Marcus Wilson

DR

Accepting PhD Students

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Personal profile

Biography

2005-2009 MBiochem University of Oxford, UK

2009-2013 PhD CRUK LRI Clare Hall laboratories, London, UK

2013-2016 Postdoc SLRI Mount Sinai Hospital, Toronto, Canada

2016-2018 Postdoc Francis Crick Institute, London, UK

2018-present Sir Henry Dale Fellow and Lecturer in Structural Cell Biology, University of Edinburgh

Websites

Research Interests

We are interested in understanding how epigenetic marks are placed, read and interpreted on chromatin. Chromatin becomes decorated with post-translational modifications to control the myriad of DNA-related processes in the cell. We create modified chromatin using chemical biology and biochemical methods. We then use our defined modified chromatin to study individual nucleosome-chromatin protein complexes using single-particle cryo-electron microscopy (cryo-EM),  Biochemical, Biophysical and Cell Biology approaches to investigate histone marks and DNA methylation.

 

  1. How is DNA Methylation guided by chromatin?

  2. How do post-translational modifications foster DNA repair?

  3. What is the structure of chromatin in diverse eukaryotes?

Positions available

If you are interested in joining our group please contact Marcus with a CV to discuss potential opportunities.

A number of fully funded PhD studentships are available for both UK/EU and worldwide students. Please get in touch if you are interested.

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