Lingzhao Fang

Search results

• 2021

  Genomic analysis revealed a convergent evolution of LINE-1 in coat color: A case study in water buffaloes (Bubalus bubalis)

  Liang, D., Zhao, P., Si, J., Fang, L., Pairo-Castineira, E., Hu, X., Xu, Q., Hou, Y., Gong, Y., Liang, Z., Tian, B., Mao, H., Yindee, M., Faruque, M., Kongvongxay, S., Khamphoumee, S., Liu, G., Wu, D-D., Barker, J., Han, J. & 1 others, Zhang, Y., Mar 2021, In: Molecular Biology and Evolution. 38, 3

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2020

  Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

  Zhou, Y., Liu, S., Hu, Y., Fang, L., Gao, Y., xia, H., Schroeder, S., Rosen, B., Connor, E., Li, C., Baldwin, R., Cole, J., Van Tassell, C., Yang, L., Ma, L. & Liu, G., 6 Jul 2020, In: BMC Biology. 18, 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle

  Fang, L., Cai, W., Liu, S., Canela Xandri, O., Gao, Y., Jiang, J., Rawlik, K., Li, B., Schroder, S. G., Rosen, B. D., Li, C., Sonstegard, T., Alexander, L. J., Van Tassell, C. P., Vanraden, P. M., Cole, J. W., Yu, Y., Zhang, S., Tenesa, A., Ma, L. & 1 others, Liu, G. E., 18 May 2020, (E-pub ahead of print) Genome Research.

  Research output: Contribution to specialist publication › Article

  Open Access

  File

  • transcriptome 100%
  • cattle 66%
  • tissues 48%
  • genes 33%
  • body conformation 21%

• Data of epigenomic profiling of histone marks and CTCF binding sites in bovine rumen epithelial primary cells before and after butyrate treatment

  Kang, X., Liu, S., Fang, L., Lin, S., Liu, M., Baldwin, R., Liu, G. & Li, C., 1 Feb 2020, In: Data in brief.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Epigenomics and Genotype-Phenotype Association Analyses Reveal Conserved Genetic Architecture of Complex Traits in Cattle and Human

  Liu, S., Yu, Y., Zhang, S., Cole, J. B., Tenesa, A., Wang, T., McDaneld, T. G., Ma, L., Liu, G. E. & Fang, L., 3 Jul 2020, (E-pub ahead of print) In: BMC Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • genotype-phenotype correlation 100%
  • Multifactorial Inheritance 84%
  • genotype 74%
  • phenotype 74%
  • Genetic Association Studies 73%

• Establishment and transcriptomic analyses of a cattle rumen epithelial primary cells (REPC) culture by bulk and single-cell RNA sequencing to elucidate interactions of butyrate treatment

  Lin, S., Fang, L., Kang, X., Liu, S., Liu, M., Connor, E., Baldwin, R., Liu, G. & Li, C-J., Jun 2020, In: Heliyon.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• GWAS and fine-mapping of livability and six disease traits in Holstein cattle

  Freebern, E., Santos, D., Fang, L., Jiang, J., Parker Gaddis, K., Liu, G., VanRaden, P., Maltecca, C., Cole, J. & Ma, L., 13 Jan 2020, In: BMC Genomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Impacts of colored light-emitting diode illumination on the growth performance and fecal microbiota in goose

  Li, X., Zheng, Z., Pan, J., Jiang, D., Tian, Y., Fang, L. & Huang, Y., Apr 2020, In: Poultry Science.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Integrating RNA-Seq with GWAS reveals novel insights into the molecular mechanism underpinning ketosis in cattle

  Yan, Z., Huang, H., Freebern, E., Santos, D., Dai, D., Si, J., Ma, C., Cao, J., Guo, G., Liu, G., Ma, L., Fang, L. & Zhang, Y., 17 Jul 2020, In: BMC Genomics. 21, 489.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Analyses of inter-individual variations of sperm DNA methylation and their potential implications in cattle

  Liu, S., Fang, L., Zhou, Y., Santos, D., Xiang, R., Daetwyler, H., Chamberlain, A., Cole, J., Li, C., Yu, Y., Ma, L., Zhang, S. & Liu, G., Dec 2019, In: BMC Genomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Array CGH-based detection of CNV regions and their potential association with reproduction and other economic traits in Holsteins

  Liu, M., Fang, L., Liu, S., Pan, M., Seroussi, E., Cole, J., Ma, L., Chen, H. & Liu, G., Dec 2019, In: BMC Genomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits

  Fang, L., Zhou, Y., Liu, S., Jiang, J., Bickhart, D., Null, D., Li, B., Schroeder, S., Rosen, B., Cole, J., Van Tassell, C., Ma, L. & Liu, G., 4 Mar 2019, In: Epigenetics.

  Research output: Contribution to journal › Article › peer-review

• Computational detection and experimental validation of segmental duplications and associated copy number variations in water buffalo (Bubalus bubalis)

  Liu, S., Kang, X., Catacchio, C., Liu, M., Fang, L., Schroeder, S., Li, W., Rosen, B., Iamartino, D., Iannuzzi, L., Sonstegard, T., Van Tassell, C., Ventura, M., Low, W., Williams, J., Bickhart, D. & Liu, G., 1 May 2019, In: Functional & integrative genomics.

