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  • 2015

    New genetic loci link adipose and insulin biology to body fat distribution

    Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Lockes, A. E., Maegi, R., Strawbridge, R. J., Pers, T. H., Fischer, K., Justice, A. E., Workalemahu, T., Wu, J. M. W., Buchkovich, M. L., Heard-Costa, N. L., Roman, T. S., Drong, A. W., Song, C., Gustafsson, S., Day, F. R., Esko, T. & 42 others, Fall, T., Kutalik, Z., Luan, J., Randall, J. C., Scherag, A., Vedantam, S., Wood, A. R., Chen, J., Fehrmann, R., Karjalainen, J., Kahali, B., Liu, C-T., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Ehret, G. B., Feitosa, M. F., Hayward, C., Campbell, H., Morris, A. D., Rudan, I., Wilson, J. F., Walker, M., Visscher, P. M., ADIPOGen Consortium, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GEFOS Consortium, GENIE Consortium, GLGC, ICBP, Int Endogene Consortium, LifeLines Cohort Study, MAGIC Investigators, MuTHER Consortium, PAGE Consortium & ReproGen Consortium, 12 Feb 2015, In: Nature. 518, 7538, p. 187-196 10 p.

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  • Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

    Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., Billington, C. K., Kheirallah, A. K., Allen, R., Cook, J. P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D. S., Paré, P. D., Ramasamy, A., Mägi, R., Mihailov, E., Reinmaa, E. & 138 others, Melén, E., O'Connell, J., Frangou, E., Delaneau, O., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., Hall, I. P., Farrall, M., Barroso, I., Anderson, C. A., Botía, J., Vandrocova, J., Guelfi, S., D'Sa, K., Ryten, M., Trabzuni, D., Matarin, M., Hardy, J. A., Weale, M. E., Varghese, V., Forabosco, P., Farmer, A., McGuffin, P., Zgaga, L., Wilson, J. F., Wild, S. H., Campbell, H., Rudan, I., Smith, C., Walker, R., Liu, J. Z., Tozzi, F., Muglia, P., Waterworth, D. M., Pillai, S. G., Yuan, X., Mooser, V., Middleton, L., Kooner, J., Chambers, J. C., Berrettini, W., Knouff, C. W., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Khaw, K. T., Grundy, S., Barter, P., Mahley, R., Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H. E., Rawal, R., Wichmann, H. E., Lamina, C., Dahmen, N., Polasek, O., Kolcic, I., Huffman, J., Campbell, S., Vitart, V., Hayward, C., Wright, A. F., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Epstein, S., Reilly, M. P., Li, M., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Rader, D. J., Ellinghaus, D., Lieb, W., Franke, A., Uda, M., Busonero, F., Terracciano, A., Schlessinger, D., Xiao, X., Scheet, P., St Clair, D., Rujescu, D., Abecasis, G. R., Grabe, H. J., Teumer, A., Völzke, H., Petersmann, A., John, U., Wright, B. J., Thompson, J. R., Balmforth, A. J., Hall, A. S., Samani, N. J., Ahmad, T., Mathew, C. G., Parkes, M., Satsangi, J., Caulfield, M., Munroe, P. B., Dominiczak, A., Worthington, J., Thomson, W., Eyre, S., Barton, A. & Francks, C., 1 Oct 2015, In: The Lancet Respiratory Medicine. 3, 10, p. 769-781 13 p.

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  • Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein

    CHARGE Inflammation working group, 13 Mar 2015, In: PLoS ONE. 10, 3, e0118859.

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  • Recent genomic heritage in Scotland

    Generation Scotland, Amador, C., Huffman, J., Trochet, H., Campbell, A., Porteous, D., Wilson, J. F., Hastie, N., Vitart, V., Hayward, C., Navarro, P. & Haley, C. S., 6 Jun 2015, In: BMC Genomics. 16, 1, 437.

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  • Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    UK BiLEVE, Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M. & 31 others, Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L-P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C-A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A-L., Henderson, J., Navarro, P., Starr, J. M., Wild, S. H., Wright, A. F., Vitart, V., Rudan, I., Deary, I. J., Wilson, J. F., Morris, A. P. & Hayward, C., 4 Dec 2015, In: Nature Communications. 6, p. 8658

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  • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    CHARGE Consortium, Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L. & 31 others, Karjalainen, J., Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H-J., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y-C., Wild, S. H., Wilson, J. F., Campbell, H., Hastie, N., Morris, A. P., Wright, A. F., Hayward, C., Rudan, I. & Vitart, V., Oct 2015, In: PLoS Genetics. 11, 10, p. e1005378

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  • The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape

    Busby, G. B. J., Hellenthal, G., Montinaro, F., Tofanelli, S., Bulayeva, K., Rudan, I., Zemunik, T., Hayward, C., Toncheva, D., Karachanak-Yankova, S., Nesheva, D., Anagnostou, P., Cali, F., Brisighelli, F., Romano, V., Lefranc, G., Buresi, C., Ben Chibani, J., Haj-Khelil, A., Denden, S. & 8 others, Ploski, R., Krajewski, P., Hervig, T., Moen, T., Herrera, R. J., Wilson, J. F., Myers, S. & Capelli, C., 5 Oct 2015, In: Current biology : CB. 25, 19, p. 2518-26 9 p.

