Research output per year
Research output per year
Personal profile
Current Research Interests
My research is currently focused on the development of advanced MR imaging techniques and their application in neurological diseases.
Disease areas:
- Cerebral small vessel disease
- Multiple sclerosis
- Pre-term birth
Techniques:
- Quantitative magnetic resonance imaging of the brain
- Dynamic contrast-enhanced MRI (DCE-MRI) for probing the blood-brain barrier
- MR cerebrovascular reactivity imaging
- MR imaging of fluid flow
- MR spectroscopy and brain temperature measurement
- MR relaxometry
- Magnetisation transfer
- MR phantom development
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Dive into the research topics where Michael Thrippleton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Comparison of CVR Magnitude and Delay Assessed at 1.5 and 3T in Patients With Cerebral Small Vessel Disease
Stringer, M. S., Blair, G. W., Shi, Y., Hamilton, I., Dickie, D. A., Doubal, F. N., Marshall, I. M., Thrippleton, M. J. & Wardlaw, J. M., 2 Jun 2021, (E-pub ahead of print) In: Frontiers in physiology. 12Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage
Bernal, J., Valdés-hernández, M. D. C., Escudero, J., Heye, A. K., Sakka, E., Armitage, P. A., Makin, S., Touyz, R. M., Wardlaw, J. M. & Thrippleton, M. J., 23 Jan 2021, (E-pub ahead of print) In: NeuroImage. 230, p. 117786Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Associations Between White Matter Hyperintensity Burden, Cerebral Blood Flow and Transit Time in Small Vessel Disease: An Updated Meta-Analysis
Stewart, C. R., Stringer, M. S., Shi, Y., Thrippleton, M. J. & Wardlaw, J. M., 4 May 2021, In: Frontiers in Neurology. 12Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Cerebrovascular Reactivity Measurement Using Magnetic Resonance Imaging: A Systematic Review
Sleight, E., Stringer, M. S., Marshall, I., Wardlaw, J. M. & Thrippleton, M. J., 25 Feb 2021, In: Frontiers in physiology. 12Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
Microbleeds International Collaborative Network, Best, J. G., Ambler, G., Wilson, D., Lee, K., Lim, J., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-sanchez, L., Martínez-domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S. & 31 others, , 17 Mar 2021, (E-pub ahead of print) In: The Lancet Neurology. 20, 4, p. 294-303Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 1 Oral presentation
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Comparison of five quantitative analysis methods for the assessment of subtle blood-brain barrier permeability using DCE-MRI
Maria Valdes Hernandez (Contributor), Anna K. Heye (Speaker), Michael Thrippleton (Contributor), Paul Armitage (Contributor) & Joanna Wardlaw (Contributor)
3 Oct 2013Activity: Academic talk or presentation types › Oral presentation
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Wellcome Trust, INSTITUTIONAL STRATEGIC SUPPORT FUND: Investigating mechanisms of brain and cognitive development in children born preterm
Richardson, H., Bastin, M., Thrippleton, M., Fletcher-Watson, S. & Boardman, J.
1/03/21 → 28/02/22
Project: University Awarded Project Funding
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Magnetic resonance imaging (MRI) of brain vascular changes and white matter hyperintensities (WMH) in humans
Meijboom, R., Thrippleton, M., Waldman, A. & Wardlaw, J.
1/04/18 → 31/03/19
Project: Research
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Establishing a protocol for post-mortem MR-pathological correlation for studies of ageing, neurodegeneration and cerebrovascular disease
Valdes Hernandez, M., Wardlaw, J., Smith, C., Marshall, I., Thrippleton, M. & Jansen, M.
1/01/12 → 30/06/13
Project: University Awarded Project Funding
Datasets
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A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage: source code
Bernal Moyano, J. (Creator), Valdes Hernandez, M. (Creator), Armitage, P. (Creator), Makin, S. (Creator), Touyz, R. M. (Creator), Wardlaw, J. (Creator), Thrippleton, M. (Creator), Sakka, E. (Creator), Escudero Rodriguez, J. (Creator) & Heye, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2966, https://www.preprints.org/manuscript/202010.0200/v1
Dataset
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Methods to quantify and visualize venules using structural magnetic resonance imaging scans
Jochems, A. (Creator), Blair, G. (Creator), Stringer, M. (Creator), Thrippleton, M. (Creator), Clancy, U. (Creator), Chappell, F. (Creator), Brown, R. (Creator), Jaime García, D. (Creator), Hamilton, O. (Creator), Morgan, A. (Creator), Marshall, I. (Creator), Hetherington, K. (Creator), Wiseman, S. (Creator), MacGillivray, T. (Creator), Valdes Hernandez, M. (Creator), Doubal, F. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 21 Jan 2020
DOI: 10.7488/ds/2755
Dataset
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White Matter Hyperintensities Evolution Patterns 1 Year Post-lacunar Stroke and their association with post-stroke cognition
Thrippleton, M. (Creator), Valdes Hernandez, M. (Creator), Grimsley-Moore, T. (Creator), Sakka, E. (Creator), Chappell, F. (Creator), Armitage, P. (Creator), Makin, S. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 23 Jun 2021
DOI: 10.7488/ds/3063, https://doi.org/10.3389/fneur.2021.634460
Dataset
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MATLAB-based framework for simulating DCE-MRI of subtle blood-brain barrier breakdown
Manning, C. (Creator) & Thrippleton, M. (Creator), Edinburgh DataShare, 9 Mar 2021
DOI: 10.7488/ds/2997
Dataset
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Magnetisation transfer saturation (MTsat) processing
York, B. (Creator), Thrippleton, M. (Creator) & Waldman, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2965
Dataset