Research output per year
Research output per year
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Dive into the research topics where Nikhil Hirani is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics
Quinn, T., Gaughan, E. E., Bruce, A., Antonelli, J., O'Connor, R. A., Li, F., McNamara, S., Koch, O., Mackintosh, C., Dockrell, D., Walsh, T., Blyth, K. G., Church, C., Schwarze, J., Boz, C., Valanciute, A., Burgess, M., Emanuel, P., Mills, B., Rinaldi, G. & 27 others, , 10 Feb 2022, In: EBioMedicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Evaluation of new or repurposed treatments for COVID-19: protocol for the phase 1b/2a DEFINE trial platform
Gaughan, E., Quinn, T., Bruce, A., Antonelli, J., Young, V., Mair, J., Akram, A., Hirani, N., Koch, O., Mackintosh, C., Norrie, J., Dear, J. W. & Dhaliwal, K., 15 Dec 2021, In: BMJ Open.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair
Mccowan, J., Fercoq, F., Kirkwood, P. M., T’jonck, W., Hegarty, L. M., Mawer, C. M., Cunningham, R., Mirchandani, A. S., Hoy, A., Humphries, D. C., Jones, G., Hansen, C. G., Hirani, N., Jenkins, S. J., Henri, S., Malissen, B., Walmsley, S. R., Dockrell, D. H., Saunders, P. T. K., Carlin, L. M. & 1 others, , 19 Nov 2021, In: Science Immunology. 6, 65Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS
Reyes, L., Sanchez Garcia, M. A., Morrison, T., Howden, A. J. M., Watts, E. R., Arienti, S., Sadiku, P., Coelho, P., Mirchandani, A. S., Zhang, A., Hope, D., Clark, S. K., Singleton, J., Johnston, S., Grecian, R., Poon, A. S., McNamara, S., Harper, I., Fourman, M. H., Brenes, A. J. & 14 others, , 25 Jun 2021, (E-pub ahead of print) Wellcome Open Research, (wellcome Open Research).Research output: Working paper
Open AccessFile -
Application of a high-content screening assay utilising primary human lung fibroblasts to identify antifibrotic drugs for rapid repurposing in COVID-19 patients
Marwick, J., Elliott, R., Longden, J., Makda, A., Hirani, N., Dhaliwal, K., Dawson, J. C. & Carragher, N. O., 2 Jun 2021, (E-pub ahead of print) In: Slas Discovery.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
- 15 Finished
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Modulation Of Fibrotic Pathways By Novel Inhibitors Of Galectin-3
Hirani, N., Henderson, N. & Mackinnon, A.
1/08/19 → 31/01/22
Project: Research
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Measurement Of TGF-beta Related Biomarkers In Bronchial Alveolar Lavage Fluid (BALF)
1/02/18 → 31/01/19
Project: Research
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Development of anti-galectin-3 antibodies for the treatment of Idiopathic Pulmonary Fibrosis (IPF)
Mackinnon, A. & Hirani, N.
1/09/17 → 30/11/18
Project: Research
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Mechanism of action characterization for a galectin-3 inhibitor as treatment for lung injury
Mackinnon, A., Henderson, N., Hirani, N. & Rossi, A.
1/09/15 → 31/08/19
Project: Research
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Datasets
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Datasets for Low-Cost High Sensitivity Pulsed Endomicroscopy to Visualize Tri-Color Optical Signatures
Mills, B. (Creator), Murray, I. (Creator), Marshall, A. (Creator), Craven, T. (Creator), Emanuel, P. (Creator), Choudhary, T. (Creator), Norberg, D. (Creator), Scholefield, E. (Creator), Akram, A. (Creator), Davie, A. (Creator), Hirani, N. (Creator), Bruce, A. (Creator), Moore, A. (Creator), Bradley, M. (Creator), Dhaliwal, K. (Creator) & Krstajic, N. (Creator), Edinburgh DataShare, 1 Jul 2018
DOI: 10.7488/ds/2355
Dataset
Press / Media
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Dr Nikhil Hirani collaborates in study into pulmonary fibrosis.
15/01/14
1 item of Media coverage
Press/Media: Research
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Dr Nik Hirani comments on newly available treatment for lung disease
13/08/13
1 item of Media coverage
Press/Media: Expert Comment
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Dr Nik Hirani discusses efforts to develop drugs to treat pulmonary fibrosis
27/06/14
1 item of Media coverage
Press/Media: Research