Research output per year
Research output per year
- 1 - 50 out of 187 results
Search results
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2024
Review of methodology and re-analysis of lipidomic data focusing on Specialised Pro-Resolution Lipid Mediators (SPMs) in a human model of resolving inflammation.
Homer, N. Z. M., Andrew, R. & Gilroy, D. W., 23 Dec 2024, In: International Journal of Experimental Pathology.Research output: Contribution to journal › Article › peer-review
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Proof of concept for a superior therapeutic index of corticosterone compared with hydrocortisone in patients with congenital adrenal hyperplasia
Kyle, C., Boyle, L., Nixon, M., Homer, N. Z. M., Simpson, J., Rutter, A., Ramage, L. E., Kelman, A., Freel, E. M., Andrew, R., Walker, B. R. & Stimson, R., 15 Nov 2024, In: European Journal of Endocrinology. 191, 6, p. 535–544Research output: Contribution to journal › Article › peer-review
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Spatial lipidomic profiles of atherosclerotic plaques: A mass spectrometry imaging study
Ntshangase, S., Khan, S., Bezuidenhout, L., Gazárková, T., Kaczynski, J., Sellers, S., Rattray, N. JW., Newby, D. E., Hadoke, P. WF. & Andrew, R., 28 Sept 2024, In: Talanta. 282, 126954.Research output: Contribution to journal › Article › peer-review
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Preterm birth as a determinant of neurodevelopment and cognition in children (PRENCOG): protocol for an exposure-based cohort study in the United Kingdom
Boardman, J. P., Andrew, R., Bastin, M. E., Battersby, C., David Batty, G., Blesa Cabez, M., Cox, S. R., Hall, J., Ingledow, L., Marioni, R. E., Modi, N., Murphy, L., Quigley, A. J., Reynolds, R. M., Richardson, H., Stock, S. J., Thrippleton, M. J., Tsanas, A. & Whalley, H. C., 16 Sept 2024, In: BMJ Open. 14, 9, e085365.Research output: Contribution to journal › Article › peer-review
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ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet: Abcc1 influences metabolic response to obesity.
Villalobos, E., Miguelez-Crespo, A., Morgan, R. A., Ivatt, L., Paul, M., Simpson, J. P., Homer, N. Z. Z. M., Kurian, D., Aguilar, J., Kline, R., Wishart, T., Morton, N., Stimson, R. H., Andrew, R., Walker, B. R. & Nixon, M., 1 Aug 2024, In: Journal of Endocrinology. 262, 2, p. 1-13 13 p., e240024.Research output: Contribution to journal › Article › peer-review
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Pulmonary Hypertension and Anastrozole (PHANTOM): A Randomized, Double-Blind, Placebo-Controlled Trial
Kawut, S. M., Feng, R., Ellenberg, S. S., Zamanian, R., Bull, T., Chakinala, M., Mathai, S. C., Hemnes, A., Lin, G., Doyle, M., Andrew, R., Maclean, M., Stasinopoulos, I., Austin, E., Demichele, A., Shou, H., Minhas, J., Song, N., Moutchia, J. & Ventetuolo, C. E., 15 May 2024, In: American Journal of Respiratory and Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
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Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19
Devine, K., Russell, C. D., Rodriguez Blanco, G., Walker, B. R., Homer, N. Z. M., Denham, S. G., Simpson, J. P., Leavy, O. C., Elneima, O., McAuley, H. J. C., Shikotra, A., Singapuri, A., Sereno, M., Saunders, R. M., Harris, V. C., Houchen-Wolloff, L., Greening, N. J., Lone, N. I., Thorpe, M., Greenhalf, W., & 14 others, 17 Jan 2024, In: Clinical Endocrinology. 100, 4Research output: Contribution to journal › Article › peer-review
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Preterm birth as a determinant of neurodevelopment and cognition in children (PRENCOG): Protocol for an exposure-based cohort study in the UK
Boardman, J. P., Andrew, R., Bastin, M. E., Battersby, C., Batty, G. D., Cábez, M. B., Cox, S. R., Hall, J., Ingledow, L., Marioni, R. E., Modi, N., Murphy, L., Quigley, A. J., Reynolds, R. M., Richardson, H., Stock, S. J., Thrippleton, M. J., Tsanas, A. & Whalley, H. C., 2024, In: BMJ Open. 14, 9, e085365.Research output: Contribution to journal › Article › peer-review
