Research output per year
Research output per year
Personal profile
Current Research Interests
My research focuses on understanding how steroid hormones are produced (a process known as steroidogenesis) and defining the actions of different steroid hormones in the reproductive system. I am particularly interested in how and where the steroid hormones testosterone and estrogen act in the hypothalamus and pituitary gland.
Teaching
Zhejiang-Edinburgh Institute, Course organiser: Introduction to Cellular and Molecular Biology 1
http://www.drps.ed.ac.uk/19-20/dpt/cxibms08001.htm
University of Edinburgh, lecturer on BSc Biomedical Sciences courses:
Reproductive Biology 3
Gametes and Gonads 4
Endocrine physiology and pharmacology 4
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Research output
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Androgen Receptor is dispensable for X-zone regression in the female adrenal but regulates post- partum corticosterone levels and protects cortex integrity
Gannon, A., O'Hara, L., Mason, I., Jorgensen, A., Frederiksen, H., Curley, M., Milne, L., Smith, S., Mitchell, R. T. & Smith, L. B., 21 Jan 2021, In: Frontiers in Endocrinology.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterisation of a mural cell network in the murine pituitary gland
O'Hara, L., Christian, H., Jeffery, N., Le Tissier, P. & Smith, L. B., 31 Aug 2020, In: Journal of Neuroendocrinology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
Gannon, A., O'Hara, L., Mason, I., Rebourcet, D., Smith, S., Tavares, A., Corral, C. A., Frederiksen, H., Jorgensen, A., Mitchell, R. T. & Smith, L. B., 1 Mar 2019, In: Scientific Reports. 9, 3250.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Androgen receptor expression is required to ensure development of adult leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis
O'Shaughnessy, P. J., Mitchell, R., Monteiro, A., O'Hara, L., Cruickshanks, L., Claahsen-van der Grinten, H. L., Brown, P., Abel, M. & Smith, L., 17 Apr 2019, In: BMC Developmental Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
Gannon, A., O’hara, L., Mason, J. I., Jørgensen, A., Frederiksen, H., Milne, L., Smith, S., Mitchell, R. T. & Smith, L. B., 18 Jul 2019, In: Scientific Reports. 9, 1Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
- 2 Finished
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How does pituitary androgen signalling support lifelong health and wellbeing? An integrated transgenic and systems biology approach
Smith, L., Freeman, T., Le Tissier, P., O'Hara, L. & O'Hara, L.
1/04/16 → 31/03/19
Project: Research
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Determining the role of androgen receptor-signalling in the male pituitary
1/10/12 → 30/09/13
Project: Research