Personal profile
Current Research Interests
The equine cardiovascular system and its relationship to endocrinological disorders such as equine metabolic syndrome and pituitary pars intermedia dysfunction.
Administrative Roles
Equine Medicine
Biography
RCVS and European Specialist in Equine Medicine (Internal Medicine), Senior Lecturer in Equine Internal Medicine, Director of Equine Clinical Services
Following graduation from the RVC in 1996, John spent 4 years in mixed and then predominantly equine practice before being appointed the RCVS Clarke and Sparrow Resident in Equine Studies at the ‘Dick’ Vet in 2000, where he has remained ever since.
He has gained his Certificate in Equine Internal Medicine, MSc by research and a PhD investigating the pharmacology and physiology of digital laminar microvasculature.
He was awarded the European Diploma in Equine Internal Medicine in 2007 and has gained RCVS and European specialist status in equine internal medicine.
John is currently a senior clinician in the equine hospital. His clinical and research interests include all aspects of internal medicine, but with particular emphasis on cardiovascular disease, metabolic and endocrine disease and the potential links between these disorders.
Education/Academic qualification
Doctor of Philosophy (PhD), Investigation of the Structure and Function of Equine Laminar Blood Vessels, Glasgow Caledonian University
Award Date: 1 Jan 2009
Master of Science, The Role of Oxifdative Stress and Microvascular Dysfunction in the Pathogenesis of Laminitis, University of Edinburgh
Award Date: 1 Jan 2004
Bachelors in Veterinary Medicine, Royal Veterinary College
Award Date: 1 Jan 1996
Bachelor of Science, University of Edinburgh
Award Date: 1 Jan 1992
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Collaborations and top research areas from the last five years
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Endothelin mediated contraction of equine laminar veins
Keen, J., Hillier, C., McGorum, B. & Nally, J. E., Jul 2008, In: Equine Veterinary Journal. 40, 5, p. 488-492 5 p.Research output: Contribution to journal › Article › peer-review
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Retrospective Evaluation of Episodic Collapse in the Horse in a Referred Population: 25 Cases (1995-2009)
Lyle, C. H., Turley, G., Blissitt, K. J., Pirie, R. S., Mayhew, I. G., McGorum, B. C. & Keen, J. A., 2010, In: Journal of Veterinary Internal Medicine. 24, 6, p. 1498-1502 5 p.Research output: Contribution to journal › Article › peer-review
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Short-term incubation of equine laminar veins with cortisol and insulin alters contractility in vitro: possible implications for the pathogenesis of equine laminitis
Keen, J. A., McGorum, B. C., Hillier, C. & Nally, J. E., Aug 2013, In: Journal of Veterinary Pharmacology and Therapeutics. 36, 4, p. 382-388 7 p.Research output: Contribution to journal › Article › peer-review
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Evaluation of equine laminar vein function: harvesting, dissection and the use of functional methods to distinguish between veins and arteries
Keen, J. A., Hillier, C., McGorum, B. C., Bunton, D. & Nally, J. E., 2008, In: Journal of Pharmacological and Toxicological Methods. 57, 2, p. 92-9 8 p.Research output: Contribution to journal › Article › peer-review
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Markers of hepathic insulin clearance and their association with steatosis in hyperinsulinaemic horses
Dosi, M., Scott, L., Payne, H., Poldy, J., Keen, J., McGorum, B., Malbon, A. & Morgan, R., 1 Jul 2025, In: Journal of Veterinary Internal Medicine. 39, 4, p. 1-9 9 p., e70143.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Preliminary study to test the feasibility of a novel minimally invasive, non-imaging, oesophageal Doppler ECG thermistor (ODET) probe to monitor cardiovascular function in anaesthetised horses.
Blissitt, K. (Principal Investigator), Keen, J. (Co-investigator) & Malbon, A. (Co-investigator)
Association of Veterinary Anaesthetists
1/07/25 → 30/04/26
Project: Research
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Interdependence of structure and function: using electroanatomic mapping and MRI to determine the tissue characteristics driving propagation in the equine heart
Keen, J. (Principal Investigator), Kershaw, L. (Co-investigator) & Williams, S. (Co-investigator)
The Hong Kong Jockey Club Equine Welfare Research Foundation Limited
1/12/24 → 30/11/25
Project: Research
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Vitamin D in equine adipose tissue
Keen, J. (Principal Investigator), Dosi, M. (Co-investigator) & Morgan, R. (Co-investigator)
1/01/23 → 31/12/23
Project: Research
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The role of corisol dysregulation in endocrinopathic laminitis
Keen, J. (Principal Investigator)
Biotechnology and Biological Sciences Research Council
1/03/12 → 29/02/16
Project: Research
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The role of corisol dysregulation in endocrinopathic laminitis: studentship ruth morgan
Keen, J. (Principal Investigator)
UK industry, commerce and public corporations
1/03/12 → 30/04/16
Project: Research
Press/Media
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Heart of the Matter: Grand National winner One for Arthur getting back on track
29/02/20
1 Media contribution
Press/Media: Project or Organisational News Item
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John Keen treats race horse 'Big River' for atrial fibrillation
29/11/17
1 item of Media coverage
Press/Media: Project or Organisational News Item
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Dr John Keen comments on causes of laminitis, a condition suffered by horses and ponies
15/06/13
1 item of Media coverage
Press/Media: Expert Comment