Research output per year
Research output per year
Personal profile
My research in a nutshell
I am interested in how our genes predipose us to, or protect us from, the adverse metabolic effects of the modern "obesogenic lifestyle". I believe understanding the intrinsic mechanisms that allow some people to remain lean, healthy and age successfully despite the "onslaught of plenty" will illuminate new therapeutic avenues for metabolic dysfunction and its associated diseases.
Education/Academic qualification
Biochemistry, Doctor of Philosophy (PhD), Integrated control of pancreatic beta cell function
Award Date: 1 Dec 1999
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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene
Kentistou, K., Luan, J., Wittemans, L. B. L., Hambly, C., Klaric, L., Kutalik, Z., Speakman, J. R., Wareham, N. J., Kendall, T. J., Langenberg, C., Wilson, J. F., Joshi, P. K. & Morton, N. M., 19 Jan 2023, In: Nature Communications.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness
Šimon, M., Mikec, Š., Morton, N. M., Atanur, S. S., Konc, J., Horvat, S. & Kunej, T., 21 Nov 2022, In: Mammalian Genome.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes
Hughes, R. E., Elliott, R. J. R., Li, X., Munro, A. F., Makda, A., Carter, R. N., Morton, N. M., Fujihara, K., Clemons, N. J., Fitzgerald, R., O’neill, J. R., Hupp, T. & Carragher, N. O., 13 Jun 2022, (E-pub ahead of print) In: Acs chemical biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
Suchacki, K., Thomas, B. J., Fyfe, C., Tavares, A. A. S., Sulston, R., Lovdel, A., Woodward, H. J., Han, X., Mattiucci, D., Brain, E. J., Alcaide-Corral, C. J., Gray, G. A., Whitfield, P. D., Stimson, R. H., Morton, N. M., Johnstone, A. M. & Cawthorn, W. P., 22 Feb 2022, bioRxiv, (bioRxiv).Research output: Working paper › Preprint
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Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
Czapiewski, R., Batrakou, D. G., de las Heras, J., Nicholas Carter, R., Sivakumar, A., Sliwinska, M., Dixon, C., Webb, S., Lattanzi, G., Morton, N. M. & Schirmer, E. C., 13 Jan 2022, In: Nature Communications. 13, 1, 18 p., 321.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Dissecting thermogenesis by brown adipose tissue and skeletal muscle in lean and obese subjects
1/04/22 → 31/03/25
Project: Research
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A facility for high resolution synchronised quantification of in vivo metabolism and behaviour
Semple, R., Morgan, R. & Morton, N.
1/10/21 → 30/09/26
Project: Research
Datasets
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TST knockout liver proteome iTRAQ and persulfidome
Morton, N. (Creator), PRIDE database hosted by European Bioinformatics Institute, EBI, 9 Nov 2021
https://www.ebi.ac.uk/pride/archive and one more link, https://www.ebi.ac.uk/pride/archive/projects/PXD028909 (show fewer)
Dataset
Press / Media
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New drugs are needed to combat diabetes, says Prof Nicholas Morton
20/06/16
1 item of Media coverage
Press/Media: Expert Comment
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Researchers identify a protein which effects whether people are apple or pear-shaped
9/03/11
15 items of Media coverage
Press/Media: Research
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Lean gene discovery by Prof Nik Morton could lead to new type 2 diabetes therapies
7/06/16
4 items of Media coverage
Press/Media: Research
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Dr Nik Morton's finds body fat stored around the torso is unhealthy
12/04/13
1 item of Media coverage
Press/Media: Research
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Genes may play a role in how we store fat, says Dr Nik Morton
9/09/11
28 items of Media coverage
Press/Media: Research