After his PhD at Imperial College London, Miguel worked at Manchester University, Centre for the History of Science, and the Spanish National Research Council (CSIC), Department of Science, Technology and Society. His research interests are in the history of contemporary biomedicine, with special emphasis on the transition between molecular biology and new forms of knowledge production at the fall of the 20^th century:  biotechnology, bioinformatics and genomics. He is now developing a five-year Chancellor's Fellowship in the Department of Science, Technology and Innovation Studies of the University of Edinburgh.

His research focuses on the history of agricultural biotechnology and the cloning of Dolly the sheep, and the development of concerted mapping and sequencing initiatives, with special attention to the science, politics and socio-economic expectations behind the human and other large-scale genome projects which proliferated in the 1980s and 90s. A paperback edition of his book Biology, Computing and the History of Molecular Sequencing: From Proteins to DNA was recently published by Palgrave-Macmillan. He previously worked as a journalist and is interested in science communication and public engagement.