Research output per year
Research output per year
- 23 results
Search results
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2025
Rules of engagement for condensins and cohesins guide mitotic chromosome formation
Samejima, K., Gibcus, J. H., Abraham, S., Cisneros-Soberanis, F., Samejima, I., Beckett, A. J., Pucekova, N., Abad, M. A., Abad, M. A., Spanos, C., Medina-Pritchard, B., Paulson, J. R., Xie, L., Jeyaprakash, A. A., Prior, I. A., Mirny, L. A., Dekker, J., Goloborodko, A. & Earnshaw, W. C., 11 Apr 2025, In: Science. 388, 6743, 23 p., eadq1709 .Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2024
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin
Sacristan, C., Samejima, K., Ruiz, L. A., Deb, M., Lambers, M. L. A., Buckle, A., Brackley, C. A., Robertson, D., Hori, T., Webb, S., Kiewisz, R., Bepler, T., van Kwawegen, E., Risteski, P., Vukušić, K., Tolić, I. M., Müller-Reichert, T., Fukagawa, T., Gilbert, N. & Marenduzzo, D. & 2 others, , 6 Jun 2024, In: Cell. 187, 12, p. 3006-3023.e26 45 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2022
Mapping the invisible chromatin transactions of prophase chromosome remodeling
Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G. & Earnshaw, W. C., 3 Feb 2022, In: Molecular Cell. 82, 3, p. 696-708.e4 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Mapping the invisible chromatin transactions of prophase chromosome remodelling
Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G. & Earnshaw, W. C., 3 Feb 2022, In: Molecular Cell. 82, 3, p. 696-708.E4 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2019
Cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif requires Plk1
Papini, D., Fant, X., Ogawa, H., Desban, N., Samejima, K., Feizbakhsh, O., Askin, B., Ly, T., Earnshaw, W. C. & Ruchaud, S., 6 Nov 2019, (E-pub ahead of print) In: Journal of Cell Science. jcs.234401.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Two interlinked bistable switches govern mitotic control in mammalian cells
Rata, S., Suarez Peredo Rodriguez, M. F., Joseph, S., Peter, N., Echegaray Iturra, F., Yang, F., Madzvamuse, A., Ruppert, J. G., Samejima, K., Platani, M., Alvarez-Fernandez, M., Malumbres, M., Earnshaw, W. C., Novak, B. & Hochegger, H., 3 Dec 2018, In: Current Biology. 28, 23, p. 3824-3832.e6Research output: Contribution to journal › Article › peer-review
Open AccessFile -
An intrinsic S/G checkpoint enforced by ATR
Saldivar, J. C., Hamperl, S., Bocek, M. J., Chung, M., Bass, T. E., Cisneros-Soberanis, F., Samejima, K., Xie, L., Paulson, J. R., Earnshaw, W. C., Cortez, D., Meyer, T. & Cimprich, K. A., 24 Aug 2018, In: Science. 361, 6404, p. 806-810 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Seh1 targets GATOR2 and Nup153 to mitotic chromosomes
Platani, M., Samejima, I., Samejima, K., Kanemaki, M. T. & Earnshaw, W. C., 1 May 2018, In: Journal of Cell Science. 131, 9, 16 p., jcs213140.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry
Ruppert, J. G., Samejima, K., Platani, M., Molina, O., Kimura, H., Jeyaprakash, A. A., Ohta, S. & Earnshaw, W. C., 15 Mar 2018, In: EMBO Journal. 37, 6, 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis
Samejima, K., Booth, D. G., Ogawa, H., Paulson, J. R., Xie, L., Watson, C. A., Platani, M., Kanemaki, M. T. & Earnshaw, W. C., 22 Feb 2018, In: Journal of Cell Science. 131, 4, 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A pathway for mitotic chromosome formation
Gibcus, J. H., Samejima, K., Goloborodko, A., Samejima, I., Naumova, N., Nuebler, J., Kanemaki, M. T., Xie, L., Paulson, J. R., Earnshaw, W. C., Mirny, L. A. & Dekker, J., 9 Feb 2018, In: Science. 359, 6376, 14 p., eaao6135.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2016
Auxin/AID versus conventional knockouts: Distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability
Wood, L., Booth, D. G., Vargiu, G., Ohta, S., deLima Alves, F., Samejima, K., Fukagawa, T., Rappsilber, J. & Earnshaw, W. C., 20 Jan 2016, (E-pub ahead of print) In: Open Biology. 6, 1, 150230.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2015
