Richard Smith

2022

Similar Rates of Deleterious Copy Number Variants in Early-Onset Psychosis and Autism Spectrum Disorder

Brownstein, C. A., Douard, E., Mollon, J., Smith, R., Hojlo, M. A., Das, A., Goldman, M., Garvey, E., Cabral, K., Li, J., Bowen, J., Rao, A. S., Genetti, C., Carroll, D., Knowles, E. E. M., Deaso, E., Agrawal, P. B., Beggs, A. H., D'Angelo, E. & Almasy, L. & 8 others, Alexander-Bloch, A., Saci, Z., Moreau, C. A., Huguet, G., Deo, A. J., Jacquemont, S., Glahn, D. C. & Gonzalez-Heydrich, J., 1 Nov 2022, In: The American Journal of Psychiatry. 179, p. 853-861

Research output: Contribution to journal › Article › peer-review

Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

ISARIC4C Investigators, Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., De Silva, T., Siggins, M. K., Drake, T. M., Thwaites, R. S., Abrams, S., Moore, S. C., Hardwick, H. E., Oosthuyzen, W., Harrison, E. M., Docherty, A. B., Openshaw, P. J. M., Baillie, J. K., Semple, M. G. & Ho, A., 1 May 2022, In: Open forum infectious diseases. 9, 5

Research output: Contribution to journal › Article › peer-review

Open Access

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Clinical presentation and assessment of older patients presenting with headache to emergency departments: A multicentre observational study

HEAD Study Group, Beck, S., Kinnear, F. B., Maree Kelly, A., Chu, K. H., Sen Kuan, W., Keijzers, G., Body, R., Karamercan, M. A., Klim, S., Wijeratne, T., Kamona, S., Graham, C. A., Roberts, T., Horner, D. & Laribi, S., 17 Mar 2022, In: Australasian Journal on Ageing. 41, 1, p. 126-137

Research output: Contribution to journal › Article › peer-review

2021

The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

COVID-19 Genomics UK (COG-UK) Consortium, ISARIC4C Investigators, de Silva, T. I., Liu, G., Lindsey, B. B., Dong, D., Moore, S. C., Hsu, N. S., Shah, D., Wellington, D., Mentzer, A. J., Angyal, A., Brown, R., Parker, M. D., Ying, Z., Yao, X., Turtle, L., Dunachie, S., Maini, M. K. & Ogg, G. & 4 others, Knight, J. C., Peng, Y., Rowland-Jones, S. L. & Dong, T., 19 Nov 2021, In: iScience. 24, 11, 103353.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Epidemiology, investigation, management, and outcome of headache in emergency departments (HEAD study)—A multinational observational study

HEAD Study Group, Kelly, A. M., Kuan, W. S., Chu, K., Kinnear, F. B., Keijzers, G., Karamercan, M., Klim, S., Wijeratne, T., Kamona, S., Graham, C. A., Body, R., Roberts, T., Horner, D. & Laribi, S., 1 Nov 2021, In: Headache: The Journal of Head and Face Pain. 61, 10, p. 1539-1552 14 p.

Research output: Contribution to journal › Article › peer-review

A prenylated dsRNA sensor protects against severe COVID-19

ISARIC4C Investigators, 28 Sept 2021, (E-pub ahead of print) In: Science (New York, N.Y.). eabj3624.

Research output: Contribution to journal › Article › peer-review

Open Access

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A 3D endometrial organotypic model simulating the acute inflammatory decidualisation initiation phase with epithelial induction of the key endometrial receptivity marker, integrin alpha V beta 3

Fraser, R., Smith, R. & Lin, C., 25 Aug 2021, In: Human Reproduction Open. 2021, 4, 13 p., hoab034.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

ISARIC investigators, 1 May 2021, In: The Lancet Respiratory Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2019

Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub-optimal

Kelly, A.-M., Van Meer, O., Keijzers, G., Motiejunaite, J., Jones, P., Body, R., Craig, S., Karamercan, M., Klim, S., Harjola, V.-P., Verschuren, F., Holdgate, A., Christ, M., Golea, A., Graham, C. A., Capsec, J., Barletta, C., Garcia-Castrillo, L., Kuan, W. S. & Laribi, S. & 138 others, McNulty, R., Tan, C., Cowell, D. L., Jain, N., Devillecourt, T., Forrester, A., Lee, K., Chalkley, D., Gillett, M., Lozzi, L., Asha, S., Duffy, M., Watkins, G., Stone, R., Rosengren, D., Thone, J., Martin, S., Orda, U., Thom, O., Kinnear, F., Eley, R., Ryan, A., Morel, D., May, C., Furyk, J., Thomson, G., Smith, S., Smith, R., Maclean, A., Grummisch, M., Meyer, A., Meek, R., Rosengarten, P., Chan, B., Haythorne, H., Archer, P., Wilson, K., Knott, J., Ritchie, P., Bryant, M., MacDonald, S., Lee, T., Mahlangu, M., Mountain, D., Rogers, I., Otto, T., Stuart, P., Bament, J., Brown, M., Greven-Garcia, R., Scott, M., Cheri, T., Nguyen, M., Wong, C.-P., Wong, T. W., Leung, L.-P., Man, C. K., Saiboon, I. M., Rahman, N. H., Lee, W. Y., Lee, F. C. Y., Russell, S., Lawoko, C., Laribi, S., Al Dandachi, G., Maignan, M., Hermand, D., Tessier, C., Roy, P.-M., Bucco, L., Duytsche, N., Garmilla, P., Carbone, G., Cosentini, R., Truță, S., Hrihorișan, N., Cimpoeșu, D., Rotaru, L., Petrică, A., Cojocaru, M., Nica, S., Tudoran, R., Vecerdi, C., Puticiu, M., Schönberger, T., Coolsma, C., Baggelaar, M., Fransen, N., van den Brand, C., Idzenga, D., Maas, M., Franssen, M., Mackaij-Staal, C., Schutte, L., de Kubber, M., Mignot-Evers, L., Penninga-Puister, U., Jansen, J., Kuijten, J., Bouwhuis, M., Reuben, A., Smith, J., Ramlakhan, S., Darwent, M., Gagg, J., Keating, L., Bongale, S., Hardy, E., Keep, J., Jarman, H., Crane, S., Lawal, O., Hassan, T., Corfield, A., Reed, M., Smolarsky, Y., Blaschke, S., Jerrentrup, C., Hohenstein, C., Brünnler, F., Ghuysen, A., Vranckx, M., Ergin, M., Dundar, Z. D., Altuncu, Y. A., Arziman, I., Avcil, M., Katirci, Y., Kokkonen, L., Valli, J., Kiljunen, M., Tolonen, J., Kaye, S., Mäkelä, J., Metsäniitty, J., Vaula, E., Duytsche, N. & Garmilla, P., 15 Apr 2019, In: Internal Medicine Journal.

Research output: Contribution to journal › Article › peer-review

2018

Arthroscopic treatment for cervical articular process joint osteochondrosis in a Thoroughbred horse

Tucker, R., Piercy, R. J., Dixon, J. J., Muir, C. F., Smith, K. C., Potter, K. E., Leaman, T. R. & Smith, R. K. W., 1 Feb 2018, In: Equine Veterinary Education. 30, 3, p. 116-121 6 p.

Research output: Contribution to journal › Article › peer-review

2017

The effect of Mycobacterium avium ssp. paratuberculosis infection on clinical mastitis occurrence in dairy cows

Rossi, G., Grohn, Y. T., Schukken, Y. H. & Smith, R. L., Sept 2017, In: Journal of Dairy Science. 100, 9, p. 7446-7454 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding

Smith, R. W. P., Anderson, R. C., Larralde, O., Smith, J. W. S., Gorgoni, B., Richardson, W. A., Malik, P., Graham, S. V. & Gray, N. K., 13 Jun 2017, In: Proceedings of the National Academy of Sciences (PNAS). 114, 24, p. 6310-6315

Research output: Contribution to journal › Article › peer-review

Open Access

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Evaluation of an enhanced cleaning and disinfection protocol in Salmonella contaminated pig holdings in the United Kingdom

Martelli, F., Lambert, M., Butt, P., Cheney, T., Tatone, F. A., Callaby, R., Rabie, A., Gosling, R. J., Fordon, S., Crocker, G., Davies, R. H. & Smith, R. P., 8 Jun 2017, In: PLoS ONE. 12, 6, 20 p., 0178897.

Research output: Contribution to journal › Article › peer-review

Open Access

File

RNA immunoprecipitation identifies novel targets of DAZL in human fetal ovary

Rosario, R., Smith, R., Adams, I. & Anderson, R., 1 Mar 2017, In: Molecular Human Reproduction.

