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  • 2013

    Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

    SUNLIGHT consortium & The GEFOS consortium, Sept 2013, In: PLoS Genetics. 9, 9, 13 p., e1003796.

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  • Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

    Consortium for Refractive Error and Myopia, Cheng, C-Y., Schache, M., Ikram, M. K., Young, T. L., Guggenheim, J. A., Vitart, V., Macgregor, S., Verhoeven, V. J. M., Barathi, V. A., Liao, J., Hysi, P. G., Bailey-Wilson, J. E., St Pourcain, B., Kemp, J. P., McMahon, G., Timpson, N. J., Evans, D. M., Montgomery, G. W., Mishra, A., & 31 othersWang, Y. X., Wang, J. J., Rochtchina, E., Polasek, O., Wright, A. F., Amin, N., van Leeuwen, E. M., Wilson, J. F., Pennell, C. E., van Duijn, C. M., de Jong, P. T. V. M., Vingerling, J. R., Zhou, X., Chen, P., Li, R., Tay, W-T., Zheng, Y., Chew, M., Burdon, K. P., Craig, J. E., Iyengar, S. K., Igo, R. P., Lass, J. H., Chew, E. Y., Haller, T., Mihailov, E., Metspalu, A., Wedenoja, J., Campbell, H., Fleck, B. & Rudan, I., 8 Aug 2013, In: American Journal of Human Genetics. 93, 2, p. 264-77 14 p.

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  • Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

    Fernández-Rhodes, L., Demerath, E. W., Cousminer, D. L., Tao, R., Dreyfus, J. G., Esko, T., Smith, A. V., Gudnason, V., Harris, T. B., Launer, L., McArdle, P. F., Yerges-Armstrong, L. M., Elks, C. E., Strachan, D. P., Kutalik, Z., Vollenweider, P., Feenstra, B., Boyd, H. A., Metspalu, A., Mihailov, E., & 55 othersBroer, L., Zillikens, M. C., Oostra, B., van Duijn, C. M., Lunetta, K. L., Perry, J. R. B., Murray, A., Koller, D. L., Lai, D., Corre, T., Toniolo, D., Albrecht, E., Stöckl, D., Grallert, H., Gieger, C., Hayward, C., Polasek, O., Rudan, I., Wilson, J. F., He, C., Kraft, P., Hu, F. B., Hunter, D. J., Hottenga, J-J., Willemsen, G., Boomsma, D. I., Byrne, E. M., Martin, N. G., Montgomery, G. W., Warrington, N. M., Pennell, C. E., Stolk, L., Visser, J. A., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Lin, P., Fisher, S. L., Bierut, L. J., Crisponi, L., Porcu, E., Mangino, M., Zhai, G., Spector, T. D., Buring, J. E., Rose, L. M., Ridker, P. M., Poole, C., Hirschhorn, J. N., Murabito, J. M., Chasman, D. I., Widen, E., North, K. E., Ong, K. K. & Franceschini, N., 1 Aug 2013, In: American Journal of Epidemiology. 178, 3, p. 451-460 10 p.

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  • Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

    Thun, G. A., Imboden, M., Ferrarotti, I., Kumar, A., Obeidat, M., Zorzetto, M., Haun, M., Curjuric, I., Couto Alves, A., Jackson, V. E., Albrecht, E., Ried, J. S., Teumer, A., Lopez, L. M., Huffman, J. E., Enroth, S., Bossé, Y., Hao, K., Timens, W., Gyllensten, U., & 23 othersPolasek, O., Wilson, J. F., Rudan, I., Hayward, C., Sandford, A. J., Deary, I. J., Koch, B., Reischl, E., Schulz, H., Hui, J., James, A. L., Rochat, T., Russi, E. W., Jarvelin, M-R., Strachan, D. P., Hall, I. P., Tobin, M. D., Dahl, M., Fallgaard Nielsen, S., Nordestgaard, B. G., Kronenberg, F., Luisetti, M. & Probst-Hensch, N. M., Aug 2013, In: PLoS Genetics. 9, 8, 16 p., e1003585.

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  • Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies

    Joshi, P., Prendergast, J., Fraser, R. M., Huffman, J. E., Vitart, V., Hayward, C., McQuillan, R., Glodzik, D., Polašek, O., Hastie, N. D., Rudan, I., Campbell, H., Wright, A. F., Haley, C. S., Wilson, J. F. & Navarro, P., 16 Jul 2013, In: PLoS ONE. 8, 7, 6 p., e68604.

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  • Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

    DCCT/EDIC Research Group, Stambolian, D., Wojciechowski, R., Oexle, K., Pirastu, M., Li, X., Raffel, L. J., Cotch, M. F., Chew, E. Y., Klein, B., Klein, R., Wong, T. Y., Simpson, C. L., Klaver, C. C. W., van Duijn, C. M., Verhoeven, V. J. M., Baird, P. N., Vitart, V., Paterson, A. D., Mitchell, P., & 31 othersSaw, S. M., Fossarello, M., Kazmierkiewicz, K., Murgia, F., Portas, L., Schache, M., Richardson, A., Xie, J., Wang, J. J., Rochtchina, E., Viswanathan, A. C., Hayward, C., Wright, A. F., Polasek, O., Campbell, H., Rudan, I., Oostra, B. A., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Amin, N., Karssen, L. C., Vingerling, J. R., Hosseini, S. M., Döring, A., Bettecken, T., Vatavuk, Z., Gieger, C., Wichmann, H-E., Wilson, J. F. & Fleck, B., 1 Jul 2013, In: Human Molecular Genetics. 22, 13, p. 2754-2764 11 p.

