Search results

  • 2011

    Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    DIAGRAM Consortium, GIANT Consortium, Morris, A., Rudan, I., Campbell, H. & Wilson, J., 2011, In: Diabetes . 60, 10, p. 2624-34 11 p.

    Research output: Contribution to journalArticlepeer-review

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  • 2010

    Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

    GIANT Consortium, Elks, C. E., Perry, J. R. B., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J-J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., & 31 othersMcArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, N. M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Navarro, P., Rudan, I., Wilson, J. F. & Wright, A. F., Dec 2010, In: Nature Genetics. 42, 12, p. 1077-85 9 p.

    Research output: Contribution to journalArticlepeer-review

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  • New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8

    Vitart, V., Bencić, G., Hayward, C., Skunca Herman, J., Huffman, J., Campbell, S., Bućan, K., Navarro, P., Gunjaca, G., Marin, J., Zgaga, L., Kolcić, I., Polasek, O., Kirin, M., Hastie, N. D., Wilson, J. F., Rudan, I., Campbell, H., Vatavuk, Z., Fleck, B., & 1 othersWright, A., 1 Nov 2010, In: Human Molecular Genetics. 19, 21, p. 4304-4311 8 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association analysis identifies multiple loci related to resting heart rate

    Eijgelsheim, M., Newton-Cheh, C., Sotoodehnia, N., de Bakker, P. I. W., Mueller, M., Morrison, A. C., Smith, A. V., Isaacs, A., Sanna, S., Doerr, M., Navarro, P., Fuchsberger, C., Nolte, I. M., de Geus, E. J. C., Estrada, K., Hwang, S-J., Bis, J. C., Rueckert, I-M., Alonso, A., Launer, L. J., & 54 othersHottenga, J. J., Rivadeneira, F., Noseworthy, P. A., Rice, K. M., Perz, S., Arking, D. E., Spector, T. D., Kors, J. A., Aulchenko, Y. S., Tarasov, K. V., Homuth, G., Wild, S. H., Marroni, F., Gieger, C., Licht, C. M., Prineas, R. J., Hofman, A., Rotter, J. I., Hicks, A. A., Ernst, F., Najjar, S. S., Wright, A. F., Peters, A., Fox, E. R., Oostra, B. A., Kroemer, H. K., Couper, D., Voelzke, H., Campbell, H., Meitinger, T., Uda, M., Witteman, J. C. M., Psaty, B. M., Wichmann, H-E., Harris, T. B., Kaeaeb, S., Siscovick, D. S., Jamshidi, Y., Uitterlinden, A. G., Folsom, A. R., Larson, M. G., Wilson, J. F., Penninx, B. W., Snieder, H., Pramstaller, P. P., van Duijn, C. M., Lakatta, E. G., Felix, S. B., Gudnason, V., Pfeufer, A., Heckbert, S. R., Stricker, B. H. C., Boerwinkle, E. & O'Donnell, C. J., Oct 2010, In: Human Molecular Genetics. 19, 19, p. 3885-3894 10 p.

    Research output: Contribution to journalArticlepeer-review

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  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    GIANT Consortium, MAGIC Investigators, Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., & 31 othersHofmann, O. M., Dupuis, J., Qi, L., Segre, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrom, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Morris, A., Rudan, I., Campbell, H. & Wilson, J. F., Jul 2010, In: Nature Genetics. 42, 7, p. 579-U155 13 p.

    Research output: Contribution to journalArticlepeer-review

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  • Genetic comparison of a Croatian isolate and CEPH European founders

    Navarro, P., Vitart, V., Hayward, C., Tenesa, A., Zgaga, L., Juricic, D., Polasek, O., Hastie, N. D., Rudan, I., Campbell, H., Wright, A. F., Haley, C. S. & Knott, S. A., Feb 2010, In: Genetic Epidemiology. 34, 2, p. 140-5 6 p.

    Research output: Contribution to journalArticlepeer-review

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  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    DIAGRAM Consortium, Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., & 31 othersHenneman, P., Grallert, H., Dehghan, A., Hottenga, J. J., Franklin, C. S., Navarro, P., Song, K., Goel, A., Perry, J. R. B., Egan, J. M., Lajunen, T., Grarup, N., Sparsø, T., Doney, A., Voight, B. F., Stringham, H. M., Li, M., Kanoni, S., Shrader, P., Cavalcanti-Proença, C., Kumari, M., Qi, L., Timpson, N. J., Hayward, C., Vitart, V., Wild, S. H., Morris, A., Rudan, I., Wright, A. F., Campbell, H. & Wilson, J. F., Feb 2010, In: Nature Genetics. 42, 2, p. 105-116 12 p.