    Research output: Contribution to journalArticlepeer-review

  • 2014

    A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

    O'Connell, J., Gurdasani, D., Delaneau, O., Pirastu, N., Ulivi, S., Cocca, M., Traglia, M., Huang, J., Huffman, J. E., Rudan, I., McQuillan, R., Fraser, R. M., Campbell, H., Polasek, O., Asiki, G., Ekoru, K., Hayward, C., Wright, A. F., Vitart, V., Navarro, P. & 7 others, Zagury, J-F., Wilson, J. F., Toniolo, D., Gasparini, P., Soranzo, N., Sandhu, M. S. & Marchini, J., 17 Apr 2014, In: PLoS Genetics. 10, 4, 21 p., e1004234.

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  • A Genetic Atlas of Human Admixture History

    Hellenthal, G., Busby, G. B. J., Band, G., Wilson, J. F., Capelli, C., Falush, D. & Myers, S., 14 Feb 2014, In: Science. 343, 6172, p. 747-751 5 p.

    Research output: Contribution to journalArticlepeer-review

  • Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

    LifeLines Cohort Study Investigato, ICBP, CHARGE Consortium, Global Blood Pressure Genetics Gl, Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. S. & 34 others, van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E., Vitart, V., Fraser, R. M., Huffman, J. E., de Boer, R. A., Schoettker, B., Saum, K-U., McCarthy, M. I., Dupuis, J., Herzig, K-H., Sebert, S., Pouta, A., Laitinen, J., Kleber, M. E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J. A., Acharya, J., Hardy, R., McLachlan, S., Theodoratou, E., Navarro, P., Wright, A. F., Polasek, O., Hayward, C., Wilson, J. F., Rudan, I., Campbell, H. & Price, J. F., Sep 2014, In: The Lancet Diabetes and Endocrinology. 2, 9, p. 719-729 11 p.

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  • Chronotype and sleep duration: The influence of season of assessment

    Allebrandt, K. V., Teder-Laving, M., Kantermann, T., Peters, A., Campbell, H., Rudan, I., Wilson, J. F., Metspalu, A. & Roenneberg, T., 28 Mar 2014, In: Chronobiology international. 31, 5, p. 731-740 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Elect Med Records & Genom eMERGE C, MIGen Consortium, PAGE Consortium, LifeLines Cohort Study, Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., Chun, A. Y., Estrada, K., Luan, J., Kutalik, Z., Amin, N., Buchkovich, M. L., Croteau-Chonka, D. C., Day, F. R., Duan, Y., Fall, T. & 34 others, Fehrmann, R., Ferreira, T., Jackson, A. U., Karjalainen, J., Lo, K. S., Locke, A. E., Maegi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H-J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Fraser, R. M., Bolton, J. L., Hayward, C., McLachlan, S., Wright, A. F., Campbell, H., Morris, A. D., Price, J. F., Rudan, I., Walker, M., Wilson, J. F. & Visscher, P. M., 5 Oct 2014, In: Nature Genetics. 46, 11, p. 1173-1186 14 p.

    Research output: Contribution to journalArticlepeer-review

  • DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

    kConFab investigators, Perry, J. R. B., Hsu, Y-H., Chasman, D. I., Johnson, A. D., Elks, C., Albrecht, E., Andrulis, I. L., Beesley, J., Berenson, G. S., Bergmann, S., Bojesen, S. E., Bolla, M. K., Brown, J., Buring, J. E., Campbell, H., Chang-Claude, J., Chenevix-Trench, G., Corre, T., Couch, F. J. & 31 others, Cox, A., Czene, K., D'adamo, A. P., Davies, G., Deary, I. J., Dennis, J., Easton, D. F., Engelhardt, E. G., Eriksson, J. G., Esko, T., Fasching, P. A., Figueroa, J. D., Flyger, H., Fraser, A., Garcia-Closas, M., Gasparini, P., Gieger, C., Giles, G., Guenel, P., Hägg, S., Hall, P., Hayward, C., Hopper, J., Ingelsson, E., Kardia, S. L. R., Polasek, O., Rudan, I., Wild, S., Wilson, J. F., Wright, A. F. & Zgaga, L., May 2014, In: Human Molecular Genetics. 23, 9, p. 2490-2497 8 p.

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  • Evaluation of Bioelectrical Impedance Analysis for Identifying Overweight Individuals at Increased Cardiometabolic Risk: A Cross-Sectional Study

    Lamb, M. J. E., Byrne, C. D., Wilson, J. F. & Wild, S. H., 22 Sep 2014, In: PLoS ONE. 9, 9, p. e106134

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  • Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    CARe Consortium, Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M. & 31 others, Lahtinen, A. M., Nolte, I. M., Smith, A. V., Bis, J. C., Isaacs, A., Newhouse, S. J., Evans, D. S., Post, W. S., Waggott, D., Lyytikäinen, L-P., Hicks, A. A., Eisele, L., Ellinghaus, D., Hayward, C., Navarro, P., Ulivi, S., Tanaka, T., Tester, D. J., Chatel, S., Gustafsson, S., Kumari, M., Morris, R. W., Naluai, A. T., Padmanabhan, S., Kluttig, A., Strohmer, B., Wright, A. F., Campbell, H., Wild, S. H., Wilson, J. F. & Rudan, I., 22 Jun 2014, In: Nature Genetics. 46, 8, p. 826-836