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  • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

    The LifeLines Cohort Study, Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H-J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, B. Z., Amin, N., Barnard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A., & 31 othersDavies, G., de Leeuw, C., Eklund, N., Evans, D. S., Ferhmann, R., Fischer, K., Gieger, C., Gjessing, H. K., Hägg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P., Jugessur, A., Kaakinen, M., Kanoni, S., Karjalainen, J., Kolcic, I., Vitart, V., Campbell, H., Deary, I. J., Hastie, N. D., Liewald, D. C., Rudan, I., Starr, J. M., Wilson, J. F., Wright, A. F. & Visscher, P. M., 21 Jun 2013, In: Science. 340, 6139, p. 1467-1471 5 p.

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  • Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

    Global BPgen Consortium, den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., & 31 othersBochud, M., Boucher, G., Cornelis, M. C., Gudbjartsson, D., Hadley, D., van der Harst, P., Hayward, C., den Heijer, M., Igl, W., Jackson, A. U., Kutalik, Z., Luan, J., Kemp, J. P., Kristiansson, K., Ladenvall, C., Lorentzon, M., Montasser, M. E., Njajou, O. T., O'Reilly, P. F., Padmanabhan, S., St Pourcain, B., Rankinen, T., Salo, P., Tanaka, T., Timpson, N. J., Vitart, V., Navarro, P., Polasek, O., Wild, S. H., Wilson, J. F. & Rudan, I., Jun 2013, In: Nature Genetics. 45, 6, p. 621- 14 p.

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  • Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

    DIAGRAM Consortium, Randall, J. C., Winkler, T. W., Kutalik, Z., Berndt, S. I., Jackson, A. U., Monda, K. L., Kilpeläinen, T. O., Esko, T., Mägi, R., Li, S., Workalemahu, T., Feitosa, M. F., Croteau-Chonka, D. C., Day, F. R., Fall, T., Ferreira, T., Gustafsson, S., Locke, A. E., Mathieson, I., & 31 othersScherag, A., Vedantam, S., Wood, A. R., Liang, L., Steinthorsdottir, V., Thorleifsson, G., Dermitzakis, E. T., Dimas, A. S., Karpe, F., Min, J. L., Nicholson, G., Clegg, D. J., Person, T., Krohn, J. P., Bauer, S., Buechler, C., Eisinger, K., Bonnefond, A., Froguel, P., Hottenga, J-J., Prokopenko, I., Waite, L. L., Harris, T. B., Campbell, H., Wilson, J. F., Hayward, C., Rudan, I., Bolton, J. L., Fowkes, G., Fraser, R. M. & Price, J. F., Jun 2013, In: PLoS Genetics. 9, 6, 19 p., e1003500.

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  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W., & 302 othersWood, A. R., Workalemahu, T., Hu, Y-J., Lee, S. H., Liang, L., Lin, D-Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., den Heijer, M., Eklund, N., Fischer, K., Goel, A., Hottenga, J-J., Huffman, J. E., Jarick, I., Johansson, A., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Collins, F. S., Connell, J. M., Cookson, W. O., de Faire, U., de Vegt, F., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A-L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J-O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K-T., Kivimäki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M-L., Lorentzon, M., Madden, P. A., Magnusson, P. K., Manunta, P., Marek, D., März, W., Mateo Leach, I., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N. A., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S-Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stančáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D-A., Tremoli, E., Van der Klauw, M. M., van Meurs, J. B. J., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C. M., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M-R., Jöckel, K-H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H-E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe, F., Moffatt, M. F., Mohlke, K. L., O'Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., van Duijn, C. M., Visscher, P. M., Di Blasio, A. M., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E., Loos, R. J. F. & Ingelsson, E., May 2013, In: Nature Genetics. 45, 5, p. 501-512 12 p.

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  • Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile

    Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kolcic, I., & 20 othersHansen, T., Gasperikova, D., Tjora, E., Strachan, M. W. J., Nielsen, T., Stanik, J., Klimes, I., Pedersen, O. B., Njølstad, P. R., Wild, S. H., Gyllensten, U., Gornik, O., Wilson, J. F., Hastie, N. D., Campbell, H., McCarthy, M. I., Rudd, P. M., Owen, K. R., Lauc, G. & Wright, A. F., Apr 2013, In: Diabetes . 62, 4, p. 1329-1337

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  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

    CREAM, Diabet Control Complications Trial, WTCCC2, Fuchs' Genetics Multi-Ctr Study Gr, Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Hoehn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., & 34 othersSt Pourcain, B., Simpson, C. L., Makela, K-M., Lehtimaki, T., Kahonen, M., Paterson, A. D., Hosseini, S. M., Wong, H. S., Xu, L., Jonas, J. B., Parssinen, O., Wedenoja, J., Yip, S. P., Ho, D. W. H., Pang, C. P., Chen, L. J., Burdon, K. P., Craig, J. E., Klein, B. E. K., Klein, R., Haller, T., Metspalu, A., Khor, C-C., Tai, E-S., Aung, T., Vithana, E., Tay, W-T., Barathi, V. A., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F., Fleck, B. & Vitart, V., Mar 2013, In: Nature Genetics. 45, 3, p. 314-318 5 p.

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  • Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study

    Demirkan, A., Isaacs, A., Ugocsai, P., Liebisch, G., Struchalin, M., Rudan, I., Wilson, J. F., Pramstaller, P. P., Gyllensten, U., Campbell, H., Schmitz, G., Oostra, B. A. & van Duijn, C. M., Mar 2013, In: Journal of Psychiatric Research. 47, 3, p. 357-362 6 p.

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  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

    LifeLines Cohort Study, Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, R. P. S., Brown, M. J., & 31 othersGaffo, A. L., Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., van der Harst, P., Li, X., Kleber, M. E., Wild, S. H., Tenesa, A., Navarro, P., Hastie, N., Davies, G., Gow, A. J., Wilson, J. F., Farrington, S. M., Theodoratou, E., Polasek, O., Campbell, H., Rudan, I., Deary, I. J., Wright, A. F. & Dunlop, M. G., Feb 2013, In: Nature Genetics. 45, 2, p. 145-154 10 p.

