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  • Open Access
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  • Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

    Roberts, I., Shakur-Still, H., Afolabi, A., Akere, A., Arribas, M., Brenner, A., Chaudhri, R., Gilmore, I., Halligan, K., Hussain, I., Jairath, V., Javaid, K., Kayani, A., Lisman, T., Mansukhani, R., Mutti, M., Arif Nadeem, M., Pollok, R., Simmons, J., Soomro, M. & 443 others, Stanworth, S., Veitch, A., Hawkey, C., Cuzick, J., Henry, D., Metcalfe, C., Gray, R., Barkun, A., David, S., Devereaux, P., Brady, T., Coats, T., Edwards, P., Ker, K., Manno, D., Austin, E., Bal, K., Balogun, E., Barrow, C., Beaumont, D., Benyahia, M., Brooks, I., Cargill, M., Carrington, L., Frimley, L., Geer, A., Gilbert, D., Gilliam, C., Gil Onandia, J., Golfi, N., Hetherington, D., Howe, C., Hughes, C., I'anson, D., Jackson, R., Joshi, M., Kansagra, S., Kawahara, T., Kostrov, S., Miah, H., Ndungu, B., Needham, K., Outtandy, A., Pearson, D., Pepple, T., Prowse, D., Quashi, N., Quinn, A., Ramos, M., Ranopa, L., Reid, M., Roukas, C., Squires, C., Tanner, J., Thayne, A., Uddin, R., Fawole, B., Bello, F. A., Olayemi, O., Okunade, O., Adetayo, O., Khamis, H., Shukri Bin Jahit, M., Gogichaishvili, T., Mateescu, R. B., Adhikaree, A., Abdo, A. E., Zaher, M., Deasy, C., Alvarez Gregori, J., Wellsh, B., Lawton, L., Kamath, R., Barry, A., Carpio, R., Finney, K., Maguire, H., James, M., Coffey, F., Gough, C., Sawers, L., Thi, A-A., Burnett, C., Jacques, N., Murray, V., Jarman, H., Lambe, C., Rounding, S., Tucker, S., Al-Idari, R., Guest, S., Stoddard, E., Yeo, D., Bergin, C., Hardy, E., Thunder, J., Jhalli, P., Hartley, E., Jarvis, C., Swann, C., Reed, M., Gallagher, B., Grahamslaw, J., O'Brien, R., Harris, T., Bellhouse, G., Boulton, O., Skene, I., Stanley, A., Johnstone, J., Maguire, D., Thornton, S., Banks, M., Bercades, G., Marks, D., Ryu, J., Dowty, C., Pott, J., East, J., Bailey, A., Beer, S., Davies, S., Appelboam, A., Mackle, D., Small, J., Vorwerk, C., Atkins, R., Bradbury, I., Bryceland, C., McClelland, L., Thomas, M., Clayton, K., Michael, A., Haig, S., Al-Nahhas, S., Godfrey, T., Boger, P., Comer, R., Watkins, B., Afolabi, O., Afzal, S., Cowton, A., Everett, S., Fazakerley, R., Onoviran, F., Snook, J., Berry, J., Simpson, D., Keep, J., Cotton, H., Helyar, S., Rutter, M., Johnston, T., O'Rourke, L., Chan, L., Tambellini, J., Trodd, D., Shutt, J., Moreton, S., Oglesby, A., Boyle, A., Haeger, N., Hardwick, S., Kendall, J., Faulkner, B., Worner, R., Hearnshaw, S., Doona, M., Price, M., Hunter, L., Bell, M., Loureiro, V., Kehoe, A., Jefferey, A., Squire, R., Hartin, D., Bell, S., Newman, A., Gagg, J., Foot, J., Wakeford, S., May, G., Bartram, T., Cumpstay, P., Parker, L., Das, R., Pahary, S., Wright, G., Butt, G., Christmas, N., Wilson, S., Ashfaq, M., Chandler, L., Demetriou, C., Kaye, P., Carley, S., Brown, A., Jones, L., Whileman, A., Greenaway, J., Tregonning, J., Kuhrt, A., Goodacre, S., Jones, J., Owen, C., Mitra, A., Harper-Payne, A., Trudgill, N., Hayes, A., Butt, F., Clifford, G., Kinnon, A., Fowler, S., Pillay, K., Gidwani, S., McNair, A., Omer, O., de Weymarn, T., Amin, A., Martin, J., Mathieu, N., Barnes, S., Turvill, J., Sweeting, H., Draegebo, M., McNaught, M., Grocutt, M., Margalef, J., Humphrey, J., Jackson, R., Bellis, F., Hunt, J., Stevenson, A., Watson, N., Barden, S., Paterson, S., Macdonald, C., Hobday, D., Orugun, O., Allison, A., Dyer, T., McBride, S., Sawicki, W., Rayner, B., Flowerdew, L., Barbour, J., Klein, J., Hood, S., Palmer, N., de