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

    BMES GWAS Group, Hysi, P. G., Cheng, C-Y., Springelkamp, H., Macgregor, S., Bailey, J. N. C., Wojciechowski, R., Vitart, V., Nag, A., Hewitt, A. W., Höhn, R., Venturini, C., Mirshahi, A., Ramdas, W. D., Thorleifsson, G., Vithana, E., Khor, C-C., Stefansson, A. B., Liao, J., Haines, J. L. & 31 others, Amin, N., Wang, Y. X., Wild, P. S., Ozel, A. B., Li, J. Z., Fleck, B. W., Zeller, T., Staffieri, S. E., Teo, Y-Y., Cuellar-Partida, G., Luo, X., Allingham, R. R., Richards, J. E., Senft, A., Karssen, L. C., Zheng, Y., Bellenguez, C., Xu, L., Iglesias, A. I., Wilson, J. F., Kang, J. H., van Leeuwen, E. M., Jonsson, V., Thorsteinsdottir, U., Despriet, D. D. G., Ennis, S., Moroi, S. E., Martin, N. G., Jansonius, N. M., Yazar, S. & Tai, E-S., Oct 2014, In: Nature Genetics. 46, 10, p. 1126-1130 5 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Generation Scotland, Jul 2014, In: Nature Genetics. 46, 7, p. 669-77 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin

    on behalf of the CORtisol NETwork (CORNET) Consortium, 10 Jul 2014, In: PLoS Genetics. 10, 7, e1004474.

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  • Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2

    Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) Consortium Neurology Working Group, Huang, J., Huffman, J. E., Yamkauchi, M., Trompet, S., Asselbergs, F. W., Sabater-Lleal, M., Trégouët, D-A., Chen, W-M., Smith, N. L., Kleber, M. E., Shin, S-Y., Becker, D. M., Tang, W., Dehghan, A., Johnson, A. D., Truong, V., Folkersen, L., Yang, Q., Oudot-Mellkah, T. & 31 others, Buckley, B. M., Moore, J. H., Williams, F. M. K., Campbell, H., Silbernagel, G., Vitart, V., Rudan, I., Tofler, G. H., Navis, G. J., Destefano, A., Wright, A. F., Chen, M-H., de Craen, A. J. M., Worrall, B. B., Rudnicka, A. R., Rumley, A., Bookman, E. B., Psaty, B. M., Chen, F., Keene, K. L., Franco, O. H., Böhm, B. O., Uitterlinden, A. G., Carter, A. M., Jukema, J. W., Sattar, N., Bis, J. C., Ikram, M. A., Wilson, J. F., Polasek, O. & Hayward, C., 27 Feb 2014, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 34, 5, p. 1093-101 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

    DCCT EDIC Res Grp, Simpson, C. L., Wojciechowski, R., Oexle, K., Murgia, F., Portas, L., Li, X., Verhoeven, V. J. M., Vitart, V., Schache, M., Hosseini, S. M., Hysi, P. G., Raffel, L. J., Cotch, M. F., Chew, E., Klein, B. E. K., Klein, R., Wong, T. Y., Van Duijn, C. M., Mitchell, R. & 31 others, Saw, S. M., Fossarello, M., Wang, J. J., Polasek, O., Campbell, H., Rudan, I., Oostra, B. A., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Amin, N., Karssen, L. C., Vingerling, J. R., Doering, A., Bettecken, T., Bencic, G., Gieger, C., Wichmann, H. -E., Wilson, J. F., Venturini, C., Fleck, B., Cumberland, P. M., Rahi, J. S., Hammond, C. J., Hayward, C., Wright, A. F., Paterson, A. D., Baird, P. N., Klaver, C. C. W., Rotter, J. I. & Pirastu, M., 18 Sep 2014, In: PLoS ONE. 9, 9, 19 p., 107110.

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  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S. & 35 others, Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B., Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., Boehm, B. O., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Chan, J. C. N., Chang, L-C., Chang, T-J., Chang, Y-C., Fraser, R. M., Hayward, C., Morris, A., Navarro, P., Price, J. F., Rudan, I., Wilson, J. F. & Zhang, R., Mar 2014, In: Nature Genetics. 46, 3, p. 234-244 13 p.

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  • Glycans Are a Novel Biomarker of Chronological and Biological Ages

    Kristic, J., Vuckovic, F., Menni, C., Klaric, L., Keser, T., Beceheli, I., Pucic-Bakovic, M., Novokmet, M., Mangino, M., Thaqi, K., Rudan, P., Novokmet, N., Sarac, J., Missoni, S., Kolcic, I., Polasek, O., Rudan, I., Campbell, H., Hayward, C., Aulchenko, Y. & 7 others, Valdes, A., Wilson, J. F., Gornik, O., Primorac, D., Zoldos, V., Spector, T. & Lauc, G., Jul 2014, In: Journal of Gerontology: Medical Sciences. 69, 7, p. 779-789 11 p.

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  • Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

    van den Berg, S. M., de Moor, M. H. M., McGue, M., Pettersson, E., Terracciano, A., Verweij, K. J. H., Amin, N., Derringer, J., Esko, T., van Grootheest, G., Hansell, N. K., Huffman, J., Konte, B., Lahti, J., Luciano, M., Matteson, L. K., Viktorin, A., Wouda, J., Agrawal, A., Allik, J. & 68 others, Bierut, L., Broms, U., Campbell, H., Smith, G. D., Eriksson, J. G., Ferrucci, L., Franke, B., Fox, J-P., de Geus, E. J. C., Giegling, I., Gow, A. J., Grucza, R., Hartmann, A. M., Heath, A. C., Heikkilä, K., Iacono, W. G., Janzing, J., Jokela, M., Kiemeney, L., Lehtimäki, T., Madden, P. A. F., Magnusson, P. K. E., Northstone, K., Nutile, T., Ouwens, K. G., Palotie, A., Pattie, A., Pesonen, A-K., Polasek, O., Pulkkinen, L., Pulkki-Råback, L., Raitakari, O. T., Realo, A., Rose, R. J., Ruggiero, D., Seppälä, I., Slutske, W. S., Smyth, D. C., Sorice, R., Starr, J. M., Sutin, A. R., Tanaka, T., Verhagen, J., Vermeulen, S., Vuoksimaa, E., Widen, E., Willemsen, G., Wright, M. J., Zgaga, L., Rujescu, D., Metspalu, A., Wilson, J. F., Ciullo, M., Hayward, C., Rudan, I., Deary, I. J., Räikkönen, K., Arias Vasquez, A., Costa, P. T., Keltikangas-Järvinen, L., van Duijn, C. M., Penninx, B. W. J. H., Krueger, R. F., Evans, D. M., Kaprio, J., Pedersen, N. L., Martin, N. G. & Boomsma, D. I., Jul 2014, In: Behavior Genetics. 44, 4, p. 295-313 19 p.

