Search results

  • 2024

    X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

    Scholz, M., Horn, K., Pott, J., Wuttke, M., Kühnapfel, A., Nasr, M. K., Kirsten, H., Li, Y., Hoppmann, A., Gorski, M., Ghasemi, S., Li, M., Tin, A., Chai, J-F., Cocca, M., Wang, J., Nutile, T., Akiyama, M., Åsvold, B. O., Bansal, N., & 139 othersBiggs, M. L., Boutin, T., Brenner, H., Brumpton, B., Burkhardt, R., Cai, J., Campbell, A., Campbell, H., Chalmers, J., Chasman, D. I., Chee, M. L., Chee, M. L., Chen, X., Cheng, C-Y., Cifkova, R., Daviglus, M., Delgado, G., Dittrich, K., Edwards, T. L., Endlich, K., Michael Gaziano, J., Giri, A., Giulianini, F., Gordon, S. D., Gudbjartsson, D. F., Hallan, S., Hamet, P., Hartman, C. A., Hayward, C., Heid, I. M., Hellwege, J. N., Holleczek, B., Holm, H., Hutri-Kähönen, N., Hveem, K., Isermann, B., Jonas, J. B., Joshi, P. K., Kamatani, Y., Kanai, M., Kastarinen, M., Khor, C. C., Kiess, W., Kleber, M. E., Körner, A., Kovacs, P., Krajcoviechova, A., Kramer, H., Krämer, B. K., Kuokkanen, M., Kähönen, M., Lange, L. A., Lash, J. P., Lehtimäki, T., Li, H., Lin, B. M., Liu, J., Loeffler, M., Lyytikäinen, L-P., Magnusson, P. K. E., Martin, N. G., Matsuda, K., Milaneschi, Y., Mishra, P. P., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Mychaleckyj, J. C., März, W., Nauck, M., Nikus, K., Nolte, I. M., Noordam, R., Okada, Y., Olafsson, I., Oldehinkel, A. J., Penninx, B. W. J. H., Perola, M., Pirastu, N., Polasek, O., Porteous, D. J., Poulain, T., Psaty, B. M., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rasheed, H., Reilly, D. F., Rice, K. M., Richmond, A., Ridker, P. M., Rotter, J. I., Rudan, I., Sabanayagam, C., Salomaa, V., Schneiderman, N., Schöttker, B., Sims, M., Snieder, H., Stark, K. J., Stefansson, K., Stocker, H., Stumvoll, M., Sulem, P., Sveinbjornsson, G., Svensson, P. O., Tai, E-S., Taylor, K. D., Tayo, B. O., Teren, A., Tham, Y-C., Thiery, J., Thio, C. H. L., Thomas, L. F., Tremblay, J., Tönjes, A., van der Most, P. J., Vitart, V., Völker, U., Wang, Y. X., Wang, C., Wei, W. B., Whitfield, J. B., Wild, S. H., Wilson, J. F., Winkler, T. W., Wong, T-Y., Woodward, M., Sim, X., Chu, A. Y., Feitosa, M. F., Thorsteinsdottir, U., Hung, A. M., Teumer, A., Franceschini, N., Parsa, A., Köttgen, A., Schlosser, P. & Pattaro, C., 18 Jan 2024, In: Nature Communications. 15, 1, p. 586

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  • 2023

    Patterns of item nonresponse behaviour to survey questionnaires are systematic and associated with genetic loci

    Mignogna, G., Carey, C. E., Wedow, R., Baya, N., Cordioli, M., Pirastu, N., Bellocco, R., Malerbi, K. F., Nivard, M. G., Neale, B. M., Walters, R. K. & Ganna, A., 29 Jun 2023, (E-pub ahead of print) In: Nature Human Behaviour.

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  • An atlas of genetic scores to predict multi-omic traits

    Xu, Y., Ritchie, S. C., Liang, Y., Timmers, P. R. H. J., Pietzner, M., Lannelongue, L., Lambert, S. A., Tahir, U. A., May-Wilson, S., Foguet, C., Johansson, Å., Surendran, P., Nath, A. P., Persyn, E., Peters, J. E., Oliver-Williams, C., Deng, S., Prins, B., Luan, J., Bomba, L., & 17 othersSoranzo, N., Di Angelantonio, E., Pirastu, N., Tai, E. S., van Dam, R. M., Parkinson, H., Davenport, E. E., Paul, D. S., Yau, C., Gerszten, R. E., Mälarstig, A., Danesh, J., Sim, X., Langenberg, C., Wilson, J. F., Butterworth, A. S. & Inouye, M., 29 Mar 2023, In: Nature. 616, 7955, p. 123-131 9 p.

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  • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

    China Kadoorie Biobank Collaborative Group & Cox, S. R., 13 Mar 2023, In: Nature Genetics. 55, 3, p. 410-422 13 p.

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  • Mendelian randomisation identifies priority groups for prophylactic EBV vaccination

    Muckian, M. D., Wilson, J. F., Taylor, G. S., Stagg, H. R. & Pirastu, N., 3 Feb 2023, In: BMC Infectious Diseases. 23, 1, p. 65 65.