    Research output: Contribution to journalArticlepeer-review

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  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P., & 287 othersGrallert, H., Dehghan, A., Hottenga, J. J., Franklin, C. S., Navarro, P., Song, K., Goel, A., Perry, J. R. B., Egan, J. M., Lajunen, T., Grarup, N., Sparsø, T., Doney, A., Voight, B. F., Stringham, H. M., Li, M., Kanoni, S., Shrader, P., Cavalcanti-Proença, C., Kumari, M., Qi, L., Timpson, N. J., Gieger, C., Zabena, C., Rocheleau, G., Ingelsson, E., An, P., O'Connell, J., Luan, JA., Elliott, A., McCarroll, S. A., Payne, F., Roccasecca, R. M., Pattou, F., Sethupathy, P., Ardlie, K., Ariyurek, Y., Balkau, B., Barter, P., Beilby, J. P., Ben-Shlomo, Y., Benediktsson, R., Bennett, A. J., Bergmann, S., Bochud, M., Boerwinkle, E., Bonnefond, A., Bonnycastle, L. L., Borch-Johnsen, K., Böttcher, Y., Brunner, E., Bumpstead, S. J., Charpentier, G., Chen, Y. D. I., Chines, P., Clarke, R., Coin, L. J. M., Cooper, M. N., Cornelis, M., Crawford, G., Crisponi, L., Day, I. N. M., De Geus, E. J. C., Delplanque, J., Dina, C., Erdos, M. R., Fedson, A. C., Fischer-Rosinsky, A., Forouhi, N. G., Fox, C. S., Frants, R., Franzosi, M. G., Galan, P., Goodarzi, M. O., Graessler, J., Groves, C. J., Grundy, S., Gwilliam, R., Gyllensten, U., Hadjadj, S., Hallmans, G., Hammond, N., Han, X., Hartikainen, A. L., Hassanali, N., Hayward, C., Heath, S. C., Hercberg, S., Herder, C., Hicks, A. A., Hillman, D. R., Hingorani, A. D., Hofman, A., Hui, J., Hung, J., Isomaa, B., Johnson, P. R. V., Jørgensen, T., Jula, A., Kaakinen, M., Kaprio, J., Kesaniemi, Y. A., Kivimaki, M., Knight, B., Koskinen, S., Kovacs, P., Kyvik, K. O., Lathrop, G. M., Lawlor, D. A., Le Bacquer, O., Lecoeur, C., Li, Y., Lyssenko, V., Mahley, R., Mangino, M., Manning, A. K., Martínez-Larrad, M. T., McAteer, J. B., McCulloch, L. J., McPherson, R., Meisinger, C., Melzer, D., Meyre, D., Mitchell, B. D., Morken, M. A., Mukherjee, S., Naitza, S., Narisu, N., Neville, M. J., Oostra, B. A., Orr, M., Pakyz, R., Palmer, C. N. A., Paolisso, G., Pattaro, C., Pearson, D., Peden, J. F., Pedersen, N. L., Perola, M., Pfeiffer, A. F. H., Pichler, I., Polasek, O., Posthuma, D., Potter, S. C., Pouta, A., Province, M. A., Psaty, B. M., Rathmann, W., Rayner, N. W., Rice, K., Ripatti, S., Rivadeneira, F., Roden, M., Rolandsson, O., Sandbaek, A., Sandhu, M., Sanna, S., Sayer, A. A., Scheet, P., Scott, L. J., Seedorf, U., Sharp, S. J., Shields, B., Sigursson, G., Sijbrands, E. J. G., Silveira, A., Simpson, L., Singleton, A., Smith, N. L., Sovio, U., Swift, A., Syddall, H., Syvänen, A. C., Tanaka, T., Thorand, B., Tichet, J., Tönjes, A., Tuomi, T., Uitterlinden, A. G., Van Dijk, K. W., Van Hoek, M., Varma, D., Visvikis-Siest, S., Vitart, V., Vogelzangs, N., Waeber, G., Wagner, P. J., Walley, A., Walters, G. B., Ward, K. L., Watkins, H., Weedon, M. N., Wild, S. H., Willemsen, G., Witteman, J. C. M., Yarnell, J. W. G., Zeggini, E., Zelenika, D., Zethelius, B., Zhai, G., Zhao, J. H., Zillikens, M. C., Consortium, D., Consortium, G., Consortium, G. B., Borecki, I. B., Loos, R. J. F., Meneton, P., Magnusson, P. K. E., Nathan, D. M., Williams, G. H., Hattersley, A. T., Silander, K., Salomaa, V., Smith, G. D., Bornstein, S. R., Schwarz, P., Spranger, J., Karpe, F., Shuldiner, A. R., Cooper, C., Dedoussis, G. V., Serrano-Ríos, M., Morris, A. D., Lind, L., Palmer, L. J., Hu, F. B., Franks, P. W., Ebrahim, S., Marmot, M., Kao, W. H. L., Pankow, J. S., Sampson, M. J., Kuusisto, J., Laakso, M., Hansen, T., Pedersen, O., Pramstaller, P. P., Wichmann, H. E., Illig, T., Rudan, I., Wright, A. F., Stumvoll, M., Campbell, H., Wilson, J. F., Hamsten, A., Bergman, R. N., Buchanan, T. A., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Valle, T. T., Altshuler, D., Rotter, J. I., Siscovick, D. S., Penninx, B. W. J. H., Boomsma, D. I., Deloukas, P., Spector, T. D., Frayling, T. M., Ferrucci, L., Kong, A., Thorsteinsdottir, U., Stefansson, K., Van Duijn, C. M., Aulchenko, Y. S., Cao, A., Scuteri, A., Schlessinger, D., Uda, M., Ruokonen, A., Jarvelin, M. R., Waterworth, D. M., Vollenweider, P., Peltonen, L., Mooser, V., Abecasis, G. R., Wareham, N. J., Sladek, R., Froguel, P., Watanabe, R. M., Meigs, J. B., Groop, L., Boehnke, M., McCarthy, M. I., Florez, J. C. & Barroso, I., 17 Jan 2010, In: Nature Genetics. 42, 5