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  • No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

    Baumert, J., Huang, J., McKnight, B., Sabater-Lleal, M., Steri, M., Chu, A. Y., Trompet, S., Lopez, L. M., Fornage, M., Teumer, A., Tang, W., Rudnicka, A. R., Mälarstig, A., Hottenga, J-J., Kavousi, M., Lahti, J., Tanaka, T., Hayward, C., Huffman, J. E., Morange, P-E. & 83 others, Rose, L. M., Basu, S., Rumley, A., Stott, D. J., Buckley, B. M., de Craen, A. J. M., Sanna, S., Masala, M., Biffar, R., Homuth, G., Silveira, A., Sennblad, B., Goel, A., Watkins, H., Müller-Nurasyid, M., Rückerl, R., Taylor, K., Chen, M-H., de Geus, E. J. C., Hofman, A., Witteman, J. C. M., de Maat, M. P. M., Palotie, A., Davies, G., Siscovick, D. S., Kolcic, I., Wild, S. H., Song, J., McArdle, W. L., Ford, I., Sattar, N., Schlessinger, D., Grotevendt, A., Franzosi, M. G., Illig, T., Waldenberger, M., Lumley, T., Tofler, G. H., Willemsen, G., Uitterlinden, A. G., Rivadeneira, F., Räikkönen, K., Chasman, D. I., Folsom, A. R., Lowe, G. D., Westendorp, R. G. J., Slagboom, P. E., Cucca, F., Wallaschofski, H., Strawbridge, R. J., Seedorf, U., Koenig, W., Bis, J. C., Mukamal, K. J., van Dongen, J., Widen, E., Franco, O. H., Starr, J. M., Liu, K., Ferrucci, L., Polasek, O., Wilson, J. F., Oudot-Mellakh, T., Campbell, H., Navarro, P., Bandinelli, S., Eriksson, J., Boomsma, D. I., Dehghan, A., Clarke, R., Hamsten, A., Boerwinkle, E., Jukema, J. W., Naitza, S., Ridker, P. M., Völzke, H., Deary, I. J., Reiner, A. P., Trégouët, D-A., O'Donnell, C. J., Strachan, D. P., Peters, A. & Smith, N. L., 31 Dec 2014, In: PLoS ONE. 9, 12, p. e111156

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  • Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis

    Hauser, B., Riches, P. L., Wilson, J. F., Horne, A. E. & Ralston, S. H., Oct 2014, In: Rheumatology. 53, 10, p. 1759-1766

    Research output: Contribution to journalArticlepeer-review

  • Quality control and conduct of genome-wide association meta-analyses

    Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Maegi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpelainen, T. O., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 10 others, Loos, R. J. F., Genetic Invest Anthropometric Trai, Bolton, J., Campbell, H., Fowkes, G., Fraser, R., Price, J., Rudan, I., Wild, S. & Wilson, J., 24 Apr 2014, In: Nature Protocols. 9, 5, p. 1192-1212 21 p.

    Research output: Contribution to journalArticlepeer-review

  • The association between galactosylation of immunoglobulin G and body mass index

    Perkovic, M. N., Bakovic, M. P., Kristic, J., Novokmet, M., Huffman, J. E., Vitart, V., Hayward, C., Rudan, I., Wilson, J. F., Campbell, H., Polasek, O., Lauc, G. & Pivac, N., 3 Jan 2014, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 48, p. 20-25 6 p.

    Research output: Contribution to journalArticlepeer-review

  • 2013

    A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

    Allebrandt, K. V., Amin, N., Mueller-Myhsok, B., Esko, T., Teder-Laving, M., Azevedo, R. V. D. M., Hayward, C., van Mill, J., Vogelzangs, N., Green, E. W., Melville, S. A., Lichtner, P., Wichmann, H-E., Oostra, B. A., Janssens, A. C. J. W., Campbell, H., Wilson, J. F., Hicks, A. A., Pramstaller, P. P., Dogas, Z. & 8 others, Rudan, I., Merrow, M., Penninx, B., Kyriacou, C. P., Metspalu, A., van Duijn, C. M., Meitinger, T. & Roenneberg, T., Jan 2013, In: Molecular Psychiatry. 18, 1, p. 122-132 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Beecham, A. H., Patsopoulos, N. A., Xifara, D. K., Davis, M. F., Kemppinen, A., Cotsapas, C., Shah, T. S., Spencer, C., Booth, D., Goris, A., Oturai, A., Saarela, J., Fontaine, B., Hemmer, B., Martin, C., Zipp, F., D'Alfonso, S., Martinelli-Boneschi, F., Taylor, B., Harbo, H. F. & 31 others, Kockum, I., Hillert, J., Olsson, T., Ban, M., Oksenberg, J. R., Hintzen, R., Barcellos, L. F., Agliardi, C., Alfredsson, L., Alizadeh, M., Anderson, C., Andrews, R., Søndergaard, H. B., Baker, A., Band, G., Baranzini, S. E., Barizzone, N., Barrett, J., Bellenguez, C., Bergamaschi, L., Bernardinelli, L., Berthele, A., Biberacher, V., Binder, T. M. C., Blackburn, H., Bomfim, I. L., Brambilla, P., Broadley, S., Wilson, J. F., International Multiple Sclerosis Genetics Consortium (IMSGC) & Henderson, P., Nov 2013, In: Nature Genetics. 45, 11, p. 1353-60 8 p.

