., & 8 othersTiemeier, H., Allebrandt, K. V., Freathy, R. M., Murray, A., Hinds, D. A., Frayling, T. M., Weedon, M. N. & Shi, J. (ed.), 5 Aug 2016, In: PLoS Genetics. 12, 8, e1006125.

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  • Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

    Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D., & 93 othersRaffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M-P., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, T., Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, A., Liu, Y., Lu, Y., Lyytikäinen, L-P., Mägi, R., Mathias, R. A., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, O., Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A-C., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, N., Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

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  • Large-scale exome-wide association analysis identifies loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

    Tajuddin, S. M., Schick, U. M., Eicher, J. D., Chami, N., Giri, A., Brody, J. A., Hill, W. D., Kacprowski, T., Li, J., Lyytikäinen, L-P., Manichaikul, A., Mihailov, E., O'Donoghue, M. L., Pankratz, N., Pazoki, R., Polfus, L. M., Smith, A. V., Schurmann, C., Vacchi-Suzzi, C., Waterworth, D. M., & 77 othersEvangelou, E., Yanek, L. R., Burt, A., Chen, M-H., van Rooij, F. J. A., Floyd, J. S., Greinacher, A., Harris, T. B., Highland, H. M., Lange, L. A., Liu, Y., Mägi, R., Nalls, M. A., Mathias, R. A., Nickerson, D. A., Nikus, K., Starr, J. M., Tardif, J-C., Tzoulaki, I., Velez Edwards, D. R., Wallentin, L., Bartz, T. M., Becker, L. C., Denny, J. C., Raffield, L. M., Rioux, J. D., Friedrich, N., Fornage, M., Gao, H., Hirschhorn, J. N., Liewald, D. C. M., Rich, S. S., Uitterlinden, A., Bastarache, L., Becker, D. M., Boerwinkle, E., de Denus, S., Bottinger, E. P., Hayward, C., Hofman, A., Homuth, G., Lange, E., Launer, L. J., Lehtimäki, T., Lu, Y., Metspalu, A., O'Donnell, C. J., Quarells, R. C., Richard, M., Torstenson, E. S., Taylor, K. D., Vergnaud, A-C., Zonderman, A. B., Crosslin, D. R., Deary, I. J., Dörr, M., Elliott, P., Evans, M. K., Gudnason, V., Kähönen, M., Psaty, B. M., Rotter, J. I., Slater, A. J., Dehghan, A., White, H. D., Ganesh, S. K., Loos, R. J. F., Esko, T., Faraday, N., Wilson, J. G., Cushman, M., Johnson, A. D., Edwards, T. L., Zakai, N. A., Lettre, G., Reiner, A. P. & Auer, P. L., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 22-39 18 p.

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  • Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence

    Cáceres, A., Esko, T., Pappa, I., Gutiérrez, A., Lopez-espinosa, M., Llop, S., Bustamante, M., Tiemeier, H., Metspalu, A., Joshi, P. K., Wilson, J., Reina-castillón, J., Shin, J., Pausova, Z., Paus, T., Sunyer, J., Pérez-jurado, L. A. & González, J. R., 29 Jun 2016, In: PLoS ONE. 11, 6, p. e0157739

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  • Genome-wide association study identifies 74 loci associated with educational attainment

    LifeLines Cohort Study, 26 May 2016, In: Nature. 533, 7604, p. 539-542 4 p.

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  • Farming, foreign holidays, and vitamin D in Orkney

    Weiss, E., Zgaga, L., Read, S., Wild, S., Dunlop, M., Campbell, H., McQuillan, R. & Wilson, J., 17 May 2016, In: PLoS ONE. e0155633.

