Research output per year
Research output per year
- 22 results
Search results
-
2022
High salt intake activates the hypothalamic-pituitary-adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice
Costello, H., Krilis, G., Grenier, C., Severs, D., Czopek, A., Ivy, J. R., Nixon, M., Holmes, M. C., Livingstone, D. E. W., Hoorn, E. J., Dhaun, N. & Bailey, M. A., 11 Nov 2022, (E-pub ahead of print) In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The ATP-binding cassette proteins ABCB1 and ABCC1 as modulators of glucocorticoid action
Devine, K., Villalobos, E., Kyle, C., Andrew, R., Reynolds, R. M., Stimson, R. H., Nixon, M. & Walker, B. R., 11 Oct 2022, (E-pub ahead of print) In: Nature reviews endocrinology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans
Kyle, C. J., Nixon, M., Homer, N. Z. M., Morgan, R. A., Andrew, R., Stimson, R. H. & Walker, B. R., 1 Mar 2022, In: Metabolism. 128, 155118.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2021
Glucocorticoids: Fuelling the Fire of Atherosclerosis or Therapeutic Extinguishers?
Macleod, C., Hadoke, P. W. F. & Nixon, M., 16 Jul 2021, (E-pub ahead of print) In: International Journal of Molecular Sciences. 22, 14, p. 7622Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Bell, R., Villalobos, E., Nixon, M., Miguelez-Crespo1, A., Murphy, L., Fawkes, A., Coutts, A., Sharp, M. G., Koerner, M., Allan, E., Meijer, O. C., Houtman, R., Odermatt, A., Beck, K. R., Denham, S., Lee, P., Homer, N., Walker, B. R. & Morgan, R. A., 27 Mar 2021, (E-pub ahead of print) In: Molecular Metabolism.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2020
Effects of Obesity And Insulin on Tissue-Specific Recycling Between Cortisol And Cortisone in Men
Anderson, A., Andrew, R., Homer, N. Z. M., Hughes, K., Boyle, L., Nixon, M., Karpe, F., Stimson, R. H. & Walker, B., 3 Dec 2020, (E-pub ahead of print) In: The Journal of Clinical Endocrinology & Metabolism (JCEM).Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants
Jackson-Jones, L. H., Smith, P., Portman, J. R., Magalhaes, M. S., Mylonas, K. J., Vermeren, M. M., Nixon, M., Henderson, B. E. P., Dobie, R., Vermeren, S., Denby, L., Henderson, N. C., Mole, D. J. & Bénézech, C., 14 Apr 2020, In: Immunity. 52, 4, p. 700-715.e6Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2019
Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography triple quadrupole mass spectrometry
Verma, M., Sooy, K., Just, G., Nixon, M., Morgan, R., Andrew, R., Chapman, K. & Homer, N., 2 Nov 2019, In: Rapid communications in mass spectrometry.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta
Wieczorek, A., Perani, C. V., Nixon, M., Constancia, M., Sandovici, I., Zazara, D. E., Leone, G., Zhang, M. Z., Arck, P. C. & Solano, M. E., 1 Jul 2019, In: American Journal of Physiology-Endocrinology and Metabolism . 317, 1, p. E109-E120Research output: Contribution to journal › Article › peer-review
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Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
Mak, T. C., Livingstone, D. E., Nixon, M., Walker, B. R. & Andrew, R., 14 Jun 2019, In: Endocrinology .Research output: Contribution to journal › Article › peer-review
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Androgens modulate glucocorticoid receptor activity in adipose tissue and liver
Spaanderman, D. C. E., Nixon, M., Buurstede, J. C., Sips, H. H. C. M., Schilperoort, M., Kuipers, E. N., Backer, E. A., Kooijman, S., Rensen, P. C. N., Homer, N. Z. M., Walker, B. R., Meijer, O. C. & Kroon, J., Jan 2019, (E-pub ahead of print) In: Journal of Endocrinology . 240, 1, p. 51-63Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Dysregulation of cortisol metabolism in equine pituitary pars intermedia dysfunction