    Research output: Contribution to journalArticlepeer-review

  • Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

    MAGIC Investigators, 2010, In: Diabetes Care. 33, 12, p. 2684-91 8 p.

    Research output: Contribution to journalArticlepeer-review

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  • 2009

    Parental origin of sequence variants associated with complex diseases

    Voight, B. F., Raychaudhuri, S., Purcell, S., McCarroll, S. A., Segrè, A. V., Ardlie, K., Burtt, N. P., Crawford, G., Elliott, A. L., Green, T., Guiducci, C., Saxena, R., Daly, M. J., Florez, J. C., Altshuler, D., Meigs, J. B., Scott, L. J., Welch, R. P., Willer, C. J., Ganser, M., & 137 othersJackson, A. U., Stringham, H. M., Abecasis, G. R., Boehnke, M., Steinthorsdottir, V., Thorleifsson, G., Kong, A., Walters, G. B., Thorsteinsdottir, U., Stefansson, K., Dina, C., Proença, C., Cauchi, S., Froguel, P., Zeggini, E., Bumpstead, S., Payne, F., Smith, N., Barroso, I., Ferreira, T., Elliott, K. S., Lindgren, C. M., Prokopenko, I., Rayner, N. W., Robertson, N. R., Morris, A. P., McCarthy, M. I., Huth, C., Grallert, H., Gieger, C., Klopp, N., Meitinger, T., Petersen, A-K., Thorand, B., Wichmann, H-E., Illig, T., Aulchenko, Y. S., Amin, N., Witteman, J., Hofman, A., Van Duijn, C. M., McCulloch, L. J., Bennett, A. J., Groves, C. J., Hassanali, N., Owen, K. R., Gloyn, A. L., Wu, G., Stein, L. D., Langenberg, C., Griffin, S., Wareham, N. J., Hoffmann, O. M., Hide, W. A., Dupuis, J., Qi, L., Kraft, P., Sun, Q., Hunter, D., Hu, F. B., Cornelis, M., VanDam, R., Van Hoek, M., Van Herpt, T., Sijbrands, E., Uitterlinden, A., Navarro, P., Balkau, B., Benediktsson, R., Sigurdsson, G., Blagieva, R., Boehm, B. O., Boerwinkle, E., Bonnycastle, L. L., Chines, P. S., Erdos, M. R., Morken, M. A., Narisu, N., Swift, A. J., Boström, K. B., Bravenboer, B., Charpentier, G., Couper, D. J., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Fox, C. S., Franklin, C. S., Rudan, I., Grarup, N., Hadjadj, S., Thomas Sparsø, N. V., Campbell, H., Wilson, J. F., Hansen, T., Pedersen, O., Herder, C., Roden, M., Isomaa, B., Tuomi, T., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Kuusisto, J., Laakso, M., Lauritzen, T., Li, M., Lieverse, A., Lyssenko, V., Nilsson, P., Groop, L., Marre, M., Midthjell, K., Platou, C., Hveem, K., Perry, J. R. B., Shields, B. M., Weedon, M. N., Frayling, T. M., Hattersley, A. T., Rathmann, W., Strassburger, K., Rocheleau, G., Sladek, R., Sampson, M. J., Shrader, P., Tichet, J., Bergman, R. N., Collins, F. S., Gyllensten, U., Hitman, G. A., Mohlke, K. L., Pramstaller, P. P., Tuomilehto, J., Walker, M., Watanabe, R. M. & Pankow, J. S., 17 Dec 2009, In: Nature. 462, 7275, p. 868-874 7 p.

