Research output per year
Research output per year
Personal profile
Biography
I have graduated from University of Warmia and Mazury in Olsztyn, Poland in 2009. Subsequently I worked in private practice. In 2010 I have started PhD at Michigan State University, College of Veterinary Medicine. During my PhD I was studying immunomodulatory properties of feline mesenchymal stem cells and their clinical application in chronic feline idiopathic cystitis. In 2016 I relocated to R(D)SVS to start a clinical lecturership position, which combines work in small animal internal medicine with research on identifying novel approaches to cancer immunotherapy. My research interests also include therapeutic use of stem cells in companion animals, use of next generation sequencing to identify disease causing genetic variants and pathways involved in disease pathogenesis in companion animals. In 2016 I was awarded an AVMA/AVMF Young Investigator Award for work on immunomodulatory properties of feline mesenchymal stem cells. In 2017 I was awarded an ABCD and Boeringher Ingelheim Young Scientist Award.
Research Interests
Cancer immunotherapy, therapeutic use of mesenchymal stem cells, immunology, personalized medicine, use of next generation sequencing to identify disease causing variants and pathways
Current Research Interests
My current research interests include studying the role of immune checkpoints in canine and feline cancer and inflammatory disease. I am also intereted in interactions between innate and adaptive immune system in cancer patients.
Education/Academic qualification
Doctor of Philosophy (PhD), Evaluation of immunomodulatory properties of feline mesenchymal stem cells and their clinical application in treatment of feline chronic idiopathic cystitis , Michigan State University
2010 → 2016
Lekarz weterynarii (DVM), University of Warmia and Mazury
2004 → 2009
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Development of a Canine Single-chain Phage Antibody Library to Isolate Recombinant Antibodies for use in Translational Cancer Research
Lisowska , M., Worralll, E. G., Zavadil Kokáš, F., Charlton, K., Murray, E., Mohtar, M. A., Krejcir, R., Hrabal, V., Brydon, J., Gonzalez Urionabarrenetxea, A., Saliba, D., Grima, M., Kalathiya, U., Muller, P., Krejci, A., Vojtěšek, B., Ball, K. L., Fahraeus, R., Argyle, D. & Parys, M. & 1 others, , 24 Mar 2025, (E-pub ahead of print) In: Cell Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy
Blacklock, K. L. B., Donnelly, K., Lu, Y., Pozo, J. D., Glendinning, L., Polton, G., Selmic, L., Tanis, J.-B., Killick, D., Parys, M., Morris, J. S., Breathnach, I., Zago, S., Gould, S. M., Shaw, D. J., Tivers, M. S., Malucelli, D., Marques, A., Purzycka, K. & Cantatore, M. & 4 others, , Mar 2025, In: Journal of Pathology. 265, 3, p. 245-259 15 p.Research output: Contribution to journal › Article › peer-review
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Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Tang, Q., Tang, K. T., Markby, G., Parys, M., Phadwal, K., MacRae, V. & Corcoran, B., 2025, In: Autophagy. 21, 7, p. 1433-1455 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
PD‑1 interactome in osteosarcoma: identification of a novel PD‑1/AXL interaction conserved between humans and dogs
Dziubek, K., Faktor, J., Lokhande, K. B., Shrivastava, A., Papak, I., Chruściel, E., Pilch, M., Hupp, T., Marek-Trzonkowska, N., Singh, A., Parys, M. & Kote, S., 18 Dec 2024, In: Cell communication and signaling. 22, 1, p. 1-30 30 p., 605.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Paraneoplastic leukocytosis in a dog following liposarcoma resection
Cutler, S., Blackwood, L., Pratschke, K., Parys, M., Philbey, A., Spyropoulou , M., Starybrat, D. & Breheny, C., Jun 2024, In: Vet Record Case Reports. 12, 2, p. 1-9 9 p., e848.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 3 Oral presentation
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A simplified and accurate CT-volumetry method for the canine liver
Israeliantz Gunz, N. (Speaker), Lodzinska, J. (Contributor), Woods, G. A. (Contributor), Pontes, J. (Contributor), Parys, M. (Contributor) & Schwarz, T. (Contributor)
17 Sept 2020Activity: Academic talk or presentation types › Oral presentation
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Dynamic 4D-CTEU is a reliable technique to investigate ureteral ectopia in dogs
Longo, M. (Speaker), Bommer, N. (Contributor), Parys, M. (Contributor), Thierry, F. (Contributor), Bouvard, J. (Contributor), Perez Accino Salgado, J. (Contributor) & Schwarz, T. (Contributor)
1 Nov 2019Activity: Academic talk or presentation types › Oral presentation
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CT features of feline lipiduria and renal cortical lipid deposition
Schwarz, T. (Speaker), Shorten, E. (Contributor), Longo, M. (Contributor), Saunders, J. (Contributor), Gennace, M. (Contributor), Gunn-Moore, D. (Contributor) & Parys, M. (Contributor)
1 Nov 2019Activity: Academic talk or presentation types › Oral presentation
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Genome-wide CRISPR knockout screening to identify molecular vulnerabilities in feline oral squamous cell carcinoma
Parkinson, N. (Principal Investigator) & Parys, M. (Co-investigator)
1/01/23 → 31/12/25
Project: Research
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T-cell receptor rearrangements as a potential diagnostic tool in feline infectious peritonitis
Malbon, A. (Principal Investigator), Connelley, T. (Co-investigator) & Parys, M. (Co-investigator)
1/01/23 → 31/01/24
Project: Research
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Acute phase protein and micro RNA signatures for the diagnosis and prognosis of feline infectious peritonitis
Gunn-Moore, D. (Principal Investigator), Malbon, A. (Co-investigator) & Parys, M. (Co-investigator)
Petsavers, British Small Animal Veterinary Association
1/07/22 → 30/09/24
Project: Research
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Feasibility study into mass spectrometric analysis of effusions as a tool in the diagnosis and understanding of feline infectious peritonitis
Malbon, A. (Principal Investigator), Gunn-Moore, D. (Co-investigator) & Parys, M. (Co-investigator)
1/01/22 → 31/12/22
Project: Research
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Feasibility study into mass spectrometric analysis of effusions as a tool in the diagnosis and understanding of feline infectious peritonitis
Malbon, A. (Principal Investigator), Gunn-Moore, D. (Co-investigator) & Parys, M. (Co-investigator)
1/01/22 → 31/12/22
Project: Research