Morgan, R. A., Keen, J. A., Homer, N., Nixon, M., McKinnon-Garvin, A. M., Moses-Williams, J. A., Davis, S. R., Hadoke, P. W. F. & Walker, B. R., 4 Oct 2018, (E-pub ahead of print) In: Endocrinology . 159, 11, p. 3791–3800 10 p.Research output: Contribution to journal › Article › peer-review
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2017
Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity
Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J., & 4 others, 6 Sept 2017, In: Scientific Reports. 7, 1, 10633.Research output: Contribution to journal › Article › peer-review
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2016
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: a rationale for safer glucocorticoid replacement therapy
Nixon, M., Mackenzie, S. D., Taylor, A. I., Homer, N. Z. M., Livingstone, D. E., Mouras, R., Morgan, R. A., Mole, D. J., Stimson, R. H., Reynolds, R. M., Elfick, A. P. D., Andrew, R. & Walker, B. R., 17 Aug 2016, In: Science Translational Medicine. 8, 352, 12 p., 352ra109.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation
Ramage, L. E., Akyol, M., Fletcher, A. M., Forsythe, J., Nixon, M., Carter, R. N., van Beek, E. J. R., Morton, N. M., Walker, B. R. & Stimson, R. H., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 130-141 12 p.Research output: Contribution to journal › Article › peer-review
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Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity
Nixon, M., Stewart-Fitzgibbon, R., Fu, J., Akhmedov, D., Rajendran, K., Mendoza-Rodriguez, M. G., Rivera-Molina, Y. A., Gibson, M., Berglund, E. D., Justice, N. J. & Berdeaux, R., 1 Jan 2016, In: Molecular Metabolism. 5, 1, p. 34-46 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
When two glucocorticoids are better than one: 'Relative corticosterone deficiency' in human metabolic syndrome
Mackenzie, S., Nixon, M., Taylor, A., Reynolds, R., Bolton, J., Hayward, C., Wilson, J., Philips, D., Homer, N., Andrew, R. & Walker, B., Nov 2015, In: Psychoneuroendocrinology. 61, p. 29-29 1 p.Research output: Contribution to journal › Meeting abstract
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2012
Salicylate Downregulates 11β-HSD1 Expression in Adipose Tissue in Obese Mice and in Humans, Mediating Insulin Sensitization
Nixon, M., Wake, D. J., Livingstone, D. E., Stimson, R. H., Esteves, C. L., Seckl, J. R., Chapman, K. E., Andrew, R. & Walker, B. R., Apr 2012, In: Diabetes . 61, 4, p. 790-796 7 p.Research output: Contribution to journal › Article › peer-review
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5α-Reduced glucocorticoids: a story of natural selection
Nixon, M., Upreti, R. & Andrew, R., Feb 2012, In: Journal of Endocrinology. 212, 2, p. 111-127 17 p.Research output: Contribution to journal › Article › peer-review
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It takes two to tango: Dimerisation of glucocorticoid receptor and its anti-inflammatory functions
Nixon, M., Andrew, R. & Chapman, K. E., 2012, In: Steroids. 78, 1, p. 59-68 10 p.Research output: Contribution to journal › Article › peer-review
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2011
5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects
Yang, CHENYING., Nixon, M., Kenyon, C. J., Livingstone, D. E. W., Duffin, R., Rossi, A. G., Walker, B. R. & Andrew, R., 2011, In: British Journal of Pharmacology. 164, 6, p. 1661-71 11 p.Research output: Contribution to journal › Article › peer-review
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2010
Salicylate-Induced Insulin Sensitisation in Obesity Is Mediated through Downregulation of Omental Adipose 11 beta-Hydroxysteroid Dehydrogenase Type 1.
Nixon, M., Livingstone, D. E., Andrew, R. & Walker, B. R., Jun 2010, In: Endocrine Reviews. 31, 3, p. S2474-S2474 1 p.Research output: Contribution to journal › Meeting abstract › peer-review