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  • Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

    NEIGHBOR Consortium, Lu, Y., Vitart, V., Burdon, K. P., Khor, C. C., Bykhovskaya, Y., Mirshahi, A., Hewitt, A. W., Koehn, D., Hysi, P. G., Ramdas, W. D., Zeller, T., Vithana, E. N., Cornes, B. K., Tay, W-T., Tai, E. S., Cheng, C-Y., Liu, J., Foo, J-N., Saw, S. M., & 31 othersThorleifsson, G., Stefansson, K., Dimasi, D. P., Mills, R. A., Mountain, J., Ang, W., Hoehn, R., Verhoeven, V. J. M., Grus, F., Wolfs, R., Castagne, R., Lackner, K. J., Springelkamp, H., Yang, J., Jonasson, F., Leung, D. Y. L., Chen, L. J., Tham, C. C. Y., Rudan, I., Vatavuk, Z., Hayward, C., Gibson, J., Cree, A. J., Macleod, A., Ennis, S., Polasek, O., Campbell, H., Wilson, J. F., Viswanathan, A. C., Fleck, B. & Wright, A. F., Feb 2013, In: Nature Genetics. 45, 2, p. 155-163 9 p.

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  • Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

    Lauc, G., Huffman, J. E., Pučić, M., Zgaga, L., Adamczyk, B., Mužinić, A., Novokmet, M., Polsek, O., Gornik, O., Krištić, J., Keser, T., Vitart, V., Scheijen, B., Uh, H-W., Molokhia, M., Patrick, A. L., McKeigue, P., Kolčić, I., Lukić, I. K., Swann, O., & 19 othersvan Leeuwen, F. N., Ruhaak, L. R., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Deelder, A. M., Zeng, Q., Wang, W., Hastie, N. D., Gyllensten, U., Wilson, J. F., Wuhrer, M., Wright, A. F., Rudd, P. M., Hayward, C., Aulchenko, Y., Campbell, H. & Rudan, I., 31 Jan 2013, In: PLoS Genetics. 9, 1, e1003225.

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  • A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

    Allebrandt, K. V., Amin, N., Mueller-Myhsok, B., Esko, T., Teder-Laving, M., Azevedo, R. V. D. M., Hayward, C., van Mill, J., Vogelzangs, N., Green, E. W., Melville, S. A., Lichtner, P., Wichmann, H-E., Oostra, B. A., Janssens, A. C. J. W., Campbell, H., Wilson, J. F., Hicks, A. A., Pramstaller, P. P., Dogas, Z., & 8 othersRudan, I., Merrow, M., Penninx, B., Kyriacou, C. P., Metspalu, A., van Duijn, C. M., Meitinger, T. & Roenneberg, T., Jan 2013, In: Molecular Psychiatry. 18, 1, p. 122-132 11 p.

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  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

    Early Growth Genetics EGG, MAGIC, Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimaki, T., Kreiner-Moller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., & 31 othersPfab, T., Barton, S. J., Shields, B. M., Kerkhof, M., van Leeuwen, E. M., Fulford, A. J., Kutalik, Z., Zhao, J. H., den Hoed, M., Mahajan, A., Lindi, V., Goh, L-K., Hottenga, J-J., Wu, Y., Raitakari, O. T., Harder, M. N., Meirhaeghe, A., Ntalla, I., Salem, R. M., Jameson, K. A., Zhou, K., Monies, D. M., Lagou, V., Kirin, M., Heikkinen, J., Adair, L. S., Alkuraya, F. S., Al-Odaib, A., Amouyel, P., Andersson, E. A. & Wilson, J. F., Jan 2013, In: Nature Genetics. 45, 1, p. 76-U115 10 p.

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  • 2012

    Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

    CARDIoGRAM Consortium, Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., & 31 othersLiu, C-T., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M. F., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Tönjes, A., Dehghan, A., Lambert, J-C., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Zgaga, L., Wild, S. H., Wright, A. F., Campbell, H., Hastie, N., Vitart, V., Colhoun, H., Rudan, I., Wilson, J. F. & Hayward, C., 15 Dec 2012, In: Human Molecular Genetics. 21, 24, p. 5329-5343 15 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide meta-analysis of common variant differences between men and women

    Wellcome Trust Case Control Consortium, Boraska, V., Jerončić, A., Colonna, V., Southam, L., Nyholt, D. R., Rayner, N. W., Perry, J. R. B., Toniolo, D., Albrecht, E., Ang, W., Bandinelli, S., Barbalic, M., Barroso, I., Beckmann, J. S., Biffar, R., Boomsma, D., Campbell, H., Corre, T., Erdmann, J., & 31 othersEsko, T., Fischer, K., Franceschini, N., Frayling, T. M., Girotto, G., Gonzalez, J. R., Harris, T. B., Heath, A. C., Heid, I. M., Hoffmann, W., Hofman, A., Horikoshi, M., Zhao, J. H., Jackson, A. U., Hottenga, J-J., Jula, A., Kähönen, M., Khaw, K-T., Kiemeney, L. A., Klopp, N., Kutalik, Z., Lagou, V., Launer, L. J., Lehtimäki, T., Lemire, M., Pirastu, N., Wright, A. F., Zgaga, L., Hayward, C., Wilson, J. F. & Rudan, I., Nov 2012, In: Human Molecular Genetics. 21, 21, p. 4805-15 11 p.

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  • Localising Loci underlying Complex Trait Variation Using Regional Genomic Relationship Mapping

    Nagamine, Y., Pong-Wong, R., Navarro, P., Vitart, V., Hayward, C., Rudan, I., Campbell, H., Wilson, J., Wild, S., Hicks, A. A., Pramstaller, P. P., Hastie, N., Wright, A. F. & Haley, C. S., Oct 2012, In: PLoS ONE. 7, 10, 12 p., e46501.