Wolff, J., Shenoy, A., Swallow, P., Srirajaskanthan, R., Arshad, S., Aslam, N., Bangash, A., Qamar, M., Zahoor, H., Arshad, S., ain Ghalib, Q., Hameed, T., Saif, T., Shafi, W., Ali, A., Khan, S., Muaaz, M., Taj, A., Ghafoor, A., Afridi, A., Ahmad, M., Aslam, M., Kumar, S., Ali, M., Bughio, U., Chang, A., Shaikh, S., Ahmad, S., Ali, Z., Waqar, M., Mushir, A., Sattar, S., Goraya, S., Aslam, S., Fatima, N., Noreen, S., Saleem, S., Rahman, F., Iqbal, N., Khalid, M., Riaz, U., Umar, M., Akhter, T., Khan, J., Misbah, N., Afzal, M., Kayani, M., Shah, S., Tarar, S., Khan, S., Iqbal, Y., Khan, E., Reki, M., Hussain, T., Iqbal, S., Khurram, M., Shafi, M., Shaikh, A., Ahmed, A., Kumar, A., Sachdev, P., Nasir, K. M., Chaudhry, Z. I., Zubair, M., Tayyab, G., Mushtaq, J., Nasir, M., Khan, A., Ali, A., Ali, S., Uddin, W., Ahmed, S., Kazmi, T., Channa, S., Aman, A., Shaikh, M., Rizvi, T., Hussain, A., Baqai, H. Z., Rasheed, Z., Khan, A., Irfan, A., Husain, A., Aslam, A., Yahya, K., Azhar, S., Ul Haq, M., Afzal, A., Imran, M., Saeed, I., Yusuf, A., Hassan, M., Marwat, M., Ishfaq, M., Bashir, T., Kumar, S., Yaqoob, S., Wahid, A., Fakoya, T., Oke, T., Tejan, E., Olaomi, O., Badejo, O., Nnaemaka, O., Ukwu, N., Arowolo, O., Aderounmu, A., Wuraola, F., Ugiagbe, R., Atiri, A., Eghaghe, E., Adekoya, A., Tade, A. O., Shonoiki, O., Olatoke, S., Raji, T., Ekwunife, C., Onyekpere, C., Ahmed, A., Muhammad, D., Odeghe, E., Lesi, O., Osueni, A., Samaila, A., Nahuche, A., Ajayi, A., Dongo, A., Ijoma, U., Adebanjo, A. T., Igetei, R., Yilkudi, M., Osisanya, K., Okeke, E. N., Enwere, O. O., Esmat, S., Ashoush, O., Naga, M., Nagy, F., Saiid, M., Shaker, A., Helmy, A., Saafan, S., Abdel Monem, M., Din, J., Azis, K., Brukan, M., Singh, S., Zakaria, A., Farid, S., Hashim, N., Mafauzy, M., Najmi, W., Amri, N., Yi, X., Hisyam, M., Ng, E., Ramli, Z., Yee Lim, S., Voon, K., Young Yam, S., Jahit, M., Joon, L., Melikidze, B., Kazaishvili, D., Grubelashvili, N., Mosidze, B., Tomadze, G., Megreladze, A., Oprita, R., Pestroiu Calescu, D., Chioncel, C., Ragea, A., Mateescu, B., Busuioc, B., Voiosu, A., Cotirlet, A., Pintilie, I., Jinga, M., Balaban, D., Tanău, M., Negreanu, L., Bataga, S., Priya, K., Baral, S., Anuj, K. C. A., Sah, V., Yadav, V., Abdo, A., Ahmed, D., Al Anazi, M., Al Balkhi, A., Álvarez Gregori, J., Fornieles Pérez, H. & Beqiri, A., 20 Jun 2020, In: The Lancet.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Ivacaftor Modifies Cystic Fibrosis Neutrophil Phenotype in Subjects with R117H Residual Function CFTR Mutations

    Hardisty, G. R., Law, S. M., Carter, S., Grogan, B., Singh, P. K., Mckone, E. F. & Gray, R. D., 27 Aug 2020, (E-pub ahead of print) In: European Respiratory Journal. p. 2002161

    Research output: Contribution to journalLetterpeer-review

    Open Access
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  • Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa

    McHugh, B. J., Wang, R., Li, H-N., Beaumont, P. E., Kells, R., Stevens, H., Young, L., Rossi, A. G., Gray, R. D., Dorin, J. R., Gwyer Findlay, E. L., Brough, D. & Davidson, D. J., 12 Apr 2019, In: PLoS Pathogens. 15, 4, e1007694.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
  • Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors

    Law, S. M., Stanfield, S. J., Hardisty, G. R., Dransfield, I., Campbell, C. J. & Gray, R. D., 6 Sep 2019, (E-pub ahead of print) In: Journal of Cystic Fibrosis.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File