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2023
Steroid profile in patients with breast cancer and in mice treated with mifepristone
Elía, A., Saldain, L., Lovisi, S., Martínez vazquez, P., Burruchaga, J., Lamb, C. A., Lüthy, I. A., Diez, F., Homer, N. Z. M., Andrew, R., Rojas, P. & Lanari, C., 13 Dec 2023, In: Endocrine-Related Cancer. 31, 2Research output: Contribution to journal › Article › peer-review
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5α-TETRAHYDROCORTICOSTERONE: A TOPICAL ANTI-INFLAMMATORY GLUCOCORTICOID WITH AN IMPROVED THERAPEUTIC INDEX IN A MURINE MODEL OF DERMATITIS
Livingstone, D. E. W., Sooy, K., Sykes, C., Webster, S. P., Walker, B. R. & Andrew, R., 21 Nov 2023, In: British Journal of Pharmacology. p. 1-12Research output: Contribution to journal › Article › peer-review
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Plasma cortisol linked gene networks in hepatic and adipose tissues implicate corticosteroid binding globulin in modulating tissue glucocorticoid action and cardiovascular risk
Bankier, S., Wang, L., Crawford, A., Morgan, R. A., Ruusalepp, A., Andrew, R., Björkegren, J. LM., Walker, B. R. & Michoel, T., 6 Sept 2023, In: Frontiers in Endocrinology.Research output: Contribution to journal › Article › peer-review
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Contribution of local regeneration of glucocorticoids to tissue steroid pools
Khan, S., Livingstone, D. E. W., Zielinska, A., Doig, C. L., Cobice, D. F., Esteves, C. L., Man, J. T. Y., Homer, N. Z. M., Seckl, J. R., Mackay, C. L., Webster, S. P., Lavery, G. G., Chapman, K. E., Walker, B. R. & Andrew, R., 1 Jun 2023, (E-pub ahead of print) In: Journal of Endocrinology .Research output: Contribution to journal › Article › peer-review
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Re-analysis of lipidomic data reveals Specialised Pro-Resolution Lipid Mediators (SPMs) to be lower than quantifiable limits of assay in a human model of resolving inflammation
Homer, N. ZM., Andrew, R. & Gilroy, D. W., 8 Mar 2023, bioRxiv.Research output: Working paper › Preprint
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11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis
Hadoke, P. W. F., Davidson, C., Miller, E., Dawson, J. C., Lee, M., Serrels, A., Webster, S. P., Muir, M., Aitken, S., Homer, N. Z. M., Andrew, R., Brunton, V. G. & Walker, B., Mar 2023, In: PLoS ONE. 18, 3, e0255709.Research output: Contribution to journal › Article › peer-review
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2022
The ATP-binding cassette proteins ABCB1 and ABCC1 as modulators of glucocorticoid action
Devine, K., Villalobos, E., Kyle, C., Andrew, R., Reynolds, R. M., Stimson, R. H., Nixon, M. & Walker, B. R., 11 Oct 2022, (E-pub ahead of print) In: Nature reviews endocrinology.Research output: Contribution to journal › Article › peer-review
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Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19 F-magnetic resonance spectroscopy
Naredo-Gonzalez, G., Upreti, R., Jansen, M. A., Semple, S., Sutcliffe, O. B., Marshall, I., Walker, B. R. & Andrew, R., 29 Sept 2022, In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
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Marked oestrous cycle-dependent regulation of rat arterial KV7.4 channels driven by GPER1
Baldwin, S. N., Forrester, E. A., Homer, N. Z. M., Andrew, R., Barrese, V., Stott, J. B., Isakson, B. E., Albert, A. P. & Greenwood, I. A., 9 Sept 2022, In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
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Mapping Endocrine Networks by Stable Isotope Tracing
Andrew, R. & Stimson, R. H., 19 Jul 2022, (E-pub ahead of print) In: Current Opinion in Endocrine and Metabolic Research.Research output: Contribution to journal › Review article › peer-review
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Comparison of mechanisms of angiostasis caused by the anti-inflammatory steroid 5α-tetrahydrocorticosterone versus conventional glucocorticoids