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  • 2022

    Genome-wide Association Study of Liking for Several Types of Physical Activity in the UK Biobank and Two Replication Cohorts

    Klimentidis, Y. C., Newell, M., van der Zee, M. D., Bland, V. L., May-Wilson, S., Arani, G., Menni, C., Mangino, M., Arora, A., Raichlen, D. A., Alexander, G. E., Wilson, J. F., Boomsma, D. I., Hottenga, J-J., de Geus, E. J. C. & Pirastu, N., 1 Aug 2022, In: Medicine & Science in Sports & Exercise. 54, 8, p. 1252-1260

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  • Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    LifeLines Cohort Study, 13 Jun 2022, In: Communications Biology. 5, 1, p. 580 580.

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  • Using genetic variation to disentangle the complex relationship between food intake and health outcomes

    Pirastu, N., McDonnell, C., Grzeszkowiak, E. J., Mounier, N., Imamura, F., Merino, J., Day, F. R., Zheng, J., Taba, N., Pina Concas, M., Repetto, L., Kentistou, K., Robino, A., Esko, T., Joshi, P. K., Fischer, K., Ong, K. K., Gaunt, T. R., Kutalik, Z., Perry, J. R. B., & 1 othersWilson, J. F., Jun 2022, In: PLoS Genetics. 18, 6, e1010162.

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  • Genetic Landscape of the ACE2 Coronavirus Receptor

    GenOMICC Consortium and the IMI-DIRECT Consortium, 3 May 2022, In: Circulation. 145, 18, p. 1398-1411

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  • Identification of genetic loci simultaneously associated with multiple cardiometabolic traits

    Wood, A. C., Arora, A., Newell, M., Bland, V. L., Zhou, J., Pirastu, N., Ordovas, J. M. & Klimentidis, Y. C., 1 Apr 2022, In: Nutrition, Metabolism & Cardiovascular Diseases. 32, 4, p. 1027-1034

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  • Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait

    Rannikmäe, K., Rawlik, K., Ferguson, A. C., Avramidis, N., Jiang, M., Pirastu, N., Shen, X., Davidson, E., Woodfield, R., Malik, R., Dichgans, M., Tenesa, A. & Sudlow, C., 2 Feb 2022, In: Frontiers in Neurology. 12, 787107.

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  • 2021

    Mendelian Randomization Identifies the Potential Causal Impact of Dietary Patterns on Circulating Blood Metabolites

    Taba, N., Valge, H-K., Metspalu, A., Esko, T., Wilson, J. F., Fischer, K. & Pirastu, N., 1 Nov 2021, In: Frontiers in Genetics. 12, p. 738265

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  • Variants associated with HHIP expression have sexdifferential effects on lung function

    Fawcett, K. A., Obeidat, M., Melbourne, C., Shrine, N., Guyatt, A. L., John, C., Luan, J., Richmond, A., Moksnes, M. R., Granell, R., Weiss, S., Imboden, M., May-Wilson, S., Hysi, P., Boutin, T. S., Portas, L., Flexeder, C., Harris, S. E., Wang, C. A., Lyytikäinen, L. P., & 55 othersPalviainen, T., Foong, R. E., Keidel, D., Minelli, C., Langenberg, C., Bossé, Y., Berge, M. V. D., Sin, D. D., Hao, K., Campbell, A., Porteous, D., Padmanabhan, S., Smith, B. H., Evans, D. M., Ring, S., Langhammer, A., Hveem, K., Willer, C., Ewert, R., Stubbe, B., Pirastu, N., Klaric, L., Joshi, P. K., Patasova, K., Massimo, M., Polasek, O., Starr, J. M., Karrasch, S., Strauch, K., Meitinger, T., Rudan, I., Rantanen, T., Pietiläinen, K., Kähönen, M., Raitakari, O. T., Hall, G. L., Sly, P. D., Pennell, C. E., Kaprio, J., Lehtimäki, T., Vitart, V., Deary, I. J., Jarvis, D., Wilson, J. F., Spector, T., Probst-Hensch, N., Wareham, N. J., Völzke, H., Henderson, J., Strachan, D. P., Brumpton, B. M., Hayward, C., Hall, I. P., Tobin, M. D. & Wain, L. V., 24 May 2021, In: Wellcome Open Research. 5, p. 1-20 20 p.

