Research output per year
Research output per year
- 43 results
Search results
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2024
COVID-19 plasma induces subcellular remodelling within the pulmonary microvascular endothelium
Passi, R., Cholewa-Waclaw, J., Wereski, R., Bennett, M., Veizades, S., Berkeley, B., Caporali, A., Li, Z., Rodor, J., Dewerchin, M., Mills, N. L., Beqqali, A., Brittan, M. & Baker, A. H., 1 Mar 2024, In: Vascular pharmacology. 154, 107277.Research output: Contribution to journal › Article › peer-review
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PAR4 Antagonism in Patients With Coronary Artery Disease Receiving Antiplatelet Therapies
Nash, J., Meah, M. N., Whittington, B., Debono, S., Raftis, J., Miller, M. R., Sorbie, A., Mills, N. L., Nespoux, J., Bruce, L., Duffin, R., Dhaun, N., Brittan, M., Chao, L., Merali, S., Kim, M., Wang, Z., Zhang, Y., Jin, S., Wang, B., & 2 others, 15 Feb 2024, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 44, 4, p. 987-996Research output: Contribution to journal › Article › peer-review
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2023
Clonal Expansion in Cardiovascular Pathology
Lin, A., Brittan, M., Baker, A. H., Dimmeler, S., Fisher, E. A., Sluimer, J. & Misra, A., 19 Jul 2023, (E-pub ahead of print) In: JACC: Basic to Translational Science.Research output: Contribution to journal › Review article › peer-review
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A Multimodal Omics Framework to Empower Target Discovery for Cardiovascular Regeneration
Li, Z., Brittan, M. & Mills, N. L., 8 Jul 2023, In: Cardiovascular Drugs and Therapy.Research output: Contribution to journal › Article › peer-review
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The role of the endothelium in SARS-CoV-2 infection and pathogenesis
Passi, R., Brittan, M. & Baker, A. H., 1 Apr 2023, In: Current opinion in physiology. 34, 100670.Research output: Contribution to journal › Article › peer-review
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2022
Human embryonic stem cell-derived endothelial cell product injection attenuates cardiac remodeling in myocardial infarction
Spiroski, A-M., McCracken, I., Thomson, A., Magalhaes Pinto, M., Lalwani, M. K., Newton, K., Miller, E., Benezech, C., Hadoke, P. W. F., Brittan, M., Mountford, J. C., Beqqali, A., Gray, G. A. & Baker, A. H., 10 Oct 2022, In: Frontiers in Cardiovascular Medicine.Research output: Contribution to journal › Article › peer-review
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Multi-species meta-analysis identifies transcriptional signatures associated with cardiac endothelial responses in the ischaemic heart
Li, C., Solomonidis, E., Berkeley, B., Tang, M., Ross Stewart, K., Perez-Vicencio, D., McCracken, I., Spiroski, A-M., Gray, G. A., Barton, A., Sellers, S. L., Riley, P. R., Baker, A. H. & Brittan, M., 9 Sept 2022, (E-pub ahead of print) In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration
Bruton, F., Kaveh, A., Ross Stewart, K., Matrone, G., Oremek, M., Solomonidis, E., Tucker, C., Mullins, J., Lucas, C. D., Brittan, M., Taylor, J. M., Rossi, A. G. & Denvir, M. A., 9 Jun 2022, In: Developmental Cell. 57, 12, p. 1512-1528Research output: Contribution to journal › Article › peer-review
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Mapping the developing human cardiac endothelium at single cell resolution identifies MECOM as a regulator of arteriovenous gene expression
McCracken, I., Dobie, R., Bennett, M., Passi, R., Beqqali, A., Henderson, N. C., Mountford, J. C., Riley, P. R., Ponting, C. P., Smart, N., Brittan, M. & Baker, A. H., 25 Feb 2022, In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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2021
Single-cell RNA-seq profiling of mouse endothelial cells in response to pulmonary arterial hypertension
Rodor, J., Chen, S. H., Scanlon, J. P., Monteiro, J. P., Caudrillier, A., Sweta, S., Ross Stewart, K., Shmakova, A., Dobie, R., Henderson, B. EP., Stewart, K., Hadoke, P. W. F., Southwood, M., Moore, S. D., Upton, P. D., Morrell, N. W., Li, Z., Chan, S. Y., Handen, A., Lafyatis, R., & 6 others, 16 Sept 2021, In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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Hooked on heart regeneration: the zebrafish guide to recovery