Abernethie, A. J., Gastaldello, A., Maltese, G., Morgan, R. A., Mcinnes, K. J., Small, G. R., Walker, B. R., Livingstone, D. E. W., Hadoke, P. W. F. & Andrew, R., 20 Jun 2022, (E-pub ahead of print) In: European Journal of Pharmacology. p. 175111Research output: Contribution to journal › Article › peer-review
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Increased adipose tissue indices of androgen catabolism and aromatization in women with metabolic dysfunction
Ostinelli, G., Laforest, S., Denham, S. G., Gauthier, M-F., Virginie, D-L., Scott, E., Hould, F-S., Marceau, S., Homer, N. Z. M., Bégin, C., Andrew, R. & Tchernof, A., 3 May 2022, In: The Journal of Clinical Endocrinology & Metabolism (JCEM).Research output: Contribution to journal › Article › peer-review
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ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans
Kyle, C. J., Nixon, M., Homer, N. Z. M., Morgan, R. A., Andrew, R., Stimson, R. H. & Walker, B. R., 1 Mar 2022, In: Metabolism. 128, 155118.Research output: Contribution to journal › Article › peer-review
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2021
Derivatization with 2-Hydrazino-1-methylpyridine Enhances Sensitivity of Analysis of 5α-Dihydrotestosterone in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry
Faqehi, A. M., Denham, S., Naredo, G., Cobice, D. F., Khan, S., Simpson, J., Sabil, G., Upreti, R., Gibb, F., Homer, N. Z. M. & Andrew, R., 23 Jan 2021, (E-pub ahead of print) In: Journal of Chromatography A.Research output: Contribution to journal › Article › peer-review
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2020
Effects of Obesity And Insulin on Tissue-Specific Recycling Between Cortisol And Cortisone in Men
Anderson, A., Andrew, R., Homer, N. Z. M., Hughes, K., Boyle, L., Nixon, M., Karpe, F., Stimson, R. H. & Walker, B., 3 Dec 2020, (E-pub ahead of print) In: The Journal of Clinical Endocrinology & Metabolism (JCEM).Research output: Contribution to journal › Article › peer-review
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Mass spectrometry: future opportunities for profiling and imaging steroids and steroid metabolites
Andrew, R. & Homer, N. Z. M., 18 Nov 2020, (E-pub ahead of print) In: Current Opinion in Endocrine and Metabolic Research.Research output: Contribution to journal › Article › peer-review
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Insights from the Menstrual Cycle in Pulmonary Arterial Hypertension
Baird, G. L., Walsh, T., Aliotta, J., Allahua, M., Andrew, R., Bourjeily, G., Brodsky, A., Denver, N., Dooner, M., Harrington, E. O., Klinger, J. R., MacLean, M. R., Mullin, C. J., Pereira, M., Poppas, A., Whittenhall, M. & Ventetuolo, C. E., 4 Sept 2020, (E-pub ahead of print) In: Annals of the American Thoracic Society.Research output: Contribution to journal › Article › peer-review
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Sexual dimorphism in cortisol metabolism throughout pubertal development: a longitudinal study
Van Keulen, B. J., Dolan, C. V., Van Der Voorn, B., Andrew, R., Walker, B. R., Hulshoff Poll, H., Boomsma, D. I., Rotteveel, J. & Finken, M. J. J., 7 Jun 2020, In: Endocrine connections.Research output: Contribution to journal › Article › peer-review
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Exploring the Temporal Relation between Body Mass Index and Corticosteroid Metabolite Excretion in Childhood
Van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B. R., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & Finken, M. J. J., 23 May 2020, In: Nutrients. 12, 5, p. 1525Research output: Contribution to journal › Article › peer-review
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Estrogen Signaling and Portopulmonary Hypertension: The Pulmonary Vascular Complications of Liver Disease Study (PVCLD2)
Al-Naamani, N., Krowka, M. J., Forde, K. A., Krok, K. L., Feng, R., Heresi, G. A., Dweik, R. A., Bartolome, S., Bull, T. M., Roberts, K. E., Austin, E. D., Hemnes, A. R., Patel, M. J., Oh, J. K., Lin, G., Doyle, M. F., Denver, N., Andrew, R., MacLean, M. R., Fallon, M. B., & 1 others, 14 May 2020, In: Hepatology.Research output: Contribution to journal › Article › peer-review