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  • Variants associated with HHIP expression have sex-differential effects on lung function

    Fawcett, K. A., Obeidat, M., Melbourne, C., Shrine, N., Guyatt, A. L., John, C., Luan, J., Richmond, A., Moksnes, M. R., Granell, R., Weiss, S., Imboden, M., May-wilson, S., Hysi, P., Boutin, T. S., Portas, L., Flexeder, C., Harris, S. E., Wang, C. A., Lyytikäinen, L., & 55 othersPalviainen, T., Foong, R. E., Keidel, D., Minelli, C., Langenberg, C., Bossé, Y., Van Den Berge, M., Sin, D. D., Hao, K., Campbell, A., Porteous, D., Padmanabhan, S., Smith, B. H., Evans, D. M., Ring, S., Langhammer, A., Hveem, K., Willer, C., Ewert, R., Stubbe, B., Pirastu, N., Klaric, L., Joshi, P. K., Patasova, K., Massimo, M., Polasek, O., Starr, J. M., Karrasch, S., Strauch, K., Meitinger, T., Rudan, I., Rantanen, T., Pietiläinen, K., Kähönen, M., Raitakari, O. T., Hall, G. L., Sly, P. D., Pennell, C. E., Kaprio, J., Lehtimäki, T., Vitart, V., Deary, I. J., Jarvis, D., Wilson, J. F., Spector, T., Probst-hensch, N., Wareham, N. J., Völzke, H., Henderson, J., Strachan, D. P., Brumpton, B. M., Hayward, C., Hall, I. P., Tobin, M. D. & Wain, L. V., 24 May 2021, In: Wellcome Open Research . 5, p. 111

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  • Genetic analyses identify widespread sex-differential participation bias

    Pirastu, N., Cordioli, M., Nandakumar, P., Mignogna, G., Abdellaoui, A., Hollis, B., Kanai, M., Rajagopal, V. M., Parolo, P. D. B., Baya, N., Carey, C. E., Karjalainen, J., Als, T. D., Zee, M. D. V. D., Day, F. R., Ong, K. K., Morisaki, T., Geus, E. D., Bellocco, R., Okada, Y., & 9 othersBørglum, A. D., Joshi, P., Auton, A., Hinds, D., Neale, B. M., Walters, R. K., Nivard, M. G., Perry, J. R. B. & Ganna, A., 22 May 2021, In: Nature Genetics. 53, p. 663 671 p., 53.

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  • 2020

    More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

    GCCR Group Author , 20 Jun 2020, (E-pub ahead of print) In: Chemical senses.

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  • 2019

    Coffee consumption and kidney function: A Mendelian randomisation study

    Kennedy, O. J., Pirastu, N., Poole, R., Fallowfield, J., Hayes, P., Grzeszkowiak, E. J., Taal, M. W., Wilson, J., Parkes, J. & Roderick, P., 11 Dec 2019, (E-pub ahead of print) In: American Journal of Kidney Diseases.

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  • Associations of autozygosity with a broad range of human phenotypes

    Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-gomez, C., Karlsson, R., Bao, Y., Bartz, T. M., & 416 othersBaumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., Van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., De Haan, H. G., Harris, S. E., Hofer, E., Huerta-chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., Van Der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., Van Der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., De Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M., Chen, G., Chen, Y. I., Chen, Z., Chiu, Y., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., Van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., Van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K., Khor, C. C., De Kleijn, D. P. V., Koh, W., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I., Lee, W., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P., Moreno-macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., De Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., Van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., Van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-khayat, B., Sennblad, B., Van Setten, J., Sever, P. J., Sheu, W. H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., Van Den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., Van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., Van Der Harst, P., Heng, C., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., Van Der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., Mccarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O’connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In: Nature Communications. 10, 1

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  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

    Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O’Connor, L. J., Prins, B., Nutile, T., Noce, D., Akiyama, M., & 208 othersCocca, M., Ghasemi, S., van der Most, P. J., Horn, K., Xu, Y., Fuchsberger, C., Sedaghat, S., Afaq, S., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boerwinkle, E., Bottinger, E. P., Boutin, T. S., Brumat, M., Burkhardt, R., Campana, E., Campbell, A., Campbell, H., Carroll, R. J., Catamo, E., Chambers, J. C., Ciullo, M., Concas, M. P., Coresh, J., Corre, T., Cusi, D., Sala, C. F., de Borst, M. H., De Grandi, A., de Mutsert, R., de Vries, A. P. J., Delgado, G., Demirkan, A., Devuyst, O., Dittrich, K., Eckardt, K-U., Ehret, G., Endlich, K., Evans, M. K., Gansevoort, R. T., Gasparini, P., Giedraitis, V., Gieger, C., Girotto, G., Gögele, M., Gordon, S. D., Gudbjartsson, D. F., Gudnason, V., German Chronic Kidney Disease Study, Haller, T., Hamet, P., Harris, T. B., Hayward, C., Hicks, A. A., Hofer, E., Holm, H., Huang, W., Hutri-Kähönen, N., Hwang, S-J., Arfan Ikram, M., Lewis, R. M., Ingelsson, E., Jakobsdottir, J., Jonsdottir, I., Jonsson, H., Joshi, P. K., Josyula, N. S., Jung, B., Kähönen, M., Kamatani, Y., Kanai, M., Kerr, S. M., Kiess, W., Kleber, M. E., Koenig, W., Kooner, J. S., Körner, A., Kovacs, P., Krämer, B. K., Kronenberg, F., Kubo, M., Kühnel, B., La Bianca, M., Lange, L. A., Lehne, B., Lehtimäki, T., LifeLines Cohort Study, Liu, J., Loeffler, M., Loos, R. J. F., Lyytikäinen, L-P., Mägi, R., Mahajan, A., Martin, N. G., März, W., Mascalzoni, D., Matsuda, K., Meisinger, C., Meitinger, T., Metspalu, A., Milaneschi, Y., V. A. Million Veteran Program, O'Donnell, C. J., Wilson, O. D., Gaziano, J. M., Mishra, P. P., Mohlke, K. L., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Müller-Nurasyid, M., Nadkarni, G. N., Nalls, M. A., Nauck, M., Nikus, K., Ning, B., Nolte, I. M., Noordam, R., O'Connell, J. R., Olafsson, I., Padmanabhan, S., Penninx, B. W. J. H., Perls, T., Peters, A., Pirastu, M., Pirastu, N., Pistis, G., Polasek, O., Ponte, B., Porteous, D. J., Poulain, T., Preuss, M. H., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rettig, R., Rheinberger, M., Rice, K. M., Rizzi, F., Robino, A., Rudan, I., Krajcoviechova, A., Cifkova, R., Rueedi, R., Ruggiero, D., Ryan, K. A., Saba, Y., Salvi, E., Schmidt, H., Schmidt, R., Shaffer, C. M., Smith, A. V., Smith, B. H., Spracklen, C. N., Strauch, K., Stumvoll, M., Sulem, P., Tajuddin, S. M., Teren, A., Thiery, J., Thio, C. H. L., Thorsteinsdottir, U., Toniolo, D., Tönjes, A., Tremblay, J., Uitterlinden, A. G., Vaccargiu, S., van der Harst, P., van Duijn, C. M., Verweij, N., Völker, U., Vollenweider, P., Waeber, G., Waldenberger, M., Whitfield, J. B., Wild, S. H., Wilson, J. F., Yang, Q., Zhang, W., Zonderman, A. B., Bochud, M., Wilson, J. G., Pendergrass, S. A., Ho, K., Parsa, A., Pramstaller, P. P., Psaty, B. M., Böger, C. A., Snieder, H., Butterworth, A. S., Okada, Y., Edwards, T. L., Stefansson, K., Susztak, K., Scholz, M., Heid, I. M., Hung, A. M., Teumer, A., Pattaro, C., Woodward, O. M., Vitart, V. & Köttgen, A., Oct 2019, In: Nature Genetics. 51, 10, p. 1459–1474

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  • A catalog of genetic loci associated with kidney function from analyses of a million individuals

    Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J. F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M., Ghasemi, S., & 199 othersXu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T., Brenner, H., Brumat, M., Campbell, A., Campbell, H., Hayward, C., Joshi, P. K., Kerr, S., LifeLines Cohort Study, Lim, S-C., Lind, L., Lindgren, C. M., Liu, J., Liu, J., Loeffler, M., Loos, R. J. F., Lucae, S., Lukas, M. A., Lyytikäinen, L-P., Mägi, R., Magnusson, P. K. E., Mahajan, A., Martin, N. G., Martins, J., März, W., Mascalzoni, D., Matsuda, K., Meisinger, C., Meitinger, T., Melander, O., Metspalu, A., Mikaelsdottir, E. K., Milaneschi, Y., Miliku, K., Mishra, P. P., V. A. Million Veteran Program, Mohlke, K. L., Montgomery, G. W., Mychaleckyj, J. C., Nadkarni, G. N., Nalls, M. A., Nauck, M., Nikus, K., Ning, B., Nolte, I. M., Noordam, R., O’Connell, J. R., O'Donoghue, M. L., Olafsson, I., Oldehinkel, A. J., Orho-Melander, M., Ouwehand, W. H., Padmanabhan, S., Palmer, N. D., Palsson, R., Penninx, B. W. J. H., Perls, T., Perola, M., Pirastu, M., Pirastu, N., Pistis, G., Podgornaia, A. I., Polasek, O., Ponte, B., Porteous, D. J., Poulain, T., Pramstaller, P. P., Preuss, M. H., Prins, B. P., Province, M. A., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rettig, R., Rheinberger, M., Rice, K. M., Ridker, P. M., Rivadeneira, F., Rizzi, F., Roberts, D. J., Robino, A., Rossing, P., Rudan, I., Rueedi, R., Ruggiero, D., Ryan, K. A., Saba, Y., Sabanayagam, C., Salomaa, V., Salvi, E., Saum, K-U., Schmidt, H., Schmidt, R., Schöttker, B., Schulz, C-A., Schupf, N., Shaffer, C. M., Shi, Y., Smith, A. V., Smith, B. H., Soranzo, N., Spracklen, C. N., Strauch, K., Stringham, H. M., Stumvoll, M., Svensson, P. O., Szymczak, S., Tai, E-S., Tajuddin, S. M., Tan, N. Y. Q., Taylor, K. D., Teren, A., Tham, Y-C., Thiery, J., Thio, C. H. L., Thomsen, H., Thorleifsson, G., Toniolo, D., Tönjes, A., Tremblay, J., Tzoulaki, I., Uitterlinden, A. G., Vaccargiu, S., van Dam, R. M., van der Harst, P., van Duijn, C. M., Velez Edwards, D. R., Verweij, N., Vogelezang, S., Völker, U., Vollenweider, P., Waeber, G., Waldenberger, M., Wallentin, L., Wang, Y. X., Wang, C., Waterworth, D. M., Wei, W. B., White, H., Whitfield, J. B., Wild, S. H., Wilson, J. F., Wojczynski, M. K., Wong, C., Wong, T-Y., Xu, L., Yang, Q., Yasuda, M., Yerges-Armstrong, L. M., Zhang, W., Zonderman, A. B., Rotter, J. I., Bochud, M., Psaty, B. M., Vitart, V., Wilson, J. G., Dehghan, A., Parsa, A., Chasman, D. I., Ho, K., Morris, A. P., Devuyst, O., Akilesh, S., Pendergrass, S. A., Sim, X., Böger, C. A., Okada, Y., Edwards, T. L., Snieder, H., Stefansson, K., Hung, A. M., Heid, I. M., Scholz, M., Teumer, A., Köttgen, A. & Pattaro, C., Jun 2019, In: Nature Genetics. 51, 6, p. 957-972 16 p.