    Research output: Contribution to journalArticlepeer-review

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  • Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene

    EUROSPAN Consortium, Johansson, A., Marroni, F., Hayward, C., Franklin, C. S., Kirichenko, A. V., Jonasson, I., Hicks, A. A., Vitart, V., Isaacs, A., Axenovich, T., Campbell, S., Floyd, J., Hastie, N., Knott, S., Lauc, G., Pichler, I., Rotim, K., Wild, S. H., Zorkoltseva, I. V., & 10 othersWilson, J. F., Rudan, I., Campbell, H., Pattaro, C., Pramstaller, P., Oostra, B. A., Wright, A. F., van Duijn, C. M., Aulchenko, Y. S. & Gyllensten, U., 6 Sept 2012, In: Obesity. 18, 4, p. 803-8 6 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association uncovers shared genetic effects among personality traits and mood states

    Luciano, M., Huffman, J. E., Arias-Vásquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G., Zgaga, L., Janzing, J., Ke, X., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J-J., Konte, B., & 24 othersStarr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N. D., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 1 Sept 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

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  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    DIAbet Genetics Replication, Asian Genetic Epidemiology, Genetic Invest ANthropometric, Meta-Anal Glucose Insulin-Related, S Asian Type 2 Diabet SAT2D, Wellcome Trust Case Control, Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segre, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H. M., Dina, C., Esko, T., Fraser, R. M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C., & 31 othersLuan, J., Lindgren, C. M., Mueller-Nurasyid, M., Pechlivanis, S., Rayner, N. W., Scott, L. J., Wiltshire, S., Yengo, L., Kinnunen, L., Rossin, E. J., Raychaudhuri, S., Johnson, A. D., Dimas, A. S., Loos, R. J. F., Vedantam, S., Chen, H., Florez, J. C., Fox, C., Liu, C-T., Rybin, D., Couper, D. J., Kao, W. H. L., Li, M., Cornelis, M. C., Kraft, P., Sun, Q., van Dam, R. M., Campbell, H., Price, J. F., Wilson, J. F. & Morris, A., Sept 2012, In: Nature Genetics. 44, 9, p. 981-90 10 p.

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  • Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

    Verhoeven, V. J. M., Hysi, P. G., Saw, S-M., Vitart, V., Mirshahi, A., Guggenheim, J. A., Cotch, M. F., Yamashiro, K., Baird, P. N., Mackey, D. A., Wojciechowski, R., Ikram, M. K., Hewitt, A. W., Duggal, P., Janmahasatian, S., Khor, C-C., Fan, Q., Zhou, X., Young, T. L., Tai, E-S., & 75 othersGoh, L-K., Li, Y-J., Aung, T., Vithana, E., Teo, Y-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A. F., Polasek, O., Campbell, H., Wilson, J. F., Fleck, B. W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St Pourcain, B., Lu, Y., Rahi, J. S., Cumberland, P. M., Bhattacharya, S., Simpson, C. L., Atwood, L. D., Li, X., Raffel, L. J., Murgia, F., Portas, L., Despriet, D. D. G., van Koolwijk, L. M. E., Wolfram, C., Lackner, K. J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B. E., Meitinger, T., Spector, T. D., Oostra, B. A., Smith, A. V., de Jong, P. T. V. M., Hofman, A., Amin, N., Karssen, L. C., Rivadeneira, F., Vingerling, J. R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A. G., Williams, C., Zeller, T., Castagné, R., Oexle, K., van Duijn, C. M., Iyengar, S. K., Mitchell, P., Wang, J. J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J. E., Stambolian, D., Wong, T-Y., Hammond, C. J. & Klaver, C. C. W., Sept 2012, In: Human Genetics. 131, 9, p. 1467-80 14 p.

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  • Uncovering Networks from Genome-Wide Association Studies via Circular Genomic Permutation

    Cabrera, C. P., Navarro, P., Huffman, J. E., Wright, A. F., Hayward, C., Campbell, H., Wilson, J. F., Rudan, I., Hastie, N. D., Vitart, V. & Haley, C. S., Sept 2012, In: G3: Genes | Genomes | Genetics. 2, 9, p. 1067-75 9 p.

    Research output: Contribution to journalArticlepeer-review

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  • A new prevalence study of multiple sclerosis in Orkney, Shetland and Aberdeen city

    Visser, E. M., Wilde, K., Wilson, J. F., Yong, K. K. & Counsell, C. E., Jul 2012, In: Journal of Neurology, Neurosurgery & Psychiatry. 83, 7, p. 719-724 6 p.

    Research output: Contribution to journalArticlepeer-review

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

    MUTHER Consortium, DIAGRAM Consortium, Manning, A. K., Hivert, M-F., Scott, R. A., Grimsby, J. L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C-T., Bielak, L. F., Prokopenko, I., Amin, N., Barnes, D., Cadby, G., Hottenga, J-J., Ingelsson, E., Jackson, A. U., Johnson, T., Kanoni, S., Ladenvall, C., & 31 othersLagou, V., Lahti, J., Lecoeur, C., Liu, Y., Martinez-Larrad, M. T., Montasser, M. E., Navarro, P., Perry, J. R. B., Rasmussen-Torvik, L. J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R. J., Tanaka, T., van Duijn, C. M., An, P., de Andrade, M., Andrews, J. S., Aspelund, T., Atalay, M., Aulchenko, Y., Balkau, B., Bandinelli, S., Campbell, H., Hayward, C., Rudan, I., Vitart, V., Wild, S. H., Wilson, J. F., Wright, A. F. & Zgaga, L., Jun 2012, In: Nature Genetics. 44, 6, p. 659-U81 13 p.