The inner centromere protein (INCENP) coil is a single α-helix (SAH) domain that binds directly to microtubules and is important for chromosome passenger complex (CPC) localization and function in mitosis
Samejima, K., Platani, M., Wolny, M., Ogawa, H., Vargiu, G., Knight, P. J., Peckham, M. & Earnshaw, W. C., 28 Aug 2015, In: Journal of Biological Chemistry. 290, 35, p. 21460-21472 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development
González-Loyola, A., Fernández-Miranda, G., Trakala, M., Partida, D., Samejima, K., Ogawa, H., Cañamero, M., de Martino, A., Martínez-Ramírez, Á., de Cárcer, G., de Castro., I. P., Earnshaw, W. C. & Malumbres, M., 3 Aug 2015, (E-pub ahead of print) In: Molecular and Cellular Biology. 35, 20, p. 3566-3578 13 p.Research output: Contribution to journal › Article › peer-review
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2014
Auxin-induced rapid degradation of inhibitor of caspase-activated DNase (ICAD) induces apoptotic DNA fragmentation, caspase activation, and cell death: a cell suicide module
Samejima, K., Ogawa, H., Ageichik, A. V., Peterson, K. L., Kaufmann, S. H., Kanemaki, M. T. & Earnshaw, W. C., 7 Nov 2014, In: Journal of Biological Chemistry. 289, 45, p. 31617-31623 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery
Booth, D. G., Takagi, M., Sanchez-Pulido, L., Petfalski, E., Vargiu, G., Samejima, K., Imamoto, N., Ponting, C. P., Tollervey, D., Earnshaw, W. C. & Vagnarelli, P., 27 May 2014, In: eLIFE. 3, 22 p., e01641.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2012
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα
Samejima, K., Samejima, I., Vagnarelli, P., Ogawa, H., Vargiu, G., Kelly, D. A., Alves, F. L., Kerr, A., Ohta, S., Rappsilber, J., Earnshaw, W. C., Green, L. C., Hudson, D. F., Farr, C. J. & Cooke, C. A., 1 Nov 2012, In: Journal of Cell Biology. 199, 5, p. 755-770 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Contrasting roles of condensin I and condensin II in mitotic chromosome formation
Green, L. C., Kalitsis, P., Chang, T. M., Cipetic, M., Kim, J. H., Marshall, O., Choo, K. H. A., Hudson, D. F., Turnbull, L., Whitchurch, C. B., Vagnarelli, P., Samejima, K. & Earnshaw, W. C., 15 Mar 2012, In: Journal of Cell Science. 125, 6, p. 1591-1604 14 p.Research output: Contribution to journal › Article › peer-review
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2010
Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis
Xu, Z., Vagnarelli, P., Ogawa, H., Samejima, K. & Earnshaw, W. C., 17 Dec 2010, In: Journal of Biological Chemistry. 285, 51, p. 40163-40170 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2009
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization
Xu, Z., Ogawa, H., Vagnarelli, P., Bergmann, J. H., Hudson, D. F., Ruchaud, S., Earnshaw, W. C., Samejima, K. & Fukagawa, T., 30 Nov 2009, In: Journal of Cell Biology. 187, 5, p. 637-653 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2008
Apoptosis-associated caspase activation assays
Kaufmann, S. H., Meng, X. W., Loegering, D. A., Kottke, T. J., Lee, S.-H., Henzing, A. J., Ruchaud, S., Samejima, K. & Earnshaw, W. C., 1 Mar 2008, In: Methods. 44, 3, p. 262-272 11 p.Research output: Contribution to journal › Article › peer-review
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A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes
Samejima, K., Ogawa, H., Cooke, C. A., Hudson, D., MacIsaac, F., Ribeiro, S. A., Vagnarelli, P., Cardinale, S., Kerr, A., Lai, F. & Earnshaw, B., 2008, In: Proceedings of the National Academy of Sciences (PNAS). 105, 7, p. 2457-2462 1 p.Research output: Contribution to journal › Article › peer-review
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2000
Regulation of both apoptosis and cell survival by the v-Src oncoprotein
Johnson, D., Agochiya, M., Samejima, K., Earnshaw, W., Frame, M. & Wyke, J., Aug 2000, In: Cell Death & Differentiation (CDD). 7, 8, p. 685-96 12 p.Research output: Contribution to journal › Article › peer-review