    Research output: Contribution to journalArticlepeer-review

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  • Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

    Fan, Q., Guo, X., Tideman, J. W. L., Williams, K. M., Yazar, S., Hosseini, S. M., Howe, L. D., Pourcain, B. S., Evans, D. M., Timpson, N. J., McMahon, G., Hysi, P. G., Krapohl, E., Wang, Y. X., Jonas, J. B., Baird, P. N., Wang, J. J., Cheng, C. Y., Teo, Y. Y., Wong, T. Y., & 112 othersDing, X., Wojciechowski, R., Young, T. L., Pärssinen, O., Oexle, K., Pfeiffer, N., Bailey-Wilson, J. E., Paterson, A. D., Klaver, C. C. W., Plomin, R., Hammond, C. J., He, M., Saw, S. M., Guggenheim, J. A., Meguro, A., Wright, A. F., Hewitt, A. W., Young, A. L., Veluchamy, A. B., Metspalu, A., Döring, A., Khawaja, A. P., Klein, B. E., St Pourcain, B., Fleck, B., Klaver, C. C. W., Hayward, C., Williams, C., Delcourt, C., Pang, C. P., Khor, C. C., Gieger, C., Simpson, C. L., Van Duijn, C. M., Mackey, D. A., Stambolian, D., Chew, E., Tai, E. S., Mihailov, E., Smith, G. D., Biino, G., Campbell, H., Rudan, I., Seppälä, I., Kaprio, J., Wilson, J. F., Craig, J. E., Ried, J. S., Korobelnik, J. F., Fondran, J. R., Liao, J., Zhao, J. H., Xie, J., Kemp, J. P., Lass, J. H., Rahi, J. S., Wedenoja, J., Mäkelä, K. M., Burdon, K. P., Khaw, K. T., Yamashiro, K., Chen, L. J., Xu, L., Farrer, L., Ikram, M. K., Deangelis, M. M., Morrison, M., Schache, M., Pirastu, M., Miyake, M., Yap, M. K. H., Fossarello, M., Kähönen, M., Tedja, M. S., Yoshimura, N., Martin, N. G., Wareham, N. J., Mizuki, N., Raitakari, O., Polasek, O., Tam, P. O., Foster, P. J., Mitchell, P., Chen, P., Cumberland, P., Gharahkhani, P., Höhn, R., Fogarty, R. D., Luben, R. N., Igo, R. P., Klein, R., Janmahasatian, S., Yip, S. P., Feng, S., Vaccargiu, S., Panda-Jonas, S., MacGregor, S., Iyengar, S. K., Rantanen, T., Lehtimäki, T., Meitinger, T., Aung, T., Haller, T., Vitart, V., Nangia, V., Verhoeven, V. J. M., Jhanji, V., Zhao, W., Chen, W., Zhou, X., Lu, Y. & Vatavuk, Z., 13 May 2016, In: Scientific Reports. 6, 25853.

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  • Genetic variants in RBFOX3 are associated with sleep latency

    Amin, N., Allebrandt, K. V., van der Spek, A., Müller-Myhsok, B., Hek, K., Teder-Laving, M., Hayward, C., Esko, T., van Mill, J. G., Mbarek, H., Watson, N. F., Melville, S. A., Del Greco, F. M., Byrne, E. M., Oole, E., Kolcic, I., Chen, T-H., Evans, D. S., Coresh, J., Vogelzangs, N., & 54 othersKarjalainen, J., Willemsen, G., Gharib, S. A., Zgaga, L., Mihailov, E., Stone, K. L., Campbell, H., Brouwer, R. W., Demirkan, A., Isaacs, A., Dogas, Z., Marciante, K. D., Campbell, S., Borovecki, F., Luik, A. I., Li, M., Hottenga, J. J., Huffman, J. E., van den Hout, M. C., Cummings, S. R., Aulchenko, Y. S., Gehrman, P. R., Uitterlinden, A. G., Wichmann, H-E., Müller-Nurasyid, M., Fehrmann, R. S., Montgomery, G. W., Hofman, A., Kao, W. H. L., Oostra, B. A., Wright, A. F., Vink, J. M., Wilson, J. F., Pramstaller, P. P., Hicks, A. A., Polasek, O., Punjabi, N. M., Redline, S., Psaty, B. M., Heath, A. C., Merrow, M., Tranah, G. J., Gottlieb, D. J., Boomsma, D. I., Martin, N. G., Rudan, I., Tiemeier, H., van IJcken, W. F., Penninx, B. W., Metspalu, A., Meitinger, T., Franke, L., Roenneberg, T. & van Duijn, C. M., 4 May 2016, In: European Journal of Human Genetics.

