Research output per year
Research output per year
Personal profile
My research in a nutshell
I am an analytical chemist and biomedical scientist, using bioanalytical innovations to measure small molecules by chromatography and mass spectrometry. With particular expertise in quantitative steroid analysis, including glucocorticoids, estrogens and androgens in human and pre-clinical settings. Investigations into other small molecule measurements including drugs, other lipid like molecules and metabolites of endogenous and exogenous molecules are also part of my research. I run the Mass Spectrometry Core, part of the Edinburgh Clinical Research Facility.
Collaborative Activity
Collaborators outside of University of Edinburgh include
Education/Academic qualification
Chemistry, Doctor of Science, Erythrocyte Oxidative Stress; Focus on Hormone Replacement Therapy, University of Strathclyde
1 Sept 1998 → 1 Jul 2002
Award Date: 20 Jan 2003
External positions
Vice Treasurer, Core Technologies for Life Sciences
5 Jan 2023 → …
Treasurer, Scottish Metabolomics Network
1 Aug 2022 → …
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Proof of concept for a superior therapeutic index of corticosterone compared with hydrocortisone in patients with congenital adrenal hyperplasia
Kyle, C., Boyle, L., Nixon, M., Homer, N. Z. M., Simpson, J., Rutter, A., Ramage, L. E., Kelman, A., Freel, E. M., Andrew, R., Walker, B. R. & Stimson, R., 15 Nov 2024, In: European Journal of Endocrinology. 191, 6, p. 535–544Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis.
Higgins, B., Simitsidellis, I., Zheng, X., Collins, F., Homer, N. Z. M., Denham, S. G., Simpson, J. P., Millar, M., Boswell, L., Lee, H. Y., Kim, Y. G., Park, K. H., Park, L. C., Sweeney, P. J., Feraille, G., Taddei, A., Chagras, D., Alvaraz, T., Webster, S. P., Horne, A., & 2 others, 2 Aug 2024, In: eLIFE.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet: Abcc1 influences metabolic response to obesity.
Villalobos, E., Miguelez-Crespo, A., Morgan, R. A., Ivatt, L., Paul, M., Simpson, J. P., Homer, N. Z. Z. M., Kurian, D., Aguilar, J., Kline, R., Wishart, T., Morton, N., Stimson, R. H., Andrew, R., Walker, B. R. & Nixon, M., 1 Aug 2024, In: Journal of Endocrinology. 262, 2, p. 1-13 13 p., e240024.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Deletion of Hsd11b1 suppresses caloric restriction-induced bone marrow adiposity in male but not female mice
Lovdel, A., Suchacki, K. J., Roberts, F., Sulston, R. J., Wallace, R. J., Thomas, B. J., Bell, R. M. B., Pruñonosa Cervera, I., Macpherson, G. J., Morton, N. M., Homer, N. Z. M., Chapman, K. E. & Cawthorn, W. P., 24 Jun 2024, In: Journal of Endocrinology . 262, 2, e240072.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A practical approach to supported liquid extraction and measurement of 18 steroids in plasma and serum by targeted liquid chromatography tandem mass spectrometry
Denham, S. G., Simpson, J. P., Diez, F., Lee, P., Kyle, C., Morgan, R. & Homer, N. Z., Jun 2024, In: MethodsX. 12, p. 1-13 13 p., 102728.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Prizes
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Fellow Institute of Biomedical Sciences
Homer, Natalie (Recipient), 1 Oct 2023
Prize: Election to learned society
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Unravelling challenges to lifelong health by next generation Mass Spectrometry
Homer, N., Andrew, R., Morgan, R., Nixon, M., Reynolds, R., Stimson, R., Denham, S., Meddle, S. & Simpson, J.
1/10/24 → 30/09/25
Project: Research
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Assessing Feasibility of Saliva Samples to Profile Progesterone for Infertility Treatment Monitoring
4/03/24 → 28/02/25
Project: Research
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Assessing feasibility of saliva samples to profile progesterone for infertility treatment monitoring
4/03/24 → 28/02/25
Project: Research
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The transition from a sexual to a parental brain via nest building
Meddle, S., Andrew, R., Homer, N. & Homer, N.
1/12/23 → 30/11/26
Project: Research
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High Resolution Mass Spectrometry to enhance hormonal profiling across the lifespan
Andrew, R., Homer, N. & Reynolds, R.
1/08/21 → 31/07/22
Project: Research
Datasets
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JCM-2373852 Caco-2-HepaRG Cell Culture Media Optimisation & LC-MSMS analysis of APAP metabolism during Caco-2 cell culture
Homer, N. (Creator) & Morgan, K. (Creator), Edinburgh DataShare, 9 Jun 2023
DOI: 10.7488/ds/7471
Dataset
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Data from: Higher insulin resistance & adiposity in post-menopausal women with breast cancer treated with aromatase inhibitors
Gibb, F. W. (Creator), Dixon, M. (Creator), Clarke, C. (Creator), Homer, N. (Creator), Faqehi, A. M. M. (Creator), Andrew, R. (Creator) & Walker, B. R. (Creator), Dryad, 3 May 2019
DOI: 10.5061/dryad.2n054k4, https://datadryad.org/stash/dataset/doi:10.5061/dryad.2n054k4
Dataset
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Development of a UPLC-MS/MS method for the simultaneous analysis of AT7519 and acetaminophen in a mouse model of acute inflammation
Rossi, A. (Creator), Simpson, J. (Creator), Cartwright, J. (Creator) & Homer, N. (Creator), Edinburgh DataShare, 19 May 2023
DOI: 10.7488/ds/7453
Dataset
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Analysis of AT7519 and acetaminophen in a mouse model of acute inflammation by LC-MS/MS
Homer, N. (Creator), Cartwright, J. (Creator), Rossi, A. (Creator) & Simpson, J. (Creator), Edinburgh DataShare, 27 Feb 2024
DOI: 10.7488/ds/7686
Dataset
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Dataset: Deletion of Hsd11b1 suppresses caloric-restriction-induced bone marrow adiposity in male but not female mice_v2024_05_07
Chapman, K. (Creator), Suchacki, K. (Creator), Cawthorn, W. (Creator), Lovdel, A. (Creator), Thomas, B. (Creator), Roberts, F. (Creator) & Homer, N. (Creator), Edinburgh DataShare, 8 May 2024
DOI: 10.7488/ds/7730
Dataset