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  • 2018

    A genome-wide association study identifies an association between variants in EFCAB4B gene and periodontal disease in an Italian isolated population

    Bevilacqua, L., Navarra, C. O., Pirastu, N., Lenarda, R. D., Gasparini, P. & Robino, A., 4 Oct 2018, (E-pub ahead of print) In: Journal of Periodontal Research.

    Research output: Contribution to journalArticlepeer-review

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  • Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

    Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T. & Wilson, J. F., 29 Jun 2018, In: Nature Communications. 9, 1, p. 2536

    Research output: Contribution to journalArticle

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  • Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'

    Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T. & Wilson, J. F., 29 Jun 2018, In: Nature Communications. 9, 1, p. 2538

    Research output: Contribution to journalArticlepeer-review

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  • 2017

    GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

    Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T. & Wilson, J. F., 17 Nov 2017, In: Nature Communications. 8, 1584.

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

    Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., Mcdaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C., & 93 othersBartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J-J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In: Nature Communications. 8, 13 p., 910.

    Research output: Contribution to journalArticlepeer-review

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  • Exploring influences on food choice in a large population sample: The Italian Taste project

    Monteleone, E., Spinelli, S., Dinnella, C., Endrizzi, I., Laureati, M., Pagliarini, E., Sinesio, F., Gasperi, F., Torri, L., Aprea, E., Bailetti, L. I., Bendini, A., Braghieri, A., Cattaneo, C., Cliceri, D., Condelli, N., Cravero, M. C., Del Caro, A., Di Monaco, R., Drago, S., & 17 othersFavotto, S., Fusi, R., Galassi, L., Toschi, T. G., Garavaldi, A., Gasparini, P., Gatti, E., Masi, C., Mazzaglia, A., Moneta, E., Piasentier, E., Piochi, M., Pirastu, N., Predieri, S., Robino, A., Russo, F. & Tesini, F., Jul 2017, In: Food Quality and Preference. 59, p. 123-140 18 p.

    Research output: Contribution to journalArticlepeer-review

  • 2016

    KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

    Schumann, G., Liu, C., O'Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., Segura Lepe, M., Akira, S., Barbieri, C., Baumeister, S., Cauchi, S., Clarke, T-K., Enroth, S., Fischer, K., Hällfors, J., Harris, S. E., & 107 othersHieber, S., Hofer, E., Hottenga, J-J., Johansson, Å., Joshi, P. K., Kaartinen, N., Laitinen, J., Lemaitre, R., Loukola, A., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Mbarek, H., Milaneschi, Y., Moayyeri, A., Mukamal, K., Nelson, C., Nettleton, J., Partinen, E., Rawal, R., Robino, A., Rose, L., Sala, C., Satoh, T., Schmidt, R., Schraut, K., Scott, R., Smith, A. V., Starr, J. M., Teumer, A., Trompet, S., Uitterlinden, A. G., Venturini, C., Vergnaud, A-C., Verweij, N., Vitart, V., Vuckovic, D., Wedenoja, J., Yengo, L., Yu, B., Zhang, W., Zhao, J. H., Boomsma, D. I., Chambers, J., Chasman, D. I., Daniela, T., de Geus, E., Deary, I., Eriksson, J. G., Esko, T., Eulenburg, V., Franco, O. H., Froguel, P., Gieger, C., Grabe, H. J., Gudnason, V., Gyllensten, U., Harris, T. B., Hartikainen, A-L., Heath, A. C., Hocking, L., Hofman, A., Huth, C., Jarvelin, M-R., Jukema, J. W., Kaprio, J., Kooner, J. S., Kutalik, Z., Lahti, J., Langenberg, C., Lehtimäki, T., Liu, Y., Madden, P. A. F., Martin, N., Morrison, A., Penninx, B., Pirastu, N., Psaty, B., Raitakari, O., Ridker, P., Rose, R., Rotter, J. I., Samani, N. J., Schmidt, H., Spector, T. D., Stott, D., Strachan, D., Tzoulaki, I., van der Harst, P., van Duijn, C. M., Marques-Vidal, P., Vollenweider, P., Wareham, N. J., Whitfield, J. B., Wilson, J., Wolffenbuttel, B., Bakalkin, G., Evangelou, E., Liu, Y., Rice, K. M., Desrivières, S., Kliewer, S. A., Mangelsdorf, D. J., Müller, C. P., Levy, D. & Elliott, P., 13 Dec 2016, In: Proceedings of the National Academy of Sciences (PNAS).