    Research output: Contribution to journalArticlepeer-review

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  • Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

    Fernández-Rhodes, L., Demerath, E. W., Cousminer, D. L., Tao, R., Dreyfus, J. G., Esko, T., Smith, A. V., Gudnason, V., Harris, T. B., Launer, L., McArdle, P. F., Yerges-Armstrong, L. M., Elks, C. E., Strachan, D. P., Kutalik, Z., Vollenweider, P., Feenstra, B., Boyd, H. A., Metspalu, A., Mihailov, E. & 55 others, Broer, L., Zillikens, M. C., Oostra, B., van Duijn, C. M., Lunetta, K. L., Perry, J. R. B., Murray, A., Koller, D. L., Lai, D., Corre, T., Toniolo, D., Albrecht, E., Stöckl, D., Grallert, H., Gieger, C., Hayward, C., Polasek, O., Rudan, I., Wilson, J. F., He, C., Kraft, P., Hu, F. B., Hunter, D. J., Hottenga, J-J., Willemsen, G., Boomsma, D. I., Byrne, E. M., Martin, N. G., Montgomery, G. W., Warrington, N. M., Pennell, C. E., Stolk, L., Visser, J. A., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Lin, P., Fisher, S. L., Bierut, L. J., Crisponi, L., Porcu, E., Mangino, M., Zhai, G., Spector, T. D., Buring, J. E., Rose, L. M., Ridker, P. M., Poole, C., Hirschhorn, J. N., Murabito, J. M., Chasman, D. I., Widen, E., North, K. E., Ong, K. K. & Franceschini, N., 1 Aug 2013, In: American Journal of Epidemiology. 178, 3, p. 451-460 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

    Thun, G. A., Imboden, M., Ferrarotti, I., Kumar, A., Obeidat, M., Zorzetto, M., Haun, M., Curjuric, I., Couto Alves, A., Jackson, V. E., Albrecht, E., Ried, J. S., Teumer, A., Lopez, L. M., Huffman, J. E., Enroth, S., Bossé, Y., Hao, K., Timens, W., Gyllensten, U. & 23 others, Polasek, O., Wilson, J. F., Rudan, I., Hayward, C., Sandford, A. J., Deary, I. J., Koch, B., Reischl, E., Schulz, H., Hui, J., James, A. L., Rochat, T., Russi, E. W., Jarvelin, M-R., Strachan, D. P., Hall, I. P., Tobin, M. D., Dahl, M., Fallgaard Nielsen, S., Nordestgaard, B. G., Kronenberg, F., Luisetti, M. & Probst-Hensch, N. M., Aug 2013, In: PLoS Genetics. 9, 8, 16 p., e1003585.

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  • Common variants associated with plasma triglycerides and risk for coronary artery disease

