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Personal profile

Biography

Email: kylie.matchett@ed.ac.uk

Research interests

Utilising a variety of tools including single cell sequencing, spatial transcriptomics, multiplex imaging and intravital imaging my research explores the mechanisms that are involved in regulating organ fibrosis and regeneration. I aim to define the microenvironmental cues arising from the regenerative niche, which instruct and differentially modulate parenchymal cell proliferation.

Moving forward, I am keen to engender a richly interdisciplinary research network. Combining experimental, computational and theoretical approaches through working with biologists, engineers, clinicians, physicists and bioinformaticians in order to gain a rich insight into organ biology in homeostasis and disease.

Biography

After obtaining my BSc(Hons) in Human Biology (1st class), I completed doctoral training between 2009 and 2013 at Queen Margaret University, Edinburgh. This investigated the effects of antioxidant compounds on adipocyte proliferation and differentiation in vitro, alongside a pilot study in obese individuals to determine the effectiveness of the intake of an encapsulated antioxidant concentrate at reducing plasma markers of inflammation in this population.

Following my PhD I obtained a Research Assistant position in Prof. Neil Henderson’s lab before moving to a postdoctoral position in 2014.

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