    Research output: Contribution to journalArticlepeer-review

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  • Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption

    Pirastu, N., Kooyman, M., Robino, A., Van Der Spek, A., Navarini, L., Amin, N., Karssen, L. C., Van Duijn, C. M. & Gasparini, P., 25 Aug 2016, In: Scientific Reports. 6, 31590.

    Research output: Contribution to journalArticlepeer-review

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  • A reference panel of 64,976 haplotypes for genotype imputation

    Mccarthy, S., Das, S., Kretzschmar, W., Delaneau, O., Wood, A. R., Teumer, A., Kang, H. M., Fuchsberger, C., Danecek, P., Sharp, K., Luo, Y., Sidore, C., Kwong, A., Timpson, N., Koskinen, S., Vrieze, S., Scott, L. J., Zhang, H., Mahajan, A., Veldink, J., & 91 othersPeters, U., Pato, C., Van Duijn, C. M., Gillies, C. E., Gandin, I., Mezzavilla, M., Gilly, A., Cocca, M., Traglia, M., Angius, A., Barrett, J. C., Boomsma, D., Branham, K., Breen, G., Brummett, C. M., Busonero, F., Campbell, H., Chan, A., Chen, S., Chew, E., Collins, F. S., Corbin, L. J., Smith, G. D., Dedoussis, G., Dorr, M., Farmaki, A., Ferrucci, L., Forer, L., Fraser, R. M., Gabriel, S., Levy, S., Groop, L., Harrison, T., Hattersley, A., Holmen, O. L., Hveem, K., Kretzler, M., Lee, J. C., Mcgue, M., Meitinger, T., Melzer, D., Min, J. L., Mohlke, K. L., Vincent, J. B., Nauck, M., Nickerson, D., Palotie, A., Pato, M., Pirastu, N., Mcinnis, M., Richards, J. B., Sala, C., Salomaa, V., Schlessinger, D., Schoenherr, S., Slagboom, P. E., Small, K., Spector, T., Stambolian, D., Tuke, M., Tuomilehto, J., Van Den Berg, L. H., Van Rheenen, W., Volker, U., Wijmenga, C., Toniolo, D., Zeggini, E., Gasparini, P., Sampson, M. G., Wilson, J. F., Frayling, T., De Bakker, P. I. W., Swertz, M. A., Mccarroll, S., Kooperberg, C., Dekker, A., Altshuler, D., Willer, C., Iacono, W., Ripatti, S., Soranzo, N., Walter, K., Swaroop, A., Cucca, F., Anderson, C. A., Myers, R. M., Boehnke, M., Mccarthy, M. I., Durbin, R., Abecasis, G. & Marchini, J., 22 Aug 2016, (E-pub ahead of print) In: Nature Genetics. 48, 10, p. 1279-1283

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  • A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings

    Pirastu, N., Kooyman, M., Traglia, M., Robino, A., Willems, S. M., Pistis, G., Amin, N., Sala, C., Karssen, L. C., Van Duijn, C., Toniolo, D. & Gasparini, P., 1 Jun 2016, In: Reviews in Endocrine and Metabolic Disorders. 17, 2, p. 209-219

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association study identifies 74 loci associated with educational attainment

    LifeLines Cohort Study, 26 May 2016, In: Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journalArticlepeer-review

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  • 2015

    Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Day, F. R., Ruth, K. S., Thompson, D. J., Lunetta, K. L., Pervjakova, N., Chasman, D. I., Stolk, L., Finucane, H. K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A. D., Elks, C. E., Franceschini, N., He, C., Altmaier, E., Brody, J. A., Franke, L. L., Huffman, J. E., Keller, M. F., & 32 othersMcArdle, P. F., Nutile, T., Porcu, E., Robino, A., Rose, L. M., Schick, U. M., Smith, J. A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J-J., Mangino, M., Smith, A. V., Boutin, T. S., Campbell, A., Campbell, H., Figueroa, J., Pirastu, N., Pirie, A., Polasek, O., Porteous, D., Rudan, I., Wilson, J. F., Wright, A. F., Hayward, C., PRACTICAL Consortium & Tomlinson, I., Nov 2015, In: Nature Genetics. 47, 11, p. 1294-303 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Food Preference Patterns in a UK Twin Cohort

    Pallister, T., Sharafi, M., Lachance, G., Pirastu, N., Mohney, R. P., MacGregor, A., Feskens, E. J. M., Duffy, V., Spector, T. D. & Menni, C., 28 Sept 2015, (E-pub ahead of print) In: Twin Research and Human Genetics. 18, 6, p. 793-805 13 p.