    Research output: Contribution to journalArticlepeer-review

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  • Genetic adaptation of fatty-acid metabolism: A human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

    Ameur, A., Enroth, S., Johansson, A., Zaboli, G., Igl, W., Johansson, A. C. V., Rivas, M. A., Daly, M. J., Schmitz, G., Hicks, A. A., Meitinger, T., Feuk, L., van Duijn, C., Oostra, B., Pramstaller, P. P., Rudan, I., Wright, A. F., Wilson, J. F., Campbell, H. & Gyllensten, U., 4 May 2012, In: American Journal of Human Genetics. 90, 5, p. 809-820 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Common variants at 6q22 and 17q21 are associated with intracranial volume

    Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genomic Ep, Ikram, M. A., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., & 31 othersRivadeneira, F., Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G. & Wilson, J. F., May 2012, In: Nature Genetics. 44, 5, p. 539-+ 7 p.

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  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

    Estrada, K., Styrkarsdottir, U., Evangelou, E., Hsu, Y-H., Duncan, E. L., Ntzani, E. E., Oei, L., Albagha, O. M. E., Amin, N., Kemp, J. P., Koller, D. L., Li, G., Liu, C-T., Minster, R. L., Moayyeri, A., Vandenput, L., Willner, D., Xiao, S-M., Yerges-Armstrong, L. M., Zheng, H-F., & 161 othersAlonso, N., Eriksson, J., Kammerer, C. M., Kaptoge, S. K., Leo, P. J., Thorleifsson, G., Wilson, S. G., Wilson, J. F., Aalto, V., Alen, M., Aragaki, A. K., Aspelund, T., Center, J. R., Dailiana, Z., Duggan, D. J., Garcia, M., Garcia-Giralt, N., Giroux, S., Hallmans, G., Hocking, L. J., Husted, L. B., Jameson, K. A., Khusainova, R., Kim, G. S., Kooperberg, C., Koromila, T., Kruk, M., Laaksonen, M., Lacroix, A. Z., Lee, S. H., Leung, P. C., Lewis, J. R., Masi, L., Mencej-Bedrac, S., Nguyen, T. V., Nogues, X., Patel, M. S., Prezelj, J., Rose, L. M., Scollen, S., Siggeirsdottir, K., Smith, A. V., Svensson, O., Trompet, S., Trummer, O., van Schoor, N. M., Woo, J., Zhu, K., Balcells, S., Brandi, M. L., Buckley, B. M., Cheng, S., Christiansen, C., Cooper, C., Dedoussis, G., Ford, I., Frost, M., Goltzman, D., González-Macías, J., Kähönen, M., Karlsson, M., Khusnutdinova, E., Koh, J-M., Kollia, P., Langdahl, B. L., Leslie, W. D., Lips, P., Ljunggren, Ö., Lorenc, R. S., Marc, J., Mellström, D., Obermayer-Pietsch, B., Olmos, J. M., Pettersson-Kymmer, U., Reid, D. M., Riancho, J. A., Ridker, P. M., Rousseau, F., Slagboom, P. E., Tang, N. L. S., Urreizti, R., Van Hul, W., Viikari, J., Zarrabeitia, M. T., Aulchenko, Y. S., Castano-Betancourt, M., Grundberg, E., Herrera, L., Ingvarsson, T., Johannsdottir, H., Kwan, T., Li, R., Luben, R., Medina-Gómez, C., Palsson, S. T., Reppe, S., Rotter, J. I., Sigurdsson, G., van Meurs, J. B. J., Verlaan, D., Williams, F. M. K., Wood, A., Zhou, Y., Gautvik, K. M., Pastinen, T., Raychaudhuri, S., Cauley, J. A., Chasman, D. I., Clark, G. R., Cummings, S. R., Danoy, P., Dennison, E. M., Eastell, R., Eisman, J. A., Gudnason, V., Hofman, A., Jackson, R. D., Jones, G., Jukema, J. W., Khaw, K-T., Lehtimäki, T., Liu, Y., Lorentzon, M., McCloskey, E., Mitchell, B. D., Nandakumar, K., Nicholson, G. C., Oostra, B. A., Peacock, M., Pols, H. A. P., Prince, R. L., Raitakari, O., Reid, I. R., Robbins, J., Sambrook, P. N., Sham, P. C., Shuldiner, A. R., Tylavsky, F. A., van Duijn, C. M., Wareham, N. J., Cupples, L. A., Econs, M. J., Evans, D. M., Harris, T. B., Kung, A. W. C., Psaty, B. M., Reeve, J., Spector, T. D., Streeten, E. A., Zillikens, M. C., Thorsteinsdottir, U., Ohlsson, C., Karasik, D., Richards, J. B., Brown, M. A., Stefansson, K., Uitterlinden, A. G., Ralston, S. H., Ioannidis, J. P. A., Kiel, D. P. & Rivadeneira, F., May 2012, In: Nature Genetics. 44, 5, p. 491-501 11 p.

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  • Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases

    GIANT Consortium, DIAGRAM Consortium, MAGIC, Perry, J. R. B., Voight, B. F., Yengo, L., Amin, N., Dupuis, J., Ganser, M., Grallert, H., Navarro, P., Li, M., Qi, L., Steinthorsdottir, V., Scott, R. A., Almgren, P., Arking, D. E., Aulchenko, Y., Balkau, B., Benediktsson, R., Bergman, R. N., Boerwinkle, E., & 31 othersBonnycastle, L., Burtt, N. P., Campbell, H., Charpentier, G., Collins, F. S., Gieger, C., Green, T., Hadjadj, S., Hattersley, A. T., Herder, C., Hofman, A., Johnson, A. D., Kottgen, A., Kraft, P., Labrune, Y., Langenberg, C., Manning, A. K., Mohlke, K. L., Morris, A. P., Oostra, B., Pankow, J., Petersen, A-K., Pramstaller, P. P., Prokopenko, I., Rathmann, W., Rayner, W., Roden, M., Rudan, I., Wright, A. F., Wilson, J. F. & Morris, A., May 2012, In: PLoS Genetics. 8, 5, p. 1-14 14 p., e1002741.