    Research output: Contribution to journalArticlepeer-review

  • Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

    Fan, Q., Verhoeven, V. J. M., Wojciechowski, R., Barathi, V. A., Hysi, P. G., Guggenheim, J. A., Höhn, R., Vitart, V., Khawaja, A. P., Yamashiro, K., Hosseini, S. M., Lehtimäki, T., Lu, Y., Haller, T., Xie, J., Delcourt, C., Pirastu, M., Wedenoja, J., Gharahkhani, P., Venturini, C., & 134 othersMiyake, M., Hewitt, A. W., Guo, X., Mazur, J., Huffman, J. E., Williams, K. M., Polasek, O., Campbell, H., Rudan, I., Vatavuk, Z., Wilson, J. F., Joshi, P. K., Mcmahon, G., St Pourcain, B., Evans, D. M., Simpson, C. L., Schwantes-an, T., Igo, R. P., Mirshahi, A., Cougnard-gregoire, A., Bellenguez, C., Blettner, M., Raitakari, O., Kähönen, M., Seppala, I., Zeller, T., Meitinger, T., Ried, J. S., Gieger, C., Portas, L., Van Leeuwen, E. M., Amin, N., Uitterlinden, A. G., Rivadeneira, F., Hofman, A., Vingerling, J. R., Wang, Y. X., Wang, X., Tai-hui Boh, E., Ikram, M. K., Sabanayagam, C., Gupta, P., Tan, V., Zhou, L., Ho, C. E. H., Lim, W., Beuerman, R. W., Siantar, R., Tai, E., Vithana, E., Mihailov, E., Khor, C., Hayward, C., Luben, R. N., Foster, P. J., Klein, B. E. K., Klein, R., Wong, H., Mitchell, P., Metspalu, A., Aung, T., Young, T. L., He, M., Pärssinen, O., Van Duijn, C. M., Jin Wang, J., Williams, C., Jonas, J. B., Teo, Y., Mackey, D. A., Oexle, K., Yoshimura, N., Paterson, A. D., Pfeiffer, N., Wong, T., Baird, P. N., Stambolian, D., Wilson, J. E. B., Cheng, C., Hammond, C. J., Klaver, C. C. W., Saw, S., Rahi, J. S., Korobelnik, J., Kemp, J. P., Timpson, N. J., Smith, G. D., Craig, J. E., Burdon, K. P., Fogarty, R. D., Iyengar, S. K., Chew, E., Janmahasatian, S., Martin, N. G., Macgregor, S., Xu, L., Schache, M., Nangia, V., Panda-jonas, S., Wright, A. F., Fondran, J. R., Lass, J. H., Feng, S., Zhao, J. H., Khaw, K., Wareham, N. J., Rantanen, T., Kaprio, J., Pang, C. P., Chen, L. J., Tam, P. O., Jhanji, V., Young, A. L., Döring, A., Raffel, L. J., Cotch, M., Li, X., Yip, S. P., Yap, M. K. H., Biino, G., Vaccargiu, S., Fossarello, M., Fleck, B., Yazar, S., Tideman, J. W. L., Tedja, M., Deangelis, M. M., Morrison, M., Farrer, L., Zhou, X., Chen, W., Mizuki, N., Meguro, A. & Mäkelä, K. M., 6 Apr 2016, In: Nature Communications. 7, p. 11008

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  • Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

    LifeLines Cohort Study, van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., Feitosa, M. F., Demissie, S., Joshi, P. K., Duan, Q., Marten, J., van Klinken, J. B., Surakka, I., Nolte, I. M., Zhang, W., Mbarek, H., Li-Gao, R., Trompet, S., Verweij, N., & 31 othersEvangelou, E., Lyytikäinen, L-P., Tayo, B. O., Deelen, J., van der Most, P. J., van der Laan, S. W., Arking, D. E., Morrison, A., Dehghan, A., Franco, O. H., Hofman, A., Rivadeneira, F., Sijbrands, E. J., Uitterlinden, A. G., Mychaleckyj, J. C., Campbell, A., Hocking, L. J., Padmanabhan, S., Brody, J. A., Rice, K. M., White, C. C., Harris, T., Isaacs, A., Campbell, H., Lange, L. A., Rudan, I., Kolcic, I., Navarro, P., Vitart, V., Hayward, C. & Wilson, J. F., 1 Apr 2016, In: Journal of Medical Genetics.