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Diet-induced weight loss alters hepatic glucocorticoid metabolism in type 2 diabetes mellitus
Stomby, A., Otten, J., Ryberg, M., Andrew, R., Walker, B. R. & Olsson, T., 1 Apr 2020, (E-pub ahead of print) In: European Journal of Endocrinology. 182, 4, p. 447-457Research output: Contribution to journal › Article › peer-review
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Long-term stability of cortisol production and metabolism throughout adolescence: longitudinal twin study
van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & Finken, M. JJ., 25 Mar 2020, In: Twin Research and Human Genetics.Research output: Contribution to journal › Article › peer-review
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Highlights into the pharmacology of nutraceuticals
Andrew, R. & Izzo, A., 4 Mar 2020, In: British Journal of Pharmacology. 177, 6, p. 1209-1211Research output: Contribution to journal › Editorial › peer-review
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Maternal glucocorticoid metabolism across pregnancy: a potential mechanism underlying fetal glucocorticoid exposure
Stoye, D. Q., Andrew, R., Grobman, W. A., Adam, E. K., Wadhwa, P. D., Buss, C., Entringer, S., Miller, G. E., Boardman, J., Seckl, J., Keenan-Devlin, L. S., Borders, A. E. B. & Reynolds, R., 1 Mar 2020, In: The Journal of Clinical Endocrinology & Metabolism (JCEM). 105, 3, dgz313.Research output: Contribution to journal › Article › peer-review
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EXPRESS: Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension
Denver, N., Homer, N. Z., Andrew, R., Harvey, K., Morrell, N., Austin, E. & Maclean, M., 13 Feb 2020, In: Pulmonary circulation. p. 204589402090878Research output: Contribution to journal › Article › peer-review
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CHAPTER 5: Mass Spectrometry Imaging of Lipids
Khan, S. & Andrew, R., 23 Jan 2020, Lipidomics: Current and Emerging Techniques. Griffiths, W. & Wang, Y. (eds.). 7 ed. Royal Society of Chemistry, p. 88-121 34 p. (New Developments in Mass Spectrometry; vol. 2020-January, no. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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MASS SPECTROMETRY IMAGING OF LIPIDS
Khan, S. & Andrew, R., 23 Jan 2020, Lipidomics: Current and Emerging Techniques.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2019
Estrogens and glucocorticoids in mammary adipose tissue: Relationships with body mass index and breast cancer features
Laforest, S., Pelletier, M., Denver, N., Poirier, B., Nguyen, S., Walker, B. R., Durocher, F., Homer, N. Z. M., Diorio, C., Andrew, R. & Tchernof, A., 19 Dec 2019, In: The Journal of Clinical Endocrinology & Metabolism (JCEM). 105, 4, p. e1504–e1516Research output: Contribution to journal › Article › peer-review
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Simultaneous quantification of estrogens and glucocorticoids in human adipose tissue by liquid-chromatography-tandem mass spectrometry
Laforest, S., Pelletier, M., Denver, N., Poirier, B., Nguyen, S., Walker, B. R., Durocher, F., Homer, N. Z. M., Diorio, C., Tchernof, A. & Andrew, R., 1 Dec 2019, In: Journal of Steroid Biochemistry and Molecular Biology. 195, 105476.Research output: Contribution to journal › Article › peer-review
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Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography triple quadrupole mass spectrometry
Verma, M., Sooy, K., Just, G., Nixon, M., Morgan, R., Andrew, R., Chapman, K. & Homer, N., 2 Nov 2019, In: Rapid communications in mass spectrometry.Research output: Contribution to journal › Article › peer-review
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Heritability of cortisol production and metabolism throughout adolescence: a twin study
van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & finken, M. JJ., 14 Oct 2019, In: The Journal of Clinical Endocrinology & Metabolism (JCEM).Research output: Contribution to journal › Article › peer-review