    Do, R., Willer, C. J., Schmidt, E. M., Sengupta, S., Gao, C., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M. L., Mora, S., Beckmann, J. S., Bragg-Gresham, J. L., Chang, H-Y., Demirkan, A., Den Hertog, H. M., Donnelly, L. A., Ehret, G. B., Esko, T. & 243 others, Feitosa, M. F., Ferreira, T., Fischer, K., Fontanillas, P., Fraser, R. M., Freitag, D. F., Gurdasani, D., Heikkilä, K., Hyppönen, E., Isaacs, A., Jackson, A. U., Johansson, A., Johnson, T., Kaakinen, M., Kettunen, J., Kleber, M. E., Li, X., Luan, J., Lyytikäinen, L-P., Magnusson, P. K. E., Mangino, M., Mihailov, E., Montasser, M. E., Müller-Nurasyid, M., Nolte, I. M., O'Connell, J. R., Palmer, C. D., Perola, M., Petersen, A-K., Sanna, S., Saxena, R., Service, S. K., Shah, S., Shungin, D., Sidore, C., Song, C., Strawbridge, R. J., Surakka, I., Tanaka, T., Teslovich, T. M., Thorleifsson, G., Van den Herik, E. G., Voight, B. F., Volcik, K. A., Waite, L. L., Wong, A., Wu, Y., Zhang, W., Absher, D., Asiki, G., Barroso, I., Been, L. F., Bolton, J. L., Bonnycastle, L. L., Brambilla, P., Burnett, M. S., Cesana, G., Dimitriou, M., Doney, A. S. F., Döring, A., Elliott, P., Epstein, S. E., Eyjolfsson, G. I., Gigante, B., Goodarzi, M. O., Grallert, H., Gravito, M. L., Groves, C. J., Hallmans, G., Hartikainen, A-L., Hayward, C., Hernandez, D., Hicks, A. A., Holm, H., Hung, Y-J., Illig, T., Jones, M. R., Kaleebu, P., Kastelein, J. J. P., Khaw, K-T., Kim, E., Klopp, N., Komulainen, P., Kumari, M., Langenberg, C., Lehtimäki, T., Lin, S-Y., Lindström, J., Loos, R. J. F., Mach, F., McArdle, W. L., Meisinger, C., Mitchell, B. D., Müller, G., Nagaraja, R., Narisu, N., Nieminen, T. V. M., Nsubuga, R. N., Olafsson, I., Ong, K. K., Palotie, A., Papamarkou, T., Pomilla, C., Pouta, A., Rader, D. J., Reilly, M. P., Ridker, P. M., Rivadeneira, F., Rudan, I., Ruokonen, A., Samani, N., Scharnagl, H., Seeley, J., Silander, K., Stančáková, A., Stirrups, K., Swift, A. J., Tiret, L., Uitterlinden, A. G., van Pelt, L. J., Vedantam, S., Wainwright, N., Wijmenga, C., Wild, S. H., Willemsen, G., Wilsgaard, T., Wilson, J. F., Young, E. H., Zhao, J. H., Adair, L. S., Arveiler, D., Assimes, T. L., Bandinelli, S., Bennett, F., Bochud, M., Boehm, B. O., Boomsma, D. I., Borecki, I. B., Bornstein, S. R., Bovet, P., Burnier, M., Campbell, H., Chakravarti, A., Chambers, J. C., Chen, Y-D. I., Collins, F. S., Cooper, R. S., Danesh, J., Dedoussis, G., de Faire, U., Feranil, A. B., Ferrières, J., Ferrucci, L., Freimer, N. B., Gieger, C., Groop, L. C., Gudnason, V., Gyllensten, U., Hamsten, A., Harris, T. B., Hingorani, A., Hirschhorn, J. N., Hofman, A., Hovingh, G. K., Hsiung, C. A., Humphries, S. E., Hunt, S. C., Hveem, K., Iribarren, C., Järvelin, M-R., Jula, A., Kähönen, M., Kaprio, J., Kesäniemi, A., Kivimaki, M., Kooner, J. S., Koudstaal, P. J., Krauss, R. M., Kuh, D., Kuusisto, J., Kyvik, K. O., Laakso, M., Lakka, T. A., Lind, L., Lindgren, C. M., Martin, N. G., März, W., McCarthy, M. I., McKenzie, C. A., Meneton, P., Metspalu, A., Moilanen, L., Morris, A., Munroe, P. B., Njølstad, I., Pedersen, N. L., Power, C., Pramstaller, P. P., Price, J. F., Psaty, B. M., Quertermous, T., Rauramaa, R., Saleheen, D., Salomaa, V., Sanghera, D. K., Saramies, J., Schwarz, P. E. H., Sheu, W. H-H., Shuldiner, A. R., Siegbahn, A., Spector, T. D., Stefansson, K., Strachan, D. P., Tayo, B. O., Tremoli, E., Tuomilehto, J., Uusitupa, M., van Duijn, C. M., Vollenweider, P., Wallentin, L., Wareham, N. J., Whitfield, J. B., Wolffenbuttel, B. H. R., Altshuler, D., Ordovas, J. M., Boerwinkle, E., Palmer, C. N. A., Thorsteinsdottir, U., Chasman, D. I., Rotter, J. I., Franks, P. W., Ripatti, S., Cupples, L. A., Sandhu, M. S., Rich, S. S., Boehnke, M., Deloukas, P., Mohlke, K. L., Ingelsson, E., Abecasis, G. R., Daly, M. J., Neale, B. M. & Kathiresan, S., Nov 2013, In: Nature Genetics. 45, 11, p. 1345-52 8 p.

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  • Common Variants in Mendelian Kidney Disease Genes and Their Association with Renal Function

    Parsa, A., Fuchsberger, C., Köttgen, A., O'Seaghdha, C. M., Pattaro, C., de Andrade, M., Chasman, D. I., Teumer, A., Endlich, K., Olden, M., Chen, M-H., Tin, A., Kim, Y. J., Taliun, D., Li, M., Feitosa, M., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C. & 139 others, Glazer, N., Isaacs, A., Rao, M., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Tönjes, A., Dehghan, A., Couraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Hofer, E., Hu, F., Demirkan, A., Oostra, B. A., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Döring, A., Wichmann, H-E., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Colhoun, H., Doney, A., Robino, A., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G-A., Paulweber, B., Haun, M., Sala, C., Mitchell, R., Ciullo, M., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Bochud, M., Heid, I. M., Siscovick, D. S., Fox, C. S., Kao, W. L. & Böger, C. A., Dec 2013, In: Journal of the American Society of Nephrology. 24, 12, p. 2105-2117 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Discovery and refinement of loci associated with lipid levels

    Global Lipids Genetics Consortium, Willer, C. J., Schmidt, E. M., Sengupta, S., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M. L., Mora, S., Beckmann, J. S., Bragg-Gresham, J. L., Chang, H-Y., Demirkan, A., Den Hertog, H. M., Do, R., Donnelly, L. A., Ehret, G. B., Esko, T. & 31 others, Feitosa, M. F., Ferreira, T., Fischer, K., Fontanillas, P., Fraser, R. M., Freitag, D. F., Gurdasani, D., Heikkilä, K., Hyppönen, E., Isaacs, A., Jackson, A. U., Johansson, A., Johnson, T., Kaakinen, M., Kettunen, J., Kleber, M. E., Li, X., Luan, J., Lyytikäinen, L-P., Magnusson, P. K. E., Mangino, M., Mihailov, E., Montasser, M. E., Bolton, J. L., Hayward, C., Rudan, I., Wild, S. H., Wilson, J. F., Campbell, H., Morris, A. & Price, J. F., Nov 2013, In: Nature Genetics. 45, 11, p. 1274-83 10 p.

