Neil Henderson

PROF

Personal Chair of Tissue Repair and Regeneration, Deanery of Clinical Sciences
Centre for Inflammation Research

Phone0131 242 6688
EmailNeil.Henderson@ed.ac.uk

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55 Article
11 Literature review
7 Meeting abstract
3 Review article
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Fibrosis: from mechanisms to medicines
Henderson, N. C., Rieder, F. & Wynn, T. A., 25 Nov 2020, In: Nature. 587, 7835, p. 555-566
Research output: Contribution to journal › Article › peer-review
Decoding myofibroblast origins in human kidney fibrosis
Kuppe, C., Ibrahim, M. M., Kranz, J., Zhang, X., Ziegler, S., Perales-patón, J., Jansen, J., Reimer, K. C., Smith, J. R., Dobie, R., Wilson-Kanamori, J. R., Halder, M., Xu, Y., Kabgani, N., Kaesler, N., Klaus, M., Gernhold, L., Puelles, V. G., Huber, T. B., Boor, P. & 9 others, Menzel, S., Hoogenboezem, R. M., Bindels, E. M. J., Steffens, J., Floege, J., Schneider, R. K., Saez-rodriguez, J., Henderson, N. C. & Kramann, R., 14 Jan 2021, In: Nature. 589, 7841, p. 281–286
Research output: Contribution to journal › Article › peer-review
Single- cell technologies in hepatology: new insights into liver biology and disease pathogenesis
Ramachandran, P., Matchett, K., Dobie, R., Wilson, J. & Henderson, N. C., 1 Jun 2020, In: Nature Reviews Gastroenterology and Hepatology.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
Resolving the fibrotic niche of human liver cirrhosis at single-cell level
Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., Taylor, R. S., Efremova, M., Vento-Tormo, R., Carragher, N. O., Kendall, T. J., Fallowfield, J. A., Harrison, E. M., Mole, D. J., Wigmore, S. J., Newsome, P. N. & 8 others, Weston, C. J., Iredale, J. P., Tacke, F., Pollard, J. W., Ponting, C. P., Marioni, J. C., Teichmann, S. A. & Henderson, N. C., 21 Nov 2019, In: Nature. 575, 7783, p. 512–518
Research output: Contribution to journal › Article › peer-review

Open Access
File
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis
Dobie, R., Wilson-Kanamori, J. R., Henderson, B., Smith, J., Matchett, K., Portman, J., Wallenborg, K., Picelli, S., Zagórska, A., Pendem, S. V., Hudson, T. E., Wu, M. M., Budas, G. R., Breckenridge, D. G., Harrison, E., Mole, D. J., Wigmore, S. J., Ramachandran, P., Ponting, C. P., Teichmann, S. A. & 2 others, Marioni, J. C. & Henderson, N. C., 12 Nov 2019, In: Cell Reports. 29, 7, p. 1832-1847.e8
Research output: Contribution to journal › Article › peer-review

Open Access
File

11 Active
18 Finished

Using spatial transcriptomics to elucidate the key cellular and molecular mechanisms regulating human liver regeneration
Matchett, K., Henderson, N. & Wigmore, S.
UK-based charities
1/09/20 → 31/08/21
Project: Research
Exploitation of the Response to Injury in Saphenous Vein Bypass Grafts
Baker, A., Hadoke, P., Henderson, N., Newby, D. & Rodor, J.
UK-based charities
1/04/20 → 31/03/25
Project: Research
Defining the oxidative stress-related mechanisms by which activation of the transcription factor Nrf2 arrests and resolves liver fibrosis
Henderson, N., Kendall, T. & Walsh, T.
MRC
1/04/20 → 31/12/24
Project: Research
ITEN Project
Henderson, N.
Non-EU industry, commerce and public corporations
1/02/20 → 31/01/23
Project: Research
Investigation of antifibrotic targets in human liver fibrosis using a single cell transcriptomics approach
Henderson, N., Fallowfield, J. & Wigmore, S.
UK-based charities
1/02/20 → 31/01/25
Project: Research

Resolving the fibrotic niche of human liver cirrhosis at single-cell level - Seurat RData object
Ramachandran, P. (Creator), Henderson, N. (Creator) & Wilson-Kanamori, J. R. (Creator), Edinburgh DataShare, 25 Oct 2019
DOI: 10.7488/ds/2637, https://www.nature.com/articles/s41586-019-1631-3 and one more link, https://www.biorxiv.org/content/10.1101/766113v1 (show fewer)
Dataset
Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis - Seurat objects
Dobie, R. (Creator), Wilson-Kanamori, J. R. (Creator) & Henderson, N. (Creator), Edinburgh DataShare, 12 Feb 2020
DOI: 10.7488/ds/2769, https://www.sciencedirect.com/science/article/pii/S2211124719313245
Dataset

Neil Henderson develops treatment for muscle scarring linked to heart failure
Neil Henderson
25/10/17
6 items of Media coverage
Press/Media: Research
Neil Henderson to lead research which aims to combat liver disease in children
Neil Henderson
17/06/14
1 item of Media coverage
Press/Media: Research
Dr Neil Henderson’s insight into scar tissue could help reduce the need for organ transplants
Neil Henderson
11/11/13
5 items of Media coverage
Press/Media: Research