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Urinary estrogens as a non-invasive biomarker of viable pregnancy in the giant panda (Ailuropoda melanoleuca)
Wilson, K. S., Wauters, J., Valentine, I., McNeilly, A., Girling, S., Li, R., Li, D., Zhang, H., Rae, M. T., Howie, A. F., Andrew, R. & Duncan, W. C., 4 Sept 2019, In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
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Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
Mak, T. C., Livingstone, D. E., Nixon, M., Walker, B. R. & Andrew, R., 14 Jun 2019, In: Endocrinology .Research output: Contribution to journal › Article › peer-review
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Current strategies for quantification of estrogens in clinical research
Denver, N., Khan, S., Homer, N., MacLean, M. & Andrew, R., 18 May 2019, (E-pub ahead of print) In: Journal of Steroid Biochemistry and Molecular Biology.Research output: Contribution to journal › Article › peer-review
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Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study
Wei, L., Chia-Cheng Lai, E., Kao-Yang, Y-H., Walker, B. R., MacDonald, T. M. & Andrew, R., 10 Apr 2019, In: British Medical Journal (BMJ). 365, 8196, 11 p., l1204.Research output: Contribution to journal › Article › peer-review
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PIPIN: A Feasibility Trial of Pravastatin for the Prevention of Preterm Birth in Women Trial Methods and Protocol.
Whitaker, E. M. H., Whyte, S. A., Norrie, J., Andrew, R., Williams, D., Stock, S. J. & Norman, J. E., 31 Mar 2019, In: Reproductive Sciences. 26, S1, p. 320A-320A 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors
Gibb, F., Dixon, M. J., Clarke, C., Homer, N., Faqehi, A., Andrew, R. & Walker, B., 28 Mar 2019, (E-pub ahead of print) In: The Journal of Clinical Endocrinology & Metabolism (JCEM). 104, 9, p. 3670–3678Research output: Contribution to journal › Article › peer-review
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Data for analysis of catechol estrogen metabolites in human plasma by liquid chromatography tandem mass spectrometry
Andrew, R., Khan, S., Stasinopoulos, I., Church, C., Homer, N. & McLean, M., 8 Mar 2019, (E-pub ahead of print) In: Data in brief.Research output: Contribution to journal › Article › peer-review
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2018
Derivatization enhances analysis of estrogens and their bioactive metabolites in human plasma by liquid chromatography tandem mass spectrometry
Denver, N., Khan, S., Stasinopoulos, I., Church, C., Homer, N. ZM., MacLean, M. R. & Andrew, R., 21 Dec 2018, (E-pub ahead of print) In: Analytica Chimica Acta.Research output: Contribution to journal › Article › peer-review
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Species-specific regulation of angiogenesis by glucocorticoids reveals contrasting effects on inflammatory and angiogenic pathways
Morgan, R., Keen, J., Halligan, D., O'Callaghan, A., Andrew, R., Livingstone, D., Livingstone, D., Abernethie, A., Maltese, G., Walker, B. & Hadoke, P., 15 Feb 2018, In: PLoS ONE. 13, 2, e0192746.Research output: Contribution to journal › Article › peer-review
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Quantification of 11β-hydroxysteroid dehydrogenase 1 kinetics and pharmacodynamic effects of inhibitors in brain using mass spectrometry imaging and stable-isotope tracers in mice
Cobice, D. F., Livingstone, D. E. W., Mcbride, A., Mackay, C. L., Walker, B., Webster, S. P. & Andrew, R., 1 Feb 2018, In: Biochemical Pharmacology. 148, p. 88-99Research output: Contribution to journal › Article › peer-review
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Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease
Taylor, A., Rankin, A. J., McQuarrie, E. P., Freel, E. M., Homer, N., Andrew, R., Jardine, A. G. & Mark, P. B., 25 Jan 2018, (E-pub ahead of print) In: Clinical science. 132, 2Research output: Contribution to journal › Article › peer-review
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