Kat Bowles

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  Investigating the impact of ELAVL4 mislocalisation on splicing regulation in an iPSC-organoid model of frontotemporal dementia - NSCI

  Bowles, K.

  Neural Stem Cell Institute

  1/10/24 → 30/09/28

  Project: Research

• Investigating the impact of ELAVL4 mislocalisation on splicing regulation in an iPSC-organoid model of frontotemporal dementia

  Bowles, K.

  Medical Research Scotland

  1/10/24 → 30/09/28

  Project: Research

• Establishing and validating cell-type specific CRISPRi targeting in 3D cortical organoid models to investigate pathogenic mechanisms of tauopathy

  Bowles, K.

  Rainwater Charitable Foundation

  1/08/24 → 31/07/25

  Project: Research

• Using iPSC-organoids to investigate mitochondrial function and oxidative phosphorylation as early mechanisms of neuronal dysfunction in primary tauopathies

  Bowles, K.

  Royal Society

  1/03/24 → 31/08/25

  Project: Research

• Investigating mitochondrial dysfunction as an early pathogenic mechanism of primary tauopathies, using MAPT splicing mutation iPSC-organoids

  Bowles, K.

  CurePSP

  1/02/24 → 31/01/26

  Project: Research

• Understanding the role of astrocytic tau accumulation on glial and neuronal health in PSP

  Bowles, K.

  Rainwater Charitable Foundation

  1/01/24 → 31/12/25

  Project: Research

• Investigating the protective mechanisms of LRRC37A2 expression in iPSC models of Parkinson’s disease

  Bowles, K.

  Parkinson's UK

  1/09/23 → 28/02/26

  Project: Research

• Uncovering cell autonomous and non-cell autonomous effects of MAPT mutation and H1/H2 haplotypes in iPSC-neurons and astrocytes

  Bowles, K.

  Rainwater Charitable Foundation

  1/02/23 → 31/01/25

  Project: Research

• Single cell profiling of MAPT splicing mutation iPSC-derived organoids and brain tissue

  Bowles, K.

  BrightFocus Foundation

  1/09/22 → 30/06/25

  Project: Research

• UKDRI QQR - 1/4/23-31/3/28

  Hardingham, G., Bowles, K., Bowles, K., Chandran, S., Chandran, S., Diaz-Castro, B., Diaz-Castro, B., Gan, J., Gan, J., Hunt, D., Hunt, D., McColl, B., McColl, B., Montagne, A., Montagne, A., Opazo, P., Priller, J., Priller, J., Spires-Jones, T., Spires-Jones, T., Wardlaw, J. & Wardlaw, J.

  UK Dementia Research Institute Ltd

  1/07/22 → 31/03/28

  Project: Research