  Research output: Contribution to journal › Article › peer-review

• Diversity of copy number variation in the worldwide goat population

  Liu, M., Zhou, Y., Rosen, B., Van Tassell, C., Stella, A., Tosser-Klopp, G., Rupp, R., Palhière, I., Colli, L., Sayre, B., Crepaldi, P., Fang, L., Mészáros, G., Chen, H. & Liu, G., May 2019, In: Heredity.

  Research output: Contribution to journal › Article › peer-review

• Estimation of the genetic parameters for semen traits in Chinese Holstein bulls

  Yin, H., Fang, L., Qin, C. & Zhang, S., 10 Jun 2019, In: BMC Genetics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

  Fang, L., Liu, S., Liu, M., Kang, X., Lin, S., Li, B., Connor, E. E., Baldwin VI, R. L., Tenesa, A., Ma, L., Liu, G. E. & Li, C-J., 16 Aug 2019, In: BMC Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Butyrates 100%
  • butyrates 82%
  • cattle 79%
  • Rumen 79%
  • genome 75%

• Genetic and epigenetic architecture of paternal origin contribute to gestation length in cattle

  Fang, L., Jiang, J., Li, B., Zhou, Y., Freebern, E., Vanraden, P., Cole, J., Liu, G. & Ma, L., 14 Mar 2019, In: Communications biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• High-density genome-wide association study for residual feed intake in Holstein dairy cattle

  Li, B., Fang, L., Null, DJ., Hutchison, JL., Connor, EE., VanRaden, PM., VandeHaar, MJ., Tempelman, RJ., Weigel, KA. & Cole, JB., 1 Dec 2019, In: Journal of Dairy Science.

  Research output: Contribution to journal › Article › peer-review

• Integrating signals from sperm methylome analysis and genome-wide association study for a better understanding of male fertility in cattle

  Fang, L., Zhou, Y., Liu, S., Jiang, J., Bickhart, D., Null, D., Li, B., Schroeder, S., Rosen, B., Cole, J., Van Tassell, C., Ma, L. & Liu, G., 16 May 2019, In: Epigenomes.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Weighted single-step genome-wide association study of semen traits in Holstein bulls of China

  Yin, H., Zhou, C., Shi, S., Fang, L., Liu, J-F., Sun, D., Li, J. & Zhang, S., 25 Oct 2019, In: Frontiers in genetics.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Genome-wide association study of Mycobacterium avium subspecies paratuberculosis infection in Chinese Holstein

  Gao, Y., Jiang, J., Yang, S., Cao, J., Han, B., Wang, Y., Zhang, Y., Yu, Y., Zhang, S., Zhang, Q., Fang, L., Cantrell, B. & Sun, D., 27 Dec 2018, In: BMC Genomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• MicroRNA-guided prioritization of genome-wide association signals reveals the importance of microRNA-target gene networks for complex traits in cattle

  Fang, L., Sørensen, P., Sahana, G., Panitz, F., Su, G., Zhang, S., Yu, Y., Li, B., Ma, L., Liu, G., Sandø Lund, M. & Thomsen, B., 19 Jun 2018, In: Scientific Reports.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The cholesterol-deficiency associated mutation in APOB segregates at low frequency in Chinese Holstein cattle

  Li, Y., Fang, L., Liu, L., Zhang, S., Ma, Z. & Sun, D., 16 Oct 2018, In: Canadian Journal of Animal Science.

  Research output: Contribution to journal › Article › peer-review
• 2017

  Exploring the genetic architecture and improving genomic prediction accuracy for mastitis and milk production traits in dairy cattle by mapping variants to hepatic transcriptomic regions responsive to intra-mammary infection

  Fang, L., Sahana, G., Ma, P., Su, G., Yu, Y., Zhang, S., Sandø Lund, M. & Sørensen, P., 1 Dec 2017, In: Genetics Selection Evolution. 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Integrating sequence-based GWAS and RNA-Seq provides novel insights into the genetic basis of mastitis and milk production in dairy cattle

  Fang, L., Sahana, G., Su, G., Yu, Y., Zhang, S., Sandø Lund, M. & Sørensen, P., 30 Mar 2017, In: Scientific Reports.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds

  Fang, L., Sahana, G., Ma, P., Su, G., Yu, Y., Zhang, S., Sandø Lund, M. & Sørensen, P., 10 Aug 2017, In: BMC Genomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2016

  Genome-wide transcriptional and post-transcriptional regulation of innate immune and defense responses of bovine mammary gland to Staphylococcus aureus

  Fang, L., Hou, Y., An, J., Li, B., Song, M., Wang, X., Sorensen, P., Dong, Y., Wang, Y., Zhu, H., Zhang, S. & Yu, Y., 26 Dec 2016, In: Frontiers in Cellular and Infection Microbiology.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2015

  Screening for JH1 genetic defect carriers in Jersey cattle by a polymerase chain reaction and restriction fragment length polymorphism assay

  Zhang, Y., Guo, G., Huang, H., Lu, L., Wang, L., Fang, L., Liu, L., Wang, Y. & Zhang, S., Sep 2015, In: Journal of Veterinary Diagnostic Investigation.

  Research output: Contribution to journal › Article › peer-review

• 2013

  Identification of brachyspina syndrome carriers in Chinese Holstein cattle

  Fang, L., Li, Y., Zhang, Y., Sun, D., Liu, L., Zhang, Y. & Zhang, S., Jul 2013, In: Journal of Veterinary Diagnostic Investigation.

  Research output: Contribution to journal › Article › peer-review