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  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

    Stolk, L., Zillikens, M. C., Uitterlinden, A. G., Visser, J. A., Hofman, A., Van Duijn, C. M., Perry, J. R. B., Melzer, D., Murray, A., Chasman, D. I., Paré, G., Buring, J. E., Crisponi, L., Ridker, P. M., He, C., Mangino, M., Zhai, G., Burri, A., Soranzo, N., Spector, T. D., & 159 othersSulem, P., Gudbjartsson, D. F., Stacey, S. N., Styrkarsdottir, U., Stefansson, K., Thorsteinsdottir, U., Barbalic, M., Boerwinkle, E., Broer, L., Van Wingerden, S., Janssens, A. C. J. W., Byrne, E. M., Martin, N. G., Medland, S. E., Nyholt, D. R., Montgomery, G. W., Ernst, F., Esko, T., Fischer, K., Haller, T., Hass, M., Salumets, A., Metspalu, A., Völzke, H., Franceschini, N., Hottenga, J-J., De Geus, E. J. C., Vink, J. M., Willemsen, G., Boomsma, D. I., Kraft, P., Chen, C., Hankinson, S. E., Hu, F. B., Hunter, D. J., McArdle, P. F., Yerges-Armstrong, L. M., Streeten, E. A., Porcu, E., Ferreli, L., Lai, S., Marongiu, M., Sanna, S., Uda, M., Shin, S-Y., Deloukas, P., Palotie, A., Stirrups, K., Smith, A. V., Aspelund, T., Eiriksdottir, G., Emilsson, V., Gudnason, V., Tryggvadottir, L., Zhuang, W. V., Lunetta, K. L., Albrecht, E., Gieger, C., Alizadeh, B. Z., Snieder, H., Stolk, R. P., Bandinelli, S., Lauc, L. B., Beckmann, J. S., Kutalik, Z., Boban, M., Kolcic, I., Polasek, O., Rudan, I., Zemunik, T., Broekmans, F. J., Fauser, B. C. J. M., Voorhuis, M., Campbell, H., Wilson, J. F., Zgaga, L., Chanock, S. J., Cornelis, M. C., Van Dam, R. M., Corre, T., Masciullo, C., Pistis, G., Sala, C., Toniolo, D., Coviello, A. D., Glazer, N., Murabito, J. M., Johnson, A. D., Karasik, D., Kiel, D. P., D'Adamo, P., Gasparini, P., Ulivi, S., Davies, G., Deary, I. J., Lopez, L. M., De Faire, U., Starr, J. M., Visscher, P. M., Dedoussis, G. V. Z., Stathopoulou, M. G., Ebrahim, S., Eriksson, J. G., Demerath, E. W., Ferrucci, L., Folsom, A. R., Garcia, M. E., Harris, T. B., Launer, L. J., Grobbee, D. E., Onland-Moret, N. C., Peeters, P. H. M., Van Der Schouw, Y. T., Van Gils, C. H., Hall, P., Ingelsson, E., Magnusson, P. K. E., Pedersen, N. L., Rehnberg, E., Hayward, C., Navarro, P., Tenesa, A., Wright, A. F., Heath, A. C., Kardia, S. L. R., Smith, J. A., Keyzer, J., Lahti, J., R Currency Signikkönen, K., Laisk, T., Laven, J. S. E., Louwers, Y. V., Lawlor, D. A., Liu, J., Klaric, I. M., McKnight, B., Arnold, A. M., Mooser, V., Newman, A. B., Widen, E., Parker, A. N., Tsui, K., Plump, A. S., Pop, V. J. M., Psaty, B. M., Rotter, J. I., Scuteri, A., Singleton, A., Wolffenbuttel, B. H. R., Sun, Y. V., Thorand, B., Van Nierop, P., Waeber, G., Wallaschofski, H., Wichmann, H. E., Wijnands-Van Gent, C. J. M., Zygmunt, M., Oostra, B. A. & Schlessinger, D., 1 Mar 2012, In: Nature Genetics. 44, 3, p. 260-268 9 p.

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  • Association of medication with the human plasma N-glycome

    Saldova, R., Huffman, J. E., Adamczyk, B., Mužinić, A., Kattla, J. J., Pučić, M., Novokmet, M., Abrahams, J. L., Hayward, C., Rudan, I., Wild, S. H., Wright, A. F., Polašek, O., Lauc, G., Campbell, H., Wilson, J. F. & Rudd, P. M., 18 Jan 2012, In: Journal Of Proteome Research. 11, 3, p. 1821-31 11 p.

    Research output: Contribution to journalArticlepeer-review

  • A genome-wide association search for type 2 diabetes genes in African Americans

    DIAGRAM Consortium, Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., & 31 othersRotimi, C. N., Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Navarro, P., Rudan, I., Campbell, H., Wilson, J. F., Hayward, C., Vitart, V., Wild, S. H. & Wright, A. F., 2012, In: PLoS ONE. 7, 1, p. 1-14 14 p., e29202.