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  • The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study

    Wang, Y., Klarić, L., Yu, X., Thaqi, K., Dong, J., Novokmet, M., Wilson, J., Polasek, O., Liu, Y., Krištić, J., Ge, S., Pučić-Baković, M., Wu, L., Zhou, Y., Ugrina, I., Song, M., Zhang, J., Guo, X., Zeng, Q., Rudan, I., & 4 othersCampbell, H., Aulchenko, Y., Lauc, G. & Wang, W., Apr 2016, In: Medicine. 95, 17, p. e3379

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  • Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

    Joshi, P. K., Fischer, K., Schraut, K. E., Campbell, H., Esko, T. & Wilson, J. F., 31 Mar 2016, In: Nature Communications. 7, 7 p., 11174.

    Research output: Contribution to journalArticlepeer-review

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  • Association of Forced Vital Capacity with the Developmental Gene NCOR2

    Generation Scotland, 2 Feb 2016, In: PLoS ONE. 11, 2, e0147388.

    Research output: Contribution to journalArticlepeer-review

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S., & 239 othersLagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H-J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., de Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B-G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Mateo Leach, I., Lee, C. G., Lee, J-Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikäinen, L-P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Narančić, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., van der Velde, N., van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., Mcknight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., Mckenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I. A., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., van der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M-C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpeläinen, T. O. & Loos, R. J. F., 1 Feb 2016, In: Nature Communications. 7, p. 10495

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  • GWAS for executive function and processing speed suggests involvement of the CADM2 gene

    Generation Scotland, Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., & 31 othersKarjalainen, J., Lahti, J., Llewellyn, D. J., Schmidt, C. O., Mather, K. A., Chouraki, V., Sun, Q., Resnick, S. M., Rose, L. M., Oldmeadow, C., Stewart, M., Smith, B. H., Gudnason, V., Yang, Q., Mirza, S. S., Jukema, J. W., deJager, P. L., Harris, T. B., Liewald, D., Amin, N., Gow, A. J., Pattie, A., Starr, J. M., McLachlan, S., Porteous, D. J., Price, J. F., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F. & Deary, I., Feb 2016, In: Molecular Psychiatry. 21, p. 189-197

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  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    ICBP Consortium, Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M-H., Pers, T. H., Johnson, A. D., Ko, Y-A., Fuchsberger, C., & 31 othersTayo, B., Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., d'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., van der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Hayward, C., Campbell, H., Rudan, I., Wilson, J. F., Martin, N. G., Hastie, N., Polasek, O., Mitchell, P., Wild, S. H. & Vitart, V., 21 Jan 2016, In: Nature Communications. 7, 10023.

    Research output: Contribution to journalArticlepeer-review

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  • Resolving the ancestry of Austronesian-speaking populations

    Soares, P. A., Trejaut, J. A., Rito, T., Cavadas, B., Hill, C., Eng, K. K., Mormina, M., Brandão, A., Fraser, R. M., Wang, T-Y., Loo, J-H., Snell, C., Ko, T-M., Amorim, A., Pala, M., Macaulay, V., Bulbeck, D., Wilson, J. F., Gusmão, L., Pereira, L., & 3 othersOppenheimer, S., Lin, M. & Richards, M. B., 18 Jan 2016, In: Human Genetics.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • 2015