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide Association Analysis of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart Rate

    Eijgelsheim, M., Newton-Cheh, C., Sotoodehnia, N., de Bakker, P. I., Mueller, M., Morrison, A. C., Smith, A. V., Isaacs, A., Sanna, S., Doerr, M., Navarro, P., Fuchsberger, C., Wilson, J. F., Pramstaller, P. P., van Duijn, C. M., Lakatta, E. G., Felix, S. B., Gudnason, V., Pfeufer, A., Heckbert, S. R., & 3 othersStricker, B. H., Boerwinkle, E. & O'Donnell, C. J., 3 Nov 2009, In: Circulation. 120, 18, p. S579-S579 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  • Consequences of selection for improving production traits on the frequency of deleterious alleles for fitness

    Kearney, J. F., Navarro, P., Haley, C. S. & Villanueva, B., Mar 2009, In: Journal of Animal Science. 87, 3, p. 850-859 10 p.

    Research output: Contribution to journalArticlepeer-review

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  • 2007

    Haplotype Analysis and a Novel Allele-Sharing Method Refines a Chromosome 4p Locus Linked to Bipolar Affective Disorder

    Le Hellard, S., Lee, A. J., Underwood, S., Thomson, P. A., Morris, S. W., Torrance, H. S., Anderson, S. M., Adams, R. R., Navarro, P., Christoforou, A., Houlihan, L. M., Detera-Wadleigh, S., Owen, M. J., Asherson, P., Muir, W. J., Blackwood, D. H. R., Wray, N. R., Porteous, D. J. & Evans, K. L., 15 Mar 2007, In: Biological Psychiatry. 61, 6, p. 797-805 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Recent human effective population size estimated from linkage disequilibrium

    Tenesa, A., Navarro, P., Hayes, B. J., Duffy, D. L., Clarke, G. M., Goddard, M. E. & Visscher, P. M., 2007, In: Genome Research. 17, 4, p. 520-6 7 p.

    Research output: Contribution to journalArticlepeer-review

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  • 2006

    Genetic parameters for blood oxygen saturation, body weight and breast conformation in 4 meat-type chicken lines

    Navarro, P., Visscher, P. M., Chatziplis, D., Koerhuis, A. N. M. & Haley, C. S., Dec 2006, In: British Poultry Science. 47, 6, p. 659-670 12 p.

    Research output: Contribution to journalArticlepeer-review

  • Segregation analysis of blood oxygen saturation in broilers suggests a major gene influence on ascites

    Navarro, P., Visscher, P. M., Chatziplis, D., Koerhuis, A. N. M. & Haley, C. S., Dec 2006, In: British Poultry Science. 47, 6, p. 671-684 14 p.

    Research output: Contribution to journalArticlepeer-review

  • 2005

    Mapping of quantitative trait loci affecting organ weights and blood variables in a broiler layer cross

    Navarro, P., Visscher, P. M., Knott, S. A., Burt, D. W., Hocking, P. M. & Haley, C. S., Aug 2005, In: British Poultry Science. 46, 4, p. 430-442 13 p.

    Research output: Contribution to journalArticlepeer-review