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  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

    LifeLines Cohort Study, Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, R. P. S., Brown, M. J. & 31 others, Gaffo, A. L., Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., van der Harst, P., Li, X., Kleber, M. E., Wild, S. H., Tenesa, A., Navarro, P., Hastie, N., Davies, G., Gow, A. J., Wilson, J. F., Farrington, S. M., Theodoratou, E., Polasek, O., Campbell, H., Rudan, I., Deary, I. J., Wright, A. F. & Dunlop, M. G., Feb 2013, In: Nature Genetics. 45, 2, p. 145-154 10 p.

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  • Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

    NEIGHBOR Consortium, Lu, Y., Vitart, V., Burdon, K. P., Khor, C. C., Bykhovskaya, Y., Mirshahi, A., Hewitt, A. W., Koehn, D., Hysi, P. G., Ramdas, W. D., Zeller, T., Vithana, E. N., Cornes, B. K., Tay, W-T., Tai, E. S., Cheng, C-Y., Liu, J., Foo, J-N., Saw, S. M. & 31 others, Thorleifsson, G., Stefansson, K., Dimasi, D. P., Mills, R. A., Mountain, J., Ang, W., Hoehn, R., Verhoeven, V. J. M., Grus, F., Wolfs, R., Castagne, R., Lackner, K. J., Springelkamp, H., Yang, J., Jonasson, F., Leung, D. Y. L., Chen, L. J., Tham, C. C. Y., Rudan, I., Vatavuk, Z., Hayward, C., Gibson, J., Cree, A. J., Macleod, A., Ennis, S., Polasek, O., Campbell, H., Wilson, J. F., Viswanathan, A. C., Fleck, B. & Wright, A. F., Feb 2013, In: Nature Genetics. 45, 2, p. 155-163 9 p.

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  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

    CREAM, Diabet Control Complications Trial, WTCCC2, Fuchs' Genetics Multi-Ctr Study Gr, Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Hoehn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P. & 34 others, St Pourcain, B., Simpson, C. L., Makela, K-M., Lehtimaki, T., Kahonen, M., Paterson, A. D., Hosseini, S. M., Wong, H. S., Xu, L., Jonas, J. B., Parssinen, O., Wedenoja, J., Yip, S. P., Ho, D. W. H., Pang, C. P., Chen, L. J., Burdon, K. P., Craig, J. E., Klein, B. E. K., Klein, R., Haller, T., Metspalu, A., Khor, C-C., Tai, E-S., Aung, T., Vithana, E., Tay, W-T., Barathi, V. A., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F., Fleck, B. & Vitart, V., Mar 2013, In: Nature Genetics. 45, 3, p. 314-318 5 p.

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  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W. & 302 others, Wood, A. R., Workalemahu, T., Hu, Y-J., Lee, S. H., Liang, L., Lin, D-Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., den Heijer, M., Eklund, N., Fischer, K., Goel, A., Hottenga, J-J., Huffman, J. E., Jarick, I., Johansson, A., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Collins, F. S., Connell, J. M., Cookson, W. O., de Faire, U., de Vegt, F., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A-L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J-O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K-T., Kivimäki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M-L., Lorentzon, M., Madden, P. A., Magnusson, P. K., Manunta, P., Marek, D., März, W., Mateo Leach, I., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N. A., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S-Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stančáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D-A., Tremoli, E., Van der Klauw, M. M., van Meurs, J. B. J., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C. M., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M-R., Jöckel, K-H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H-E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe, F., Moffatt, M. F., Mohlke, K. L., O'Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., van Duijn, C. M., Visscher, P. M., Di Blasio, A. M., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E., Loos, R. J. F. & Ingelsson, E., May 2013, In: Nature Genetics. 45, 5, p. 501-512 12 p.

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  • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

    The LifeLines Cohort Study, Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H-J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, B. Z., Amin, N., Barnard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A. & 31 others, Davies, G., de Leeuw, C., Eklund, N., Evans, D. S., Ferhmann, R., Fischer, K., Gieger, C., Gjessing, H. K., Hägg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P., Jugessur, A., Kaakinen, M., Kanoni, S., Karjalainen, J., Kolcic, I., Vitart, V., Campbell, H., Deary, I. J., Hastie, N. D., Liewald, D. C., Rudan, I., Starr, J. M., Wilson, J. F., Wright, A. F. & Visscher, P. M., 21 Jun 2013, In: Science. 340, 6139, p. 1467-1471 5 p.

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  • Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome

    Huang, Y., Hidalgo-Bravo, A., Zhang, E., Cotton, V. E., Mendez-Bermudez, A., Wig, G., Medina-Calzada, Z., Neumann, R., Jeffreys, A. J., Winney, B., Wilson, J. F., Clark, D. A., Dyer, M. J. & Royle, N. J., 19 Sep 2013, In: Nucleic Acids Research.

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  • Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

    Global BPgen Consortium, den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P. & 31 others, Bochud, M., Boucher, G., Cornelis, M. C., Gudbjartsson, D., Hadley, D., van der Harst, P., Hayward, C., den Heijer, M., Igl, W., Jackson, A. U., Kutalik, Z., Luan, J., Kemp, J. P., Kristiansson, K., Ladenvall, C., Lorentzon, M., Montasser, M. E., Njajou, O. T., O'Reilly, P. F., Padmanabhan, S., St Pourcain, B., Rankinen, T., Salo, P., Tanaka, T., Timpson, N. J., Vitart, V., Navarro, P., Polasek, O., Wild, S. H., Wilson, J. F. & Rudan, I., Jun 2013, In: Nature Genetics. 45, 6, p. 621- 14 p.