    Research output: Contribution to journalArticlepeer-review

  • Polymorphisms in sweet taste genes (TAS1R2 and GLUT2), sweet liking, and dental caries prevalence in an adult Italian population

    Robino, A., Bevilacqua, L., Pirastu, N., Situlin, R., Di Lenarda, R., Gasparini, P. & Navarra, C. O., 13 Aug 2015, In: Genes & Nutrition. 10, 5, 9 p., 34.

    Research output: Contribution to journalArticlepeer-review

  • Multicohort analysis of the maternal age effect on recombination

    Martin, H. C., Christ, R., Hussin, J. G., O'Connell, J., Gordon, S., Mbarek, H., Hottenga, J-J., McAloney, K., Willemsen, G., Gasparini, P., Pirastu, N., Montgomery, G. W., Navarro, P., Soranzo, N., Toniolo, D., Vitart, V., Wilson, J. F., Marchini, J., Boomsma, D. I., Martin, N. G., & 1 othersDonnelly, P., 5 Aug 2015, In: Nature Communications. 6, p. 7846

    Research output: Contribution to journalArticlepeer-review

  • Uncovering the genetic basis for food preferences: the key to personalized nutrition plans?

    Pirastu, N. & Robino, A., 3 Aug 2015, In: Personalized medicine. 12, 4, p. 315-317 3 p.

    Research output: Contribution to journalEditorial

  • Directional dominance on stature and cognition in diverse human populations

    Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S., & 30 othersGuo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Campbell, A., Davies, G., Haley, C., Harris, S. E., Hastie, N. D., Kerr, S. M., Liewald, D. C. M., Navarro, P., Redmond, P., Wild, S., BioBank Japan Project, Morris, A. D., Starr, J. M., Deary, I. J., Pirastu, N., Wilson, J. G., Rudan, I., Porteous, D. J., Hayward, C., Wright, A. F., Campbell, H. & Wilson, J. F., 23 Jul 2015, In: Nature. 523, 7561, p. 459-462 4 p.

    Research output: Contribution to journalArticlepeer-review

  • Modulation of genetic associations with serum urate levels by body-mass-index in humans

    Huffman, J. E., Albrecht, E., Teumer, A., Mangino, M., Kapur, K., Johnson, T., Kutalik, Z., Pirastu, N., Pistis, G., Lopez, L. M., Haller, T., Salo, P., Goel, A., Li, M., Tanaka, T., Dehghan, A., Ruggiero, D., Malerba, G., Smith, A. V., Nolte, I. M., & 100 othersPortas, L., Phipps-Green, A., Boteva, L., Navarro, P., Johansson, A., Hicks, A. A., Polasek, O., Esko, T., Peden, J. F., Harris, S. E., Murgia, F., Wild, S. H., Tenesa, A., Tin, A., Mihailov, E., Grotevendt, A., Gislason, G. K., Coresh, J., D'Adamo, P., Ulivi, S., Vollenweider, P., Waeber, G., Campbell, S., Kolcic, I., Fisher, K., Viigimaa, M., Metter, J. E., Masciullo, C., Trabetti, E., Bombieri, C., Sorice, R., Döring, A., Reischl, E., Strauch, K., Hofman, A., Uitterlinden, A. G., Waldenberger, M., Wichmann, H-E., Davies, G., Gow, A. J., Dalbeth, N., Stamp, L., Smit, J. H., Kirin, M., Nagaraja, R., Nauck, M., Schurmann, C., Budde, K., Farrington, S. M., Theodoratou, E., Jula, A., Salomaa, V., Sala, C., Hengstenberg, C., Burnier, M., Mägi, R., Klopp, N., Kloiber, S., Schipf, S., Ripatti, S., Cabras, S., Soranzo, N., Homuth, G., Nutile, T., Munroe, P. B., Hastie, N., Campbell, H., Rudan, I., Cabrera, C., Haley, C., Franco, O. H., Merriman, T. R., Gudnason, V., Pirastu, M., Penninx, B. W., Snieder, H., Metspalu, A., Ciullo, M., Pramstaller, P. P., van Duijn, C. M., Ferrucci, L., Gambaro, G., Deary, I. J., Dunlop, M. G., Wilson, J. F., Gasparini, P., Gyllensten, U., Spector, T. D., Wright, A. F., Hayward, C., Watkins, H., Perola, M., Bochud, M., Kao, W. H. L., Caulfield, M., Toniolo, D., Völzke, H., Gieger, C., Köttgen, A. & Vitart, V., 26 Mar 2015, In: PLoS ONE. 10, 3, e0119752.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking

    Pirastu, N., Kooyman, M., Traglia, M., Robino, A., Willems, S. M., Pistis, G., Amin, N., Sala, C., Karssen, L. C., van Duijn, C. M., Toniolo, D. & Gasparini, P., 11 Mar 2015, In: European Journal of Human Genetics. 23, 12, p. 1717-1722 6 p.

    Research output: Contribution to journalArticlepeer-review

  • 2014

    Genetic landscape of populations along the Silk Road: admixture and migration patterns

    Mezzavilla, M., Vozzi, D., Pirastu, N., Girotto, G., d'Adamo, P., Gasparini, P. & Colonna, V., 5 Dec 2014, In: BMC Genetics. 15, 10 p., 131.