Research output: Contribution to journal › Article › peer-review

Open Access

File

A modular route to boron doped PAHs by combining borylative cyclisation and electrophilic C-H borylation

Crossley, D. L., Kahan, R. J., Endres, S., Warner, A. J., Smith, R. A., Cid, J., Dunsford, J. J., Jones, J. E., Vitorica-Yrezabal, I. & Ingleson, M. J., 1 Jan 2017, In: Chemical Science. 8, 12, p. 7969-7977 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation

Brook, M., Tomlinson, G. H., Miles, K., Smith, R. W. P., Rossi, A. G., Hiemstra, P. S., van 't Wout, E. F. A., Dean, J. L. E., Gray, N. K., Lu, W. & Gray, M., 19 Apr 2016, In: Proceedings of the National Academy of Sciences (PNAS). 113, 16, p. 4350-4355 6 p.

Research output: Contribution to journal › Article › peer-review

File

2015

The Irinotecan metabolite SN38 is highly cytotoxic to germ cells in the mouse testis but has little ovotoxicity

Spears, N., Lopes, F., Nash, S., Smith, R. & Mitchell, R. T., Jun 2015, In: Human Reproduction. 30, p. 312-312 1 p.

Research output: Contribution to journal › Meeting abstract

Poly(A)-binding proteins and mRNA localization: Who rules the roost?

Gray, N., Hrabalkova, L., Scanlon, J. & Smith, R., 2015, In: Biochemical Society Transactions.

Research output: Contribution to journal › Literature review › peer-review

2014

Poly(A)-binding proteins are required for diverse biological processes in metazoans

Smith, R. W. P., Blee, T. K. P. & Gray, N. K., 1 Aug 2014, In: Biochemical Society Transactions. 42, 4, p. 1229-37 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2013

Urine c-peptide creatinine ratio can be used for home monitoring of islet transplant function

Oram, R. A., Brooks, A. M. S., Smith, R., Rutter, M. K., Johnson, P. R., Choudhary, P., Rosenthal, M., Forbes, S., McDonald, T. J., Hattersley, A. T. & Shaw, J. A. M., Mar 2013, In: Diabetic Medicine. 30, p. 87-87 1 p.

Research output: Contribution to journal › Meeting abstract

2012

A Molecular Doorstop Ensures a Trickle through Translational Repression

Brook, M., Smith, R. W. P. & Gray, N. K., 30 Mar 2012, In: Cell. 149, 1, p. 13-15 3 p.

Research output: Contribution to journal › Editorial › peer-review

2011

DAZAP1, an RNA-binding protein required for development and spermatogenesis, can regulate mRNA translation

Smith, R. W. P., Anderson, R. C., Smith, J. W. S., Brook, M., Richardson, W. A. & Gray, N. K., Jul 2011, In: RNA. 17, 7, p. 1282-1295 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2010

Regulation of poly(A) binding protein during herpes simplex virus infection

Larralde-Diaz, O. G., Smith, R. W. P., Malik, P., Graham, S. V. & Gray, N. K., Mar 2010, In: International Journal of Infectious Diseases. 14, p. E470-E470 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Poly(A)-binding protein (PABP): a common viral target

Smith, R. W. P. & Gray, N. K., 2010, In: Biochemical Journal. 426, 1, p. 1-12 12 p.

Research output: Contribution to journal › Literature review › peer-review

2009

Intensive versus Conventional Glucose Control in Critically Ill Patients

Study Coordinating Ctr, NICE Australia-New Zealand, NICE-SUGAR Study Investigators, Australia-New Zealand Site, Study Stat Ctr, Inde-pendent Data Safety, SUGAR North Amer Management Comm, Finfer, S., Blair, D., Bellomo, R., McArthur, C., Mitchell, I., Myburgh, J., Norton, R., Potter, J., Chittock, D., Dhingra, V., Foster, D., Cook, D., Dodek, P., Hebert, P., Henderson, W., Heyland, D., McDonald, E., Ronco, J. & Schweitzer, L. & 31 others, Peto, R., Sandercock, P., Sprung, C., Young, J. D., Su, S., Heritier, S., Li, Q., Bompoint, S., Billot, L., Crampton, L., Darcy, F., Jayne, K., Kumarasinghe, V., Little, L., McEvoy, S., MacMahon, S., Pandey, S., Ryan, S., Shukla, R., Vijayan, B., Atherton, S., Bell, J., Hadfield, L., Hourigan, C., McArthur, C., Newby, L., Simmonds, C., Buhr, H., Eccleston, M., Smith, R. & French, C., 26 Mar 2009, In: New England Journal of Medicine. 360, 13, p. 1283-1297 15 p.