Ross Stewart, K. M., Walker, S. L., Baker, A. H., Riley, P. R. & Brittan, M., 23 Jun 2021, In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
Open Access -
Dissecting the transcriptome in cardiovascular disease
Robinson, E., Baker, A. H., Brittan, M., McCracken, I., Condorelli, G., Emanueli, C., Srivastava, KP., Gaetano, C., Thum, T., Vanhaverbeke, M., Angione, C., Heymans, S., Devaux, Y., Pedrazzini, T. & Martelli, F., 23 Mar 2021, (E-pub ahead of print) In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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Generation of a Novel In Vitro Model to Study Endothelial Dysfunction from Atherothrombotic Specimens
Gallogly, S., Fujisawa, T., Hung, J. D., Brittan, M., Skinner, E. M., Mitchell, A. J., Medine, C., Luque, N., Zodda, E., Cascante, M., Hadoke, P. W., Mills, N. L. & Tura-Ceide, O., 20 Feb 2021, (E-pub ahead of print) In: Cardiovascular Drugs and Therapy.Research output: Contribution to journal › Article › peer-review
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The Influence of the LINC00961/SPAAR Locus Loss on Murine Development, Myocardial Dynamics, and Cardiac Response to Myocardial Infarction
Spiroski, A-M., Sanders, R., Meloni, M., McCracken, I., Thomson, A. J. W., Brittan, M., Gray, G. A. & Baker, A. H., 19 Jan 2021, (E-pub ahead of print) In: International Journal of Molecular Sciences.Research output: Contribution to journal › Article › peer-review
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2020
Extracellular Vesicle miRNAs in the Promotion of Cardiac Neovascularisation
Kesidou, D., Da Costa Martins, P. A., De Windt, L. J., Brittan, M., Beqqali, A. & Baker, A. H., 25 Sept 2020, (E-pub ahead of print) In: Frontiers in physiology.Research output: Contribution to journal › Review article › peer-review
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Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy
Martello, A., Lauriola, A., Mellis, D., Parish, E., Dawson, J. C., Imrie, L., Vidmar, M., Gammoh, N., Mitić, T., Brittan, M., Mills, N. L., Carragher, N. O., D'arca, D. & Caporali, A., 26 Apr 2020, (E-pub ahead of print) In: EMBO Reports.Research output: Contribution to journal › Article › peer-review
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The LINC00961 transcript and its encoded micropeptide SPAAR regulate endothelial cell function
Spencer, H. L., Sanders, R., Boulberdaa, M., Meloni, M., Cochrane, A., Spiroski, A., Mountford, J., Emanueli, C., Caporali, A., Brittan, M., Rodor, J. & Baker, A. H., 28 Jan 2020, In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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2019
Endothelial Progenitor Cells Do Not Originate From the Bone Marrow
Fujisawa, T., Tura-Ceide, O., Hunter, A., Mitchell, A., Vesey, A., Medine, C., Gallogly, S., Hadoke, P. W. F., Keith, C., Sproul, A., Roddie, H., McQuaker, G., Wilmut, I., Mills, N. L. & Brittan, M., 29 Oct 2019, In: Circulation. 140, 18, p. 1524-1526 3 p.Research output: Contribution to journal › Article › peer-review
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Single cell transcriptome analyses reveal novel targets modulating cardiac neovascularisation by resident endothelial cells following myocardial infarction
Li, Z., Solomonidis, E. G., Meloni, M., Taylor, R. S., Duffin, R., Dobie, R., Magalhaes, M. S., Henderson, B. E. P., Louwe, P. A., D'amico, G., Hodivala-Dilke, K. M., Shah, A. M., Mills, N. L., Simons, B. D., Gray, G. A., Henderson, N. C., Baker, A. H. & Brittan, M., 7 Aug 2019, In: European Heart Journal. 40, 30, p. 2507–2520 14 p.Research output: Contribution to journal › Article › peer-review
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2017
Endothelial Progenitor Cell Biology and Vascular Recovery Following Transradial Cardiac Catheterization
Mitchell, A., Fujisawa, T., Mills, N. L., Brittan, M., Newby, D. E. & Cruden, N. L. M., 28 Oct 2017, In: Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease. 6, 11Research output: Contribution to journal › Article › peer-review
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Fire Simulation and Cardiovascular Health in Firefighters
