Julien Michel – Projects — University of Edinburgh Research Explorer

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Phone0131 650 4797
Emailjulien.micheled.acuk
Websitehttp://www.julienmichel.net

Accepting PhD Students

7 Active
21 Finished

28 results

Active

Trivector Cyclophilin Engagers as Immune-Oncology Adjuvants for Triple Negative Breast Cancer
Michel, J. & Doughty Shenton, D.
Engineering and Physical Sciences Research Council
1/06/23 → 31/10/24
Project: Research
Establishing the Accessible Computational Regimes for Biomolecular Simulations at Exascale
Michel, J., Marenduzzo, D. & Mey, A.
University of Leeds
1/06/23 → 30/11/24
Project: Research
Trivector Cyclophilin Engagers as Immune-Oncology Adjuvants for Triple Negative Breast Cancer
Doughty Shenton, D. & Michel, J.
Medical Research Council
1/06/23 → 31/10/24
Project: Research
Modelling protein covalent modifications with molecular simulation and machine learning
Michel, J.
Cresset Biomolecular Discovery Ltd
1/09/22 → 31/08/26
Project: Research
Supporting the OpenMM Community-led Development of Next-Generation Condensed Matter Modelling Software
Michel, J. & Grosser, T.
Engineering and Physical Sciences Research Council
1/04/22 → 21/01/26
Project: Research
A hybrid molecular simulation/machine-learning framework for rapid and accurate computation of absolute binding free energies of lead-like molecules
Michel, J.
Astra Zeneca
1/10/21 → 31/03/25
Project: Research
A high-throughput FEP pipeline for optimisation of hits into leads for novel drug targets
Michel, J.
Evotec (UK) Ltd
1/09/21 → 28/02/25
Project: Research
Finished

Predicting allostery for in-silico hit-ID
Michel, J.
Ucb Biopharma Srl
7/09/20 → 6/03/24
Project: Research
Predicting allostery for in-silico hit-ID
Michel, J.
Other
7/09/20 → 6/03/24
Project: Research
A modular software framework for accelerated generation of preclinical drug discovery assets
Michel, J.
Other
27/07/20 → 26/05/21
Project: Research
CYPNASH: Validation of a novel class of cyclophilin inhibitors for the treatment of non-alcoholic steatohepatitis
Michel, J.
EU government bodies
1/10/19 → 31/12/21
Project: Research
Cresset KTP - To develop a user friendly software for molecular simulations-driven computer-aided drug design
Michel, J.
UK industry, commerce and public corporations
3/09/18 → 2/12/19
Project: Research
Adaptive screening of chemical space via high-throughput binding free-energy calculations
Michel, J.
Cresset Biomolecular Discovery Ltd
1/09/18 → 30/08/22
Project: Research
Adaptive screening of chemical space via high-throughput binding free-energy calculations
Michel, J.
UK industry, commerce and public corporations
1/09/18 → 30/08/22
Project: Research
Methods and Applications of Ensemble-Based Drug Design
Michel, J.
UK-based charities
1/10/17 → 30/09/18
Project: Research
EPSRC Flagship Software - BioSimSpace A shared space for the community development of biomolecular simulation workflows
Michel, J.
EPSRC
7/08/17 → 6/02/20
Project: Research
A Software Interface for Interactive Ensemble-Based Drug Design
Michel, J.
EU government bodies
1/07/17 → 31/12/18
Project: Research
Efficient modelling and validation of cryptic protein binding sites for drug discovery
Michel, J.
EPSRC
1/07/17 → 31/12/21
Project: Research
Selective Protein Inhibition by Molecules Inducers of Protein Order
Michel, J.
UK-based charities
1/04/16 → 31/03/18
Project: Research
Explaining allosteric modulation of protein function by energy/entropy localisation
Michel, J.
UK industry, commerce and public corporations
1/10/15 → 30/09/19
Project: Research
Ensemble-based methods for drug design
Michel, J.
UK-based charities
1/10/15 → 30/09/18
Project: Research
ISOTRAPSS: Isoform specific inhibition by transient protein state stabilization
Michel, J.
EU government bodies
14/09/15 → 13/09/17
Project: Research
Beyond structure: integrated computational and experimental approach to Ensemble-Based Drug Design (EBDD)
Michel, J.
EU government bodies
1/12/13 → 30/11/18
Project: Research
Predictive modelling of ligand binding to flexible proteins
Michel, J.
EPSRC
1/03/13 → 28/02/15
Project: Research
Prediction and quantification of dynamic allostery in proteins
Michel, J.
Other (Learned Society)
1/04/12 → 31/03/14
Project: Research
QUANTITATIVE MODELS OF BIOMOLECULAR HYDRATION THERMODYNAMICS FOR RATIONAL DRUG DESIGN
Michel, J.
UK industry, commerce and public corporations
12/09/11 → 31/03/15
Project: Research
Discovering and exploiting hidden pockets at protein-protein interfaces
Michel, J.
EU government bodies
1/09/11 → 31/08/15
Project: Research
Small molecule control of intrinsically disordered protein function
Michel, J.
Other (Learned Society)
1/10/10 → 30/09/15
Project: Research