    Research output: Contribution to journalArticlepeer-review

  • Trans-ethnic meta-analysis of white blood cell phenotypes

    Keller, M. F., Reiner, A. P., Okada, Y., van Rooij, F. J. A., Johnson, A. D., Chen, M-H., Smith, A. V., Morris, A. P., Tanaka, T., Ferrucci, L., Zonderman, A. B., Lettre, G., Harris, T., Garcia, M., Bandinelli, S., Qayyum, R., Yanek, L. R., Becker, D. M., Becker, L. C., Kooperberg, C., & 29 othersKeating, B., Reis, J., Tang, H., Boerwinkle, E., Kamatani, Y., Matsuda, K., Kamatani, N., Nakamura, Y., Kubo, M., Liu, S., Dehghan, A., Felix, J. F., Hofman, A., Uitterlinden, A. G., van Duijn, C. M., Franco, O. H., Longo, D. L., Singleton, A. B., Psaty, B. M., Evans, M. K., Cupples, L. A., Rotter, J. I., O'Donnell, C. J., Takahashi, A., Wilson, J. G., Ganesh, S. K., Nalls, M. A., CHARGE Hematology & Pirastu, N., 5 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6944-60 17 p.

    Research output: Contribution to journalArticlepeer-review

  • Salt-inducible kinase 3, SIK3, is a new gene associated with hearing

    Wolber, L. E., Girotto, G., Buniello, A., Vuckovic, D., Pirastu, N., Lorente-Cánovas, B., Rudan, I., Hayward, C., Polasek, O., Ciullo, M., Mangino, M., Steves, C., Concas, M. P., Cocca, M., Spector, T. D., Gasparini, P., Steel, K. P. & Williams, F. M. K., 24 Jul 2014, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

    O'Connell, J., Gurdasani, D., Delaneau, O., Pirastu, N., Ulivi, S., Cocca, M., Traglia, M., Huang, J., Huffman, J. E., Rudan, I., McQuillan, R., Fraser, R. M., Campbell, H., Polasek, O., Asiki, G., Ekoru, K., Hayward, C., Wright, A. F., Vitart, V., Navarro, P., & 7 othersZagury, J-F., Wilson, J. F., Toniolo, D., Gasparini, P., Soranzo, N., Sandhu, M. S. & Marchini, J., 17 Apr 2014, In: PLoS Genetics. 10, 4, 21 p., e1004234.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Association Analysis of Bitter Receptor Genes in Five Isolated Populations Identifies a Significant Correlation between TAS2R43 Variants and Coffee Liking

    Pirastu, N., Kooyman, M., Traglia, M., Robino, A., Willems, S. M., Pistis, G., d'Adamo, P., Amin, N., d'Eustacchio, A., Navarini, L., Sala, C., Karssen, L. C., van Duijn, C., Toniolo, D. & Gasparini, P., 19 Mar 2014, In: PLoS ONE. 9, 3, 7 p., 92065.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A Population-Based Approach to Study the Impact of PROP Perception on Food Liking in Populations along the Silk Road

    Robino, A., Mezzavilla, M., Pirastu, N., Dognini, M., Tepper, B. J. & Gasparini, P., 13 Mar 2014, In: PLoS ONE. 9, 3, 8 p., 91716.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

    Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M., & 98 othersPlia, M. G., Sala, C., Voelker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jorgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Raeikkoenen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., Den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Voelzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., 27 Feb 2014, In: PLoS Genetics. 10, 2, 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Exome analysis of HIV patients submitted to dendritic cells therapeutic vaccine reveals an association of CNOT1 gene with response to the treatment

    Moura, R., Pontillo, A., D'Adamo, P., Pirastu, N., Coelho, A. C. & Crovella, S., 10 Jan 2014, In: Journal of the International AIDS Society. 17, 5 p., 18938.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2013

    Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

    SUNLIGHT consortium & The GEFOS consortium, Sept 2013, In: PLoS Genetics. 9, 9, 13 p., e1003796.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
  • Genome Wide Association Analysis of a Founder Population Identified TAF3 as a Gene for MCHC in Humans

    CHARGE Consortium Hematology, Pistis, G., Okonkwo, S. U., Traglia, M., Sala, C., Shin, S-Y., Masciullo, C., Buetti, I., Massacane, R., Mangino, M., Thein, S-L., Spector, T. D., Ganesh, S., Pirastu, N., Gasparini, P., Soranzo, N., Camaschella, C., Hart, D., Green, M. R. & Toniolo, D., 31 Jul 2013, In: PLoS ONE. 8, 7, 8 p., 69206.

    Research output: Contribution to journalArticlepeer-review

  • Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci

    Paul, D. S., Albers, C. A., Rendon, A., Voss, K., Stephens, J., van der Harst, P., Chambers, J. C., Soranzo, N., Ouwehand, W. H., Deloukas, P., HaemGen Consortium & Pirastu, N., 9 Apr 2013, In: Genome Research. 23, 7, p. 1130-41 12 p.

    Research output: Contribution to journalArticlepeer-review