Hunter, A. L., Shah, A. S. V., Langrish, J. P., Raftis, J. B., Lucking, A. J., Brittan, M., Venkatasubramanian, S., Stables, C. L., Stelzle, D., Marshall, J., Graveling, R., Flapan, A. D., Newby, D. E. & Mills, N. L., 4 Apr 2017, In: Circulation. 135, 14, p. 1284-1295 12 p.Research output: Contribution to journal › Article › peer-review
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2016
A role for the long non-coding RNA SENCR in commitment and function of endothelial cells
Boulberdaa, M., Elizabeth, S., Margaret, B., Raquel, G., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A. L., Mcbride, M. W., Mcclure, J. D., Miano, J. M., Emanueli, C., Mills, N., Mountford, J. C. & Baker, A., 5 Apr 2016, (E-pub ahead of print) In: Molecular Therapy.Research output: Contribution to journal › Article › peer-review
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2015
Impaired vascular function and repair in patients with premature coronary artery disease
Brittan, M., Hunter, A., Boulberdaa, M., Fujisawa, T., Skinner, E. M., Shah, A. SV., Baker, A. H. & Mills, N. L., Dec 2015, In: European Journal of Preventive Cardiology. 22, 12, p. 1557-1566Research output: Contribution to journal › Article › peer-review
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IDENTIFICATION OF THE ORIGIN OF CIRCULATING ENDOTHELIAL PROGENITOR CELLS
Fujisawa, T., Brittan, M., Tura-Ceide, O., Hunter, A., Mitchell, A., Vesey, A., Skinner, E. M., Medine, C., Gallogly, S., Hadoke, P. W. F., Keith, C., Sproul, A., Roddie, H., McQuaker, G., Wilmut, I. & Mills, N. L., Jul 2015, In: Atherosclerosis. 241, 1, p. E44-E44 1 p.Research output: Contribution to journal › Meeting abstract
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2014
Serial characterisation of monocyte and neutrophil function after lung resection
Jones, R. O., Brittan, M., Anderson, N. H., Conway Morris, A., Murchison, J. T., Walker, W. S. & Simpson, A. J., 16 Sept 2014, In: BMJ Open Respiratory Research. 1, 1, 8 p., e000045.Research output: Contribution to journal › Article
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Differential response to bacteria, and TOLLIP expression, in the human respiratory tract
Moncayo-nieto, O. L., Wilkinson, T. S., Brittan, M., Mchugh, B. J., Jones, R. O., Conway Morris, A., Walker, W. S., Davidson, D. J. & Simpson, A. J., 11 Sept 2014, In: BMJ Open Respiratory Research. 1, 1, p. e000046-e000046Research output: Contribution to journal › Article › peer-review
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Isolation and characterisation of coronary endothelial outgrowth cells from patients undergoing revascularisation for acute myocardial infarction
Gallogly, S., Skinner, E., Fujisawa, T., Allcock, R., Tura, O., Brittan, M. & Mills, N. L., 1 Sept 2014, In: European Heart Journal. 35, p. 614-614 1 p.Research output: Contribution to journal › Meeting abstract
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Premature coronary artery disease is associated with vascular and endothelial cell dysfunction
Hunter, A. L., Brittan, M., Skinner, E. M., Fujisawa, T., Gallogly, S., Shah, A. S., Langrish, J. P., Raftis, J. B. & Mills, N. L., 1 Sept 2014, In: European Heart Journal. 35, p. 1047-1048 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation
Brittan, M., Barr, L. C., Anderson, N., Conway-Morris, A., Duffin, R., Marwick, J. A., Rossi, F., Johnson, S., Dhaliwal, K., Hirani, N., Rossi, A. G. & Simpson, A. J., 31 Mar 2014, In: Journal of inflammation. 11, 1, 9.Research output: Contribution to journal › Article › peer-review
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Innate immune responses after resection for lung cancer via video-assisted thoracoscopic surgery and thoracotomy
Jones, R. O., Anderson, N. H., Murchison, J. T., Brittan, M., Simon, E. J., Casali, G., Simpson, A. J. & Walker, W. S., 1 Mar 2014, In: Innovations:Technology and Techniques in Cardiothoracic and Vascular Surgery. 9, 2, p. 93-103; discussion 103Research output: Contribution to journal › Article › peer-review
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Reply: The alveolar macrophage and acute respiratory distress syndrome: a silent actor?
