Research output per year
Research output per year
DR
The application of, and development of new, bioinformatics methods for the study of neurodevelopmental disorders.
In recent years, high-throughput genome sequencing and related technologies have led to a dramatic increase in the quantity of data available to biologists, and require new computational methods to analyse. I am interested in the application of these techniques to the study of neurodevelopmental disorders, such as Intellectual Disabilities (ID) and Autism Spectrum Disorders (ASD), the rigorous assessment of the efficacy of such analyses, and the development of new techniques.
For more information on project areas, see Centre for Integrative Physiology profiles for Professor Peter Kind and Professor Giles Hardingham.
I originally trained in mathematics and theoretical physics, graduating with a 1st class Honours degree and Master's degree from the University of Cambridge, before completing a PhD in the Centre for Particle Theory at the University of Durham. Following a decade working in software engineering, I completed an MSc in Bioinformatics at Edinburgh in 2013, subsequently joining the University as a Postdoctoral Research Fellow.
Guest lectures in "Synaptic Function and Plasticity in Health and Disease" (Honours course, Centre for Integrative Physiology) and "Bioinformatics 2" (MSc course, School of Informatics).
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Working paper › Preprint
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
1/05/22 → 30/04/24
Project: Research
Spires-Jones, T. (Creator) & Dando, O. (Creator), EMBL's European Bioinformatics Institute, 2019
https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-7856
Dataset
Toombs, J. (Creator), King, D. (Creator), Holt, K. (Creator), Dando, O. (Creator) & Spires-Jones, T. (Creator), Edinburgh DataShare, 27 Oct 2022
DOI: 10.7488/ds/3777, https://www.medrxiv.org/content/10.1101/2022.05.04.22274679v1
Dataset
Catalano, S. M. (Creator), Dando, O. (Creator), Hamby, M. E. (Creator), Izzo, N. J. (Creator), Smith, C. (Creator), Spires-Jones, T. (Creator), Colom Cadena, M. (Creator), Toombs, J. (Creator), Simzer, E. M. (Creator), Tulloch, J. (Creator), Jackson, R. (Creator), Catterson, J. (Creator), Rose, J. (Creator), Waybright, L. (Creator), Caggiano, A. O. (Creator), Davies, C. (Creator), Hooley, M. (Creator), Dunnett, S. (Creator), Tempelaar, R. (Creator) & Tzioras, M. (Creator), Edinburgh DataShare, 9 Jan 2024
DOI: 10.7488/ds/7664, https://www.biorxiv.org/content/10.1101/2021.02.01.428238v2
Dataset
Spires-Jones, T. (Creator) & Dando, O. (Creator), Edinburgh DataShare, 13 Aug 2024
DOI: 10.7488/ds/7790, https://doi.org/10.1111/nan.13006
Dataset