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  • Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

    Murabito, J. M., White, C. C., Kavousi, M., Sun, Y. V., Feitosa, M. F., Nambi, V., Lamina, C., Schillert, A., Coassin, S., Bis, J. C., Broer, L., Crawford, D. C., Franceschini, N., Frikke-Schmidt, R., Haun, M., Holewijn, S., Huffman, J. E., Hwang, S-J., Kiechl, S., Kollerits, B., & 109 othersMontasser, M. E., Nolte, I. M., Rudock, M. E., Senft, A., Teumer, A., van der Harst, P., Vitart, V., Waite, L. L., Wood, A. R., Wassel, C. L., Absher, D. M., Allison, M. A., Amin, N., Arnold, A., Asselbergs, F. W., Aulchenko, Y., Bandinelli, S., Barbalic, M., Boban, M., Brown-Gentry, K., Couper, D. J., Criqui, M. H., Dehghan, A., den Heijer, M., Dieplinger, B., Ding, J., Dörr, M., Espinola-Klein, C., Felix, S. B., Ferrucci, L., Folsom, A. R., Fraedrich, G., Gibson, Q., Goodloe, R., Gunjaca, G., Haltmayer, M., Heiss, G., Hofman, A., Kieback, A., Kiemeney, L. A., Kolcic, I., Kullo, I. J., Kritchevsky, S. B., Lackner, K. J., Li, X., Lieb, W., Lohman, K., Meisinger, C., Melzer, D., Mohler, E. R., Mudnic, I., Mueller, T., Navis, G., Oberhollenzer, F., Olin, J. W., O'Connell, J., O'Donnell, C. J., Palmas, W., Penninx, B. W., Petersmann, A., Polasek, O., Psaty, B. M., Rantner, B., Rice, K., Rivadeneira, F., Rotter, J. I., Seldenrijk, A., Stadler, M., Summerer, M., Tanaka, T., Tybjaerg-Hansen, A., Uitterlinden, A. G., van Gilst, W. H., Vermeulen, S. H., Wild, S. H., Wild, P. S., Willeit, J., Zeller, T., Zemunik, T., Zgaga, L., Assimes, T. L., Blankenberg, S., Boerwinkle, E., Campbell, H., Cooke, J. P., de Graaf, J., Herrington, D., Kardia, S. L. R., Mitchell, B. D., Murray, A., Münzel, T., Newman, A. B., Oostra, B. A., Rudan, I., Shuldiner, A. R., Snieder, H., van Duijn, C. M., Völker, U., Wright, A. F., Wichmann, H-E., Wilson, J. F., Witteman, J. C. M., Liu, Y., Hayward, C., Borecki, I. B., Ziegler, A., North, K. E., Cupples, L. A. & Kronenberg, F., 2012, In: Circulation: Cardiovascular Genetics. 5, 1, p. 100-12 13 p.

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  • Discovery and fine mapping of serum protein loci through transethnic meta-analysis

    LifeLines Cohort Study, Franceschini, N., van Rooij, F. J. A., Prins, B. P., Feitosa, M. F., Karakas, M., Eckfeldt, J. H., Folsom, A. R., Kopp, J., Vaez, A., Andrews, J. S., Baumert, J., Boraska, V., Broer, L., Hayward, C., Ngwa, J. S., Okada, Y., Polasek, O., Westra, H-J., Wang, Y. A., & 31 othersDel Greco M, F., Glazer, N. L., Kapur, K., Kema, I. P., Lopez, L. M., Schillert, A., Smith, A. V., Winkler, C. A., Zgaga, L., Bandinelli, S., Bergmann, S., Boban, M., Bochud, M., Chen, Y. D., Davies, G., Dehghan, A., Ding, J., Doering, A., Durda, J. P., Ferrucci, L., Franco, O. H., Franke, L., Gunjaca, G., Hofman, A., Starr, J. M., Vitart, V., Campbell, H., Deary, I. J., Rudan, I., Wilson, J. F. & Wright, A. F., 2012, In: American Journal of Human Genetics. 91, 4, p. 744-53 10 p.

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  • Evidence of Inbreeding Depression on Human Height

    on behalf of the ROHgen Consortium, McQuillan, R., Eklund, N., Pirastu, N., Kuningas, M., McEvoy, B. P., Esko, T., Corre, T., Davies, G., Kaakinen, M., Lyytikäinen, L-P., Kristiansson, K., Havulinna, A. S., Gögele, M., Vitart, V., Tenesa, A., Aulchenko, Y., Hayward, C., Johansson, A., Boban, M., & 31 othersUlivi, S., Robino, A., Boraska, V., Igl, W., Wild, S. H., Zgaga, L., Amin, N., Theodoratou, E., Polašek, O., Girotto, G., Lopez, L. M., Sala, C., Lahti, J., Laatikainen, T., Prokopenko, I., Kals, M., Viikari, J., Yang, J., Pouta, A., Estrada, K., Starr, J. M., Farrington, S. M., Campbell, H., Porteous, D., Hastie, N. D., Wright, A. F., Dunlop, M., Rudan, I., Deary, I. J., Visscher, P. M. & Wilson, J. F., 2012, In: PLoS Genetics. 8, 7, e1002655.

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  • FTO genotype is associated with phenotypic variability of body mass index

    Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E., & 152 othersWang, S. R., Palmer, C., Esko, T., Fischer, K., Zhao, J. H., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, J., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., Van Vliet-Ostaptchouk, J. V., Hottenga, J-J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Junttila, M. J., Grönberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Khaw, K. T., van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J-C., Huikuri, H. V., Cupples, L. A., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., Van der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, J. D., Ripatti, S., Jarvelin, M-R., de Geus, E. J. C., Boomsma, D. I., Penninx, B., Wilson, J. F., Campbell, H., Chanock, S. J., van der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Zillikens, M. C., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Tönjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, D. R., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., 2012, In: Nature. 490, 7419, p. 267-272 6 p.

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  • Genome-wide analysis of epistasis in body mass index using multiple human populations

    Wei, W., Hemani, G., Gyenesei, A., Vitart, V., Navarro, P., Hayward, C., Cabrera-Cardenas, C., Huffman, J. E., Knott, S. A., Hicks, A. A., Rudan, I., Pramstaller, P. P., Wild, S. H., Wilson, J. F., Campbell, H., Hastie, N. D., Wright, A. F. & Haley, C. S., 2012, In: European Journal of Human Genetics. 20, 8, p. 857-62 6 p.