    Integrative pathway genomics of lung function and airflow obstruction

    CHARGE Consortium; SpiroMeta Consortium, Gharib, S. A., Loth, D. W., Soler Artigas, M., Birkland, T. P., Wilk, J. B., Wain, L. V., Brody, J. A., Obeidat, M., Hancock, D. B., Tang, W., Rawal, R., Boezen, H. M., Imboden, M., Huffman, J. E., Lahousse, L., Alves, A. C., Manichaikul, A., Hui, J., Morrison, A. C., & 30 othersRamasamy, A., Smith, A. V., Gudnason, V., Surakka, I., Vitart, V., Evans, D. M., Strachan, D. P., Deary, I. J., Hofman, A., Gläser, S., Wilson, J. F., North, K. E., Zhao, J. H., Heckbert, S. R., Jarvis, D. L., Probst-Hensch, N., Schulz, H., Barr, R. G., Jarvelin, M-R., O'Connor, G. T., Kähönen, M., Cassano, P. A., Hysi, P. G., Dupuis, J., Hayward, C., Psaty, B. M., Hall, I. P., Parks, W. C., Tobin, M. D. & London, S. J., 22 Dec 2015, In: Human Molecular Genetics. 24, 23, p. 6836-48 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    UK BiLEVE, Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., & 31 othersMarten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L-P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C-A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A-L., Henderson, J., Navarro, P., Starr, J. M., Wild, S. H., Wright, A. F., Vitart, V., Rudan, I., Deary, I. J., Wilson, J. F., Morris, A. P. & Hayward, C., 4 Dec 2015, In: Nature Communications. 6, p. 8658

    Research output: Contribution to journalArticlepeer-review

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  • Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

    Generation Scotland, LifeLines Cohort Study & CHARGE Lipids Working Group, 12 Nov 2015, In: npj Aging and Mechanisms of Disease. 1, 1, 15011.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration

    de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R., & 111 othersYanek, L. R., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Willemsen, G., Rumley, A., Fiorillo, E., de Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L. M., Berentzen, T. L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D-A., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., de Maat, M. P. M., de Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K-T., McKnight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., McEvoy, M. G., Becker, D. M., Starr, J. M., Sarin, A-P., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Koenig, W., Psaty, B. M., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P-E., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, T., Deary, I. J., Becker, L. C., Scott, R. J., Mitchell, R., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Jukema, J. W., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 10 Nov 2015, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Day, F. R., Ruth, K. S., Thompson, D. J., Lunetta, K. L., Pervjakova, N., Chasman, D. I., Stolk, L., Finucane, H. K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A. D., Elks, C. E., Franceschini, N., He, C., Altmaier, E., Brody, J. A., Franke, L. L., Huffman, J. E., Keller, M. F., & 32 othersMcArdle, P. F., Nutile, T., Porcu, E., Robino, A., Rose, L. M., Schick, U. M., Smith, J. A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J-J., Mangino, M., Smith, A. V., Boutin, T. S., Campbell, A., Campbell, H., Figueroa, J., Pirastu, N., Pirie, A., Polasek, O., Porteous, D., Rudan, I., Wilson, J. F., Wright, A. F., Hayward, C., PRACTICAL Consortium & Tomlinson, I., Nov 2015, In: Nature Genetics. 47, 11, p. 1294-303 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association studies identify genetic loci for low von Willebrand factor levels

    van Loon, J., Dehghan, A., Weihong, T., Trompet, S., McArdle, W. L., Asselbergs, F. F. W., Chen, M-H., Lopez, L. M., Huffman, J. E., Leebeek, F. W. G., Basu, S., Stott, D. J., Rumley, A., Gansevoort, R. T., Davies, G., Wilson, J. J. F., Witteman, J. C. M., Cao, X., de Craen, A. J. M., Bakker, S. J. L., & 13 othersPsaty, B. M., Starr, J. M., Hofman, A., Wouter Jukema, J., Deary, I. J., Hayward, C., van der Harst, P., Lowe, G. D. O., Folsom, A. R., Strachan, D. P., Smith, N., de Maat, M. P. M. & O'Donnell, C., 21 Oct 2015, (E-pub ahead of print) In: European Journal of Human Genetics. 24, 7, p. 1035-1040