Research output: Contribution to journal › Article › peer-review

2008

Regulation of translation initiation by herpesviruses

Smith, R. W. P., Graham, S. V. & Gray, N. K., Aug 2008, In: Biochemical Society Transactions. 36, Pt 4, p. 701-7 7 p.

Research output: Contribution to journal › Article › peer-review

2007

Implications of full compliance with the computed tomography scanning recommendations of the National Institute for Clinical Excellence and Scottish Intercollegiate Guidelines Network guidelines for the management of head injury

National Institute for Clinical Excellence and Scottish Intercollegiate Guidelines Network, Kerr, J., Beard, D., Smith, R., Gray, S., Robertson, C. E. & Dunn, L. T., 2007, In: European journal of emergency medicine : official journal of the European Society for Emergency Medicine. 14, 3, p. 147-50 4 p.

Research output: Contribution to journal › Article › peer-review

2006

Direct stimulation of translation by the multifunctional herpesvirus ICP27 protein

Larralde, O., Smith, R. W. P., Wilkie, G. S., Malik, P., Gray, N. K. & Clements, J. B., 2006, In: Journal of Virology. 80, 3, p. 1588-91 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2004

The epidemiology of posttraumatic adult respiratory distress syndrome

White, T. O., Jenkins, P. J., Smith, R. D., Cartlidge, C. & Robinson, C. M., 2004, In: Journal of Bone and Joint Surgery. 86-A, 11, p. 2366-76 11 p.

Research output: Contribution to journal › Article › peer-review

1998

A case-control study of true-positive versus false-negative cervical smears in women with cervical intraepithelial neoplasia (CIN) III

O'Sullivan, J. P., A'Hern, R. P., Chapman, P. A., Jenkins, L., Smith, R., al-Nafussi, A., Brett, M. T., Herbert, A., McKean, M. E. & Waddell, C. A., Jun 1998, In: Cytopathology. 9, 3, p. 155-61 7 p.

Research output: Contribution to journal › Article › peer-review

Noise Removal by Nonlinear Synapses

Van Rossum, M. C. W. & Smith, R. G., 1998, Computational Neuroscience: Trends in Research, 1998. Bower, J. M. (ed.). Boston, MA: Springer, p. 297-302 6 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1997

Autoregulation of the Escherichia coli replication initiator protein, DnaA, is indirect

Smith, R. W., McAteer, S. & Masters, M. D., Mar 1997, In: Molecular Microbiology. 23, 6, p. 1303-15

Research output: Contribution to journal › Article › peer-review

1996

Thermal stability of the three domains of streptokinase studied by circular dichroism and nuclear magnetic resonance

Conejero-Lara, F., Parrado, J., Azuaga, A. I., Smith, R. A., Ponting, C. P. & Dobson, C. M., Dec 1996, In: Protein Science. 5, 12, p. 2583-91 9 p.

Research output: Contribution to journal › Article › peer-review

The coupling between ftsZ transcription and initiation of DNA replication is not mediated by the DnaA-boxes upstream of ftsZ or by DnaA

Smith, R., McAteer, S. & Masters, M. D., Jul 1996, In: Molecular Microbiology. 21, 2, p. 361-72 12 p.

Research output: Contribution to journal › Article › peer-review

The domain organization of streptokinase: nuclear magnetic resonance, circular dichroism, and functional characterization of proteolytic fragments

Parrado, J., Conejero-Lara, F., Smith, R. A., Marshall, J. M., Ponting, C. P. & Dobson, C. M., Apr 1996, In: Protein Science. 5, 4, p. 693-704 12 p.

Research output: Contribution to journal › Article › peer-review

1985

Lack of congruence of S-carboxymethyl-L-cysteine sulphoxidation and debrisoquine 4-hydroxylation in a Caucasian population

Haley, C. S., Waring, R. H., Mitchell, S. C., Shah, R. R., Idle, J. R. & Smith, R. L., May 1985, In: Xenobiotica. 15, 5, p. 445-50 6 p.

Research output: Contribution to journal › Article › peer-review

1984

Genetic aspects of the polymodally distributed sulphoxidation of S-carboxymethyl-L-cysteine in man

Mitchell, S. C., Waring, R. H., Haley, C. S., Idle, J. R. & Smith, R. L., Oct 1984, In: British Journal of Clinical Pharmacology. 18, 4, p. 507-21 15 p.

Research output: Contribution to journal › Article › peer-review

Richard Smith

Research output

Search results