Research output per year
Research output per year
Personal profile
Current Research Interests
My research is currently focused on the development of advanced MR imaging techniques and their application in neurological diseases.
Disease areas:
- Cerebral small vessel disease
- Multiple sclerosis
- Pre-term birth
Techniques:
- Quantitative magnetic resonance imaging of the brain
- Dynamic contrast-enhanced MRI (DCE-MRI) for probing the blood-brain barrier
- MR cerebrovascular reactivity imaging
- MR imaging of fluid flow
- MR spectroscopy and brain temperature measurement
- MR relaxometry
- Magnetisation transfer
- MR phantom development
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Dive into the research topics where Michael Thrippleton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Patterns of brain atrophy in recently-diagnosed relapsing-remitting multiple sclerosis
Meijboom, R., York, E. N., Kampaite, A., Harris, M. A., White, N., Valdés Hernández, M. D. C., Thrippleton, M. J., MacDougall, N. J. J., Connick, P., Hunt, D. P. J., Chandran, S., Waldman, A. D. & FutureMS Consortium, 28 Jul 2023, In: PLoS ONE. 18, 7, p. e0288967Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Paranasal sinuses opacification on magnetic resonance imaging in relation to brain health in sporadic small vessel disease – Systematic review and pilot analysis
Sáenz de Villaverde Cortabarría, A., Zhang, J., Valdés Hernández, M. C., Wu, Y., Clancy, U., Sakka, E., Ferguson, K., Wiseman, S., Hewins, W., Jaime Garcia, D., Stringer, M., Thrippleton, M. J., Chappell, F. M., Doubal, F., Wu, Y., Wardlaw, J. M. & the Mild Stroke Study 3 (MSS3) study group, 17 Jul 2023, (E-pub ahead of print) In: Journal of the Neurological Sciences.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Examining temporal features of BOLD-based cerebrovascular reactivity in clinical populations
Marchena-Romero, K-J., Ji, X., Sommer, R., Centen, A., Ramirez, J., Poulin, J. M., Mikulis, D., Thrippleton, M., Wardlaw, J., Lim, A., Black, S. E. & MacIntosh, B. J., 15 Jun 2023, In: Frontiers in Neurology. 14, p. 1199805Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques
Sennfält, S., Thrippleton, M. J., Stringer, M., Reyes, C. A., Chappell, F., Doubal, F., Garcia, D. J., Zhang, J., Cheng, Y. & Wardlaw, J., 31 May 2023, In: Journal of Cerebral Blood Flow and Metabolism. p. 0271678X2311795Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Repeatability and comparison of 2D and 4D flow MRI measurement of intracranial blood flow and pulsatility in healthy individuals and patients with cerebral small vessel disease
Morgan, A. G., Thrippleton, M. J., Stringer, M., Jin, N., Wardlaw, J. M. & Marshall, I., 30 May 2023, In: Frontiers in Psychology. 14Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
- 1 Oral presentation
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Comparison of five quantitative analysis methods for the assessment of subtle blood-brain barrier permeability using DCE-MRI
Maria Valdes Hernandez (Contributor), Anna K. Heye (Speaker), Michael Thrippleton (Contributor), Paul Armitage (Contributor) & Joanna Wardlaw (Contributor)
3 Oct 2013Activity: Academic talk or presentation types › Oral presentation
Projects
- 3 Finished
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Wellcome Trust, INSTITUTIONAL STRATEGIC SUPPORT FUND: Investigating mechanisms of brain and cognitive development in children born preterm
Richardson, H., Bastin, M., Thrippleton, M., Fletcher-Watson, S. & Boardman, J.
1/03/21 → 28/02/22
Project: University Awarded Project Funding
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Magnetic resonance imaging (MRI) of brain vascular changes and white matter hyperintensities (WMH) in humans
Meijboom, R., Thrippleton, M., Waldman, A. & Wardlaw, J.
1/04/18 → 31/03/19
Project: Research
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Establishing a protocol for post-mortem MR-pathological correlation for studies of ageing, neurodegeneration and cerebrovascular disease
Valdes Hernandez, M., Wardlaw, J., Smith, C., Marshall, I., Thrippleton, M. & Jansen, M.
1/01/12 → 30/06/13
Project: University Awarded Project Funding
Datasets
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A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage: source code
Bernal Moyano, J. (Creator), Valdes Hernandez, M. (Creator), Armitage, P. (Creator), Makin, S. (Creator), Touyz, R. M. (Creator), Wardlaw, J. (Creator), Thrippleton, M. (Creator), Sakka, E. (Creator), Escudero Rodriguez, J. (Creator) & Heye, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2966, https://www.preprints.org/manuscript/202010.0200/v1
Dataset
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Magnetisation transfer saturation (MTsat) processing
York, B. (Creator), Thrippleton, M. (Creator) & Waldman, A. (Creator), Edinburgh DataShare, 17 Dec 2020
DOI: 10.7488/ds/2965
Dataset
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Methods to quantify and visualize venules using structural magnetic resonance imaging scans
Jochems, A. (Creator), Blair, G. (Creator), Stringer, M. (Creator), Thrippleton, M. (Creator), Clancy, U. (Creator), Chappell, F. (Creator), Brown, R. (Creator), Jaime García, D. (Creator), Hamilton, O. (Creator), Morgan, A. (Creator), Marshall, I. (Creator), Hetherington, K. (Creator), Wiseman, S. (Creator), MacGillivray, T. (Creator), Valdes Hernandez, M. (Creator), Doubal, F. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 21 Jan 2020
DOI: 10.7488/ds/2755
Dataset
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MATLAB-based framework for simulating and processing BOLD CVR data
Thrippleton, M. (Creator) & Sleight, E. (Creator), Edinburgh DataShare, 3 Aug 2024
DOI: 10.7488/ds/3503
Dataset
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White Matter Hyperintensities Evolution Patterns 1 Year Post-lacunar Stroke and their association with post-stroke cognition
Thrippleton, M. (Creator), Valdes Hernandez, M. (Creator), Grimsley-Moore, T. (Creator), Sakka, E. (Creator), Chappell, F. (Creator), Armitage, P. (Creator), Makin, S. (Creator) & Wardlaw, J. (Creator), Edinburgh DataShare, 23 Jun 2021
DOI: 10.7488/ds/3063, https://doi.org/10.3389/fneur.2021.634460
Dataset