    Research output: Contribution to journalArticlepeer-review

  • The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape

    Busby, G. B. J., Hellenthal, G., Montinaro, F., Tofanelli, S., Bulayeva, K., Rudan, I., Zemunik, T., Hayward, C., Toncheva, D., Karachanak-Yankova, S., Nesheva, D., Anagnostou, P., Cali, F., Brisighelli, F., Romano, V., Lefranc, G., Buresi, C., Ben Chibani, J., Haj-Khelil, A., Denden, S., & 8 othersPloski, R., Krajewski, P., Hervig, T., Moen, T., Herrera, R. J., Wilson, J. F., Myers, S. & Capelli, C., 5 Oct 2015, In: Current biology : CB. 25, 19, p. 2518-26 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

    Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., Billington, C. K., Kheirallah, A. K., Allen, R., Cook, J. P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D. S., Paré, P. D., Ramasamy, A., Mägi, R., Mihailov, E., Reinmaa, E., & 138 othersMelén, E., O'Connell, J., Frangou, E., Delaneau, O., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., Hall, I. P., Farrall, M., Barroso, I., Anderson, C. A., Botía, J., Vandrocova, J., Guelfi, S., D'Sa, K., Ryten, M., Trabzuni, D., Matarin, M., Hardy, J. A., Weale, M. E., Varghese, V., Forabosco, P., Farmer, A., McGuffin, P., Zgaga, L., Wilson, J. F., Wild, S. H., Campbell, H., Rudan, I., Smith, C., Walker, R., Liu, J. Z., Tozzi, F., Muglia, P., Waterworth, D. M., Pillai, S. G., Yuan, X., Mooser, V., Middleton, L., Kooner, J., Chambers, J. C., Berrettini, W., Knouff, C. W., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Khaw, K. T., Grundy, S., Barter, P., Mahley, R., Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H. E., Rawal, R., Wichmann, H. E., Lamina, C., Dahmen, N., Polasek, O., Kolcic, I., Huffman, J., Campbell, S., Vitart, V., Hayward, C., Wright, A. F., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Epstein, S., Reilly, M. P., Li, M., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Rader, D. J., Ellinghaus, D., Lieb, W., Franke, A., Uda, M., Busonero, F., Terracciano, A., Schlessinger, D., Xiao, X., Scheet, P., St Clair, D., Rujescu, D., Abecasis, G. R., Grabe, H. J., Teumer, A., Völzke, H., Petersmann, A., John, U., Wright, B. J., Thompson, J. R., Balmforth, A. J., Hall, A. S., Samani, N. J., Ahmad, T., Mathew, C. G., Parkes, M., Satsangi, J., Caulfield, M., Munroe, P. B., Dominiczak, A., Worthington, J., Thomson, W., Eyre, S., Barton, A. & Francks, C., 1 Oct 2015, In: The Lancet Respiratory Medicine. 3, 10, p. 769-781 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Molecular mechanisms underlying variations in lung function: a systems genetics analysis

    Obeidat, M., Hao, K., Bossé, Y., Nickle, D. C., Nie, Y., Postma, D. S., Laviolette, M., Sandford, A. J., Daley, D. D., Hogg, J. C., Elliott, W. M., Fishbane, N., Timens, W., Hysi, P. G., Kaprio, J., Wilson, J. F., Hui, J., Rawal, R., Schulz, H., Stubbe, B., & 26 othersHayward, C., Polasek, O., Järvelin, M-R., Zhao, J. H., Jarvis, D., Kähönen, M., Franceschini, N., North, K. E., Loth, D. W., Brusselle, G. G., Smith, A. V., Gudnason, V., Bartz, T. M., Wilk, J. B., O'Connor, G. T., Cassano, P. A., Tang, W., Wain, L. V., Artigas, M. S., Gharib, S. A., Strachan, D. P., Sin, D. D., Tobin, M. D., London, S. J., Hall, I. P. & Paré, P. D., Oct 2015, In: The Lancet Respiratory Medicine. 3, 10, p. 782-95 14 p.

    Research output: Contribution to journalArticlepeer-review