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  • Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies

    Joshi, P., Prendergast, J., Fraser, R. M., Huffman, J. E., Vitart, V., Hayward, C., McQuillan, R., Glodzik, D., Polašek, O., Hastie, N. D., Rudan, I., Campbell, H., Wright, A. F., Haley, C. S., Wilson, J. F. & Navarro, P., 16 Jul 2013, In: PLoS ONE. 8, 7, 6 p., e68604.

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  • Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

    Lauc, G., Huffman, J. E., Pučić, M., Zgaga, L., Adamczyk, B., Mužinić, A., Novokmet, M., Polsek, O., Gornik, O., Krištić, J., Keser, T., Vitart, V., Scheijen, B., Uh, H-W., Molokhia, M., Patrick, A. L., McKeigue, P., Kolčić, I., Lukić, I. K., Swann, O. & 19 others, van Leeuwen, F. N., Ruhaak, L. R., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Deelder, A. M., Zeng, Q., Wang, W., Hastie, N. D., Gyllensten, U., Wilson, J. F., Wuhrer, M., Wright, A. F., Rudd, P. M., Hayward, C., Aulchenko, Y., Campbell, H. & Rudan, I., 31 Jan 2013, In: PLoS Genetics. 9, 1, e1003225.

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  • Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

    SUNLIGHT consortium & The GEFOS consortium, Sep 2013, In: PLoS Genetics. 9, 9, 13 p., e1003796.

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  • Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

    DCCT/EDIC Research Group, Stambolian, D., Wojciechowski, R., Oexle, K., Pirastu, M., Li, X., Raffel, L. J., Cotch, M. F., Chew, E. Y., Klein, B., Klein, R., Wong, T. Y., Simpson, C. L., Klaver, C. C. W., van Duijn, C. M., Verhoeven, V. J. M., Baird, P. N., Vitart, V., Paterson, A. D., Mitchell, P. & 31 others, Saw, S. M., Fossarello, M., Kazmierkiewicz, K., Murgia, F., Portas, L., Schache, M., Richardson, A., Xie, J., Wang, J. J., Rochtchina, E., Viswanathan, A. C., Hayward, C., Wright, A. F., Polasek, O., Campbell, H., Rudan, I., Oostra, B. A., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Amin, N., Karssen, L. C., Vingerling, J. R., Hosseini, S. M., Döring, A., Bettecken, T., Vatavuk, Z., Gieger, C., Wichmann, H-E., Wilson, J. F. & Fleck, B., 1 Jul 2013, In: Human Molecular Genetics. 22, 13, p. 2754-2764 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

    VTE Consortium, STROKE Consortium, WTCCC2, CD4 Consortium, CARDIoGRAM Consortium, Sabater-Lleal, M., Huang, J., Chasman, D., Naitza, S., Dehghan, A., Johnson, A. D., Teumer, A., Reiner, A. P., Folkersen, L., Basu, S., Rudnicka, A. R., Trompet, S., Malarstig, A., Baumert, J., Bis, J. C. & 35 others, Guo, X., Hottenga, J. J., Shin, S-Y., Lopez, L. M., Lahti, J., Tanaka, T., Yanek, L. R., Oudot-Mellakh, T., Wilson, J. F., Navarro, P., Huffman, J. E., Zemunik, T., Redline, S., Mehra, R., Pulanic, D., Rudan, I., Wright, A. F., Kolcic, I., Polasek, O., Wild, S. H., Campbell, H., Curb, J. D., Wallace, R., Liu, S., Eaton, C. B., Becker, D. M., Becker, L. C., Bandinelli, S., Davies, G., Harris, S. E., Liewald, D. C., Starr, J. M., Grant, P. J., Deary, I. J. & Hayward, C., 17 Sep 2013, In: Circulation. 128, 12, p. 1310-1324 15 p.

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  • Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile

    Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kolcic, I. & 20 others, Hansen, T., Gasperikova, D., Tjora, E., Strachan, M. W. J., Nielsen, T., Stanik, J., Klimes, I., Pedersen, O. B., Njølstad, P. R., Wild, S. H., Gyllensten, U., Gornik, O., Wilson, J. F., Hastie, N. D., Campbell, H., McCarthy, M. I., Rudd, P. M., Owen, K. R., Lauc, G. & Wright, A. F., Apr 2013, In: Diabetes . 62, 4, p. 1329-1337

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  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

    Early Growth Genetics EGG, MAGIC, Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimaki, T., Kreiner-Moller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E. & 31 others, Pfab, T., Barton, S. J., Shields, B. M., Kerkhof, M., van Leeuwen, E. M., Fulford, A. J., Kutalik, Z., Zhao, J. H., den Hoed, M., Mahajan, A., Lindi, V., Goh, L-K., Hottenga, J-J., Wu, Y., Raitakari, O. T., Harder, M. N., Meirhaeghe, A., Ntalla, I., Salem, R. M., Jameson, K. A., Zhou, K., Monies, D. M., Lagou, V., Kirin, M., Heikkinen, J., Adair, L. S., Alkuraya, F. S., Al-Odaib, A., Amouyel, P., Andersson, E. A. & Wilson, J. F., Jan 2013, In: Nature Genetics. 45, 1, p. 76-U115 10 p.

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