Research output per year
Research output per year
Personal profile
Current Research Interests
My research is currently focused on the development of advanced MR imaging techniques and their application in neurological diseases.
Disease areas:
- Cerebral small vessel disease
- Multiple sclerosis
- Pre-term birth
Techniques:
- Quantitative magnetic resonance imaging of the brain
- Dynamic contrast-enhanced MRI (DCE-MRI) for probing the blood-brain barrier
- MR cerebrovascular reactivity imaging
- MR imaging of fluid flow
- MR spectroscopy and brain temperature measurement
- MR relaxometry
- Magnetisation transfer
- MR phantom development
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A daily temperature rhythm in the human brain predicts survival after brain injury
Rzechorzek, N., Thrippleton, M. J., Chappell, F. M., Mair, G., Ercole, A., Cabeleira, M., Rhodes, J., Marshall, I. & O'Neill, J. S., 13 Jun 2022, In: Brain.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Quantitative magnetisation transfer imaging in relapsing-remitting multiple sclerosis: a systematic review and meta-analysis
York, E. N., Thrippleton, M. J., Meijboom, R., Hunt, D. P. J. & Waldman, A. D., 4 Apr 2022, In: Brain Communications.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
General factors of white matter microstructure from DTI and NODDI in the developing brain
Vaher, K., Galdi, P., Cabez, M. B., Sullivan, G., Stoye, D. Q., Quigley, A. J., Thrippleton, M. J., Bogaert, D., Bastin, M. E., Cox, S. R. & Boardman, J. P., 1 Apr 2022, (E-pub ahead of print) In: NeuroImage. p. 119169Research output: Contribution to journal › Article › peer-review
Open Access -
DNA methylation in relation to gestational age and brain dysmaturation in preterm infants
Wheater, E. N., Galdi, P., McCartney, D. L., Blesa Cabez, M., Sullivan, G., Stoye, D., Lamb, G. J., Sparrow, S., Murphy, L., Wrobel, N., Quigley, A. J., Semple, S. I. K., Thrippleton, M. J., Wardlaw, J. M., Bastin, M. E., Marioni, R. E., Cox, S. R. & Boardman, J. P., 8 Mar 2022, (E-pub ahead of print) In: Brain Communications.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of Cilostazol and Isosorbide Mononitrate on Cerebral Hemodynamics in the LACI-1 Randomized Controlled Trial
Blair, G. W., Janssen, E., Stringer, M. S., Thrippleton, M. J., Chappell, F., Shi, Y., Hamilton, I., Flaherty, K., Appleton, J. P., Doubal, F. N., Bath, P. M. & Wardlaw, J. M., 1 Dec 2021, (E-pub ahead of print) In: Stroke.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 1 Oral presentation
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Comparison of five quantitative analysis methods for the assessment of subtle blood-brain barrier permeability using DCE-MRI
Maria Valdes Hernandez (Contributor), Anna K. Heye (Speaker), Michael Thrippleton (Contributor), Paul Armitage (Contributor) & Joanna Wardlaw (Contributor)
3 Oct 2013Activity: Academic talk or presentation types › Oral presentation
Projects
- 3 Finished
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Wellcome Trust, INSTITUTIONAL STRATEGIC SUPPORT FUND: Investigating mechanisms of brain and cognitive development in children born preterm
Richardson, H., Bastin, M., Thrippleton, M., Fletcher-Watson, S. & Boardman, J.
1/03/21 → 28/02/22
Project: University Awarded Project Funding
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Magnetic resonance imaging (MRI) of brain vascular changes and white matter hyperintensities (WMH) in humans
Meijboom, R., Thrippleton, M., Waldman, A. & Wardlaw, J.
1/04/18 → 31/03/19
Project: Research
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Establishing a protocol for post-mortem MR-pathological correlation for studies of ageing, neurodegeneration and cerebrovascular disease
Valdes Hernandez, M., Wardlaw, J., Smith, C., Marshall, I., Thrippleton, M. & Jansen, M.
1/01/12 → 30/06/13
Project: University Awarded Project Funding
Datasets
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Methods to quantify and visualize venules using structural magnetic resonance imaging scans
Jochems, A. (Creator), Blair, G. (Creator), Stringer, M. (Creator), Thrippleton, M. (Creator), Clancy, U. (Creator), Chappell, F. (Creator), Brown, R. (Creator), Jaime García, D. (Creator), Hamilton, O. (Creator), Morgan, A. (Creator), Marshall, I. (Creator), Hetherington, K. (Creator), Wiseman, S. (Creator), MacGillivray, T. (Creator), Valdes Hernandez, M. (Creator), Doubal, F. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 21 Jan 2020
DOI: 10.7488/ds/2755
Dataset
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A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage: source code
Bernal Moyano, J. (Creator), Valdes Hernandez, M. (Creator), Armitage, P. (Creator), Makin, S. (Creator), Touyz, R. M. (Creator), Wardlaw, J. (Creator), Thrippleton, M. (Creator), Sakka, E. (Creator), Escudero Rodriguez, J. (Creator) & Heye, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2966, https://www.preprints.org/manuscript/202010.0200/v1
Dataset
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Cerebrovascular Reactivity MRI Protocol - Figures
Thrippleton, M. (Creator), Shi, Y. (Creator), Blair, G. (Creator), Hamilton, I. (Creator), Waiter, G. (Creator), Schwarzbauer, C. (Creator), Pernet, C. (Creator), Andrews, P. (Creator), Marshall, I. (Creator), Doubal, F. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 8 Aug 2017
DOI: 10.7488/ds/2110
Dataset
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Magnetisation transfer saturation (MTsat) processing
York, B. (Creator), Thrippleton, M. (Creator) & Waldman, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2965
Dataset
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MATLAB-based framework for simulating DCE-MRI of subtle blood-brain barrier breakdown
Manning, C. (Creator) & Thrippleton, M. (Creator), Edinburgh DataShare, 9 Mar 2021
DOI: 10.7488/ds/2997
Dataset