Barr, L. C., Brittan, M., Morris, A. C., McAuley, D. F., McCormack, C., Fletcher, A. M., Richardson, H., Connell, M., Patel, D., Wallace, W. A. H., Rossi, A. G., Davidson, D. J., Manson, L., Turner, M., Hirani, N., Walsh, T. S., Anderson, N. H., Dhaliwal, K. & Simpson, A. J., 15 Feb 2014, In: American Journal of Respiratory and Critical Care Medicine. 189, 4, p. 500-1 2 p.Research output: Contribution to journal › Letter › peer-review
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2013
Endothelial progenitor cells in patients with chronic obstructive pulmonary disease
Brittan, M., Hoogenboom, M. M., Padfield, G. J., Tura, O., Fujisawa, T., MacLay, J. D., MacNee, W. & Mills, N. L., Dec 2013, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 305, 12, p. L964-L969 6 p.Research output: Contribution to journal › Article › peer-review
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Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients
Morris, A. C., Anderson, N., Brittan, M., Wilkinson, T. S., McAuley, D. F., Antonelli, J., McCulloch, C., Barr, L. C., Dhaliwal, K., Jones, R. O., Haslett, C., Hay, A. W., Swann, D. G., Laurenson, I. F., Davidson, D. J., Rossi, A. G., Walsh, T. S. & Simpson, A. J., Nov 2013, In: British Journal of Anaesthesia. 111, 5, p. 778-787 10 p.Research output: Contribution to journal › Article › peer-review
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Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments
Marwick, J. A., Dorward, D. A., Lucas, C. D., Jones, K. O., Sheldrake, T. A., Fox, S., Ward, C., Murray, J., Brittan, M., Hirani, N., Duffin, R., Dransfield, I., Haslett, C. & Rossi, A. G., 20 Aug 2013, In: Journal of Leukocyte Biology. 94, 6, p. 1285-1292Research output: Contribution to journal › Article › peer-review
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A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation
Barr, L. C., Brittan, M., Conway Morris, A., McAuley, D. F., McCormack, C., Fletcher, A. M., Richardson, H., Connell, M., Patel, D., Wallace, W., Rossi, A. G., Davidson, D. J., Manson, L., Turner, M., Hirani, N., Walsh, T. S., Anderson, N. H., Dhaliwal, K. & Simpson, A. J., Aug 2013, In: American Journal of Respiratory and Critical Care Medicine. 188, 4, p. 449-455Research output: Contribution to journal › Article › peer-review
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Isolation and characterisation of endothelial outgrowth from coronary arteries in patients with acute myocardial infarction
Brittan, M., Gallogly, S. & Mills, N. L., Aug 2013, In: European Heart Journal. 34, p. 113-113 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Late Outgrowth Endothelial Cells Resemble Mature Endothelial Cells and Are Not Derived from Bone Marrow
Tura, O., Skinner, E. M., Robin Barclay, G., Samuel, K., Gallagher, R. C., Brittan, M., Hadoke, P. W., Newby, D. E., Turner, M. L. & Mills, N. L., Feb 2013, In: STEM CELLS. 31, 2, p. 338-348 11 p.Research output: Contribution to journal › Article › peer-review
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2012
Pulmonary and systemic effects of mononuclear leukapheresis
Barr, L., Brittan, M., Conway-Morris, A., Stewart, A., Dhaliwal, K., Anderson, N., Turner, M., Manson, L. & Simpson, J., Nov 2012, In: Vox Sanguinis. 103, 4, p. 275-283 9 p.Research output: Contribution to journal › Article › peer-review
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A novel subpopulation of monocyte-like cells in the human lung after LPS inhalation
Brittan, M., Barr, L., Conway Morris, A., Duffin, R., Rossi, F., Johnston, S., Monro, G., Anderson, N., Rossi, A. G., McAuley, D. F., Haslett, C., Hirani, N., Dhaliwal, K. & Simpson, A. J., 2012, In: European Respiratory Journal. 40, 1, p. 206-214 9 p.Research output: Contribution to journal › Article › peer-review
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2011
C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients
Morris, A. C., Brittan, M., Wilkinson, T. S., McAuley, D. F., Antonelli, J., McCulloch, C., Barr, L. C., McDonald, N. A., Dhaliwal, K., Jones, R., Mackellar, A., Haslett, C., Hay, A. W., Swann, D. G., Anderson, N., Laurenson, I. F., Davidson, D. J., Rossi, A. G., Walsh, T. S. & Simpson, A. J., 12 May 2011, In: Blood. 117, 19, p. 5178-5188 11 p.Research output: Contribution to journal › Article › peer-review
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2010
MONOCYTE INFLUX ACCOMPANIES THE EARLY NEUTROPHILIC INFLAMMATION SEEN IN BRONCHOALVEOLAR LAVAGE FLUID FOLLOWING LIPOPOLYSACCHARIDE INHALATION
Barr, L. C., Brittan, M., Morris, A. C., Johnston, S., Rossi, F., Duffini, R., Hirani, N., Dhaliwal, K., Rossi, A. G., McAuley, D. F. & Simpson, J., Dec 2010, In: Thorax. 65, p. A48-A48 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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PRIMARY TYPE II ALVEOLAR EPITHELIAL CELLS RESPOND DIFFERENTIALLY TO BACTERIAL VIRULENCE FACTORS
Moncayo Nieto, O. L., Brittan, M., Wilkinson, T. S., Morris, A. C., Dhaliwal, K., Walker, W. S. & Simpson, J., Dec 2010, In: Thorax. 65, p. A38-A38 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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C5A MEDIATED NEUTROPHIL DYSFUNCTION PRECEDES AND PREDICTS NOSOCOMIAL INFECTION IN CRITICAL ILLNESS
Morris, A. C., Antonelli, J., Brittan, M., McCulloch, C., Laurenson, I., Swann, D. G., Hay, A., Walsh, T. S. & Simpson, J., Sept 2010, In: Intensive Care Medicine. 36, p. S290-S290 1 p.Research output: Contribution to journal › Meeting abstract › peer-review