Research output per year
Research output per year
Personal profile
Biography
I have graduated from University of Warmia and Mazury in Olsztyn, Poland in 2009. Subsequently I worked in private practice. In 2010 I have started PhD at Michigan State University, College of Veterinary Medicine. During my PhD I was studying immunomodulatory properties of feline mesenchymal stem cells and their clinical application in chronic feline idiopathic cystitis. In 2016 I relocated to R(D)SVS to start a clinical lecturership position, which combines work in small animal internal medicine with research on identifying novel approaches to cancer immunotherapy. My research interests also include therapeutic use of stem cells in companion animals, use of next generation sequencing to identify disease causing genetic variants and pathways involved in disease pathogenesis in companion animals. In 2016 I was awarded an AVMA/AVMF Young Investigator Award for work on immunomodulatory properties of feline mesenchymal stem cells. In 2017 I was awarded an ABCD and Boeringher Ingelheim Young Scientist Award.
Research Interests
Cancer immunotherapy, therapeutic use of mesenchymal stem cells, immunology, personalized medicine, use of next generation sequencing to identify disease causing variants and pathways
Current Research Interests
My current research interests include studying the role of immune checkpoints in canine and feline cancer and inflammatory disease. I am also intereted in interactions between innate and adaptive immune system in cancer patients.
Education/Academic qualification
Doctor of Philosophy (PhD), Evaluation of immunomodulatory properties of feline mesenchymal stem cells and their clinical application in treatment of feline chronic idiopathic cystitis , Michigan State University
2010 → 2016
Lekarz weterynarii (DVM), University of Warmia and Mazury
2004 → 2009
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The immunopeptidome from a genomic perspective: Establishing the noncanonical landscape of MHC class I–associated peptides
Bedran, G., Gasser, H-C., Weke, K., Wang, T., Bedran, D., Laird, A., Battail, C., Zanzotto, F. M., Pesquita, C., Axelson, H., Rajan, A., Harrison, D. J., Palkowski, A., Pawlik, M., Parys, M., O'Neill, J. R., Brennan, P. M., Symeonides, S. N., Goodlett, D. R., Litchfield, K., & 4 others, 24 Mar 2023, (E-pub ahead of print) In: Cancer Immunology Research. p. 1-40 39 p., 22-0621.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
TGF-β induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease
Tang, P., Markby, G., MacNair, A. J., Tang, K., Tkacz, M., Parys, M., Phadwal, K., MacRae, V. & Corcoran, B., 4 Mar 2023, (E-pub ahead of print) In: Cell proliferation. p. 1-23 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Use of multi-color flow cytometry for canine immune cell characterization in cancer
Parys, M., Bavcar, S., Mellanby, R. J., Argyle, D. & Kitamura, T., Mar 2023, In: PLoS ONE. 18, 3, p. 1-15 15 p., e0279057.Research output: Contribution to journal › Article › peer-review
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Development of monoclonal antibodies targeting canine PD-L1 and PD-1 and their clinical relevance in Canine Apocrine Gland Anal Sac Adenocarcinoma
Minoli, L., Licenziato, L., Kocikowski, M., Cino, M., Dziubek, K., Iussich, S., Fanelli, A., Morello, E., Martano, M., Hupp, T. R., Vojtesek, B., Parys, M. & Aresu, L., 14 Dec 2022, (E-pub ahead of print) In: Cancers. 14, 24, 6188.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Design, synthesis and biological evaluation of PD-1 derived peptides as inhibitors of PD-1/PD-L1 complex formation for cancer therapy
Bojko, M., Węgrzyn, K., Sikorska, E., Kocikowski, M., Parys, M., Battin, C., Steinberger, P., Kogut, M. M., Winnicki, M., Sieradzan, A. K., Spodzieja, M. & Rodziewicz-Motowidło, S., Nov 2022, In: Bioorganic Chemistry. 128, p. 1-15 106047.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 3 Oral presentation
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A simplified and accurate CT-volumetry method for the canine liver
Nicolas Israeliantz Gunz (Speaker), Joanna Lodzinska (Contributor), Glynn Alan Woods (Contributor), Joana Pontes (Contributor), Maciej Parys (Contributor) & Tobias Schwarz (Contributor)
17 Sep 2020Activity: Academic talk or presentation types › Oral presentation
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CT features of feline lipiduria and renal cortical lipid deposition
Tobias Schwarz (Speaker), Eimear Shorten (Contributor), Maurizio Longo (Contributor), Jimmy Saunders (Contributor), Marisa Gennace (Contributor), Danielle Gunn-Moore (Contributor) & Maciej Parys (Contributor)
1 Nov 2019Activity: Academic talk or presentation types › Oral presentation
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Dynamic 4D-CTEU is a reliable technique to investigate ureteral ectopia in dogs
Maurizio Longo (Speaker), Nicholas Bommer (Contributor), Maciej Parys (Contributor), Florence Thierry (Contributor), Jonathan Bouvard (Contributor), Jorge Perez Accino Salgado (Contributor) & Tobias Schwarz (Contributor)
1 Nov 2019Activity: Academic talk or presentation types › Oral presentation