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Personal profile

My research in a nutshell

The general interest of my laboratory is the cellular and molecular biology of the nervous system.  Our principle work focuses on degeneration of the motor system.  Previously we identified a gene mutation responsible for a rare form of Amyotrophic Lateral Sclerosis.  Using in vitro model systems and genetically modified animals we and our collaborators are exploiting this, and other genetic information to study more generally the processes of neurodegeneration. We also contribute to experiments on synaptic physiology, with particular focus on plasticity, intellectual disability and epilepsy.  And I have a long standing collaboration working regulated secretion from endothelial cells.

 

Teaching

I contribute lectures and tutorials for 2nd, 3rd and 4th year courses.  I’m deputy organizer for two 3rd year courses, Pharmacology 3 and Applied Pharmacology 3, and Exam Board Convener for Honours Pharmacology.

Year 2

Biomedical Sciences 2

Chemical Pharmacology 2

Year 3

Applied Pharmacology 3

Neuroscience 3

Pharmacology 3

Year 4

Honours core programmes

Honours Neuroscience

Honours Pharmacology

Honours electives

Developmental and Clinical Neuroscience

 

External positions

External Examiner, Lancaster University

2024 → 2027

External Examiner , University of Southampton

2022 → 2026

Research Themes and Networks

  • College of Medicine and Veterinary Medicine Research Themes

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Collaborations and top research areas from the last five years

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