Research output per year
Research output per year
Personal profile
Biography
1. Autophagy as a novel therapeutic target in vascular calcification. 2. Role of dysfunctional mitochondria in vascular calcification diseases. 3. Selective clearance of lipid droplets by lipophagy reduces inflammation and mortality in farmed Atlantic salmon.
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Dive into the research topics where Kanchan Phadwal is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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TGF-β induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease
Tang, P., Markby, G., MacNair, A. J., Tang, K., Tkacz, M., Parys, M., Phadwal, K., MacRae, V. & Corcoran, B., 4 Mar 2023, (E-pub ahead of print) In: Cell proliferation. p. 1-23 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
p53 regulates mitochondrial dynamics in vascular smooth muscle cell calcification.
Phadwal, K., Tang, Q., Luijten, I., Zhao, J-F., Corcoran, B., Semple, R. K., Ganley, I. G. & MacRae, V., 13 Jan 2023, In: International Journal of Molecular Sciences. 24, 2, 1643.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Metformin protects against vascular calcification through the selective degradation of Runx2 by the p62 autophagy receptor
Phadwal, K., Koo, E., Jones, R. A., Forsythe, R., Tang, K., Tang, Q., Corcoran, B., Caporali, A. & MacRae, V., 27 Sep 2022, (E-pub ahead of print) In: Journal of Cellular Physiology. 237, 11, p. 4303-4316 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The Role of Transforming Growth Factor-β Signaling in Myxomatous Mitral Valve Degeneration
Tang, P., Mcnair, A., Phadwal, K., MacRae, V. & Corcoran, B., 17 May 2022, In: Frontiers in Cardiovascular Medicine. 9, 872288.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Mitochondrial Dysfunction: Cause or Consequence of Vascular Calcification?
Phadwal, K., Vrahnas, C., Ganley, I. G. & MacRae, V., 16 Mar 2021, In: Frontiers in Cell and Developmental Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
- 1 Finished
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Selective clearance of lipid droplets by lipophagy reduces inflammation and mortality in farmed Atlantic salmon.
1/03/21 → 31/05/22
Project: Research