Mathew Horrocks

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• Active

  Single-vesicle profiling as a route to early diagnosis of motor neurone disease.

  Horrocks, M. (Principal Investigator) & Saleeb, R. (Co-investigator)

  Tenovus Scotland

  12/08/24 → 11/02/26

  Project: Research

• Using AI to assess senescence and mitochondrial morphology in calcifying VSMCs

  MacRae, V. (Principal Investigator) & Horrocks, M. (Co-investigator)

  BBSRC

  14/02/24 → 13/02/26

  Project: Research

• Establishment of a point of care test to detect TDP-43 pathology in faecal samples

  Horrocks, M. (Principal Investigator)

  University of Aberdeen

  1/11/23 → 31/10/26

  Project: Research

• Single-molecule detection of cryptic exons related to amyotrophic lateral sclerosis (ALS)

  Horrocks, M. (Principal Investigator)

  The AnBer Foundation

  1/10/23 → 31/03/27

  Project: Research

• A single-molecule characterisation of ALS-FTSD neuropathology to identify biomarkers of clinical heterogeneity

  Horrocks, M. (Principal Investigator)

  Motor Neurone Disease Association

  1/04/23 → 31/03/26

  Project: Research

• Synaptic pathology in ALS-FTD

  Horrocks, M. (Principal Investigator), Grant, S. (Co-investigator) & Smith, C. (Co-investigator)

  Medical Research Council

  7/02/23 → 6/02/26

  Project: Research

• Probing RNA-binding protein aggregates at the nanoscale using in silico designed aptamers

  Horrocks, M. (Principal Investigator)

  Target ALS

  1/12/22 → 28/02/26

  Project: Research

• Transmembrane Rotary Motors

  Cockroft, S. (Principal Investigator) & Horrocks, M. (Co-investigator)

  Leverhulme Trust

  1/04/22 → 25/07/25

  Project: Research

• Investigating the link between neuronal innate immunity and Parkinson’s disease

  Horrocks, M. (Principal Investigator)

  OXFORD NANOIMAGING LIMITED

  1/10/21 → 30/09/25

  Project: Research

• Investigating the link between neuronal innate immunity and Parkinson¿s disease

  Horrocks, M. (Principal Investigator)

  UK-based charities

  1/10/21 → 30/09/25

  Project: Research

  • Midbrain 100%
  • Familial Parkinson's Disease 100%
  • Dopaminergic Neuron 100%
  • Protein Aggregation 100%
  • Dopaminergic 100%

• Investigating the link between neuronal innate immunity and Parkinson�s disease

  Horrocks, M. (Principal Investigator)

  Medical Research Scotland

  1/10/21 → 30/09/25

  Project: Research

• Finished

  Optimising CNS extracellular vesicle capture as a method to improve early detection of neurodegenerative diseases

  Horrocks, M. (Principal Investigator) & Saleeb, R. (Co-investigator)

  Wellcome Trust (Rcl)

  1/07/24 → 30/09/24

  Project: Research

• Single-molecule real-time quaking-induced conversion assay for the diagnosis and stratification of synucleinopathies - EPSRC IAA Collaborative Call

  Horrocks, M. (Principal Investigator)

  Ucb Biopharma Srl

  1/02/23 → 30/11/23

  Project: Research

• Single-molecule real-time quaking-induced conversion assay for the diagnosis and stratification of synucleinopathies - EPSRC IAA Collaborative Call

  Horrocks, M. (Principal Investigator)

  University of Edinburgh

  1/02/23 → 30/11/23

  Project: Research

• The Physical Biology Of Neurodegeneration In Sporadic Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

  Horrocks, M. (Principal Investigator)

  The Trustees of Columbia University in the City of New York

  1/09/21 → 31/08/24

  Project: Research

• Characterising amyloid protein conformers and associated proteins in situ using single-molecule imaging

  Horrocks, M. (Principal Investigator)

  UK-based charities

  1/07/21 → 30/06/22

  Project: Research

• Single-molecule detection of alpha synuclein aggregates in biofluids

  Horrocks, M. (Principal Investigator)

  Ucb Biopharma Srl

  1/01/21 → 31/12/22

  Project: Research

• Single-molecule detection of alpha synuclein aggregates in biofluids

  Horrocks, M. (Principal Investigator)

  Other

  1/01/21 → 31/12/22

  Project: Research

• CoEN5025 NANOSYN: Unravelling synaptic pathology in Alzheimer's disease and Dementia with Lewy bodies using super-resolution microscopy

  Spires-Jones, T. (Principal Investigator) & Horrocks, M. (Co-investigator)

  Medical Research Council

  15/08/20 → 13/11/23

  Project: Research

• CoEN5025 NANOSYN: Unravelling synaptic pathology in Alzheimer's disease and Dementia with Lewy bodies using super-resolution microscopy

  Spires-Jones, T. (Principal Investigator) & Horrocks, M. (Co-investigator)

  MRC

  15/08/20 → 14/08/22

  Project: Research

• Single-molecule detection of tau aggregates in biofluids

  Horrocks, M. (Principal Investigator)

  Other

  1/06/20 → 31/05/23

  Project: Research

• Single-molecule detection of tau aggregates in biofluids

  Horrocks, M. (Principal Investigator)

  Ucb Biopharma Srl

  1/06/20 → 31/05/23

  Project: Research

• Full Spectrum Fluorescence Lifetime Imaging in Brain Tissue

  Horrocks, M. (Principal Investigator)

  UK-based charities

  31/03/20 → 30/03/22

  Project: Research

• The nanoscopic characterisation of cellular protein aggregates formed in patients with familial Parkinson's disease

  Horrocks, M. (Principal Investigator)

  UK-based charities

  1/09/18 → 31/08/21

  Project: Research

• Single-molecule detection of protein aggregates under flow

  Horrocks, M. (Principal Investigator) & Vendrell Escobar, M. (Co-investigator)

  UK-based charities

  18/07/18 → 17/07/19

  Project: Research

  • Synuclein 100%
  • Alpha-Synuclein 66%
  • Oligomerization 50%
  • Mitochondrion 50%
  • Cardiolipin 33%

• New tools to detect and characterise protein aggregates at the nanoscale in biological samples and in human neurons

  Hardingham, G. (Principal Investigator), Horrocks, M. (Co-investigator) & Kunath, T. (Co-investigator)

  UK industry, commerce and public corporations

  9/02/18 → 30/04/19

  Project: Research