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  • Genome-wide association and functional follow-up reveals new loci for kidney function

    CARDIoGRAM Consortium, Pattaro, C., Köttgen, A., Teumer, A., Garnaas, M., Böger, C. A., Fuchsberger, C., Olden, M., Chen, M-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., & 31 othersLiu, C-T., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Chouraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Wild, S. H., Wright, A. F., Campbell, H., Hastie, N., Vitart, V., Colhoun, H., Rudan, I., Wilson, J. F. & Hayward, C., 2012, In: PLoS Genetics. 8, 3, p. e1002584

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  • Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

    DIAGRAM Consortium, Demirkan, A., van Duijn, C. M., Ugocsai, P., Isaacs, A., Pramstaller, P. P., Liebisch, G., Wilson, J. F., Johansson, Å., Rudan, I., Aulchenko, Y. S., Kirichenko, A. V., Janssens, A. C. J. W., Jansen, R. C., Gnewuch, C., Domingues, F. S., Pattaro, C., Wild, S. H., Jonasson, I., Polasek, O., & 31 othersZorkoltseva, I. V., Hofman, A., Karssen, L. C., Struchalin, M., Floyd, J., Igl, W., Biloglav, Z., Broer, L., Pfeufer, A., Pichler, I., Campbell, S., Zaboli, G., Kolcic, I., Rivadeneira, F., Huffman, J., Hastie, N. D., Uitterlinden, A., Franke, L., Franklin, C. S., Vitart, V., Nelson, C. P., Preuss, M., Bis, J. C., O'Donnell, C. J., Franceschini, N., Witteman, J. C. M., Axenovich, T., Oostra, B. A., Hayward, C., Wright, A. F. & Campbell, H., 2012, In: PLoS Genetics. 8, 2, p. e1002490

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  • Genome-wide homozygosity and multiple sclerosis in Orkney and Shetland Islanders

    McWhirter, R. E., McQuillan, R., Visser, E., Counsell, C. & Wilson, J. F., 2012, In: European Journal of Human Genetics. 20, 2, p. 198-202 5 p.

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  • Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

    IL6R Genetics Consortium Emerging Risk Factors Collaboration, Sarwar, N., Butterworth, A. S., Freitag, D. F., Gregson, J., Willeit, P., Gorman, D. N., Gao, P., Saleheen, D., Rendon, A., Nelson, C. P., Braund, P. S., Hall, A. S., Chasman, D. I., Tybjærg-Hansen, A., Chambers, J. C., Benjamin, E. J., Franks, P. W., Clarke, R., Wilde, A. A. M., & 31 othersTrip, M. D., Steri, M., Witteman, J. C. M., Qi, L., van der Schoot, C. E., de Faire, U., Erdmann, J., Stringham, H. M., Koenig, W., Rader, D. J., Melzer, D., Reich, D., Psaty, B. M., Kleber, M. E., Panagiotakos, D. B., Willeit, J., Wennberg, P., Woodward, M., Adamovic, S., Rimm, E. B., Meade, T. W., Gillum, R. F., Shaffer, J. A., Hofman, A., Onat, A., Sundström, J., Wassertheil-Smoller, S., Mellström, D., Gallacher, J., Cushman, M. & Wilson, J. F., 2012, In: The Lancet. 379, 9822, p. 1205-13 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, J., Mägi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., & 31 othersJohnson, T., Mahajan, A., Verweij, N., Thorleifsson, G., Hottenga, J-J., Shah, S., Smith, A. V., Sennblad, B., Gieger, C., Salo, P., Perola, M., Timpson, N. J., Evans, D. M., Pourcain, B. S., Wu, Y., Andrews, J. S., Hui, J., Bielak, L. F., Navarro, P., Vitart, V., Hayward, C., Fraser, R. M., Bolton, J. L., Wild, S. H., Hastie, N. D., Rudan, I., Campbell, H., Wilson, J. F., Wright, A. F., Price, J. F. & Morris, A., 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.

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  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

    DIAGRAM+ Consortium, Dastani, Z., Hivert, M-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., & 31 othersKanoni, S., Pankow, J. S., Uh, H-W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C-T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Wilson, J. G., Navarro, P., Morris, A., Rudan, I., Campbell, H., Wilson, J. F., Hayward, C., Sharp, S. J., Vitart, V., Wild, S. H., Wright, A. F., Thompson, J. R. & Hastie, N. D., 2012, In: PLoS Genetics. 8, 3, p. e1002607

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  • Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits

    EUROSPAN Consortium, Zaboli, G., Ameur, A., Igl, W., Johansson, Å., Hayward, C., Vitart, V., Campbell, S., Zgaga, L., Polasek, O., Schmitz, G., van Duijn, C., Oostra, B., Pramstaller, P., Hicks, A., Meitinger, T., Rudan, I., Wright, A., Wilson, J. F., Campbell, H., & 1 othersGyllensten, U., 2012, In: European Journal of Human Genetics. 20, 1, p. 77-83 7 p.

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  • The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269

    Busby, G. B. J., Brisighelli, F., Sánchez-Diz, P., Ramos-Luis, E., Martinez-Cadenas, C., Thomas, M. G., Bradley, D. G., Gusmão, L., Winney, B., Bodmer, W., Vennemann, M., Coia, V., Scarnicci, F., Tofanelli, S., Vona, G., Ploski, R., Vecchiotti, C., Zemunik, T., Rudan, I., Karachanak, S., & 8 othersToncheva, D., Anagnostou, P., Ferri, G., Rapone, C., Hervig, T., Moen, T., Wilson, J. F. & Capelli, C., 2012, In: Proceedings of the Royal Society B-Biological Sciences. 279, 1730, p. 884-92 9 p.

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